Long non-coding RNA Gm15441 attenuates hepatic inflammasome activation in response to PPARA agonism and fasting
Brocker, Chad N., Kim, Donghwan, Melia, Tisha, Karri, Kritika, Velenosi, Thomas J., Takahashi, Shogo, Aibara, Daisuke, Bonzo, Jessica A., Levi, Moshe, Waxman, David J., Gonzalez, Frank J.
Published in Nature communications (17.11.2020)
Published in Nature communications (17.11.2020)
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Journal Article
Metabolic products of the intestinal microbiome and extremes of atherosclerosis
Bogiatzi, Chrysi, Gloor, Gregory, Allen-Vercoe, Emma, Reid, Gregor, Wong, Ruth G., Urquhart, Bradley L., Dinculescu, Vincent, Ruetz, Kelsey N., Velenosi, Thomas J., Pignanelli, Michael, Spence, J. David
Published in Atherosclerosis (01.06.2018)
Published in Atherosclerosis (01.06.2018)
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Journal Article
Metabolomics for the identification of early biomarkers of nephrotoxicity in a mouse model of cisplatin-induced acute kidney injury
Lim, Yong Jin, Tonial, Nicholas C., Hartjes, Emily D., Haig, Aaron, Velenosi, Thomas J., Urquhart, Bradley L.
Published in Biomedicine & pharmacotherapy (01.07.2023)
Published in Biomedicine & pharmacotherapy (01.07.2023)
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Journal Article
Mediterranean Diet Score: Associations with Metabolic Products of the Intestinal Microbiome, Carotid Plaque Burden, and Renal Function
Pignanelli, Michael, Just, Caroline, Bogiatzi, Chrysi, Dinculescu, Vincent, Gloor, Gregory B, Allen-Vercoe, Emma, Reid, Gregor, Urquhart, Bradley L, Ruetz, Kelsey N, Velenosi, Thomas J, Spence, J David
Published in Nutrients (16.06.2018)
Published in Nutrients (16.06.2018)
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Journal Article
Hepatocyte-specific CCAAT/enhancer binding protein α restricts liver fibrosis progression
Yan, Tingting, Yan, Nana, Xia, Yangliu, Sawaswong, Vorthon, Zhu, Xinxin, Dias, Henrique Bregolin, Aibara, Daisuke, Takahashi, Shogo, Hamada, Keisuke, Saito, Yoshifumi, Li, Guangming, Liu, Hui, Yan, Hualong, Velenosi, Thomas J, Krausz, Kristopher W, Huang, Jing, Kimura, Shioko, Rotman, Yaron, Qu, Aijuan, Hao, Haiping, Gonzalez, Frank J
Published in The Journal of clinical investigation (01.04.2024)
Published in The Journal of clinical investigation (01.04.2024)
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Journal Article
Effect of CKD and Dialysis Modality on Exposure to Drugs Cleared by Nonrenal Mechanisms
Thomson, Benjamin K.A., MSc, MD, Nolin, Thomas D., PharmD, PhD, Velenosi, Thomas J., BMSc, Feere, David A., BMSc, MSc, Knauer, Michael J., BMSc, PhD, Asher, Linda J., RN, House, Andrew A., MSc, MD, Urquhart, Bradley L., PhD
Published in American journal of kidney diseases (01.04.2015)
Published in American journal of kidney diseases (01.04.2015)
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Journal Article
Clenbuterol exerts antidiabetic activity through metabolic reprogramming of skeletal muscle cells
Meister, Jaroslawna, Bone, Derek B. J., Knudsen, Jonas R., Barella, Luiz F., Velenosi, Thomas J., Akhmedov, Dmitry, Lee, Regina J., Cohen, Amanda H., Gavrilova, Oksana, Cui, Yinghong, Karsenty, Gerard, Chen, Min, Weinstein, Lee S., Kleinert, Maximilian, Berdeaux, Rebecca, Jensen, Thomas E., Richter, Erik A., Wess, Jürgen
Published in Nature communications (10.01.2022)
Published in Nature communications (10.01.2022)
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Journal Article
Untargeted metabolomics reveals N, N, N-trimethyl-L-alanyl-L-proline betaine (TMAP) as a novel biomarker of kidney function
Velenosi, Thomas J., Thomson, Benjamin K. A., Tonial, Nicholas C., RaoPeters, Adrien A. E., Mio, Megan A., Lajoie, Gilles A., Garg, Amit X., House, Andrew A., Urquhart, Bradley L.
Published in Scientific reports (02.05.2019)
Published in Scientific reports (02.05.2019)
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Journal Article
Moderate Renal Impairment and Toxic Metabolites Produced by the Intestinal Microbiome: Dietary Implications
Pignanelli, Michael, Bogiatzi, Chrysi, Gloor, Gregory, Allen-Vercoe, Emma, Reid, Gregor, Urquhart, Bradley L, Ruetz, Kelsey N, Velenosi, Thomas J, Spence, J David
Published in Journal of renal nutrition (01.01.2019)
Published in Journal of renal nutrition (01.01.2019)
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Journal Article
Postprandial Plasma Lipidomics Reveal Specific Alteration of Hepatic-derived Diacylglycerols in Nonalcoholic Fatty Liver Disease
Velenosi, Thomas J., Ben-Yakov, Gil, Podszun, Maren C., Hercun, Julian, Etzion, Ohad, Yang, Shanna, Nadal, Cathy, Haynes-Williams, Vanessa, Huang, Wen-Chun A., González-Hódar, Lila, Brychta, Robert J., Takahashi, Shogo, Akkaraju, Vikas, Krausz, Kristopher W., Walter, Mary, Cai, Hongyi, Walter, Peter J., Muniyappa, Ranganath, Chen, Kong Y., Gonzalez, Frank J., Rotman, Yaron
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2022)
Published in Gastroenterology (New York, N.Y. 1943) (01.06.2022)
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Journal Article
Decreased nuclear receptor activity and epigenetic modulation associates with down-regulation of hepatic drug-metabolizing enzymes in chronic kidney disease
Velenosi, Thomas J, Feere, David A, Sohi, Gurjeev, Hardy, Daniel B, Urquhart, Bradley L
Published in The FASEB journal (01.12.2014)
Published in The FASEB journal (01.12.2014)
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Journal Article
Silencing IDO in dendritic cells: A novel approach to enhance cancer immunotherapy in a murine breast cancer model
Zheng, Xiufen, Koropatnick, James, Chen, Di, Velenosi, Thomas, Ling, Hong, Zhang, Xusheng, Jiang, Nan, Navarro, Benjamin, Ichim, Thomas E., Urquhart, Bradley, Min, Weiping
Published in International journal of cancer (15.02.2013)
Published in International journal of cancer (15.02.2013)
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Journal Article
Untargeted plasma and tissue metabolomics in rats with chronic kidney disease given AST-120
Velenosi, Thomas J., Hennop, Anzel, Feere, David A., Tieu, Alvin, Kucey, Andrew S., Kyriacou, Polydoros, McCuaig, Laura E., Nevison, Stephanie E., Kerr, Michael A., Urquhart, Bradley L.
Published in Scientific reports (02.03.2016)
Published in Scientific reports (02.03.2016)
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Journal Article
Extrahepatic PPARα modulates fatty acid oxidation and attenuates fasting-induced hepatosteatosis in mice
Brocker, Chad N., Patel, Daxesh P., Velenosi, Thomas J., Kim, Donghwan, Yan, Tingting, Yue, Jiang, Li, Guolin, Krausz, Kristopher W., Gonzalez, Frank J.
Published in Journal of lipid research (01.11.2018)
Published in Journal of lipid research (01.11.2018)
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Journal Article
Role of Farnesoid X Receptor and Bile Acids in Hepatic Tumor Development
Takahashi, Shogo, Tanaka, Naoki, Fukami, Tatsuki, Xie, Cen, Yagai, Tomoki, Kim, Donghwan, Velenosi, Thomas J., Yan, Tingting, Krausz, Kristopher W., Levi, Moshe, Gonzalez, Frank J.
Published in Hepatology communications (01.12.2018)
Published in Hepatology communications (01.12.2018)
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Journal Article
Metabolomic Response of Skeletal Muscle to Aerobic Exercise Training in Insulin Resistant Type 1 Diabetic Rats
Dotzert, Michelle S., Murray, Michael R., McDonald, Matthew W., Olver, T. Dylan, Velenosi, Thomas J., Hennop, Anzel, Noble, Earl G., Urquhart, Brad L., Melling, C. W. James
Published in Scientific reports (20.05.2016)
Published in Scientific reports (20.05.2016)
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Journal Article
Pharmacometabolomics reveals urinary diacetylspermine as a biomarker of doxorubicin effectiveness in triple negative breast cancer
Velenosi, Thomas J., Krausz, Kristopher W., Hamada, Keisuke, Dorsey, Tiffany H., Ambs, Stefan, Takahashi, Shogo, Gonzalez, Frank J.
Published in NPJ precision oncology (07.10.2022)
Published in NPJ precision oncology (07.10.2022)
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Journal Article