A Unitary Anesthetic Binding Site at High Resolution
Vedula, L. Sangeetha, Brannigan, Grace, Economou, Nicoleta J., Xi, Jin, Hall, Michael A., Liu, Renyu, Rossi, Matthew J., Dailey, William P., Grasty, Kimberly C., Klein, Michael L., Eckenhoff, Roderic G., Loll, Patrick J.
Published in The Journal of biological chemistry (04.09.2009)
Published in The Journal of biological chemistry (04.09.2009)
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Journal Article
Recognition of anesthetic barbiturates by a protein binding site: a high resolution structural analysis
Oakley, Simon, Vedula, L Sangeetha, Bu, Weiming, Meng, Qing Cheng, Xi, Jin, Liu, Renyu, Eckenhoff, Roderic G, Loll, Patrick J
Published in PloS one (16.02.2012)
Published in PloS one (16.02.2012)
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Journal Article
Molecular Recognition of the Substrate Diphosphate Group Governs Product Diversity in Trichodiene Synthase Mutants
Vedula, L. Sangeetha, Rynkiewicz, Michael J, Pyun, Hyung-Jung, Coates, Robert M, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (26.04.2005)
Published in Biochemistry (Easton) (26.04.2005)
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Journal Article
Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization–Fragmentation Reaction Sequence
Harris, Golda G, Lombardi, Patrick M, Pemberton, Travis A, Matsui, Tsutomu, Weiss, Thomas M, Cole, Kathryn E, Köksal, Mustafa, Murphy, Frank V, Vedula, L. Sangeetha, Chou, Wayne K. W, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (08.12.2015)
Published in Biochemistry (Easton) (08.12.2015)
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Journal Article
Exploring biosynthetic diversity with trichodiene synthase
Vedula, L. Sangeetha, Zhao, Yuxin, Coates, Robert M., Koyama, Tanetoshi, Cane, David E., Christianson, David W.
Published in Archives of biochemistry and biophysics (15.10.2007)
Published in Archives of biochemistry and biophysics (15.10.2007)
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Journal Article
Role of Arginine-304 in the Diphosphate-Triggered Active Site Closure Mechanism of Trichodiene Synthase
Vedula, L. Sangeetha, Cane, David E, Christianson, David W
Published in Biochemistry (Easton) (27.09.2005)
Published in Biochemistry (Easton) (27.09.2005)
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Journal Article
Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with Alpha-Alpha Domain Architecture that Catalyzes a Unique Cyclization-Fragmentation Reaction Sequence
Harris, Golda G., Lombardi, Patrick M., Pemberton, Travis A., Matsui, Tsutomu, Weiss, Thomas M., Cole, Kathryn E., Köksal, Mustafa, Murphy, Frank V., Vedula, L. Sangeetha, Chou, Wayne K.W., Cane, David E., Christianson, David W.
Published in Biochemistry (Easton) (08.12.2015)
Published in Biochemistry (Easton) (08.12.2015)
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Journal Article
Structural Studies of Geosmin Synthase, a Bifunctional Sesquiterpene Synthase with αα Domain Architecture That Catalyzes a Unique Cyclization–Fragmentation Reaction Sequence
Harris, Golda G., Lombardi, Patrick M., Pemberton, Travis A., Matsui, Tsutomu, Weiss, Thomas M., Cole, Kathryn E., Köksal, Mustafa, Murphy, Frank V., Vedula, L. Sangeetha, Chou, Wayne K. W., Cane, David E., Christianson, David W.
Published in Biochemistry (Easton) (08.12.2015)
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Published in Biochemistry (Easton) (08.12.2015)
Journal Article
Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: Probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233– Mg 2 + B motif
Vedula, L. Sangeetha, Jiang, Jiaoyang, Zakharian, Tatiana, Cane, David E., Christianson, David W.
Published in Archives of biochemistry and biophysics (2008)
Published in Archives of biochemistry and biophysics (2008)
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Journal Article
Structural and Mechanistic Analysis of Trichodiene Synthase using Site-Directed Mutagenesis: Probing the Catalytic Function of Tyrosine-295 and the Asparagine-225/Serine-229/Glutamate-233–Mg2+B MotifI, II
Vedula, L. Sangeetha, Jiang, Jiaoyang, Zakharian, Tatiana, Cane, David E., Christianson, David W.
Published in Archives of biochemistry and biophysics (30.10.2007)
Published in Archives of biochemistry and biophysics (30.10.2007)
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Journal Article
Structural and mechanistic analysis of trichodiene synthase using site-directed mutagenesis: probing the catalytic function of tyrosine-295 and the asparagine-225/serine-229/glutamate-233-Mg2+B motif
Vedula, L Sangeetha, Jiang, Jiaoyang, Zakharian, Tatiana, Cane, David E, Christianson, David W
Published in Archives of biochemistry and biophysics (15.01.2008)
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Published in Archives of biochemistry and biophysics (15.01.2008)
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