Amino acids as promoieties in prodrug design and development
Vig, Balvinder S., Huttunen, Kristiina M., Laine, Krista, Rautio, Jarkko
Published in Advanced drug delivery reviews (01.10.2013)
Published in Advanced drug delivery reviews (01.10.2013)
Get full text
Journal Article
Assessing the Risk of pH-Dependent Absorption for New Molecular Entities: A Novel in Vitro Dissolution Test, Physicochemical Analysis, and Risk Assessment Strategy
Mathias, Neil R, Xu, Yan, Patel, Dhaval, Grass, Michael, Caldwell, Brett, Jager, Casey, Mullin, Jim, Hansen, Luke, Crison, John, Saari, Amy, Gesenberg, Christoph, Morrison, John, Vig, Balvinder, Raghavan, Krishnaswamy
Published in Molecular pharmaceutics (04.11.2013)
Published in Molecular pharmaceutics (04.11.2013)
Get full text
Journal Article
Human PEPT1 Pharmacophore Distinguishes between Dipeptide Transport and Binding
Vig, Balvinder S, Stouch, Terry R, Timoszyk, Julita K, Quan, Yong, Wall, Doris A, Smith, Ronald L, Faria, Teresa N
Published in Journal of medicinal chemistry (15.06.2006)
Published in Journal of medicinal chemistry (15.06.2006)
Get full text
Journal Article
Role of Self-Association and Supersaturation in Oral Absorption of a Poorly Soluble Weakly Basic Drug
Narang, Ajit S., Badawy, Sherif, Ye, Qingmei, Patel, Dhaval, Vincent, Maria, Raghavan, Krishnaswamy, Huang, Yande, Yamniuk, Aaron, Vig, Balvinder, Crison, John, Derbin, George, Xu, Yan, Ramirez, Antonio, Galella, Michael, Rinaldi, Frank A.
Published in Pharmaceutical research (01.08.2015)
Published in Pharmaceutical research (01.08.2015)
Get full text
Journal Article
Amino Acid Ester Prodrugs of the Anticancer Agent Gemcitabine: Synthesis, Bioconversion, Metabolic Bioevasion, and hPEPT1-Mediated Transport
Song, Xueqin, Lorenzi, Philip L, Landowski, Christopher P, Vig, Balvinder S, Hilfinger, John M, Amidon, Gordon L
Published in Molecular pharmaceutics (01.03.2005)
Published in Molecular pharmaceutics (01.03.2005)
Get full text
Journal Article
Amino Acid Ester Prodrugs of the Antiviral Agent 2-Bromo-5,6-dichloro-1-(β-d-ribofuranosyl)benzimidazole as Potential Substrates of hPEPT1 Transporter
Song, Xueqin, Vig, Balvinder S, Lorenzi, Philip L, Drach, John C, Townsend, Leroy B, Amidon, Gordon L
Published in Journal of medicinal chemistry (24.02.2005)
Published in Journal of medicinal chemistry (24.02.2005)
Get full text
Journal Article
Enhanced absorption and growth inhibition with amino acid monoester prodrugs of floxuridine by targeting hPEPT1 transporters
Tsume, Yasuhiro, Vig, Balvinder S, Sun, Jing, Landowski, Christopher P, Hilfinger, John M, Ramachandran, Chandrasekharan, Amidon, Gordon L
Published in Molecules (Basel, Switzerland) (28.06.2008)
Published in Molecules (Basel, Switzerland) (28.06.2008)
Get full text
Journal Article
Proline prodrug of melphalan targeted to prolidase, a prodrug activating enzyme overexpressed in melanoma
MITTAL, Sachin, XUEQIN SONG, VIG, Balvinder S, AMIDON, Gordon L
Published in Pharmaceutical research (01.07.2007)
Published in Pharmaceutical research (01.07.2007)
Get full text
Journal Article
Expression Profile of Drug and Nutrient Absorption Related Genes in Madin-Darby Canine Kidney (MDCK) Cells Grown under Differentiation Conditions
Quan, Yong, Jin, Yisheng, Faria, Teresa N, Tilford, Charles A, He, Aiqing, Wall, Doris A, Smith, Ronald L, Vig, Balvinder S
Published in Pharmaceutics (18.06.2012)
Published in Pharmaceutics (18.06.2012)
Get full text
Journal Article
Amino acid ester prodrugs of floxuridine: synthesis and effects of structure, stereochemistry, and site of esterification on the rate of hydrolysis
Vig, Balvinder S, Lorenzi, Philip J, Mittal, Sachin, Landowski, Christopher P, Shin, Ho-Chul, Mosberg, Henry I, Hilfinger, John M, Amidon, Gordon L
Published in Pharmaceutical research (01.09.2003)
Published in Pharmaceutical research (01.09.2003)
Get full text
Journal Article
Prolidase, a Potential Enzyme Target for Melanoma: Design of Proline-Containing Dipeptide-like Prodrugs
Mittal, Sachin, Song, Xueqin, Vig, Balvinder S, Landowski, Christopher P, Kim, Insook, Hilfinger, John M, Amidon, Gordon L
Published in Molecular pharmaceutics (01.01.2005)
Published in Molecular pharmaceutics (01.01.2005)
Get full text
Journal Article
A Novel High-Throughput PepT1 Transporter Assay Differentiates between Substrates and Antagonists
Faria, Teresa N, Timoszyk, Julita K, Stouch, Terry R, Vig, Balvinder S, Landowski, Christopher P, Amidon, Gordon L, Weaver, C. David, Wall, Doris A, Smith, Ronald L
Published in Molecular pharmaceutics (12.01.2004)
Published in Molecular pharmaceutics (12.01.2004)
Get full text
Journal Article
Interaction of Intestinal Nucleoside Transporter hCNT2 with Amino Acid Ester Prodrugs of Floxuridine and 2-Bromo-5,6-dichloro-1-β-D-ribofuranosylbenzimidazole
Shin, Ho-Chul, Kim, Jin-Suk, Vig, Balvinder Singh, Song, Xueqin, Drach, John Charles, Amidon, Gordon Lewis
Published in Biological & pharmaceutical bulletin (2006)
Published in Biological & pharmaceutical bulletin (2006)
Get full text
Journal Article
Peptide transporter substrate identification during permeability screening in drug discovery: comparison of transfected MDCK-hPepT1 cells to Caco-2 cells
Balimane, Praveen V, Chong, Saeho, Patel, Karishma, Quan, Yong, Timoszyk, Julita, Han, Yong-Hae, Wang, Bonnie, Vig, Balvinder, Faria, Teresa N
Published in Archives of pharmacal research (01.04.2007)
Published in Archives of pharmacal research (01.04.2007)
Get full text
Journal Article
Synthesis and Opioid Activity of Side-Chain-to-Side-Chain Cyclic Dynorphin A-(1−11) Amide Analogues Cyclized between Positions 2 and 5. 1. Substitutions in Position 3
Vig, Balvinder S, Murray, Thomas F, Aldrich, Jane V
Published in Journal of medicinal chemistry (15.01.2004)
Published in Journal of medicinal chemistry (15.01.2004)
Get full text
Journal Article
Functional expression and characterization of a sodium-dependent nucleoside transporter hCNT2 cloned from human duodenum
Shin, Ho-Chul, Landowski, Christopher P., Sun, Duxin, Vig, Balvinder S., Kim, Insook, Mittal, Sachin, Lane, Majella, Rosania, Gustavo, Drach, John C., Amidon, Gordon L.
Published in Biochemical and biophysical research communications (01.08.2003)
Published in Biochemical and biophysical research communications (01.08.2003)
Get full text
Journal Article
Understanding Protein-Interface Interactions of a Fusion Protein at Silicone Oil-Water Interface Probed by Sum Frequency Generation Vibrational Spectroscopy
Li, Yaoxin, Pan, Duohai, Nashine, Vishal, Deshmukh, Smeet, Vig, Balvinder, Chen, Zhan
Published in Journal of pharmaceutical sciences (01.02.2018)
Published in Journal of pharmaceutical sciences (01.02.2018)
Get full text
Journal Article