The Phe-Phe Motif for Peptide Self-Assembly in Nanomedicine
Get full text
Journal Article
Book Review
Heterochirality and Halogenation Control Phe-Phe Hierarchical Assembly
Kralj, Slavko, Bellotto, Ottavia, Parisi, Evelina, Garcia, Ana M, Iglesias, Daniel, Semeraro, Sabrina, Deganutti, Caterina, D’Andrea, Paola, Vargiu, Attilio V, Geremia, Silvano, De Zorzi, Rita, Marchesan, Silvia
Published in ACS nano (22.12.2020)
Published in ACS nano (22.12.2020)
Get full text
Journal Article
Molecular basis for inhibition of AcrB multidrug efflux pump by novel and powerful pyranopyridine derivatives
Sjuts, Hanno, Vargiu, Attilio V., Kwasny, Steven M., Nguyen, Son T., Kim, Hong-Suk, Ding, Xiaoyuan, Ornik, Alina R., Ruggerone, Paolo, Bowlin, Terry L., Nikaido, Hiroshi, Pos, Klaas M., Opperman, Timothy J.
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (29.03.2016)
Get full text
Journal Article
Binding and Transport of Carboxylated Drugs by the Multidrug Transporter AcrB
Tam, Heng-Keat, Malviya, Viveka N., Foong, Wuen-Ee, Herrmann, Andrea, Malloci, Giuliano, Ruggerone, Paolo, Vargiu, Attilio V., Pos, Klaas M.
Published in Journal of molecular biology (14.02.2020)
Published in Journal of molecular biology (14.02.2020)
Get full text
Journal Article
AcrB drug-binding pocket substitution confers clinically relevant resistance and altered substrate specificity
Blair, Jessica M. A., Bavro, Vassiliy N., Ricci, Vito, Modi, Niraj, Cacciotto, Pierpaolo, Kleinekathӧfer, Ulrich, Ruggerone, Paolo, Vargiu, Attilio V., Baylay, Alison J., Smith, Helen E., Brandon, Yvonne, Galloway, David, Piddock, Laura J. V.
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Published in Proceedings of the National Academy of Sciences - PNAS (17.03.2015)
Get full text
Journal Article
Structural and functional analysis of the promiscuous AcrB and AdeB efflux pumps suggests different drug binding mechanisms
Ornik-Cha, Alina, Wilhelm, Julia, Kobylka, Jessica, Sjuts, Hanno, Vargiu, Attilio V., Malloci, Giuliano, Reitz, Julian, Seybert, Anja, Frangakis, Achilleas S., Pos, Klaas M.
Published in Nature communications (25.11.2021)
Published in Nature communications (25.11.2021)
Get full text
Journal Article
Perturbed structural dynamics underlie inhibition and altered efflux of the multidrug resistance pump AcrB
Reading, Eamonn, Ahdash, Zainab, Fais, Chiara, Ricci, Vito, Wang-Kan, Xuan, Grimsey, Elizabeth, Stone, Jack, Malloci, Giuliano, Lau, Andy M., Findlay, Heather, Konijnenberg, Albert, Booth, Paula J., Ruggerone, Paolo, Vargiu, Attilio V., Piddock, Laura J. V., Politis, Argyris
Published in Nature communications (04.11.2020)
Published in Nature communications (04.11.2020)
Get full text
Journal Article
Chlorpromazine and Amitriptyline Are Substrates and Inhibitors of the AcrB Multidrug Efflux Pump
Grimsey, Elizabeth M, Fais, Chiara, Marshall, Robert L, Ricci, Vito, Ciusa, Maria Laura, Stone, Jack W, Ivens, Alasdair, Malloci, Giuliano, Ruggerone, Paolo, Vargiu, Attilio V, Piddock, Laura J V
Published in mBio (02.06.2020)
Published in mBio (02.06.2020)
Get full text
Journal Article
Identification and characterization of carbapenem binding sites within the RND-transporter AcrB
Atzori, Alessio, Malviya, Viveka N., Malloci, Giuliano, Dreier, Jürg, Pos, Klaas M., Vargiu, Attilio V., Ruggerone, Paolo
Published in Biochimica et biophysica acta. Biomembranes (01.01.2019)
Published in Biochimica et biophysica acta. Biomembranes (01.01.2019)
Get full text
Journal Article
Folding and Self-Assembly of the TatA Translocation Pore Based on a Charge Zipper Mechanism
Walther, Torsten H., Gottselig, Christina, Grage, Stephan L., Wolf, Moritz, Vargiu, Attilio V., Klein, Marco J., Vollmer, Stefanie, Prock, Sebastian, Hartmann, Mareike, Afonin, Sergiy, Stockwald, Eva, Heinzmann, Hartmut, Nolandt, Olga V., Wenzel, Wolfgang, Ruggerone, Paolo, Ulrich, Anne S.
Published in Cell (17.01.2013)
Published in Cell (17.01.2013)
Get full text
Journal Article
Molecular determinants of avoidance and inhibition of Pseudomonas aeruginosa MexB efflux pump
Gervasoni, Silvia, Mehla, Jitender, Bergen, Charles R, Leus, Inga V, Margiotta, Enrico, Malloci, Giuliano, Bosin, Andrea, Vargiu, Attilio V, Lomovskaya, Olga, Rybenkov, Valentin V, Ruggerone, Paolo, Zgurskaya, Helen I
Published in mBio (31.08.2023)
Published in mBio (31.08.2023)
Get full text
Journal Article
Computational modelling of efflux pumps and their inhibitors
Ramaswamy, Venkata Krishnan, Cacciotto, Pierpaolo, Malloci, Giuliano, Vargiu, Attilio V, Ruggerone, Paolo
Published in Essays in biochemistry (03.03.2017)
Published in Essays in biochemistry (03.03.2017)
Get more information
Journal Article
Predictive Rules of Efflux Inhibition and Avoidance in Pseudomonas aeruginosa
Mehla, Jitender, Malloci, Giuliano, Mansbach, Rachael, López, Cesar A, Tsivkovski, Ruslan, Haynes, Keith, Leus, Inga V, Grindstaff, Sally B, Cascella, Robert H, D'Cunha, Napoleon, Herndon, Liam, Hengartner, Nicolas W, Margiotta, Enrico, Atzori, Alessio, Vargiu, Attilio V, Manrique, Pedro D, Walker, John K, Lomovskaya, Olga, Ruggerone, Paolo, Gnanakaran, S, Rybenkov, Valentin V, Zgurskaya, Helen I
Published in mBio (19.01.2021)
Published in mBio (19.01.2021)
Get full text
Journal Article
A Novel Dendrimeric Peptide with Antimicrobial Properties: Structure-Function Analysis of SB056
Scorciapino, Mariano A., Pirri, Giovanna, Vargiu, Attilio V., Ruggerone, Paolo, Giuliani, Andrea, Casu, Mariano, Buerck, Jochen, Wadhwani, Parvesh, Ulrich, Anne S., Rinaldi, Andrea C.
Published in Biophysical journal (07.03.2012)
Published in Biophysical journal (07.03.2012)
Get full text
Journal Article