The BRAF Pseudogene Functions as a Competitive Endogenous RNA and Induces Lymphoma In Vivo
Karreth, Florian A., Reschke, Markus, Ruocco, Anna, Ng, Christopher, Chapuy, Bjoern, Léopold, Valentine, Sjoberg, Marcela, Keane, Thomas M., Verma, Akanksha, Ala, Ugo, Tay, Yvonne, Wu, David, Seitzer, Nina, Velasco-Herrera, Martin Del Castillo, Bothmer, Anne, Fung, Jacqueline, Langellotto, Fernanda, Rodig, Scott J., Elemento, Olivier, Shipp, Margaret A., Adams, David J., Chiarle, Roberto, Pandolfi, Pier Paolo
Published in Cell (09.04.2015)
Published in Cell (09.04.2015)
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Journal Article
Off-target assessment of CRISPR-Cas9 guiding RNAs in human iPS and mouse ES cells
Tan, E-Pien, Li, Yilong, Del Castillo Velasco-Herrera, Martin, Yusa, Kosuke, Bradley, Allan
Published in Genesis (New York, N.Y. : 2000) (01.02.2015)
Published in Genesis (New York, N.Y. : 2000) (01.02.2015)
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Journal Article
Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors
Young, Matthew D, Mitchell, Thomas J, Vieira Braga, Felipe A, Tran, Maxine G B, Stewart, Benjamin J, Ferdinand, John R, Collord, Grace, Botting, Rachel A, Popescu, Dorin-Mirel, Loudon, Kevin W, Vento-Tormo, Roser, Stephenson, Emily, Cagan, Alex, Farndon, Sarah J, Del Castillo Velasco-Herrera, Martin, Guzzo, Charlotte, Richoz, Nathan, Mamanova, Lira, Aho, Tevita, Armitage, James N, Riddick, Antony C P, Mushtaq, Imran, Farrell, Stephen, Rampling, Dyanne, Nicholson, James, Filby, Andrew, Burge, Johanna, Lisgo, Steven, Maxwell, Patrick H, Lindsay, Susan, Warren, Anne Y, Stewart, Grant D, Sebire, Neil, Coleman, Nicholas, Haniffa, Muzlifah, Teichmann, Sarah A, Clatworthy, Menna, Behjati, Sam
Published in Science (American Association for the Advancement of Science) (10.08.2018)
Published in Science (American Association for the Advancement of Science) (10.08.2018)
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Journal Article
Comparative genomics reveals that loss of lunatic fringe (LFNG) promotes melanoma metastasis
Del Castillo Velasco‐Herrera, Martin, Weyden, Louise, Nsengimana, Jeremie, Speak, Anneliese O., Sjöberg, Marcela K., Bishop, David Timothy, Jönsson, Göran, Newton‐Bishop, Julia, Adams, David J.
Published in Molecular oncology (01.02.2018)
Published in Molecular oncology (01.02.2018)
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Journal Article
Combinatorial CRISPR screen identifies fitness effects of gene paralogues
Thompson, Nicola A., Ranzani, Marco, van der Weyden, Louise, Iyer, Vivek, Offord, Victoria, Droop, Alastair, Behan, Fiona, Gonçalves, Emanuel, Speak, Anneliese, Iorio, Francesco, Hewinson, James, Harle, Victoria, Robertson, Holly, Anderson, Elizabeth, Fu, Beiyuan, Yang, Fengtang, Zagnoli-Vieira, Guido, Chapman, Phil, Del Castillo Velasco-Herrera, Martin, Garnett, Mathew J., Jackson, Stephen P., Adams, David J.
Published in Nature communications (26.02.2021)
Published in Nature communications (26.02.2021)
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Journal Article
Recurrent intragenic rearrangements of EGFR and BRAF in soft tissue tumors of infants
Wegert, Jenny, Vokuhl, Christian, Collord, Grace, Del Castillo Velasco-Herrera, Martin, Farndon, Sarah J., Guzzo, Charlotte, Jorgensen, Mette, Anderson, John, Slater, Olga, Duncan, Catriona, Bausenwein, Sabrina, Streitenberger, Heike, Ziegler, Barbara, Furtwängler, Rhoikos, Graf, Norbert, Stratton, Michael R., Campbell, Peter J., Jones, David TW, Koelsche, Christian, Pfister, Stefan M., Mifsud, William, Sebire, Neil, Sparber-Sauer, Monika, Koscielniak, Ewa, Rosenwald, Andreas, Gessler, Manfred, Behjati, Sam
Published in Nature communications (18.06.2018)
Published in Nature communications (18.06.2018)
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Journal Article
Genomic Determinants of Protein Abundance Variation in Colorectal Cancer Cells
Roumeliotis, Theodoros I., Williams, Steven P., Gonçalves, Emanuel, Alsinet, Clara, Del Castillo Velasco-Herrera, Martin, Aben, Nanne, Ghavidel, Fatemeh Zamanzad, Michaut, Magali, Schubert, Michael, Price, Stacey, Wright, James C., Yu, Lu, Yang, Mi, Dienstmann, Rodrigo, Guinney, Justin, Beltrao, Pedro, Brazma, Alvis, Pardo, Mercedes, Stegle, Oliver, Adams, David J., Wessels, Lodewyk, Saez-Rodriguez, Julio, McDermott, Ultan, Choudhary, Jyoti S.
Published in Cell reports (Cambridge) (29.08.2017)
Published in Cell reports (Cambridge) (29.08.2017)
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Journal Article
NFIL3 contributes to cytotoxic T lymphocyte-mediated killing
Douanne, Tiphaine, Strege, Katharina, Del Castillo Velasco-Herrera, Martin, Rochussen, Adam M, Adams, David J, Griffiths, Gillian M
Published in Open biology (28.02.2024)
Published in Open biology (28.02.2024)
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Journal Article
Spatiotemporal immune zonation of the human kidney
Stewart, Benjamin J, Ferdinand, John R, Young, Matthew D, Mitchell, Thomas J, Loudon, Kevin W, Riding, Alexandra M, Richoz, Nathan, Frazer, Gordon L, Staniforth, Joy U L, Vieira Braga, Felipe A, Botting, Rachel A, Popescu, Dorin-Mirel, Vento-Tormo, Roser, Stephenson, Emily, Cagan, Alex, Farndon, Sarah J, Polanski, Krzysztof, Efremova, Mirjana, Green, Kile, Del Castillo Velasco-Herrera, Martin, Guzzo, Charlotte, Collord, Grace, Mamanova, Lira, Aho, Tevita, Armitage, James N, Riddick, Antony C P, Mushtaq, Imran, Farrell, Stephen, Rampling, Dyanne, Nicholson, James, Filby, Andrew, Burge, Johanna, Lisgo, Steven, Lindsay, Susan, Bajenoff, Marc, Warren, Anne Y, Stewart, Grant D, Sebire, Neil, Coleman, Nicholas, Haniffa, Muzlifah, Teichmann, Sarah A, Behjati, Sam, Clatworthy, Menna R
Published in Science (American Association for the Advancement of Science) (27.09.2019)
Published in Science (American Association for the Advancement of Science) (27.09.2019)
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Journal Article
Single-cell sequencing reveals clonal expansions of pro-inflammatory synovial CD8 T cells expressing tissue-homing receptors in psoriatic arthritis
Penkava, Frank, Velasco-Herrera, Martin Del Castillo, Young, Matthew D., Yager, Nicole, Nwosu, Lilian N., Pratt, Arthur G., Lara, Alicia Lledo, Guzzo, Charlotte, Maroof, Ash, Mamanova, Lira, Cole, Suzanne, Efremova, Mirjana, Simone, Davide, Filer, Andrew, Brown, Chrysothemis C., Croxford, Andrew L., Isaacs, John D., Teichmann, Sarah, Bowness, Paul, Behjati, Sam, Hussein Al-Mossawi, M.
Published in Nature communications (21.09.2020)
Published in Nature communications (21.09.2020)
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Journal Article
Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations
Iovino, Mariangela, Agathou, Sylvia, González-Rueda, Ana, Del Castillo Velasco-Herrera, Martin, Borroni, Barbara, Alberici, Antonella, Lynch, Timothy, O'Dowd, Sean, Geti, Imbisaat, Gaffney, Daniel, Vallier, Ludovic, Paulsen, Ole, Káradóttir, Ragnhildur Thóra, Spillantini, Maria Grazia
Published in Brain (London, England : 1878) (01.11.2015)
Published in Brain (London, England : 1878) (01.11.2015)
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Journal Article
Predictive Immune-Checkpoint Blockade Classifiers Identify Tumors Responding to Inhibition of PD-1 and/or CTLA-4
Krijgsman, Oscar, Kemper, Kristel, Boshuizen, Julia, Vredevoogd, David W, Rozeman, Elisa A, Ibanez Molero, Sofia, de Bruijn, Beaunelle, Cornelissen-Steijger, Paulien, Shahrabi, Aida, Del Castillo Velasco-Herrera, Martin, Song, Ji-Ying, Ligtenberg, Maarten A, Kluin, Roelof J C, Kuilman, Thomas, Ross-Macdonald, Petra, Haanen, John B A G, Adams, David J, Blank, Christian U, Peeper, Daniel S
Published in Clinical cancer research (01.10.2021)
Published in Clinical cancer research (01.10.2021)
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Journal Article
Disruption of mouse Cenpj, a regulator of centriole biogenesis, phenocopies Seckel syndrome
McIntyre, Rebecca E, Lakshminarasimhan Chavali, Pavithra, Ismail, Ozama, Carragher, Damian M, Sanchez-Andrade, Gabriela, Forment, Josep V, Fu, Beiyuan, Del Castillo Velasco-Herrera, Martin, Edwards, Andrew, van der Weyden, Louise, Yang, Fengtang, Ramirez-Solis, Ramiro, Estabel, Jeanne, Gallagher, Ferdia A, Logan, Darren W, Arends, Mark J, Tsang, Stephen H, Mahajan, Vinit B, Scudamore, Cheryl L, White, Jacqueline K, Jackson, Stephen P, Gergely, Fanni, Adams, David J
Published in PLoS genetics (01.11.2012)
Published in PLoS genetics (01.11.2012)
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Journal Article
FIRRM/C1orf112 mediates resolution of homologous recombination intermediates in response to DNA interstrand crosslinks
Mazouzi, Abdelghani, Moser, Sarah C, Abascal, Federico, van den Broek, Bram, Del Castillo Velasco-Herrera, Martin, van der Heijden, Ingrid, Hekkelman, Maarten, Drenth, Anne Paulien, van der Burg, Eline, Kroese, Lona J, Jalink, Kees, Adams, David J, Jonkers, Jos, Brummelkamp, Thijn R
Published in Science advances (02.06.2023)
Published in Science advances (02.06.2023)
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Journal Article
Reconstructing and mining the B cell repertoire with ImmunediveRsity
Cortina-Ceballos, Bernardo, Godoy-Lozano, Elizabeth Ernestina, Sámano-Sánchez, Hugo, Aguilar-Salgado, Andrés, Velasco-Herrera, Martín Del Castillo, Vargas-Chávez, Carlos, Velázquez-Ramírez, Daniel, Romero, Guillermo, Moreno, José, Téllez-Sosa, Juan, Martínez-Barnetche, Jesús
Published in mAbs (04.05.2015)
Published in mAbs (04.05.2015)
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Journal Article
Revisiting olfactory receptors as putative drivers of cancer
Ranzani, Marco, Iyer, Vivek, Ibarra-Soria, Ximena, Del Castillo Velasco-Herrera, Martin, Garnett, Mathew, Logan, Darren, Adams, David J
Published in Wellcome open research (10.02.2017)
Published in Wellcome open research (10.02.2017)
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Journal Article
Genome-wide in vivo screen identifies novel host regulators of metastatic colonization
van der Weyden, Louise, Arends, Mark J., Campbell, Andrew D., Bald, Tobias, Wardle-Jones, Hannah, Griggs, Nicola, Velasco-Herrera, Martin Del Castillo, Tüting, Thomas, Sansom, Owen J., Karp, Natasha A., Clare, Simon, Gleeson, Diane, Ryder, Edward, Galli, Antonella, Tuck, Elizabeth, Cambridge, Emma L., Voet, Thierry, Macaulay, Iain C., Wong, Kim, Spiegel, Sarah, Speak, Anneliese O., Adams, David J.
Published in Nature (London) (12.01.2017)
Published in Nature (London) (12.01.2017)
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Journal Article
Comprehensive mutational profiling identifies new driver events in cutaneous leiomyosarcoma
van der Weyden, Louise, Del Castillo Velasco-Herrera, Martin, Cheema, Saamin, Wong, Kim, Boccacino, Jacqueline M, Offord, Victoria, Droop, Alastair, Jones, David R A, Vermes, Ian, Anderson, Elizabeth, Hardy, Claire, de Saint Aubain, Nicolas, Ferguson, Peter M, Clarke, Emily L, Merchant, William, Mogler, Carolin, Frew, Derek, Harms, Paul W, Monteagudo, Carlos, Billings, Steven D, Arends, Mark J, Ferreira, Ingrid, Brenn, Thomas, J Adams, David
Published in British journal of dermatology (1951) (11.10.2024)
Published in British journal of dermatology (1951) (11.10.2024)
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