Macrophages contribute to the pathogenesis of sclerosing cholangitis in mice
Guicciardi, Maria Eugenia, Trussoni, Christy E., Krishnan, Anuradha, Bronk, Steven F., Lorenzo Pisarello, Maria J., O'Hara, Steven P., Splinter, Patrick L., Gao, Yandong, Vig, Pamela, Revzin, Alexander, LaRusso, Nicholas F., Gores, Gregory J.
Published in Journal of hepatology (01.09.2018)
Published in Journal of hepatology (01.09.2018)
Get full text
Journal Article
Maralixibat for the treatment of PFIC: Long‐term, IBAT inhibition in an open‐label, Phase 2 study
Loomes, Kathleen M., Squires, Robert H., Kelly, Deirdre, Rajwal, Sanjay, Soufi, Nisreen, Lachaux, Alain, Jankowska, Irena, Mack, Cara, Setchell, Kenneth D. R., Karthikeyan, Palaniswamy, Kennedy, Ciara, Dorenbaum, Alejandro, Desai, Nirav K., Garner, Will, Jaecklin, Thomas, Vig, Pamela, Miethke, Alexander, Thompson, Richard J.
Published in Hepatology communications (01.09.2022)
Published in Hepatology communications (01.09.2022)
Get full text
Journal Article
Serum Bile Acid Profiling and Mixed Model Analysis Reveal Biomarkers Associated with Pruritus Reduction in Maralixibat-Treated Patients with BSEP Deficiency
Zhao, Xueheng, Zhang, Wujuan, Vig, Pamela, Kostrub, Cory, Setchell, Kenneth D R
Published in Metabolites (01.10.2022)
Published in Metabolites (01.10.2022)
Get full text
Journal Article
Efficacy and Safety of Cenicriviroc in Patients With Primary Sclerosing Cholangitis: PERSEUS Study
Eksteen, Bertus, Bowlus, Christopher L., Montano‐Loza, Aldo J., Lefebvre, Eric, Fischer, Laurent, Vig, Pamela, Martins, Eduardo Bruno, Ahmad, Jawad, Yimam, Kidist K., Pockros, Paul J., Feld, Jordan J., Minuk, Gerald, Levy, Cynthia
Published in Hepatology communications (01.03.2021)
Published in Hepatology communications (01.03.2021)
Get full text
Journal Article
The Critical Role of Chemokine (C-C Motif) Receptor 2-Positive Monocytes in Autoimmune Cholangitis
Reuveni, Debby, Gore, Yael, Leung, Patrick S C, Lichter, Yael, Moshkovits, Itay, Kaminitz, Ayelet, Brazowski, Eli, Lefebvre, Eric, Vig, Pamela, Varol, Chen, Halpern, Zamir, Shibolet, Oren, Gershwin, Merrill Eric, Zigmond, Ehud
Published in Frontiers in immunology (15.08.2018)
Published in Frontiers in immunology (15.08.2018)
Get full text
Journal Article
P142: Efficacy, safety and tolerability of chenodeoxycholic acid in adult patients with cerebrotendinous xanthomatosis (RESTORE): A randomized, placebo-controlled phase 3 study
DeBarber, Andrea, Kisanuki, Yaz, Nobrega, Paulo, Himes, Ryan, Jayadev, Suman, Bernat, John, Prakash, Vikram, Gibson, James, Larson, Austin, Sgobbi, Paulo, Murphy, Edward, Fedor, Brian, Po Foo, Cheryl Wong, Dutta, Rana, Imperiale, Michael, Terner-Rosenthal, Jolan, Garner, Will, Vig, Pamela, Duell, P. Barton, Perez, Sarah, Ramdhani, Ritesh, Saute, Jonas
Published in Genetics in Medicine Open (2024)
Published in Genetics in Medicine Open (2024)
Get full text
Journal Article
The sources of parenchymal regeneration after chronic hepatocellular liver injury in mice
VIG, Pamela, RUSSO, Francesco P, EDWARDS, Robert J, TADROUS, Paul J, WRIGHT, Nicholas A, THOMAS, Howard C, ALISON, Malcolm R, FORBES, Stuart J
Published in Hepatology (Baltimore, Md.) (01.02.2006)
Published in Hepatology (Baltimore, Md.) (01.02.2006)
Get full text
Journal Article
Hepatic stem cells
Forbes, Stuart, Vig, Pamela, Poulsom, Richard, Thomas, Howard, Alison, Malcolm
Published in The Journal of pathology (01.07.2002)
Published in The Journal of pathology (01.07.2002)
Get full text
Journal Article
Pharmacological Inhibition of CCR2/5 Signaling Prevents and Reverses Alcohol‐Induced Liver Damage, Steatosis, and Inflammation in Mice
Ambade, Aditya, Lowe, Patrick, Kodys, Karen, Catalano, Donna, Gyongyosi, Benedek, Cho, Yeonhee, Iracheta‐Vellve, Arvin, Adejumo, Adeyinka, Saha, Banishree, Calenda, Charles, Mehta, Jeeval, Lefebvre, Eric, Vig, Pamela, Szabo, Gyongyi
Published in Hepatology (Baltimore, Md.) (01.03.2019)
Published in Hepatology (Baltimore, Md.) (01.03.2019)
Get full text
Journal Article
THU-094 Clinical benefits with maralixibat for patients with Alagille syndrome are durable through 7 years of treatment: data from the MERGE study
Kamath, Binita M., Gonzalès, Emmanuel, Kelly, Deirdre, Mogul, Douglas B., Garner, Will, Vig, Pamela, Jacquemin, Emmanuel
Published in Journal of hepatology (01.06.2024)
Published in Journal of hepatology (01.06.2024)
Get full text
Journal Article
A randomized, placebo‐controlled trial of cenicriviroc for treatment of nonalcoholic steatohepatitis with fibrosis
Friedman, Scott L., Ratziu, Vlad, Harrison, Stephen A., Abdelmalek, Manal F., Aithal, Guruprasad P., Caballeria, Juan, Francque, Sven, Farrell, Geoffrey, Kowdley, Kris V., Craxi, Antonio, Simon, Krzysztof, Fischer, Laurent, Melchor‐Khan, Liza, Vest, Jeffrey, Wiens, Brian L., Vig, Pamela, Seyedkazemi, Star, Goodman, Zachary, Wong, Vincent Wai‐Sun, Loomba, Rohit, Tacke, Frank, Sanyal, Arun, Lefebvre, Eric
Published in Hepatology (Baltimore, Md.) (01.05.2018)
Published in Hepatology (Baltimore, Md.) (01.05.2018)
Get full text
Journal Article
Maralixibat leads to significant reductions in bilirubin for patients with progressive familial intrahepatic cholestasis: data from MARCH-PFIC
D’Antiga, Lorenzo, Miethke, Alexander, Mogul, Douglas, Nunes, Tiago, Garner, Will, Vig, Pamela, Thompson, Richard
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
OS-072 - Maralixibat leads to significant reductions in bilirubin for patients with progressive familial intrahepatic cholestasis: data from MARCH-PFIC
D’Antiga, Lorenzo, Miethke, Alexander, Mogul, Douglas, Nunes, Tiago, Garner, Will, Vig, Pamela, Thompson, Richard
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
WED-252 - Maralixibat leads to significant reductions in pruritus and improvements in sleep for children with progressive familial intrahepatic cholestasis: data from MARCH-PFIC
Thompson, Richard, Mogul, Douglas, Nunes, Tiago, Garner, Will, Vig, Pamela, Miethke, Alexander
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
Maralixibat leads to significant reductions in pruritus and improvements in sleep for children with progressive familial intrahepatic cholestasis: data from MARCH-PFIC
Thompson, Richard, Mogul, Douglas, Nunes, Tiago, Garner, Will, Vig, Pamela, Miethke, Alexander
Published in Journal of hepatology (01.06.2023)
Published in Journal of hepatology (01.06.2023)
Get full text
Journal Article
FRI131 - Psychometric evaluation of the adult itch reported outcome tool, a worst-itch numeric rating scale in adults with cholestatic liver disease
Foster, Brandon, Andrae, David, Vig, Pamela, McKibben, Andrew, Bowlus, Christopher
Published in Journal of hepatology (01.08.2020)
Published in Journal of hepatology (01.08.2020)
Get full text
Journal Article