MutationalPatterns: the one stop shop for the analysis of mutational processes
Manders, Freek, Brandsma, Arianne M, de Kanter, Jurrian, Verheul, Mark, Oka, Rurika, van Roosmalen, Markus J, van der Roest, Bastiaan, van Hoeck, Arne, Cuppen, Edwin, van Boxtel, Ruben
Published in BMC genomics (15.02.2022)
Published in BMC genomics (15.02.2022)
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Journal Article
Somatic Mutations Reveal Lineage Relationships and Age-Related Mutagenesis in Human Hematopoiesis
Osorio, Fernando G., Rosendahl Huber, Axel, Oka, Rurika, Verheul, Mark, Patel, Sachin H., Hasaart, Karlijn, de la Fonteijne, Lisanne, Varela, Ignacio, Camargo, Fernando D., van Boxtel, Ruben
Published in Cell reports (Cambridge) (27.11.2018)
Published in Cell reports (Cambridge) (27.11.2018)
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Journal Article
Selective pressures of platinum compounds shape the evolution of therapy-related myeloid neoplasms
Bertrums, Eline J. M., de Kanter, Jurrian K., Derks, Lucca L. M., Verheul, Mark, Trabut, Laurianne, van Roosmalen, Markus J., Hasle, Henrik, Antoniou, Evangelia, Reinhardt, Dirk, Dworzak, Michael N., Mühlegger, Nora, van den Heuvel-Eibrink, Marry M., Zwaan, C. Michel, Goemans, Bianca F., van Boxtel, Ruben
Published in Nature communications (17.07.2024)
Published in Nature communications (17.07.2024)
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Journal Article
Mutation accumulation and developmental lineages in normal and Down syndrome human fetal haematopoiesis
Hasaart, Karlijn A. L., Manders, Freek, van der Hoorn, Marie-Louise, Verheul, Mark, Poplonski, Tomasz, Kuijk, Ewart, de Sousa Lopes, Susana M. Chuva, van Boxtel, Ruben
Published in Scientific reports (31.07.2020)
Published in Scientific reports (31.07.2020)
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Journal Article
Distribution and functional impact of DNA copy number variation in the rat
Hubner, Norbert, Aitman, Timothy, Cook, Stuart, Jacob, Howard, Cuppen, Edwin, Pravenec, Michal, Saar, Kathrin, Verheul, Mark, van Heesch, Sebastiaan A A C, Adamovic, Tatjana, Shull, James D, Guryev, Victor
Published in Nature genetics (01.05.2008)
Published in Nature genetics (01.05.2008)
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Journal Article
Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
Berezikov, Eugene, van Tetering, Geert, Verheul, Mark, van de Belt, Jose, van Laake, Linda, Vos, Joost, Verloop, Robert, van de Wetering, Marc, Guryev, Victor, Takada, Shuji, van Zonneveld, Anton Jan, Mano, Hiroyuki, Plasterk, Ronald, Cuppen, Edwin
Published in Genome Research (01.10.2006)
Published in Genome Research (01.10.2006)
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Journal Article
A functional screen identifies specific microRNAs capable of inhibiting human melanoma cell viability
Poell, Jos B, van Haastert, Rick J, de Gunst, Thijs, Schultz, Iman J, Gommans, Willemijn M, Verheul, Mark, Cerisoli, Francesco, van Puijenbroek, Andre A F L, van Noort, Paula I, Prevost, Gregoire P, Schaapveld, Roel Q J, Cuppen, Edwin
Published in PloS one (22.08.2012)
Published in PloS one (22.08.2012)
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Journal Article
Human induced pluripotent stem cells display a similar mutation burden as embryonic pluripotent cells in vivo
Hasaart, Karlijn A.L., Manders, Freek, Ubels, Joske, Verheul, Mark, van Roosmalen, Markus J., Groenen, Niels M., Oka, Rurika, Kuijk, Ewart, Lopes, Susana M. Chuva de Sousa, Boxtel, Ruben van
Published in iScience (18.02.2022)
Published in iScience (18.02.2022)
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Journal Article
Generation of gene knockouts and mutant models in the laboratory rat by ENU-driven target-selected mutagenesis
Smits, Bart M G, Mudde, Josine B, van de Belt, Jose, Verheul, Mark, Olivier, Jocelien, Homberg, Judith, Guryev, Victor, Cools, Alexander R, Ellenbroek, Bart A, Plasterk, Ronald H A, Cuppen, Edwin
Published in Pharmacogenetics and genomics (01.03.2006)
Published in Pharmacogenetics and genomics (01.03.2006)
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Journal Article
A genome-wide SNP panel for mapping and association studies in the rat
Nijman, Isaäc J, Kuipers, Sylvia, Verheul, Mark, Guryev, Victor, Cuppen, Edwin
Published in BMC genomics (25.02.2008)
Published in BMC genomics (25.02.2008)
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Journal Article
Haplotype block structure is conserved across mammals
Guryev, Victor, Smits, Bart M G, van de Belt, Jose, Verheul, Mark, Hubner, Norbert, Cuppen, Edwin
Published in PLoS genetics (01.07.2006)
Published in PLoS genetics (01.07.2006)
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Journal Article
Correction: A Functional Screen Identifies Specific MicroRNAs Capable of Inhibiting Human Melanoma Cell Viability
Poell, Jos B, van Haastert, Rick J, de Gunst, Thijs, Schultz, Iman J, Gommans, Willemijn M, Verheul, Mark, Cerisoli, Francesco, van Puijenbroek, Andre A F L, van Noort, Paula I, Prevost, Gregoire P, Schaapveld, Roel Q J, Cuppen, Edwin
Published in PloS one (2013)
Published in PloS one (2013)
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Journal Article
Antiviral treatment causes a unique mutational signature in cancers of transplantation recipients
de Kanter, Jurrian K., Peci, Flavia, Bertrums, Eline, Rosendahl Huber, Axel, van Leeuwen, Anaïs, van Roosmalen, Markus J., Manders, Freek, Verheul, Mark, Oka, Rurika, Brandsma, Arianne M., Bierings, Marc, Belderbos, Mirjam, van Boxtel, Ruben
Published in Cell stem cell (07.10.2021)
Published in Cell stem cell (07.10.2021)
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Journal Article
Improved detection of colibactin-induced mutations by genotoxic E. coli in organoids and colorectal cancer
Rosendahl Huber, Axel, Pleguezuelos-Manzano, Cayetano, Puschhof, Jens, Ubels, Joske, Boot, Charelle, Saftien, Aurelia, Verheul, Mark, Trabut, Laurianne T., Groenen, Niels, van Roosmalen, Markus, Ouyang, Kyanna S., Wood, Henry, Quirke, Phil, Meijer, Gerrit, Cuppen, Edwin, Clevers, Hans, van Boxtel, Ruben
Published in Cancer cell (11.03.2024)
Published in Cancer cell (11.03.2024)
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Journal Article
Retrospective Lineage Tracing of Pediatric Acute Myeloid Leukemia Using Single-Cell Whole Genome Sequencing
Bertrums, Eline J.M., Middelkamp, Sjors, van der Werf, Inge M., Manders, Freek, Brandsma, Arianne M., Groenen, Niels M., Verheul, Mark, van Roosmalen, Markus J., Zwaan, C. Michel, van den Heuvel-Eibrink, Marry M., Goemans, Bianca F., Van Boxtel, Ruben
Published in Blood (15.11.2022)
Published in Blood (15.11.2022)
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Journal Article
Elevated Mutational Age in Blood of Children Treated for Cancer Contributes to Therapy-Related Myeloid Neoplasms
Bertrums, Eline J M, Rosendahl Huber, Axel K M, de Kanter, Jurrian K, Brandsma, Arianne M, van Leeuwen, Anaïs J C N, Verheul, Mark, van den Heuvel-Eibrink, Marry M, Oka, Rurika, van Roosmalen, Markus J, de Groot-Kruseman, Hester A, Zwaan, C Michel, Goemans, Bianca F, van Boxtel, Ruben
Published in Cancer discovery (05.08.2022)
Published in Cancer discovery (05.08.2022)
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Journal Article
Systemic miRNA-7 delivery inhibits tumor angiogenesis and growth in murine xenograft glioblastoma
Babae, Negar, Bourajjaj, Meriem, Liu, Yijia, Van Beijnum, Judy R, Cerisoli, Francesco, Scaria, Puthupparampil V, Verheul, Mark, Van Berkel, Maaike P, Pieters, Ebel H E, Van Haastert, Rick J, Yousefi, Afrouz, Mastrobattista, Enrico, Storm, Gert, Berezikov, Eugene, Cuppen, Edwin, Woodle, Martin, Schaapveld, Roel Q J, Prevost, Gregoire P, Griffioen, Arjan W, Van Noort, Paula I, Schiffelers, Raymond M
Published in Oncotarget (30.08.2014)
Published in Oncotarget (30.08.2014)
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Journal Article
Mutation signatures of pediatric acute myeloid leukemia and normal blood progenitors associated with differential patient outcomes
Brandsma, Arianne M, Bertrums, Eline J M, van Roosmalen, Markus J, Hofman, Damon A, Oka, Rurika, Verheul, Mark, Manders, Freek, Ubels, Joske, Belderbos, Mirjam E, van Boxtel, Ruben
Published in Blood cancer discovery (01.09.2021)
Published in Blood cancer discovery (01.09.2021)
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Journal Article
Cloning and expression of new microRNAs from zebrafish
Kloosterman, Wigard P., Steiner, Florian A., Berezikov, Eugene, de Bruijn, Ewart, van de Belt, Jose, Verheul, Mark, Cuppen, Edwin, Plasterk, Ronald H.A.
Published in Nucleic acids research (01.01.2006)
Published in Nucleic acids research (01.01.2006)
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Journal Article