PI3Kβ inhibition enhances ALK‐inhibitor sensitivity in ALK‐rearranged lung cancer
Talwelkar, Sarang S., Mäyränpää, Mikko I., Schüler, Julia, Linnavirta, Nora, Hemmes, Annabrita, Adinolfi, Simone, Kankainen, Matti, Sommergruber, Wolfgang, Levonen, Anna‐Liisa, Räsänen, Jari, Knuuttila, Aija, Verschuren, Emmy W., Wennerberg, Krister
Published in Molecular oncology (01.05.2023)
Published in Molecular oncology (01.05.2023)
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Journal Article
Cell of Origin Links Histotype Spectrum to Immune Microenvironment Diversity in Non-small-Cell Lung Cancer Driven by Mutant Kras and Loss of Lkb1
Nagaraj, Ashwini S., Lahtela, Jenni, Hemmes, Annabrita, Pellinen, Teijo, Blom, Sami, Devlin, Jennifer R., Salmenkivi, Kaisa, Kallioniemi, Olli, Mäyränpää, Mikko I., Närhi, Katja, Verschuren, Emmy W.
Published in Cell reports (Cambridge) (17.01.2017)
Published in Cell reports (Cambridge) (17.01.2017)
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Journal Article
Effective intravenous delivery of adenovirus armed with TNFα and IL-2 improves anti-PD-1 checkpoint blockade in non-small cell lung cancer
Kudling, Tatiana V., Clubb, James H.A., Pakola, Santeri, Quixabeira, Dafne C.A., Lähdeniemi, Iris A.K., Heiniö, Camilla, Arias, Victor, Havunen, Riikka, Cervera-Carrascon, Victor, Santos, Joao M., Sutinen, Eva, Räsänen, Jari, Borenius, Kristian, Mäyränpää, Mikko I., Aaltonen, Eero, Sorsa, Suvi, Hemminki, Otto, Kanerva, Anna, Verschuren, Emmy W., Ilonen, Ilkka, Hemminki, Akseli
Published in Oncoimmunology (31.12.2023)
Published in Oncoimmunology (31.12.2023)
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Journal Article
Development of an adenosquamous carcinoma histopathology - selective lung metastasis model
Lähdeniemi, Iris A K, Devlin, Jennifer R, Nagaraj, Ashwini S, Talwelkar, Sarang S, Bao, Jie, Linnavirta, Nora, Şeref Vujaklija, Ceren, Kiss, Elina A, Hemmes, Annabrita, Verschuren, Emmy W
Published in Biology open (15.12.2022)
Published in Biology open (15.12.2022)
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Journal Article
Protocol to utilize fresh uncultured human lung tumor cells for personalized functional diagnostics
Talwelkar, Sarang S., Lähdeniemi, Iris A.K., Mäyränpää, Mikko I., Hemmes, Annabrita, Linnavirta, Nora, Räsänen, Jari, Knuuttila, Aija, Wennerberg, Krister, Verschuren, Emmy W.
Published in STAR protocols (16.12.2022)
Published in STAR protocols (16.12.2022)
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Journal Article
The oncogenic potential of Kaposi's sarcoma-associated herpesvirus cyclin is exposed by p53 loss in vitro and in vivo
Verschuren, Emmy W., Klefstrom, Juha, Evan, Gerard I., Jones, Nic
Published in Cancer cell (01.09.2002)
Published in Cancer cell (01.09.2002)
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Journal Article
The putative tumor suppressor gene EphA3 fails to demonstrate a crucial role in murine lung tumorigenesis or morphogenesis
Lahtela, Jenni, Pradhan, Barun, Närhi, Katja, Hemmes, Annabrita, Särkioja, Merja, Kovanen, Panu E, Brown, Arthur, Verschuren, Emmy W
Published in Disease models & mechanisms (01.04.2015)
Published in Disease models & mechanisms (01.04.2015)
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Journal Article
ScType enables fast and accurate cell type identification from spatial transcriptomics data
Nader, Kristen, Tasci, Misra, Ianevski, Aleksandr, Erickson, Andrew, Verschuren, Emmy W, Aittokallio, Tero, Miihkinen, Mitro
Published in Bioinformatics (Oxford, England) (01.07.2024)
Published in Bioinformatics (Oxford, England) (01.07.2024)
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Journal Article
Loss of Emi1-Dependent Anaphase-Promoting Complex/Cyclosome Inhibition Deregulates E2F Target Expression and Elicits DNA Damage-Induced Senescence
Verschuren, Emmy W., Ban, Kenneth H., Masek, Marilyn A., Lehman, Norman L., Jackson, Peter K.
Published in Molecular and Cellular Biology (01.11.2007)
Published in Molecular and Cellular Biology (01.11.2007)
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Journal Article
The role of p53 in suppression of KSHV cyclin-induced lymphomagenesis
VERSCHUREN, Emmy W, HODGSON, J. Graeme, GRAY, Joe W, KOGAN, Scott, JONES, Nic, EVAN, Gerard I
Published in Cancer research (Chicago, Ill.) (15.01.2004)
Published in Cancer research (Chicago, Ill.) (15.01.2004)
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Journal Article
Overexpression of the Anaphase Promoting Complex/Cyclosome Inhibitor Emi1 Leads to Tetraploidy and Genomic Instability of p53-Deficient Cells
Lehman, Norman L., Verschuren, Emmy W., Hsu, Jerry Y., Cherry, Athena M., Jackson, Peter K.
Published in Cell cycle (Georgetown, Tex.) (15.07.2006)
Published in Cell cycle (Georgetown, Tex.) (15.07.2006)
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Journal Article
More than a Tumor Suppressor: E-Cadherin Loss Drives Lung Cancer Metastasis
Devlin, Jennifer R, Verschuren, Emmy W
Published in American journal of respiratory cell and molecular biology (01.08.2018)
Published in American journal of respiratory cell and molecular biology (01.08.2018)
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Journal Article
SOX9 has distinct roles in the formation and progression of different non‐small cell lung cancer histotypes
Bao, Jie, Närhi, Katja, Teodòsio, Ana, Hemmes, Annabrita, Linnavirta, Nora M, Mäyränpää, Mikko I, Salmenkivi, Kaisa, Le Quesne, John, Verschuren, Emmy W
Published in The Journal of pathology (01.09.2021)
Published in The Journal of pathology (01.09.2021)
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Journal Article
Inactivation of AMPK Leads to Attenuation of Antigen Presentation and Immune Evasion in Lung Adenocarcinoma
Gao, Yajing, Päivinen, Pekka, Tripathi, Sushil, Domènech-Moreno, Eva, Wong, Iris P L, Vaahtomeri, Kari, Nagaraj, Ashwini S, Talwelkar, Sarang S, Foretz, Marc, Verschuren, Emmy W, Viollet, Benoit, Yan, Yan, Mäkelä, Tomi P
Published in Clinical cancer research (01.01.2022)
Published in Clinical cancer research (01.01.2022)
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Journal Article
Capturing complex tumour biology in vitro: histological and molecular characterisation of precision cut slices
Davies, Emma J., Dong, Meng, Gutekunst, Matthias, Närhi, Katja, van Zoggel, Hanneke J. A. A., Blom, Sami, Nagaraj, Ashwini, Metsalu, Tauno, Oswald, Eva, Erkens-Schulze, Sigrun, Delgado San Martin, Juan A., Turkki, Riku, Wedge, Stephen R., af Hällström, Taija M., Schueler, Julia, van Weerden, Wytske M., Verschuren, Emmy W., Barry, Simon T., van der Kuip, Heiko, Hickman, John A.
Published in Scientific reports (09.12.2015)
Published in Scientific reports (09.12.2015)
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Journal Article
Oncogenic Ras Disrupts Epithelial Integrity by Activating the Transmembrane Serine Protease Hepsin
Tervonen, Topi A, Pant, Shishir M, Belitškin, Denis, Englund, Johanna I, Närhi, Katja, Haglund, Caj, Kovanen, Panu E, Verschuren, Emmy W, Klefström, Juha
Published in Cancer research (Chicago, Ill.) (15.03.2021)
Published in Cancer research (Chicago, Ill.) (15.03.2021)
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Journal Article
Extendable blocking probe in reverse transcription for analysis of RNA variants with superior selectivity
Ho, Tho H, Dang, Kien X, Lintula, Susanna, Hotakainen, Kristina, Feng, Lin, Olkkonen, Vesa M, Verschuren, Emmy W, Tenkanen, Tuomas, Haglund, Caj, Kolho, Kaija-Leena, Stenman, Ulf-Hakan, Stenman, Jakob
Published in Nucleic acids research (01.01.2015)
Published in Nucleic acids research (01.01.2015)
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Journal Article
Receptor Tyrosine Kinase Signaling Networks Define Sensitivity to ERBB Inhibition and Stratify Kras -Mutant Lung Cancers
Talwelkar, Sarang S, Nagaraj, Ashwini S, Devlin, Jennifer R, Hemmes, Annabrita, Potdar, Swapnil, Kiss, Elina A, Saharinen, Pipsa, Salmenkivi, Kaisa, Mäyränpää, Mikko I, Wennerberg, Krister, Verschuren, Emmy W
Published in Molecular cancer therapeutics (01.10.2019)
Published in Molecular cancer therapeutics (01.10.2019)
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