CAR T-cells that target acute B-lineage leukemia irrespective of CD19 expression
Fousek, Kristen, Watanabe, Junji, Joseph, Sujith K, George, Ann, An, Xingyue, Byrd, Tiara T, Morris, Jessica S, Luong, Annie, Martínez-Paniagua, Melisa A, Sanber, Khaled, Navai, Shoba A, Gad, Ahmed Z, Salsman, Vita S, Mathew, Pretty R, Kim, Hye Na, Wagner, Dimitrios L, Brunetti, Lorenzo, Jang, Albert, Baker, Matthew L, Varadarajan, Navin, Hegde, Meenakshi, Kim, Yong-Mi, Heisterkamp, Nora, Abdel-Azim, Hisham, Ahmed, Nabil
Published in Leukemia (01.01.2021)
Published in Leukemia (01.01.2021)
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Journal Article
High-throughput sequencing of the paired human immunoglobulin heavy and light chain repertoire
DeKosky, Brandon J, Ippolito, Gregory C, Deschner, Ryan P, Lavinder, Jason J, Wine, Yariv, Rawlings, Brandon M, Varadarajan, Navin, Giesecke, Claudia, Dörner, Thomas, Andrews, Sarah F, Wilson, Patrick C, Hunicke-Smith, Scott P, Willson, C Grant, Ellington, Andrew D, Georgiou, George
Published in Nature biotechnology (01.02.2013)
Published in Nature biotechnology (01.02.2013)
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Journal Article
The efficient synthesis and purification of 2′3’- cGAMP from Escherichia coli
Kulkarni, Rohan, Maranholkar, Vijay, Nguyen, Nam, Cirino, Patrick C., Willson, Richard C., Varadarajan, Navin
Published in Frontiers in microbiology (08.03.2024)
Published in Frontiers in microbiology (08.03.2024)
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Journal Article
Multifaceted Role of BTLA in the Control of CD8 + T-cell Fate after Antigen Encounter
Ritthipichai, Krit, Haymaker, Cara L, Martinez, Melisa, Aschenbrenner, Andrew, Yi, Xiaohui, Zhang, Minying, Kale, Charuta, Vence, Luis M, Roszik, Jason, Hailemichael, Yared, Overwijk, Willem W, Varadarajan, Navin, Nurieva, Roza, Radvanyi, Laszlo G, Hwu, Patrick, Bernatchez, Chantale
Published in Clinical cancer research (15.10.2017)
Published in Clinical cancer research (15.10.2017)
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Journal Article
CD8 + T cells inhibit metastasis and CXCL4 regulates its function
Joseph, Robiya, Soundararajan, Rama, Vasaikar, Suhas, Yang, Fei, Allton, Kendra L, Tian, Lin, den Hollander, Petra, Isgandarova, Sevinj, Haemmerle, Monika, Mino, Barbara, Zhou, Tieling, Shin, Crystal, Martinez-Paniagua, Melisa, Sahin, Aysegul A, Rodriguez-Canales, Jaime, Gelovani, Juri, Chang, Jeffrey T, Acharya, Ghanashyam, Sood, Anil K, Wistuba, Ignacio I, Gibbons, Don L, Solis, Luisa M, Barton, Michelle C, Varadarajan, Navin, Rosen, Jeffrey M, Zhang, Xiang H, Mani, Sendurai A
Published in British journal of cancer (20.07.2021)
Published in British journal of cancer (20.07.2021)
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Journal Article
Multidimensional single-cell analysis identifies a role for CD2-CD58 interactions in clinical antitumor T cell responses
Romain, Gabrielle, Strati, Paolo, Rezvan, Ali, Fathi, Mohsen, Bandey, Irfan N, Adolacion, Jay R.T, Heeke, Darren, Liadi, Ivan, Marques-Piubelli, Mario L, Solis, Luisa M, Mahendra, Ankit, Vega, Francisco, Cooper, Laurence J.N, Singh, Harjeet, Mattie, Mike, Bot, Adrian, Neelapu, Sattva S, Varadarajan, Navin
Published in The Journal of clinical investigation (01.09.2022)
Published in The Journal of clinical investigation (01.09.2022)
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Journal Article
Cytotoxic T lymphocytes targeting a conserved SARS-CoV-2 spike epitope are efficient serial killers
Fathi, Mohsen, Charley, Lindsey, Cooper, Laurence Jn, Varadarajan, Navin, Meyer, Daniel D
Published in BioTechniques (01.04.2022)
Published in BioTechniques (01.04.2022)
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Journal Article
Single-cell profiling of dynamic cytokine secretion and the phenotype of immune cells
An, Xingyue, Sendra, Victor G, Liadi, Ivan, Ramesh, Balakrishnan, Romain, Gabrielle, Haymaker, Cara, Martinez-Paniagua, Melisa, Lu, Yanbin, Radvanyi, Laszlo G, Roysam, Badrinath, Varadarajan, Navin
Published in PloS one (24.08.2017)
Published in PloS one (24.08.2017)
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Journal Article
Single-dose intranasal vaccination elicits systemic and mucosal immunity against SARS-CoV-2
An, Xingyue, Martinez-Paniagua, Melisa, Rezvan, Ali, Sefat, Samiur Rahman, Fathi, Mohsen, Singh, Shailbala, Biswas, Sujit, Pourpak, Melissa, Yee, Cassian, Liu, Xinli, Varadarajan, Navin
Published in iScience (24.09.2021)
Published in iScience (24.09.2021)
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Journal Article
Multi-antigen intranasal vaccine protects against challenge with sarbecoviruses and prevents transmission in hamsters
Leekha, Ankita, Saeedi, Arash, Sefat, K M Samiur Rahman, Kumar, Monish, Martinez-Paniagua, Melisa, Damian, Adrian, Kulkarni, Rohan, Reichel, Kate, Rezvan, Ali, Masoumi, Shalaleh, Liu, Xinli, Cooper, Laurence J. N., Sebastian, Manu, Sands, Courtney M., Das, Vallabh E., Patel, Nimesh B., Hurst, Brett, Varadarajan, Navin
Published in Nature communications (23.07.2024)
Published in Nature communications (23.07.2024)
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Journal Article
An intranasal nanoparticle STING agonist protects against respiratory viruses in animal models
Leekha, Ankita, Saeedi, Arash, Kumar, Monish, Sefat, K. M. Samiur Rahman, Martinez-Paniagua, Melisa, Meng, Hui, Fathi, Mohsen, Kulkarni, Rohan, Reichel, Kate, Biswas, Sujit, Tsitoura, Daphne, Liu, Xinli, Cooper, Laurence J. N., Sands, Courtney M., Das, Vallabh E., Sebastian, Manu, Hurst, Brett L., Varadarajan, Navin
Published in Nature communications (18.07.2024)
Published in Nature communications (18.07.2024)
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Journal Article
Targeting the Interplay between Epithelial-to-Mesenchymal-Transition and the Immune System for Effective Immunotherapy
Soundararajan, Rama, Fradette, Jared J, Konen, Jessica M, Moulder, Stacy, Zhang, Xiang, Gibbons, Don L, Varadarajan, Navin, Wistuba, Ignacio I, Tripathy, Debasish, Bernatchez, Chantale, Byers, Lauren A, Chang, Jeffrey T, Contreras, Alejandro, Lim, Bora, Parra, Edwin Roger, Roarty, Emily B, Wang, Jing, Yang, Fei, Barton, Michelle, Rosen, Jeffrey M, Mani, Sendurai A
Published in Cancers (24.05.2019)
Published in Cancers (24.05.2019)
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Journal Article
A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens
Yankaskas, Christopher L, Thompson, Keyata N, Paul, Colin D, Vitolo, Michele I, Mistriotis, Panagiotis, Mahendra, Ankit, Bajpai, Vivek K, Shea, Daniel J, Manto, Kristen M, Chai, Andreas C, Varadarajan, Navin, Kontrogianni-Konstantopoulos, Aikaterini, Martin, Stuart S, Konstantopoulos, Konstantinos
Published in Nature biomedical engineering (01.06.2019)
Published in Nature biomedical engineering (01.06.2019)
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Journal Article
Decoding the mechanisms of chimeric antigen receptor (CAR) T cell-mediated killing of tumors: insights from granzyme and Fas inhibition
Montalvo, Melisa J, Bandey, Irfan N, Rezvan, Ali, Wu, Kwan-Ling, Saeedi, Arash, Kulkarni, Rohan, Li, Yongshuai, An, Xingyue, Sefat, K M Samiur Rahman, Varadarajan, Navin
Published in Cell death & disease (02.02.2024)
Published in Cell death & disease (02.02.2024)
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Journal Article
Rapid, efficient functional characterization and recovery of HIV-specific human CD8+ T cells using microengraving
Varadarajan, Navin, Kwon, Douglas S, Law, Kenneth M, Ogunniyi, Adebola O, Anahtar, Melis N, Richter, James M, Walker, Bruce D, Love, J. Christopher
Published in Proceedings of the National Academy of Sciences - PNAS (06.03.2012)
Published in Proceedings of the National Academy of Sciences - PNAS (06.03.2012)
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Journal Article
Single-Cell Cloning of Breast Cancer Cells Secreting Specific Subsets of Extracellular Vesicles
Fathi, Mohsen, Joseph, Robiya, Adolacion, Jay R T., Martinez-Paniagua, Melisa, An, Xingyue, Gabrusiewicz, Konrad, Mani, Sendurai A., Varadarajan, Navin
Published in Cancers (31.08.2021)
Published in Cancers (31.08.2021)
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Journal Article
Phasetime: Deep Learning Approach to Detect Nuclei in Time Lapse Phase Images
Yuan, Pengyu, Rezvan, Ali, Li, Xiaoyang, Varadarajan, Navin, Van Nguyen, Hien
Published in Journal of clinical medicine (02.08.2019)
Published in Journal of clinical medicine (02.08.2019)
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Journal Article
Defining potency of CAR+ T cells: Fast and furious or slow and steady
Liadi, Ivan, Singh, Harjeet, Romain, Gabrielle, Roysam, Badrinath, Cooper, Laurence JN, Varadarajan, Navin
Published in Oncoimmunology (03.10.2019)
Published in Oncoimmunology (03.10.2019)
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