Targeted selection of HIV-specific antibody mutations by engineering B cell maturation
Saunders, Kevin O, Wiehe, Kevin, Tian, Ming, Acharya, Priyamvada, Bradley, Todd, Alam, S Munir, Go, Eden P, Scearce, Richard, Sutherland, Laura, Henderson, Rory, Hsu, Allen L, Borgnia, Mario J, Chen, Haiyan, Lu, Xiaozhi, Wu, Nelson R, Watts, Brian, Jiang, Chuancang, Easterhoff, David, Cheng, Hwei-Ling, McGovern, Kelly, Waddicor, Peyton, Chapdelaine-Williams, Aimee, Eaton, Amanda, Zhang, Jinsong, Rountree, Wes, Verkoczy, Laurent, Tomai, Mark, Lewis, Mark G, Desaire, Heather R, Edwards, Robert J, Cain, Derek W, Bonsignori, Mattia, Montefiori, David, Alt, Frederick W, Haynes, Barton F
Published in Science (American Association for the Advancement of Science) (06.12.2019)
Published in Science (American Association for the Advancement of Science) (06.12.2019)
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SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts
Tasakis, Rafail Nikolaos, Samaras, Georgios, Jamison, Anna, Lee, Michelle, Paulus, Alexandra, Whitehouse, Gabrielle, Verkoczy, Laurent, Papavasiliou, F. Nina, Diaz, Marilyn
Published in PloS one (23.07.2021)
Published in PloS one (23.07.2021)
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Immune checkpoint modulation enhances HIV-1 antibody induction
Bradley, Todd, Kuraoka, Masayuki, Yeh, Chen-Hao, Tian, Ming, Chen, Huan, Cain, Derek W., Chen, Xuejun, Cheng, Cheng, Ellebedy, Ali H., Parks, Robert, Barr, Maggie, Sutherland, Laura L., Scearce, Richard M., Bowman, Cindy M., Bouton-Verville, Hilary, Santra, Sampa, Wiehe, Kevin, Lewis, Mark G., Ogbe, Ane, Borrow, Persephone, Montefiori, David, Bonsignori, Mattia, Anthony Moody, M., Verkoczy, Laurent, Saunders, Kevin O., Ahmed, Rafi, Mascola, John R., Kelsoe, Garnett, Alt, Frederick W., Haynes, Barton F.
Published in Nature communications (19.02.2020)
Published in Nature communications (19.02.2020)
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BCR and Endosomal TLR Signals Synergize to Increase AID Expression and Establish Central B Cell Tolerance
Kuraoka, Masayuki, Snowden, Pilar B., Nojima, Takuya, Verkoczy, Laurent, Haynes, Barton F., Kitamura, Daisuke, Kelsoe, Garnett
Published in Cell reports (Cambridge) (14.02.2017)
Published in Cell reports (Cambridge) (14.02.2017)
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Autoreactivity and broad neutralization of antibodies against HIV-1 are governed by distinct mutations: Implications for vaccine design strategies
Li, Xiaojun, Liao, Dongmei, Li, Zhengyang, Li, Jixi, Diaz, Marilyn, Verkoczy, Laurent, Gao, Feng
Published in Frontiers in immunology (18.11.2022)
Published in Frontiers in immunology (18.11.2022)
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Autoreactivity in an HIV-1 broadly reactive neutralizing antibody variable region heavy chain induces immunologic tolerance
Verkoczy, Laurent, Diaz, Marilyn, Holl, T. Matt, Ouyang, Ying-Bin, Bouton-Verville, Hilary, Alam, S. Munir, Liao, Hua-Xin, Kelsoe, Garnett, Haynes, Barton F
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (05.01.2010)
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Initiation of HIV neutralizing B cell lineages with sequential envelope immunizations
Williams, Wilton B., Zhang, Jinsong, Jiang, Chuancang, Nicely, Nathan I., Fera, Daniela, Luo, Kan, Moody, M. Anthony, Liao, Hua-Xin, Alam, S. Munir, Kepler, Thomas B., Ramesh, Akshaya, Wiehe, Kevin, Holland, James A., Bradley, Todd, Vandergrift, Nathan, Saunders, Kevin O., Parks, Robert, Foulger, Andrew, Xia, Shi-Mao, Bonsignori, Mattia, Montefiori, David C., Louder, Mark, Eaton, Amanda, Santra, Sampa, Scearce, Richard, Sutherland, Laura, Newman, Amanda, Bouton-Verville, Hilary, Bowman, Cindy, Bomze, Howard, Gao, Feng, Marshall, Dawn J., Whitesides, John F., Nie, Xiaoyan, Kelsoe, Garnett, Reed, Steven G., Fox, Christopher B., Clary, Kim, Koutsoukos, Marguerite, Franco, David, Mascola, John R., Harrison, Stephen C., Haynes, Barton F., Verkoczy, Laurent
Published in Nature communications (23.11.2017)
Published in Nature communications (23.11.2017)
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Engineering well-expressed, V2-immunofocusing HIV-1 envelope glycoprotein membrane trimers for use in heterologous prime-boost vaccine regimens
Crooks, Emma T, Almanza, Francisco, D'Addabbo, Alessio, Duggan, Erika, Zhang, Jinsong, Wagh, Kshitij, Mou, Huihui, Allen, Joel D, Thomas, Alyssa, Osawa, Keiko, Korber, Bette T, Tsybovsky, Yaroslav, Cale, Evan, Nolan, John, Crispin, Max, Verkoczy, Laurent K, Binley, James M
Published in PLoS pathogens (22.10.2021)
Published in PLoS pathogens (22.10.2021)
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Initiation of immune tolerance-controlled HIV gp41 neutralizing B cell lineages
Zhang, Ruijun, Verkoczy, Laurent, Wiehe, Kevin, Munir Alam, S, Nicely, Nathan I, Santra, Sampa, Bradley, Todd, Pemble, 4th, Charles W, Zhang, Jinsong, Gao, Feng, Montefiori, David C, Bouton-Verville, Hilary, Kelsoe, Garnett, Larimore, Kevin, Greenberg, Phillip D, Parks, Robert, Foulger, Andrew, Peel, Jessica N, Luo, Kan, Lu, Xiaozhi, Trama, Ashley M, Vandergrift, Nathan, Tomaras, Georgia D, Kepler, Thomas B, Moody, M Anthony, Liao, Hua-Xin, Haynes, Barton F
Published in Science translational medicine (27.04.2016)
Published in Science translational medicine (27.04.2016)
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The Chimpanzee SIV Envelope Trimer: Structure and Deployment as an HIV Vaccine Template
Andrabi, Raiees, Pallesen, Jesper, Allen, Joel D., Song, Ge, Zhang, Jinsong, de Val, Natalia, Gegg, Gavin, Porter, Katelyn, Su, Ching-Yao, Pauthner, Matthias, Newman, Amanda, Bouton-Verville, Hilary, Garces, Fernando, Wilson, Ian A., Crispin, Max, Hahn, Beatrice H., Haynes, Barton F., Verkoczy, Laurent, Ward, Andrew B., Burton, Dennis R.
Published in Cell reports (Cambridge) (21.05.2019)
Published in Cell reports (Cambridge) (21.05.2019)
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An autoreactive antibody from an SLE/HIV-1 individual broadly neutralizes HIV-1
Bonsignori, Mattia, Wiehe, Kevin, Grimm, Sebastian K, Lynch, Rebecca, Yang, Guang, Kozink, Daniel M, Perrin, Florence, Cooper, Abby J, Hwang, Kwan-Ki, Chen, Xi, Liu, Mengfei, McKee, Krisha, Parks, Robert J, Eudailey, Joshua, Wang, Minyue, Clowse, Megan, Criscione-Schreiber, Lisa G, Moody, M Anthony, Ackerman, Margaret E, Boyd, Scott D, Gao, Feng, Kelsoe, Garnett, Verkoczy, Laurent, Tomaras, Georgia D, Liao, Hua-Xin, Kepler, Thomas B, Montefiori, David C, Mascola, John R, Haynes, Barton F
Published in The Journal of clinical investigation (01.04.2014)
Published in The Journal of clinical investigation (01.04.2014)
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Redemption of autoreactive B cells
Haynes, Barton F., Verkoczy, Laurent, Kelsoe, Garnett
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (24.06.2014)
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Progress in HIV-1 vaccine development
Haynes, Barton F., MD, Moody, M. Anthony, MD, Alam, Munir, PhD, Bonsignori, Mattia, MD, Verkoczy, Laurent, PhD, Ferrari, Guido, MD, Gao, Feng, MD, Tomaras, Georgia D., PhD, Liao, Hua-Xin, MD, PhD, Kelsoe, Garnett, DSc
Published in Journal of allergy and clinical immunology (01.07.2014)
Published in Journal of allergy and clinical immunology (01.07.2014)
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A Germline-Targeting Chimpanzee SIV Envelope Glycoprotein Elicits a New Class of V2-Apex Directed Cross-Neutralizing Antibodies
Bibollet-Ruche, Frederic, Russell, Ronnie M, Ding, Wenge, Liu, Weimin, Li, Yingying, Wagh, Kshitij, Wrapp, Daniel, Habib, Rumi, Skelly, Ashwin N, Roark, Ryan S, Sherrill-Mix, Scott, Wang, Shuyi, Rando, Juliette, Lindemuth, Emily, Cruickshank, Kendra, Park, Younghoon, Baum, Rachel, Carey, John W, Connell, Andrew Jesse, Li, Hui, Giorgi, Elena E, Song, Ge S, Ding, Shilei, Finzi, Andrés, Newman, Amanda, Hernandez, Giovanna E, Machiele, Emily, Cain, Derek W, Mansouri, Katayoun, Lewis, Mark G, Montefiori, David C, Wiehe, Kevin J, Alam, S Munir, Teng, I-Ting, Kwong, Peter D, Andrabi, Raiees, Verkoczy, Laurent, Burton, Dennis R, Korber, Bette T, Saunders, Kevin O, Haynes, Barton F, Edwards, Robert J, Shaw, George M, Hahn, Beatrice H
Published in mBio (28.02.2023)
Published in mBio (28.02.2023)
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Immune perturbations in HIV-1-infected individuals who make broadly neutralizing antibodies
Moody, M Anthony, Pedroza-Pacheco, Isabela, Vandergrift, Nathan A, Chui, Cecilia, Lloyd, Krissey E, Parks, Robert, Soderberg, Kelly A, Ogbe, Ane T, Cohen, Myron S, Liao, Hua-Xin, Gao, Feng, McMichael, Andrew J, Montefiori, David C, Verkoczy, Laurent, Kelsoe, Garnett, Huang, Jinghe, Shea, Patrick R, Connors, Mark, Borrow, Persephone, Haynes, Barton F
Published in Science immunology (29.07.2016)
Published in Science immunology (29.07.2016)
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Differential Reactivity of Germ Line Allelic Variants of a Broadly Neutralizing HIV-1 Antibody to a gp41 Fusion Intermediate Conformation
MUNIR ALAM, S, LIAO, Hua-Xin, NICELY, Nathan, TOMARAS, Georgia D, KELSOE, Garnett, BING CHEN, KEPLER, Thomas B, HAYNES, Barton F, MOSES DENNISON, S, JAEGER, Frederick, PARKS, Robert, ANASTI, Kara, FOULGER, Andrew, DONATHAN, Michele, LUCAS, Judith, VERKOCZY, Laurent
Published in Journal of Virology (01.11.2011)
Published in Journal of Virology (01.11.2011)
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Immunodominance of Antibody Recognition of the HIV Envelope V2 Region in Ig-Humanized Mice
Wiehe, Kevin, Nicely, Nathan I, Lockwood, Bradley, Kuraoka, Masayuki, Anasti, Kara, Arora, Sabrina, Bowman, Cindy M, Stolarchuk, Christina, Parks, Robert, Lloyd, Krissey E, Xia, Shi-Mao, Duffy, Ryan, Shen, Xiaoying, Kyratsous, Christos A, Macdonald, Lynn E, Murphy, Andrew J, Scearce, Richard M, Moody, M Anthony, Alam, S Munir, Verkoczy, Laurent, Tomaras, Georgia D, Kelsoe, Garnett, Haynes, Barton F
Published in The Journal of immunology (1950) (01.02.2017)
Published in The Journal of immunology (1950) (01.02.2017)
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Basal B Cell Receptor-Directed Phosphatidylinositol 3-Kinase Signaling Turns Off RAGs and Promotes B Cell-Positive Selection
Verkoczy, Laurent, Duong, Bao, Skog, Patrick, Ait-Azzouzene, Djemel, Puri, Kamal, Vela, Jose Luis, Nemazee, David
Published in Journal of Immunology (15.05.2007)
Published in Journal of Immunology (15.05.2007)
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