Soat2 ties cholesterol metabolism to β‐oxidation and glucose tolerance in male mice
Pramfalk, Camilla, Ahmed, Osman, Pedrelli, Matteo, Minniti, Mirko E., Luquet, Serge, Denis, Raphaël GP, Olin, Maria, Härdfeldt, Jennifer, Vedin, Lise‐Lotte, Steffensen, Knut R, Rydén, Mikael, Hodson, Leanne, Eriksson, Mats, Parini, Paolo
Published in Journal of internal medicine (01.08.2022)
Published in Journal of internal medicine (01.08.2022)
Get full text
Journal Article
Hepatocyte-specific loss of GPS2 in mice reduces non-alcoholic steatohepatitis via activation of PPARα
Liang, Ning, Damdimopoulos, Anastasius, Goñi, Saioa, Huang, Zhiqiang, Vedin, Lise-Lotte, Jakobsson, Tomas, Giudici, Marco, Ahmed, Osman, Pedrelli, Matteo, Barilla, Serena, Alzaid, Fawaz, Mendoza, Arturo, Schröder, Tarja, Kuiper, Raoul, Parini, Paolo, Hollenberg, Anthony, Lefebvre, Philippe, Francque, Sven, Van Gaal, Luc, Staels, Bart, Venteclef, Nicolas, Treuter, Eckardt, Fan, Rongrong
Published in Nature communications (11.04.2019)
Published in Nature communications (11.04.2019)
Get full text
Journal Article
The lipid droplet-associated protein perilipin 3 facilitates hepatitis C virus-driven hepatic steatosis
Ferguson, Daniel, Zhang, Jun, Davis, Matthew A., Helsley, Robert N., Vedin, Lise-Lotte, Lee, Richard G., Crooke, Rosanne M., Graham, Mark J., Allende, Daniela S., Parini, Paolo, Brown, J.Mark
Published in Journal of lipid research (01.02.2017)
Published in Journal of lipid research (01.02.2017)
Get full text
Journal Article
Insights From Liver‐Humanized Mice on Cholesterol Lipoprotein Metabolism and LXR‐Agonist Pharmacodynamics in Humans
Minniti, Mirko E., Pedrelli, Matteo, Vedin, Lise‐Lotte, Delbès, Anne‐Sophie, Denis, Raphaël G.P., Öörni, Katariina, Sala, Claudia, Pirazzini, Chiara, Thiagarajan, Divya, Nurmi, Harri J., Grompe, Markus, Mills, Kevin, Garagnani, Paolo, Ellis, Ewa C.S., Strom, Stephen C., Luquet, Serge H., Wilson, Elizabeth M., Bial, John, Steffensen, Knut R., Parini, Paolo
Published in Hepatology (Baltimore, Md.) (01.08.2020)
Published in Hepatology (Baltimore, Md.) (01.08.2020)
Get full text
Journal Article
Liver X receptors induce antiproliferative effects in basal-like breast cancer
Haugen, Mads Haugland, von der Lippe Gythfeldt, Hedda, Egeland, Eivind Valen, Svartdal Normann, Lisa, Pandya, Abhilash D, Vedin, Lise-Lotte, Juell, Siri, Tenstad, Ellen, Øy, Geir Frode, Kristian, Alexandr, Marangoni, Elisabetta, Sørlie, Therese, Steffensen, Knut, Maelandsmo, Gunhild Mari, Engebraaten, Olav
Published in Molecular oncology (01.10.2023)
Published in Molecular oncology (01.10.2023)
Get full text
Journal Article
The oxysterol receptors lxrα and lxrβ suppress proliferation in the colon
Vedin, Lise-Lotte, Gustafsson, Jan-Åke, Steffensen, Knut R.
Published in Molecular carcinogenesis (01.11.2013)
Published in Molecular carcinogenesis (01.11.2013)
Get full text
Journal Article
Liver × receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism
Nguyen-Vu, Trang, Vedin, Lise-Lotte, Liu, Ka, Jonsson, Philip, Lin, Jean Z, Candelaria, Nicholes R, Candelaria, Lindsay P, Addanki, Sridevi, Williams, Cecilia, Gustafsson, Jan-Åke, Steffensen, Knut R, Lin, Chin-Yo
Published in Breast cancer research : BCR (20.06.2013)
Published in Breast cancer research : BCR (20.06.2013)
Get full text
Journal Article
Knockdown of SF-1 and RNF31 affects components of steroidogenesis, TGFβ, and Wnt/β-catenin signaling in adrenocortical carcinoma cells
Ehrlund, Anna, Jonsson, Philip, Vedin, Lise-Lotte, Williams, Cecilia, Gustafsson, Jan-Åke, Treuter, Eckardt
Published in PloS one (2012)
Published in PloS one (2012)
Get full text
Journal Article
Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice
Han, Song‐iee, Komatsu, Yoko, Murayama, Akiko, Steffensen, Knut R., Nakagawa, Yoshimi, Nakajima, Yuka, Suzuki, Michiko, Oie, Shohei, Parini, Paolo, Vedin, Lise‐Lotte, Kishimoto, Hiroyuki, Shimano, Hitoshi, Gustafsson, Jan‐Åke, Yanagisawa, Junn
Published in Hepatology (Baltimore, Md.) (01.05.2014)
Published in Hepatology (Baltimore, Md.) (01.05.2014)
Get full text
Journal Article
The emerging roles of liver X receptors and their ligands in cancer
Lin, Chin-Yo, Vedin, Lise-Lotte, Steffensen, Knut R
Published in Expert opinion on therapeutic targets (02.01.2016)
Published in Expert opinion on therapeutic targets (02.01.2016)
Get more information
Journal Article
Antiproliferative effects and mechanisms of liver X receptor ligands in pancreatic ductal adenocarcinoma cells
Candelaria, Nicholes R, Addanki, Sridevi, Zheng, Jine, Nguyen-Vu, Trang, Karaboga, Husna, Dey, Prasenjit, Gabbi, Chiara, Vedin, Lise-Lotte, Liu, Ka, Wu, Wanfu, Jonsson, Philip K, Lin, Jean Z, Su, Fei, Bollu, Lakshmi Reddy, Hodges, Sally E, McElhany, Amy L, Issazadeh, Mehdi A, Fisher, William E, Ittmann, Michael M, Steffensen, Knut R, Gustafsson, Jan-Åke, Lin, Chin-Yo
Published in PloS one (03.09.2014)
Published in PloS one (03.09.2014)
Get full text
Journal Article
Liver-humanized mice exhibit lipoprotein-specific phenotypes when grafted with human hepatocytes from different donors
Minniti, Mirko E., Vedin, Lise -Lotte, Wilson, Elizabeth M., Steffensen, Knut R., Parini, Paolo
Published in ATHEROSCLEROSIS (01.08.2017)
Published in ATHEROSCLEROSIS (01.08.2017)
Get full text
Journal Article
Conference Proceeding
Mice with humanized livers reveal the role of hepatocyte clocks in rhythmic behavior
Delbès, Anne-Sophie, Quiñones, Mar, Gobet, Cédric, Castel, Julien, Denis, Raphaël G P, Berthelet, Jérémy, Weger, Benjamin D, Challet, Etienne, Charpagne, Aline, Metairon, Sylviane, Piccand, Julie, Kraus, Marine, Rohde, Bettina H, Bial, John, Wilson, Elizabeth M, Vedin, Lise-Lotte, Minniti, Mirko E, Pedrelli, Matteo, Parini, Paolo, Gachon, Frédéric, Luquet, Serge
Published in Science advances (19.05.2023)
Published in Science advances (19.05.2023)
Get full text
Journal Article
Estrogen receptor ligands ameliorate fatty liver through a nonclassical estrogen receptor/Liver X receptor pathway in mice
Han, SI, Komatsu, Y, Murayama, A, Steffensen, KR, Nakagawa, Y, Nakajima, Y, Suzuki, M, Oie, S, Parini, P, Vedin, LL, Kishimoto, H, Shimano, H, Gustafsson, JA, Yanagisawa, J
Published in Hepatology (Baltimore, Md.) (2014)
Published in Hepatology (Baltimore, Md.) (2014)
Get full text
Journal Article
Liver X receptors induce antiproliferative effects in basal-like breast cancer
Haugen, Mads, von der Lippe Gythfeldt, Hedda, Egeland, Eivind Valen, Svartdal Normann, Lisa, Pandya, Abhilash D, Vedin, Lise-Lotte, Juell, Siri, Tenstad, Ellen, Øy, Geir Frode, Kristian, Alexandr, Marangoni, Elisabetta, Sørlie, Therese, Steffensen, Knut Rune, Mælandsmo, Gunhild Mari, Engebråten, Olav
Published in Molecular oncology (2023)
Get full text
Published in Molecular oncology (2023)
Journal Article
Liver x receptor ligands disrupt breast cancer cell proliferation through an E2F-mediated mechanism
Nguyen-Vu, Trang, Vedin, Lise-Lotte, Liu, Ka, Jonsson, Philip, Lin, Jean Z, Candelaria, Nicholes R, Candelaria, Lindsay P, Addanki, Sridevi, Williams, Cecilia, Gustafsson, Jan-Ãke, Steffensen, Knut R, Lin, Chin-Yo
Published in Breast cancer research : BCR (20.06.2013)
Published in Breast cancer research : BCR (20.06.2013)
Get full text
Journal Article
The oxysterol receptors lxr[alpha] and lxr[beta] suppress proliferation in the colon
Vedin, Lise-Lotte, Gustafsson, Jan-Åke, Steffensen, Knut R
Published in Molecular carcinogenesis (01.11.2013)
Published in Molecular carcinogenesis (01.11.2013)
Get full text
Journal Article
Knockdown of SF-1 and RNF31 Affects Components of Steroidogenesis, TGF[beta], and Wnt/[beta]-catenin Signaling in Adrenocortical Carcinoma Cells
Ehrlund, Anna, Jonsson, Philip, Vedin, Lise-Lotte, Williams, Cecilia, Gustafsson, Jan-Åke, Treuter, Eckardt
Published in PloS one (09.03.2012)
Published in PloS one (09.03.2012)
Get full text
Journal Article