The tangle of nuclear receptors that controls xenobiotic metabolism and transport: crosstalk and consequences
Pascussi, Jean-Marc, Gerbal-Chaloin, Sabine, Duret, Cédric, Daujat-Chavanieu, Martine, Vilarem, Marie-José, Maurel, Patrick
Published in Annual review of pharmacology and toxicology (01.01.2008)
Published in Annual review of pharmacology and toxicology (01.01.2008)
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Journal Article
A novel pregnane X receptor and S14‐mediated lipogenic pathway in human hepatocyte
Moreau, Amélie, Téruel, Christelle, Beylot, Michel, Albalea, Valérie, Tamasi, Viola, Umbdenstock, Thierry, Parmentier, Yannick, Sa‐Cunha, Antonio, Suc, Bertrand, Fabre, Jean‐Michel, Navarro, Francis, Ramos, Jeanne, Meyer, Urs, Maurel, Patrick, Vilarem, Marie‐José, Pascussi, Jean‐Marc
Published in Hepatology (Baltimore, Md.) (01.06.2009)
Published in Hepatology (Baltimore, Md.) (01.06.2009)
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Journal Article
Hepatic Expression of Thyroid Hormone-Responsive Spot 14 Protein Is Regulated by Constitutive Androstane Receptor (NR1I3)
Breuker, Cyril, Moreau, Amélie, Lakhal, Laila, Tamasi, Viola, Parmentier, Yannick, Meyer, Urs, Maurel, Patrick, Lumbroso, Serge, Vilarem, Marie-José, Pascussi, Jean-Marc
Published in Endocrinology (Philadelphia) (01.04.2010)
Published in Endocrinology (Philadelphia) (01.04.2010)
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Journal Article
Ketoconazole and Miconazole Are Antagonists of the Human Glucocorticoid Receptor: Consequences on the Expression and Function of the Constitutive Androstane Receptor and the Pregnane X Receptor
Cedric Duret, Martine Daujat-Chavanieu, Jean-Marc Pascussi, Lydiane Pichard-Garcia, Patrick Balaguer, Jean-Michel Fabre, Marie-José Vilarem, Patrick Maurel, Sabine Gerbal-Chaloin
Published in Molecular pharmacology (01.07.2006)
Published in Molecular pharmacology (01.07.2006)
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Journal Article
Interleukin 1β inhibits CAR‐induced expression of hepatic genes involved in drug and bilirubin clearance
Assenat, Eric, Gerbal‐Chaloin, Sabine, Larrey, Dominique, Saric, Jean, Fabre, Jean‐Michel, Maurel, Patrick, Vilarem, Marie‐José, Pascussi, Jean Marc
Published in Hepatology (Baltimore, Md.) (01.10.2004)
Published in Hepatology (Baltimore, Md.) (01.10.2004)
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Journal Article
Transcriptional Analysis of the Orphan Nuclear Receptor Constitutive Androstane Receptor (NR1I3) Gene Promoter: Identification of a Distal Glucocorticoid Response Element
Pascussi, Jean Marc, Busson-Le Coniat, Maryvonne, Maurel, Patrick, Vilarem, Marie-José
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2003)
Published in Molecular endocrinology (Baltimore, Md.) (01.01.2003)
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Journal Article
The Small Heterodimer Partner Interacts with the Pregnane X Receptor and Represses Its Transcriptional Activity
Ourlin, Jean Claude, Lasserre, Fredéric, Pineau, Thierry, Fabre, Jean Michel, Sa-Cunha, Antonio, Maurel, Patrick, Vilarem, Marie-José, Pascussi, Jean Marc
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2003)
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2003)
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Journal Article
Interleukin-6 Negatively Regulates the Expression of Pregnane X Receptor and Constitutively Activated Receptor in Primary Human Hepatocytes
Pascussi, Jean-Marc, Gerbal-Chaloin, Sabine, Pichard-Garcia, Lydiane, Daujat, Martine, Fabre, Jean-Michel, Maurel, Patrick, Vilarem, Marie-José
Published in Biochemical and biophysical research communications (11.08.2000)
Published in Biochemical and biophysical research communications (11.08.2000)
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Journal Article
Identification of proteomic changes during human liver development by 2D-DIGE and mass spectrometry
Brizard, Jean Paul, Ramos, Jeanne, Robert, Agnés, Lafitte, Daniel, Bigi, Nicole, Sarda, Pierre, Laoudj-Chenivesse, Dalila, Navarro, Francis, Blanc, Pierre, Assenat, Eric, Maurel, Patrick, Pascussi, Jean-Marc, Vilarem, Marie-José
Published in Journal of hepatology (01.07.2009)
Published in Journal of hepatology (01.07.2009)
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Journal Article
Cytoprotective properties of α-tocopherol are related to gene regulation in cultured d-galactosamine-treated human hepatocytes
González, Raul, Collado, Juan Antonio, Nell, Sandra, Briceño, Javier, Tamayo, María José, Fraga, Enrique, Bernardos, Ángel, López-Cillero, Pedro, Pascussi, Jean Marc, Rufián, Sebastián, Vilarem, Marie-José, Mata, Manuel De la, Brigelius-Flohe, Regina, Maurel, Patrick, Muntané, Jordi
Published in Free radical biology & medicine (15.11.2007)
Published in Free radical biology & medicine (15.11.2007)
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Journal Article
Response to Zhou et al
Pascussi, Jean-Marc, Maurel, Patrick, Vilarem, Marie-Jose
Published in The Journal of clinical investigation (01.10.2006)
Published in The Journal of clinical investigation (01.10.2006)
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Journal Article
Expression of CYP3A4, CYP2B6, and CYP2C9 is regulated by the vitamin D receptor pathway in primary human hepatocytes
Drocourt, Lionel, Ourlin, Jean-Claude, Pascussi, Jean-Marc, Maurel, Patrick, Vilarem, Marie-José
Published in The Journal of biological chemistry (12.07.2002)
Published in The Journal of biological chemistry (12.07.2002)
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Journal Article
Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators
Pascussi, J M, Drocourt, L, Fabre, J M, Maurel, P, Vilarem, M J
Published in Molecular pharmacology (01.08.2000)
Published in Molecular pharmacology (01.08.2000)
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Journal Article
Colchicine Down-Regulates Cytochrome P450 2B6, 2C8, 2C9, and 3A4 in Human Hepatocytes by Affecting Their Glucocorticoid Receptor-Mediated Regulation
Dvorak, Zdenek, Modriansky, Martin, Pichard-Garcia, Lydiane, Balaguer, Patrick, Vilarem, Marie-Jose, Ulrichová, Jitka, Maurel, Patrick, Pascussi, Jean-Marc
Published in Molecular pharmacology (01.07.2003)
Published in Molecular pharmacology (01.07.2003)
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Journal Article
Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor
Pascussi, J M, Drocourt, L, Gerbal-Chaloin, S, Fabre, J M, Maurel, P, Vilarem, M J
Published in European journal of biochemistry (01.12.2001)
Published in European journal of biochemistry (01.12.2001)
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Journal Article
Pathophysiological Factors Affecting CAR Gene Expression
Pascussi, Jean Marc, Dvorák, Zdenek, Gerbal-Chaloin, Sabine, Assenat, Eric, Maurel, Patrick, Vilarem, Marie José
Published in Drug metabolism reviews (01.01.2003)
Published in Drug metabolism reviews (01.01.2003)
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Journal Article
Conference Proceeding
Transcriptional regulation of CYP2C9 gene. Role of glucocorticoid receptor and constitutive androstane receptor
Gerbal-Chaloin, Sabine, Daujat, Martine, Pascussi, Jean-Marc, Pichard-Garcia, Lydiane, Vilarem, Marie-Jose, Maurel, Patrick
Published in The Journal of biological chemistry (04.01.2002)
Published in The Journal of biological chemistry (04.01.2002)
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Journal Article