Engineering designer beta cells with a CRISPR-Cas9 conjugation platform
Lim, Donghyun, Sreekanth, Vedagopuram, Cox, Kurt J., Law, Benjamin K., Wagner, Bridget K., Karp, Jeffrey M., Choudhary, Amit
Published in Nature communications (13.08.2020)
Published in Nature communications (13.08.2020)
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Journal Article
Bile Acid Tethered Docetaxel‐Based Nanomicelles Mitigate Tumor Progression through Epigenetic Changes
Sreekanth, Vedagopuram, Kar, Animesh, Kumar, Sandeep, Pal, Sanjay, Yadav, Poonam, Sharma, Yamini, Komalla, Varsha, Sharma, Harsh, Shyam, Radhey, Sharma, Ravi Datta, Mukhopadhyay, Arnab, Sengupta, Sagar, Dasgupta, Ujjaini, Bajaj, Avinash
Published in Angewandte Chemie International Edition (01.03.2021)
Published in Angewandte Chemie International Edition (01.03.2021)
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Journal Article
Continuous evolution of compact protein degradation tags regulated by selective molecular glues
Mercer, Jaron A M, DeCarlo, Stephan J, Roy Burman, Shourya S, Sreekanth, Vedagopuram, Nelson, Andrew T, Hunkeler, Moritz, Chen, Peter J, Donovan, Katherine A, Kokkonda, Praveen, Tiwari, Praveen K, Shoba, Veronika M, Deb, Arghya, Choudhary, Amit, Fischer, Eric S, Liu, David R
Published in Science (American Association for the Advancement of Science) (15.03.2024)
Published in Science (American Association for the Advancement of Science) (15.03.2024)
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Journal Article
Self-assembled supramolecular nanomicelles from a bile acid-docetaxel conjugate are highly tolerable with improved therapeutic efficacy
Sreekanth, Vedagopuram, Pal, Sanjay, Kumar, Sandeep, Komalla, Varsha, Yadav, Poonam, Shyam, Radhey, Sengupta, Sagar, Bajaj, Avinash
Published in Biomaterials science (21.08.2021)
Published in Biomaterials science (21.08.2021)
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Journal Article
Bile Acid Tethered Docetaxel‐Based Nanomicelles Mitigate Tumor Progression through Epigenetic Changes
Sreekanth, Vedagopuram, Kar, Animesh, Kumar, Sandeep, Pal, Sanjay, Yadav, Poonam, Sharma, Yamini, Komalla, Varsha, Sharma, Harsh, Shyam, Radhey, Sharma, Ravi Datta, Mukhopadhyay, Arnab, Sengupta, Sagar, Dasgupta, Ujjaini, Bajaj, Avinash
Published in Angewandte Chemie (01.03.2021)
Published in Angewandte Chemie (01.03.2021)
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Journal Article
Chemogenetic System Demonstrates That Cas9 Longevity Impacts Genome Editing Outcomes
Sreekanth, Vedagopuram, Zhou, Qingxuan, Kokkonda, Praveen, Bermudez-Cabrera, Heysol C, Lim, Donghyun, Law, Benjamin K, Holmes, Benjamin R, Chaudhary, Santosh K, Pergu, Rajaiah, Leger, Brittany S, Walker, James A, Gifford, David K, Sherwood, Richard I, Choudhary, Amit
Published in ACS central science (23.12.2020)
Published in ACS central science (23.12.2020)
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Journal Article
Recent Advances in Engineering of Lipid Drug Conjugates for Cancer Therapy
Sreekanth, Vedagopuram, Bajaj, Avinash
Published in ACS biomaterials science & engineering (09.09.2019)
Published in ACS biomaterials science & engineering (09.09.2019)
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Journal Article
A molecular glue approach to control the half-life of CRISPR-based technologies
Sreekanth, Vedagopuram, Jan, Max, Zhao, Kevin T, Lim, Donghyun, Davis, Jessie R, McConkey, Marie, Kovalcik, Veronica, Barkal, Sam, Law, Benjamin K, Fife, James, Tian, Ruilin, Vinyard, Michael E, Becerra, Basheer, Kampmann, Martin Edward, Sherwood, Richard I, Pinello, Luca, Liu, David R, Ebert, Benjamin L, Choudhary, Amit
Published in bioRxiv (20.03.2023)
Published in bioRxiv (20.03.2023)
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Journal Article
Paper
Injectable small molecule hydrogel as a potential nanocarrier for localized and sustained in vivo delivery of doxorubicin
Singh, Manish, Kundu, Somanath, Reddy M, Amarendar, Sreekanth, Vedagopuram, Motiani, Rajender K, Sengupta, Sagar, Srivastava, Aasheesh, Bajaj, Avinash
Published in Nanoscale (07.11.2014)
Published in Nanoscale (07.11.2014)
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Journal Article
Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models
Kaur, Ekjot, Agrawal, Ritu, Arun, Rimpy, Madhavan, Vinoth, Srivastava, Vivek, Kumar, Dilip, Rath, Pragyan Parimita, Kumar, Nitin, Vedagopuram, Sreekanth, Pandey, Nishant, Priya, Swati, Legembre, Patrick, Gourinath, Samudrala, Bajaj, Avinash, Sengupta, Sagar
Published in The Journal of clinical investigation (15.04.2024)
Published in The Journal of clinical investigation (15.04.2024)
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Journal Article
Small molecules that disrupt RAD54-BLM interaction hamper tumor proliferation in colon cancer chemoresistance models
Kaur, Ekjot, Agrawal, Ritu, Arun, Rimpy, Madhavan, Vinoth, Srivastava, Vivek, Kumar, Dilip, Rath, Pragyan Parimita, Kumar, Nitin, Vedagopuram, Sreekanth, Pandey, Nishant, Priya, Swati, Legembre, Patrick, Gourinath, Samudrala, Bajaj, Avinash, Sengupta, Sagar
Published in The Journal of clinical investigation (01.04.2024)
Published in The Journal of clinical investigation (01.04.2024)
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Journal Article
Proteolysis-targeting chimeras with reduced off-targets
Nguyen, Tuan M., Sreekanth, Vedagopuram, Deb, Arghya, Kokkonda, Praveen, Tiwari, Praveen K., Donovan, Katherine A., Shoba, Veronika, Chaudhary, Santosh K., Mercer, Jaron A. M., Lai, Sophia, Sadagopan, Ananthan, Jan, Max, Fischer, Eric S., Liu, David R., Ebert, Benjamin L., Choudhary, Amit
Published in Nature chemistry (01.02.2024)
Published in Nature chemistry (01.02.2024)
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Journal Article
Design, regioselective synthesis and cytotoxic evaluation of 2-aminoimidazole–quinoline hybrids against cancer and primary endothelial cells
Singh, Kuldeep, Verma, Vikas, Yadav, Kavita, Sreekanth, Vedagopuram, Kumar, Devinder, Bajaj, Avinash, Kumar, Vinod
Published in European journal of medicinal chemistry (24.11.2014)
Published in European journal of medicinal chemistry (24.11.2014)
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Journal Article
Design, synthesis, and physico-chemical interactions of bile acid derived dimeric phospholipid amphiphiles with model membranes
Kumar, Sandeep, Bhargava, Priyanshu, Sreekanth, Vedagopuram, Bajaj, Avinash
Published in Journal of colloid and interface science (15.06.2015)
Published in Journal of colloid and interface science (15.06.2015)
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Journal Article
FALCON systematically interrogates free fatty acid biology and identifies a novel mediator of lipotoxicity
Wieder, Nicolas, Fried, Juliana Coraor, Kim, Choah, Sidhom, Eriene-Heidi, Brown, Matthew R., Marshall, Jamie L., Arevalo, Carlos, Dvela-Levitt, Moran, Kost-Alimova, Maria, Sieber, Jonas, Gabriel, Katlyn R., Pacheco, Julian, Clish, Clary, Abbasi, Hamdah Shafqat, Singh, Shantanu, Rutter, Justine C., Therrien, Martine, Yoon, Haejin, Lai, Zon Weng, Baublis, Aaron, Subramanian, Renuka, Devkota, Ranjan, Small, Jonnell, Sreekanth, Vedagopuram, Han, Myeonghoon, Lim, Donghyun, Carpenter, Anne E., Flannick, Jason, Finucane, Hilary, Haigis, Marcia C., Claussnitzer, Melina, Sheu, Eric, Stevens, Beth, Wagner, Bridget K., Choudhary, Amit, Shaw, Jillian L., Pablo, Juan Lorenzo, Greka, Anna
Published in Cell metabolism (02.05.2023)
Published in Cell metabolism (02.05.2023)
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Journal Article