Cryptophycins-309, 249 and other cryptophycin analogs: preclinical efficacy studies with mouse and human tumors
Liang, Jian, Moore, Richard E, Moher, Eric D, Munroe, John E, Al-awar, Rima S, Hay, David A, Varie, David L, Zhang, Tony Y, Aikins, James A, Martinelli, Michael J, Shih, Chuan, Ray, James E, Gibson, Lowell L, Vasudevan, Vasu, Polin, Lisa, White, Kathryn, Kushner, Juiwanna, Simpson, Chiab, Pugh, Susan, Corbett, Thomas H
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Published in Investigational new drugs (01.06.2005)
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The synthesis of carbon-14 labeled (R)-4(dipropylamino)-1,3,4,5-tetrahydrobenz[cd]indole-6-carboxamide hippurate. A partial ergoline with 5-HT1A agonist activity and an I-125-labeled analog
Wheeler, WJ, Swanson, SP, Varie, DL, O'Bannon, DD
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Published in Journal of labelled compounds & radiopharmaceuticals (01.02.2005)
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Application of Palladium(0)-Catalyzed Processes to the Synthesis of Oxazole-Containing Partial Ergot Alkaloids
Anderson, Benjamin A, Becke, Lisa M, Booher, Richard N, Flaugh, Michael E, Harn, Nancy K, Kress, Thomas J, Varie, David L, Wepsiec, James P
Published in Journal of organic chemistry (12.12.1997)
Published in Journal of organic chemistry (12.12.1997)
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Synthesis and biological evaluation of cryptophycin analogs with substitution at C-6 (fragment C region)
Varie, David L., Shih, Chuan, Hay, David A., Andis, Sherri L., Corbett, Tom H., Gossett, Lynn S., Janisse, Samantha K., Martinelli, Michael J., Moher, Eric D., Schultz, Richard M., Toth, John E.
Published in Bioorganic & medicinal chemistry letters (08.02.1999)
Published in Bioorganic & medicinal chemistry letters (08.02.1999)
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Bioreduction of ( R)-carvone and regioselective Baeyer-Villiger oxidations: Application to the asymmetric synthesis of cryptophycin fragment A
Varie, David L., Brennan, John, Briggs, Barbara, Cronin, Jason S., Hay, David A., Rieck, John A., Zmijewski, Milton J.
Published in Tetrahedron letters (12.11.1998)
Published in Tetrahedron letters (12.11.1998)
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The synthesis of (S)-di-n-propyl-(8-isoxazol-5-yl-1,2,3,4-tetrahydronaphthalen-2-yl)amine hydrochloride and its C-14-labeled isotopomer
Wheeler, William J., O'Bannon, Douglas D., Swanson, Steven, Gillespie, Todd A., Varie, David L.
Published in Journal of labelled compounds & radiopharmaceuticals (01.02.2005)
Published in Journal of labelled compounds & radiopharmaceuticals (01.02.2005)
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Synthetic studies toward the partial ergot alkaloid LY228729, a potent 5HT(1A) receptor agonist
Carr, MA, Creviston, PE, Hutchison, DR, Kennedy, JH, Khau, VV, Kress, TJ, Leanna, MR, Marshall, JD, Martinelli, MJ, Peterson, BC, Varie, DL, Wepsiec, JP
Published in Journal of organic chemistry (12.12.1997)
Published in Journal of organic chemistry (12.12.1997)
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Thioaldehyde Diels-Alder reactions
Vedejs, E, Eberlein, T. H, Mazur, D. J, McClure, C. K, Perry, D. A, Ruggeri, R, Schwartz, E, Stults, J. S, Varie, D. L
Published in Journal of organic chemistry (01.05.1986)
Published in Journal of organic chemistry (01.05.1986)
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Dienophilic thioaldehydes
Vedejs, E, Eberlein, T. H, Varie, D. L
Published in Journal of the American Chemical Society (01.03.1982)
Published in Journal of the American Chemical Society (01.03.1982)
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Synthetic Studies Towards the Partial Ergot Alkaloid LY228729, a Potent 5HT1a Receptor Agonist
Carr, M. A, Creviston, P. E, Hutchison, D. R, Kennedy, J. H, Khau, V. V, Kress, T. J, Leanna, M. R, Marshall, J. D, Martinelli, Michael J, Peterson, B. C, Varie, D. L, Wepsiec, J. P
Published in Journal of organic chemistry (26.06.1998)
Published in Journal of organic chemistry (26.06.1998)
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THE SYNTHESIS OF (+) AND (-)-1-BENZOYL-1,2,2A,3,4,5-HEXAHYDRO-BENZ[CD]INDOL-4-AMINE, AND PREPARATION OF LY228729
MARTINELLI, MJ, LEANNA, MR, VARIE, DL, PETERSON, BC, KRESS, TJ, WEPSIEC, JP, KHAU, VV
Published in Tetrahedron letters (01.01.1990)
Published in Tetrahedron letters (01.01.1990)
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