Cross-talk between xenobiotic detoxication and other signalling pathways: clinical and toxicological consequences
Pascussi, J.-M., Gerbal-Chaloin, S., Drocourt, L., Assénat, E., Larrey, D., Pichard-Garcia, L., Vilarem, M.-J., Maurel, P.
Published in Xenobiotica (01.07.2004)
Published in Xenobiotica (01.07.2004)
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Journal Article
Dual effect of dexamethasone on CYP3A4 gene expression in human hepatocytes. Sequential role of glucocorticoid receptor and pregnane X receptor
Pascussi, J M, Drocourt, L, Gerbal-Chaloin, S, Fabre, J M, Maurel, P, Vilarem, M J
Published in European journal of biochemistry (01.12.2001)
Published in European journal of biochemistry (01.12.2001)
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Journal Article
The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors
Pascussi, J.M., Gerbal-Chaloin, S., Drocourt, L., Maurel, P., Vilarem, M.J.
Published in BBA - General Subjects (17.02.2003)
Published in BBA - General Subjects (17.02.2003)
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Book Review
Journal Article
Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchicine: focus on PXR, CAR, and GR in primary human hepatocytes
Dvorák, Z, Maurel, P, Vilarem, M-J, Ulrichová, J, Modrianský, M
Published in Cell biology and toxicology (01.03.2007)
Published in Cell biology and toxicology (01.03.2007)
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Journal Article
Dexamethasone induces pregnane X receptor and retinoid X receptor-alpha expression in human hepatocytes: synergistic increase of CYP3A4 induction by pregnane X receptor activators
Pascussi, J M, Drocourt, L, Fabre, J M, Maurel, P, Vilarem, M J
Published in Molecular pharmacology (01.08.2000)
Published in Molecular pharmacology (01.08.2000)
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Journal Article
Role of the liver-enriched transcription factors C/EBPα and DBP in the expression of human CYP3A4 and CYP3A7
Ourlin, Jean Claude, Jounaïdi, Youssef, Maurel, Patrick, Vilarem, Marie-José
Published in Journal of hepatology (1997)
Published in Journal of hepatology (1997)
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Journal Article
Conference Proceeding
Interleukin-6 Negatively Regulates the Expression of Pregnane X Receptor and Constitutively Activated Receptor in Primary Human Hepatocytes
Pascussi, Jean-Marc, Gerbal-Chaloin, Sabine, Pichard-Garcia, Lydiane, Daujat, Martine, Fabre, Jean-Michel, Maurel, Patrick, Vilarem, Marie-José
Published in Biochemical and biophysical research communications (11.08.2000)
Published in Biochemical and biophysical research communications (11.08.2000)
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Journal Article
The Small Heterodimer Partner Interacts with the Pregnane X Receptor and Represses Its Transcriptional Activity
Ourlin, Jean Claude, Lasserre, Fredéric, Pineau, Thierry, Fabre, Jean Michel, Sa-Cunha, Antonio, Maurel, Patrick, Vilarem, Marie-José, Pascussi, Jean Marc
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2003)
Published in Molecular endocrinology (Baltimore, Md.) (01.09.2003)
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Journal Article
Calcium Channel Modulators of the Dihydropyridine Family Are Human Pregnane X Receptor Activators and Inducers of CYP3A, CYP2B, and CYP2C in Human Hepatocytes
DROCOURT, Lionel, PASCUSSI, Jean-Marc, ASSENAT, Eric, FABRE, Jean-Michel, MAUREL, Patrick, VILAREM, Marie-Jose
Published in Drug metabolism and disposition (01.10.2001)
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Published in Drug metabolism and disposition (01.10.2001)
Journal Article
Evidence for the Presence of a Functional Pregnane X Receptor Response Element in the CYP3A7 Promoter Gene
Pascussi, Jean-Marc, Jounaidi, Youssef, Drocourt, Lionel, Domergue, Jacques, Balabaud, Charles, Maurel, Patrick, Vilarem, Marie-Josée
Published in Biochemical and biophysical research communications (05.07.1999)
Published in Biochemical and biophysical research communications (05.07.1999)
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Journal Article
Expression and transcriptional activities of nuclear receptors involved in regulation of drug-metabolizing enzymes are not altered by colchiceine: Focus on PXR, CAR, and GR in primary human hepatocytes
Dvořák, Z., Maurel, P., Vilarem, M.-J., Ulrichová, J., Modrianský, M.
Published in Cell biology and toxicology (01.03.2007)
Published in Cell biology and toxicology (01.03.2007)
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Journal Article
Functional characterization of the promoter of pp63, a gene encoding a natural inhibitor of the insulin receptor tyrosine kinase
Falquerho, Laurence, Paquereau, Laurent, Vilarem, Marie José, Galas, Simon, Patey, Gilles, Le Cam, Alphonse
Published in Nucleic acids research (25.04.1992)
Published in Nucleic acids research (25.04.1992)
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Journal Article
The antibiotic rifampicin is a nonsteroidal ligand and activator of the human glucocorticoid receptor
Calleja, C, Pascussi, J M, Mani, J C, Maurel, P, Vilarem, M J
Published in Nature medicine (01.01.1998)
Published in Nature medicine (01.01.1998)
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Journal Article
Activation of c-Ki- ras coexists with c- myc amplification in cells from a nude mouse tumor induced by the human breast carcinoma cell line SW 613-S
Carloni, Guido, Champ, Brigitte, Vilarem, Marie-Jose´, Lavialle, Christian, Cassingena, Roland
Published in FEBS letters (20.06.1988)
Published in FEBS letters (20.06.1988)
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Journal Article