TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing
Schöpp, Theresa, Zoch, Ansgar, Berrens, Rebecca V., Auchynnikava, Tania, Kabayama, Yuka, Vasiliauskaitė, Lina, Rappsilber, Juri, Allshire, Robin C., O’Carroll, Dónal
Published in Nature communications (27.07.2020)
Published in Nature communications (27.07.2020)
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Journal Article
NSUN2 introduces 5-methylcytosines in mammalian mitochondrial tRNAs
Van Haute, Lindsey, Lee, Song-Yi, McCann, Beverly J, Powell, Christopher A, Bansal, Dhiru, Vasiliauskaitė, Lina, Garone, Caterina, Shin, Sanghee, Kim, Jong-Seo, Frye, Michaela, Gleeson, Joseph G, Miska, Eric A, Rhee, Hyun-Woo, Minczuk, Michal
Published in Nucleic acids research (19.09.2019)
Published in Nucleic acids research (19.09.2019)
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Journal Article
SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation
Zoch, Ansgar, Auchynnikava, Tania, Berrens, Rebecca V., Kabayama, Yuka, Schöpp, Theresa, Heep, Madeleine, Vasiliauskaitė, Lina, Pérez-Rico, Yuvia A., Cook, Atlanta G., Shkumatava, Alena, Rappsilber, Juri, Allshire, Robin C., O’Carroll, Dónal
Published in Nature (London) (27.08.2020)
Published in Nature (London) (27.08.2020)
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Journal Article
Animal Hen1 2′-O-methyltransferases as tools for 3′-terminal functionalization and labelling of single-stranded RNAs
Mickutė, Milda, Nainytė, Milda, Vasiliauskaitė, Lina, Plotnikova, Alexandra, Masevičius, Viktoras, Klimašauskas, Saulius, Vilkaitis, Giedrius
Published in Nucleic acids research (28.09.2018)
Published in Nucleic acids research (28.09.2018)
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Journal Article
A programmed wave of uridylation-primed mRNA degradation is essential for meiotic progression and mammalian spermatogenesis
Morgan, Marcos, Kabayama, Yuka, Much, Christian, Ivanova, Ivayla, Di Giacomo, Monica, Auchynnikava, Tatsiana, Monahan, Jack Michael, Vitsios, Dimitrios Michael, Vasiliauskaitė, Lina, Comazzetto, Stefano, Rappsilber, Juri, Allshire, Robin Campbell, Porse, Bo Torben, Enright, Anton James, O’Carroll, Dónal
Published in Cell research (01.03.2019)
Published in Cell research (01.03.2019)
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Journal Article
A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming
Vasiliauskaitė, Lina, Vitsios, Dimitrios, Berrens, Rebecca V, Carrieri, Claudia, Reik, Wolf, Enright, Anton J, O'Carroll, Dónal
Published in Nature structural & molecular biology (01.07.2017)
Published in Nature structural & molecular biology (01.07.2017)
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Journal Article
NANOS2 is a sequence-specific mRNA-binding protein that promotes transcript degradation in spermatogonial stem cells
Codino, Azzurra, Turowski, Tomasz, van de Lagemaat, Louie N., Ivanova, Ivayla, Tavosanis, Andrea, Much, Christian, Auchynnikava, Tania, Vasiliauskaitė, Lina, Morgan, Marcos, Rappsilber, Juri, Allshire, Robin C., Kranc, Kamil R., Tollervey, David, O'Carroll, Dónal
Published in iScience (23.07.2021)
Published in iScience (23.07.2021)
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Journal Article
Multiple Epigenetic Mechanisms and the piRNA Pathway Enforce LINE1 Silencing during Adult Spermatogenesis
Di Giacomo, Monica, Comazzetto, Stefano, Saini, Harpreet, De Fazio, Serena, Carrieri, Claudia, Morgan, Marcos, Vasiliauskaite, Lina, Benes, Vladimir, Enright, Anton J., O’Carroll, Dónal
Published in Molecular cell (23.05.2013)
Published in Molecular cell (23.05.2013)
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Journal Article
Abstract C077: STC-15, a small molecule inhibitor of the RNA methyltransferase METTL3, activates anti-tumor immunity and reshapes the tumor microenvironment
Ofir-Rosenfeld, Yaara, Vasiliauskaitė, Lina, Obacz, Joanna, Tsagkogeorga, Georgia, Holz, Josefin-Beate, McMahon, Jerry, Rausch, Oliver
Published in Molecular cancer therapeutics (01.12.2023)
Published in Molecular cancer therapeutics (01.12.2023)
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Journal Article
Inhibition of METTL3 Results in a Cell-Intrinsic Interferon Response That Enhances Antitumor Immunity
Guirguis, Andrew A., Ofir-Rosenfeld, Yaara, Knezevic, Kathy, Blackaby, Wesley, Hardick, David, Chan, Yih-Chih, Motazedian, Ali, Gillespie, Andrea, Vassiliadis, Dane, Lam, Enid Y.N., Tran, Kevin, Andrews, Byron, Harbour, Michael E., Vasiliauskaite, Lina, Saunders, Claire J., Tsagkogeorga, Georgia, Azevedo, Aleksandra, Obacz, Joanna, Pilka, Ewa S., Carkill, Marie, MacPherson, Laura, Wainwright, Elanor N., Liddicoat, Brian, Blyth, Benjamin J., Albertella, Mark R., Rausch, Oliver, Dawson, Mark A.
Published in Cancer discovery (05.10.2023)
Published in Cancer discovery (05.10.2023)
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Journal Article
Abstract A18: STC-15, a novel METTL3 inhibitor, and its combination with Venetoclax confer anti-tumour activity in AML models
Vasiliauskaite, Lina, Ofir-Rosenfeld, Yaara, Albertella, Mark, Hoareau-Aveilla, Coralie, McMahon, Jerry, Rausch, Oliver
Published in Blood cancer discovery (01.05.2023)
Published in Blood cancer discovery (01.05.2023)
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Journal Article
Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances anti-tumour immunity
Guirguis, Andrew A, Ofir-Rosenfeld, Yaara, Knezevic, Kathy, Blackaby, Wesley, Hardick, David, Chan, Yih-Chih, Motazedian, Ali, Gillespie, Andrea, Vassiliadis, Dane, Lam, Enid Yn, Tran, Kevin, Andrews, Byron, Harbour, Michael E, Vasiliauskaite, Lina, Saunders, Claire J, Tsagkogeorga, Georgia, Azevedo, Aleksandra, Obacz, Joanna, Pilka, Ewa S, Carkill, Marie, MacPherson, Laura, Wainwright, Elanor N, Liddicoat, Brian, Blyth, Benjamin J, Albertella, Mark R, Rausch, Oliver, Dawson, Mark A
Published in Cancer discovery (07.08.2023)
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Published in Cancer discovery (07.08.2023)
Journal Article
COMBINATION THERAPIES COMPRISING A METTL3 INHIBITOR AND A FURTHER ANTICANCER AGENT
Ofir-Rosenfeld, Yaara, Rausch, Oliver Lars, Albertella, Mark Robert, Vasiliauskaite, Lina
Year of Publication 22.08.2024
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Year of Publication 22.08.2024
Patent
COMBINATION THERAPIES COMPRISING A METTL3 INHIBITOR AND A FURTHER ANTICANCER AGENT
VASILIAUSKAITE, Lina, OFIR-ROSENFELD, Yaara, RAUSCH, Oliver Lars, ALBERTELLA, Mark Robert
Year of Publication 10.04.2024
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Year of Publication 10.04.2024
Patent
COMBINATION THERAPIES COMPRISING A METTL3 INHIBITOR AND A FURTHER ANTICANCER AGENT
VASILIAUSKAITE, Lina, OFIR-ROSENFELD, Yaara, RAUSCH, Oliver Lars, ALBERTELLA, Mark Robert
Year of Publication 04.01.2024
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Year of Publication 04.01.2024
Patent
COMBINATION THERAPIES COMPRISING A METTL3 INHIBITOR AND A FURTHER ANTICANCER AGENT
RAUSCH, OLIVER LARS, VASILIAUSKAITE, LINA, OFIR-ROSENFELD, YAARA, ALBERTELLA, MARK ROBERT
Year of Publication 08.12.2022
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Year of Publication 08.12.2022
Patent
COMBINATION THERAPIES COMPRISING A METTL3 INHIBITOR AND A FURTHER ANTICANCER AGENT
VASILIAUSKAITE, Lina, OFIR-ROSENFELD, Yaara, RAUSCH, Oliver Lars, ALBERTELLA, Mark Robert
Year of Publication 08.12.2022
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Year of Publication 08.12.2022
Patent