High-Definition Reconstruction of Clonal Composition in Cancer
Fischer, Andrej, Vázquez-García, Ignacio, Illingworth, Christopher J.R., Mustonen, Ville
Published in Cell reports (Cambridge) (12.06.2014)
Published in Cell reports (Cambridge) (12.06.2014)
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Journal Article
value of monitoring to control evolving populations
Fischer, Andrej, Vázquez-García, Ignacio, Mustonen, Ville
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (27.01.2015)
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Inferring replication timing and proliferation dynamics from single-cell DNA sequencing data
Weiner, Adam C., Williams, Marc J., Shi, Hongyu, Vázquez-García, Ignacio, Salehi, Sohrab, Rusk, Nicole, Aparicio, Samuel, Shah, Sohrab P., McPherson, Andrew
Published in Nature communications (01.10.2024)
Published in Nature communications (01.10.2024)
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Contrasting the impact of cytotoxic and cytostatic drug therapies on tumour progression
Anttila, Jani V, Shubin, Mikhail, Cairns, Johannes, Borse, Florian, Guo, Qingli, Mononen, Tommi, Vázquez-García, Ignacio, Pulkkinen, Otto, Mustonen, Ville
Published in PLoS computational biology (01.11.2019)
Published in PLoS computational biology (01.11.2019)
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Insights on Future Directions in Cancer Research from the AACR NextGen Stars
Cañadas, Israel, Casirati, Gabriele, Houlahan, Kathleen E, Maxwell, Kara N, Mehta, Arnav, Parolia, Abhijit, Saulnier, Olivier, Taylor, Alison M, Thomas, Claire E, Vázquez-García, Ignacio
Published in Cancer discovery (04.09.2024)
Published in Cancer discovery (04.09.2024)
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Clonal Heterogeneity Influences the Fate of New Adaptive Mutations
Vázquez-García, Ignacio, Salinas, Francisco, Li, Jing, Fischer, Andrej, Barré, Benjamin, Hallin, Johan, Bergström, Anders, Alonso-Perez, Elisa, Warringer, Jonas, Mustonen, Ville, Liti, Gianni
Published in Cell reports (Cambridge) (17.10.2017)
Published in Cell reports (Cambridge) (17.10.2017)
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Journal Article
Abstract 869: Single-cell DNA replication dynamics in genomically unstable cancers
Weiner, Adam C., Williams, Marc, Shi, Hongyu, Vazquez-Garcia, Ignacio, Salehi, Sohrab, Rusk, Nicole, Shah, Sohrab P., McPherson, Andrew
Published in Cancer research (Chicago, Ill.) (22.03.2024)
Published in Cancer research (Chicago, Ill.) (22.03.2024)
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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
Dentro, Stefan C., Leshchiner, Ignaty, Haase, Kerstin, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Vázquez-García, Ignacio, Kleinheinz, Kortine, Livitz, Dimitri G., Malikic, Salem, Donmez, Nilgun, Sengupta, Subhajit, Anur, Pavana, Jolly, Clemency, Rosebrock, Daniel, Schumacher, Steven E., Fittall, Matthew, Drews, Ruben M., Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Zhu, Hongtu, Adams, David J., McGranahan, Nicholas, Swanton, Charles, Getz, Gad, Boutros, Paul C., Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Martincorena, Inigo, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Gerstung, Moritz, Spellman, Paul T., Wang, Wenyi, Wedge, David C., Dentro, Stefan C., Leshchiner, Ignaty, Gerstung, Moritz, Jolly, Clemency, Haase, Kerstin, Tarabichi, Maxime, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D., Cao, Shaolong, Cmero, Marek, Cun, Yupeng, Dawson, Kevin J., Donmez, Nilgun, Drews, Ruben M., Eils, Roland, Fan, Yu, Fittall, Matthew, Getz, Gad, Ha, Gavin, Imielinski, Marcin, Ji, Yuan, Kleinheinz, Kortine, Lee, Juhee, Lee-Six, Henry, Livitz, Dimitri G., Malikic, Salem, Markowetz, Florian, Martincorena, Inigo, Mustonen, Ville, Oesper, Layla, Peifer, Martin, Peto, Myron, Raphael, Benjamin J., Rosebrock, Daniel, Salcedo, Adriana, Schumacher, Steven E., Sengupta, Subhajit, Shi, Ruian, Spiro, Oliver, Vázquez-García, Ignacio, Vembu, Shankar, Wheeler, David A., Yao, Xiaotong, Yuan, Ke, Wang, Wenyi, Morris, Quaid D., Spellman, Paul T., Wedge, David C., Van Loo, Peter
Published in Cell (15.04.2021)
Published in Cell (15.04.2021)
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Journal Article
EP299/#232 Genomic instability as a determinant of immune escape in ovarian cancer
Vazquez-Garcia, Ignacio, Uhlitz, Florian, Ceglia, Nicholas, Lim, Jamie, Wu, Michelle, Mohibullah, Neeman, Niyazov, Juliana, Ruiz, Arvin Eric, Soslow, Robert, Ellenson, Lora, Abu-Rustum, Nadeem, Aghajanian, Carol, Friedman, Claire, Mcpherson, Andrew, Weigelt, Britta, Zamarin, Dmitriy, Shah, Sohrab
Published in International journal of gynecological cancer (04.12.2022)
Published in International journal of gynecological cancer (04.12.2022)
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Journal Article
Ovarian cancer mutational processes drive site-specific immune evasion
Vázquez-García, Ignacio, Uhlitz, Florian, Ceglia, Nicholas, Lim, Jamie L. P., Wu, Michelle, Mohibullah, Neeman, Niyazov, Juliana, Ruiz, Arvin Eric B., Boehm, Kevin M., Bojilova, Viktoria, Fong, Christopher J., Funnell, Tyler, Grewal, Diljot, Havasov, Eliyahu, Leung, Samantha, Pasha, Arfath, Patel, Druv M., Pourmaleki, Maryam, Rusk, Nicole, Shi, Hongyu, Vanguri, Rami, Williams, Marc J., Zhang, Allen W., Broach, Vance, Chi, Dennis S., Da Cruz Paula, Arnaud, Gardner, Ginger J., Kim, Sarah H., Lennon, Matthew, Long Roche, Kara, Sonoda, Yukio, Zivanovic, Oliver, Kundra, Ritika, Viale, Agnes, Derakhshan, Fatemeh N., Geneslaw, Luke, Issa Bhaloo, Shirin, Maroldi, Ana, Nunez, Rahelly, Pareja, Fresia, Stylianou, Anthe, Vahdatinia, Mahsa, Bykov, Yonina, Grisham, Rachel N., Liu, Ying L., Lakhman, Yulia, Nikolovski, Ines, Kelly, Daniel, Gao, Jianjiong, Schietinger, Andrea, Hollmann, Travis J., Bakhoum, Samuel F., Soslow, Robert A., Ellenson, Lora H., Abu-Rustum, Nadeem R., Aghajanian, Carol, Friedman, Claire F., McPherson, Andrew, Weigelt, Britta, Zamarin, Dmitriy, Shah, Sohrab P.
Published in Nature (London) (22.12.2022)
Published in Nature (London) (22.12.2022)
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Journal Article
Abstract 102: Transient chromosomal instability as a driver of ovarian cancer genome evolution
Vazquez-Garcia, Ignacio, Uhlitz, Florian, Williams, Marc J., Li, Jun, Shi, Hongyu, Freeman, Samuel, Myers, Matthew, Consortium, MSK SPECTRUM, Weigelt, Britta, Zamarin, Dmitriy, McPherson, Andrew, Bakhoum, Samuel F., Shah, Sohrab P.
Published in Cancer research (Chicago, Ill.) (29.05.2023)
Published in Cancer research (Chicago, Ill.) (29.05.2023)
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Fundamental immune–oncogenicity trade-offs define driver mutation fitness
Hoyos, David, Zappasodi, Roberta, Schulze, Isabell, Sethna, Zachary, de Andrade, Kelvin César, Bajorin, Dean F., Bandlamudi, Chaitanya, Callahan, Margaret K., Funt, Samuel A., Hadrup, Sine R., Holm, Jeppe S., Rosenberg, Jonathan E., Shah, Sohrab P., Vázquez-García, Ignacio, Weigelt, Britta, Wu, Michelle, Zamarin, Dmitriy, Campitelli, Laura F., Osborne, Edward J., Klinger, Mark, Robins, Harlan S., Khincha, Payal P., Savage, Sharon A., Balachandran, Vinod P., Wolchok, Jedd D., Hellmann, Matthew D., Merghoub, Taha, Levine, Arnold J., Łuksza, Marta, Greenbaum, Benjamin D.
Published in Nature (London) (02.06.2022)
Published in Nature (London) (02.06.2022)
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Single-cell mtDNA dynamics in tumors is driven by coregulation of nuclear and mitochondrial genomes
Kim, Minsoo, Gorelick, Alexander N., Vàzquez-García, Ignacio, Williams, Marc J., Salehi, Sohrab, Shi, Hongyu, Weiner, Adam C., Ceglia, Nick, Funnell, Tyler, Park, Tricia, Boscenco, Sonia, O’Flanagan, Ciara H., Jiang, Hui, Grewal, Diljot, Tang, Cerise, Rusk, Nicole, Gammage, Payam A., McPherson, Andrew, Aparicio, Sam, Shah, Sohrab P., Reznik, Ed
Published in Nature genetics (01.05.2024)
Published in Nature genetics (01.05.2024)
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Shared Molecular Targets Confer Resistance over Short and Long Evolutionary Timescales
Li, Jing, Vázquez-García, Ignacio, Persson, Karl, González, Asier, Yue, Jia-Xing, Barré, Benjamin, Hall, Michael N, Long, Anthony, Warringer, Jonas, Mustonen, Ville, Liti, Gianni
Published in Molecular biology and evolution (01.04.2019)
Published in Molecular biology and evolution (01.04.2019)
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Imaging and Molecular Annotation of Xenographs and Tumours (IMAXT): High throughput data and analysis infrastructure
González-Solares, Eduardo A, Dariush, Ali, González-Fernández, Carlos, Küpcü Yoldaş, Aybüke, Molaeinezhad, Alireza, Al Sa'd, Mohammad, Smith, Leigh, Whitmarsh, Tristan, Millar, Neil, Chornay, Nicholas, Falciatori, Ilaria, Fatemi, Atefeh, Goodwin, Daniel, Kuett, Laura, Mulvey, Claire M, Páez Ribes, Marta, Qosaj, Fatime, Roth, Andrew, Vázquez-García, Ignacio, Watson, Spencer S, Windhager, Jonas, Aparicio, Samuel, Bodenmiller, Bernd, Boyden, Ed, Caldas, Carlos, Harris, Owen, Shah, Sohrab P, Tavaré, Simon, Bressan, Dario, Hannon, Gregory J, Walton, Nicholas A
Published in Biological imaging (Cambridge, England) (2023)
Published in Biological imaging (Cambridge, England) (2023)
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MULTI-MODAL MACHINE LEARNING TO DETERMINE RISK STRATIFICATION
GAO, Jianjiong, BOEHM, Kevin, ELLENSON, Lora, AHERNE, Emily, ZAMARIN, Dmitriy, LAKHMAN, Yulia, NIKOLOVSKI, Ines, PATEL, Druv, SHAH, Sohrab P, VAZQUEZ GARCIA, Ignacio
Year of Publication 19.10.2023
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Year of Publication 19.10.2023
Patent
The repertoire of mutational signatures in human cancer
Alexandrov, Ludmil B., Kim, Jaegil, Haradhvala, Nicholas J., Huang, Mi Ni, Tian Ng, Alvin Wei, Wu, Yang, Boot, Arnoud, Covington, Kyle R., Gordenin, Dmitry A., Bergstrom, Erik N., Islam, S. M. Ashiqul, Lopez-Bigas, Nuria, Klimczak, Leszek J., McPherson, John R., Morganella, Sandro, Sabarinathan, Radhakrishnan, Wheeler, David A., Mustonen, Ville, Getz, Gad, Rozen, Steven G., Stratton, Michael R.
Published in Nature (London) (06.02.2020)
Published in Nature (London) (06.02.2020)
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The evolutionary history of 2,658 cancers
Gerstung, Moritz, Jolly, Clemency, Leshchiner, Ignaty, Dentro, Stefan C., Gonzalez, Santiago, Rosebrock, Daniel, Mitchell, Thomas J., Rubanova, Yulia, Anur, Pavana, Yu, Kaixian, Tarabichi, Maxime, Deshwar, Amit, Wintersinger, Jeff, Kleinheinz, Kortine, Vázquez-García, Ignacio, Haase, Kerstin, Jerman, Lara, Sengupta, Subhajit, Macintyre, Geoff, Malikic, Salem, Donmez, Nilgun, Livitz, Dimitri G., Cmero, Marek, Demeulemeester, Jonas, Schumacher, Steven, Fan, Yu, Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Boutros, Paul C., Bowtell, David D., Zhu, Hongtu, Getz, Gad, Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Wang, Wenyi, Morris, Quaid D., Spellman, Paul T., Wedge, David C., Van Loo, Peter
Published in Nature (London) (06.02.2020)
Published in Nature (London) (06.02.2020)
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Patterns of somatic structural variation in human cancer genomes
Li, Yilong, Roberts, Nicola D., Wala, Jeremiah A., Shapira, Ofer, Schumacher, Steven E., Kumar, Kiran, Khurana, Ekta, Waszak, Sebastian, Korbel, Jan O., Haber, James E., Imielinski, Marcin, Weischenfeldt, Joachim, Beroukhim, Rameen, Campbell, Peter J.
Published in Nature (London) (06.02.2020)
Published in Nature (London) (06.02.2020)
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