A single-arm, multicenter, phase II trial of osimertinib in patients with epidermal growth factor receptor exon 18 G719X, exon 20 S768I, or exon 21 L861Q mutations
Villaruz, L.C., Wang, X., Bertino, E.M., Gu, L., Antonia, S.J., Burns, T.F., Clarke, J., Crawford, J., Evans, T.L., Friedland, D.M., Otterson, G.A., Ready, N.E., Wozniak, A.J., Stinchcombe, T.E.
Published in ESMO open (01.04.2023)
Published in ESMO open (01.04.2023)
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Inhibition of DNA repair with MGMT pseudosubstrates: phase I study of lomeguatrib in combination with dacarbazine in patients with advanced melanoma and other solid tumours
Tawbi, H A, Villaruz, L, Tarhini, A, Moschos, S, Sulecki, M, Viverette, F, Shipe-Spotloe, J, Radkowski, R, Kirkwood, J M
Published in British journal of cancer (06.09.2011)
Published in British journal of cancer (06.09.2011)
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Journal Article
MC13-0078 PARP1 variants associated with response to Temozolomide in metastatic melanoma patients
Sedgewick, A, Romkes, M, Buch, S, Villaruz, L, Abecassis, I, Saul, M, Kirkwood, J.M, Benos, P.V, Tawbi, H
Published in European journal of cancer (1990) (01.11.2013)
Published in European journal of cancer (1990) (01.11.2013)
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1346P A population-level prognostic score model for early acquired resistance to frontline anti-PD-(L)1 therapy in metastatic non-small cell lung cancer (NSCLC)
Murray, J.C., Huang, Q., Hu, C., Curran, E., Wong, C., Glatz, L., Wang, T., Hasan, A., Villaruz, L., Schoenfeld, A.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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Journal Article
First-Line Nivolumab in Stage IV or Recurrent Non–Small-Cell Lung Cancer
Carbone, David P, Reck, Martin, Paz-Ares, Luis, Creelan, Benjamin, Horn, Leora, Steins, Martin, Felip, Enriqueta, van den Heuvel, Michel M, Ciuleanu, Tudor-Eliade, Badin, Firas, Ready, Neal, Hiltermann, T. Jeroen N, Nair, Suresh, Juergens, Rosalyn, Peters, Solange, Minenza, Elisa, Wrangle, John M, Rodriguez-Abreu, Delvys, Borghaei, Hossein, Blumenschein, George R, Villaruz, Liza C, Havel, Libor, Krejci, Jana, Corral Jaime, Jesus, Chang, Han, Geese, William J, Bhagavatheeswaran, Prabhu, Chen, Allen C, Socinski, Mark A
Published in The New England journal of medicine (22.06.2017)
Published in The New England journal of medicine (22.06.2017)
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OA10.05 Phase I Trial of DLL3/CD3 IgG-Like T-Cell Engager BI 764532 in Patients with DLL3-Positive Tumors: Patients with LCNEC
Wermke, M., Gambardella, V., Kuboki, Y., Alese, O.B., Morgensztern, D., Sayehli, C., Sanmamed, M.F., Arriola, E., Wolf, J., Villaruz, L., Studeny, M., Bouzaggou, M., Fang, X., Felip, E.
Published in Journal of thoracic oncology (01.10.2024)
Published in Journal of thoracic oncology (01.10.2024)
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Journal Article
P3.06E.01 Evaluation of the Immune Landscape of Patients with Adenosquamous NSCLC (LUAS)
Lee, M., Adeyelu, T., Wang, S., Elliott, A., Vanderwalde, A., Villaruz, L., Khan, H., Herzberg, B., Kim, S.Y., Ma, P., Liu, S., Halmos, B., Cheng, H.
Published in Journal of thoracic oncology (01.10.2024)
Published in Journal of thoracic oncology (01.10.2024)
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Journal Article
670P Phase I trial of the delta-like ligand-3 (DLL3)/CD3 IgG-Like T cell engager BI 764532 in patients (pts) with DLL3-positive tumors: Updated data
Wermke, M., Gambardella, V., Kuboki, Y., Felip, E., Sanmamed, M.F., Alese, O., Sayehli, C.M., Arriola Aperribay, E., Wolf, J., Villaruz, L., Studeny, M., Bouzaggou, M., Fang, X., Morgensztern, D.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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1309P A genomic scar based signature (HRDsig) and biallelic BRCA alterations identify a homologous recombination deficiency (HRD) phenotype of non-small cell lung cancer (NSCLC) potentially actionable to the PARP inhibitor rucaparib: Post-hoc analysis of lung-MAP substudy S1900A
Riess, J.W., Miao, J., Wheatley-Price, P., Reckamp, K.L., Kozono, D., Redman, M.W., Edelman, M.J., Faller, B., Villaruz, L., Corum, L., Gowda, A., Srkalovic, G., Osarogiagbon, R., Baumgart, M., Gandara, D.R., Sokol, E.S., Borghaei, H., Gray, J.E., Herbst, R.S., Kelly, K.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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1047P Lung-MAP S1800A: Exploratory analysis of prior immunotherapy outcomes on OS with ramucirumab plus pembrolizumab for NSCLC with PD on prior ICI
Reckamp, K., Redman, M.W., Dragnev, K., Villaruz, L., Faller, B., Al Baghdadi, T., Hines, S., Minichiello, K., Gandara, D.R., Kelly, K., Herbst, R.S.
Published in Annals of oncology (01.09.2022)
Published in Annals of oncology (01.09.2022)
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Journal Article
P3.12D.11 Phase 1/2, Dose-expansion Study of AMG 193, an MTA-cooperative PRMT5 Inhibitor, In MTAP-deleted NSCLC
Sacher, A., Addeo, A., Doi, T., Chu, Q., El Helali, A., Villaruz, L., Prenen, H., Vokes, N., Rodon, J., Durm, G., Lebellec, L., O’Neil, B., Dy, G., Eggert, T., Keyvanjah, K., Gadgeel, S.
Published in Journal of thoracic oncology (01.10.2024)
Published in Journal of thoracic oncology (01.10.2024)
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Journal Article
MA11.09 Phase II Trial of Atezolizumab Plus Cobimetinib in PD-(L)1 Inhibitor Resistant NSCLC: NCI ETCTN Study 10166
Saltos, A., Hall, R., Tan, M., Kim, C., Saxena, A., He, K., Mamdani, H., Lycan, T.W., Villaruz, L., Khalil, M., Aljumaily, R., Tanvetyanon, T., Gentzler, R.D., Ma, B., Ozisik, D., Murray, J.A., Liu, S.V.
Published in Journal of thoracic oncology (01.10.2024)
Published in Journal of thoracic oncology (01.10.2024)
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1302P MET×MET bispecific antibody davutamig (REGN5093) for MET-altered advanced non-small cell lung cancer (aNSCLC): Update from a first-in-human (FIH) study
Cho, B.C., Ahn, M-J., Kim, T.M., Kim, S-W., Han, J-Y., Kim, C., Shim, B., Ricordel, C., Drilon, A.E., Pujol, J-L., Gray, J.E., Villaruz, L., Blumenschein, G., Perez, J., Modi, D.A., Kaul, M., Patel, S., Hao, Y., Kim, E., Magnan, H.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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Journal Article
604O Phase I dose escalation and initial dose expansion results of AMG 193: A MTA-cooperative PRMT5 inhibitor, in patients (pts) with MTAP-deleted solid tumors
Sacher, A.G., Villalona-Calero, M., O’Neil, B.H., Rodon, J., Doi, T., Postel-Vinay, S., Ghiringhelli, F., Yamamoto, N., Wahlroos, S., Villaruz, L., El-Helali, A., Fujiwara, Y., Addeo, A., Lin, C-C., Fontana, E., Chuang, C-H., Liu, C., Eggert, T., Penel, N., Prenen, H.
Published in Annals of oncology (01.09.2024)
Published in Annals of oncology (01.09.2024)
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Journal Article
P2.02-047 Comparison of PD-L1 Immunohistochemistry Assays and Response to PD-L1 Inhibitors
Dacic, S., Ancevski, K., Aberrbock, S., Herbst, C., Villaruz, L.
Published in Journal of thoracic oncology (01.11.2017)
Published in Journal of thoracic oncology (01.11.2017)
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Journal Article
P2.31-05 Determining Lines of Therapy in Patients with Metastatic Non-Small Cell Lung Cancer Using Real-World Data
Grady, C.B., Sun, L., Reuss, J.E., Cass, A., Liu, G., Patel, D., Liu, S., Montenegro, G.B., Patil, T., Nieva, J., Herrmann, A., Marrone, K., Lam, V., Schwartzman, W., Villaruz, L., Miller, K.L., Camidge, D.R., Aggarwal, C., Hwang, W.-T., Marmarelis, M.E.
Published in Journal of thoracic oncology (01.11.2023)
Published in Journal of thoracic oncology (01.11.2023)
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OA02.04 Phase 1/2 Randomized Trial of Anetumab Ravtansine and Pembrolizumab Compared to Pembrolizumab for Pleural Mesothelioma - NCT03126630
Mansfield, A.S., Yin, J.V., Bradbury, P., Kwiatkowski, D., Patel, S., Bazhenova, L., Forde, P., Lou, Y., Villaruz, L., Arnold, S., Khalil, M., Kindler, H., Koczywas, M., Pacheco, J., Rolfo, C., Xia, B., Mikula, E.R., Sharon, E., Moscow, J., Hassan, R.
Published in Journal of thoracic oncology (01.11.2023)
Published in Journal of thoracic oncology (01.11.2023)
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A single-arm, open-label, phase 2 study of nab-paclitaxel and carboplatin chemotherapy plus necitumumab in the first-line treatment of patients with stage IV squamous non-small cell lung cancer (NSCLC)
Socinski, M., Gil, M., Shahidi, J., Chao, G.Y., Villaruz, L.
Published in Annals of oncology (01.10.2016)
Published in Annals of oncology (01.10.2016)
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FP14.06 Multicenter Analysis of Mechanisms of Resistance to Osimertinib (O) in EGFR Mutated NSCLC: An ATOMIC Registry Study
Bauml, J.M., Mick, R., Mccoach, C., Weiss, J., Marrone, K., Nieva, J., Villaruz, L., Levy, B., Moreno, R., Murkherji, R., Sun, F., Schwartzman, W., Shaverdashvili, K., Wang, X., Shah, M., Woodley, J., Miller, N., Succe, C., Ullah, T., Lovly, C., Doebele, R., Iams, W., Horn, L., Dowell, J., Liu, G., Leighl, N., Patil, T., Liu, S., Velcheti, V., Aisner, D., Camidge, R.
Published in Journal of thoracic oncology (01.03.2021)
Published in Journal of thoracic oncology (01.03.2021)
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