Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N'-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R,3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine(2A) receptor inverse agonist
Vanover, Kimberly E, Weiner, David M, Makhay, Malath, Veinbergs, Isaac, Gardell, Luis R, Lameh, Jelveh, Del Tredici, Andria L, Piu, Fabrice, Schiffer, Hans H, Ott, Thomas R, Burstein, Ethan S, Uldam, Allan K, Thygesen, Mikkel B, Schlienger, Nathalie, Andersson, Carl Magnus, Son, Thomas Y, Harvey, Scott C, Powell, Susan B, Geyer, Mark A, Tolf, Bo-Ragner, Brann, Mark R, Davis, Robert E
Published in The Journal of pharmacology and experimental therapeutics (01.05.2006)
Published in The Journal of pharmacology and experimental therapeutics (01.05.2006)
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Journal Article
The role of M1 muscarinic receptor agonism of N-desmethylclozapine in the unique clinical effects of clozapine
WEINER, D. M, MELTZER, H. Y, VANOVER, K. E, OLSSON, R, JAYATHILAKE, K, LEE, M, LEVEY, A. I, HACKSELL, U, BURSTEIN, E. S, DAVIS, R. E, BRANN, M. R, VEINBERGS, I, DONOHUE, E. M, SPALDING, T. A, SMITH, T. T, MOHELL, N, HARVEY, S. C, LAMEH, J, NASH, N
Published in Psychopharmacologia (01.12.2004)
Published in Psychopharmacologia (01.12.2004)
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Journal Article
PET analysis of the 5-HT2A receptor inverse agonist ACP-103 in human brain
Nordstrom, Anna-Lena, Mansson, Mattias, Jovanovic, Hristina, Karlsson, Per, Halldin, Christer, Farde, Lars, Vanover, Kimberly E., Hacksell, Uli, Brann, Mark R., Davis, Robert E., Weiner, David M.
Published in The international journal of neuropsychopharmacology (01.03.2008)
Published in The international journal of neuropsychopharmacology (01.03.2008)
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Journal Article
A 5-HT sub(2) sub(A) receptor inverse agonist, ACP-103, reduces tremor in a rat model and levodopa-induced dyskinesias in a monkey model
Vanover, KE, Betz, A J, Weber, S M, Bibbiani, F, Kielaite, A, Weiner, D M, Davis, R E, Chase, T N, Salamone, J D
Published in Pharmacology, biochemistry and behavior (01.10.2008)
Published in Pharmacology, biochemistry and behavior (01.10.2008)
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Journal Article
PET analysis of the 5-HT 2A receptor inverse agonist ACP-103 in human brain
Nordstrom, A-L, Mansson, M, Jovanovic, H, Karlsson, P, Halldin, C, Farde, L, Vanover, KE, Hacksell, U, Brann, MR, Davis, RE
Published in The international journal of neuropsychopharmacology (2008)
Published in The international journal of neuropsychopharmacology (2008)
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Journal Article
Pharmacological Characterization of AC-90179 [2-(4-Methoxyphenyl)-N-(4-methyl-benzyl)-N-(1-methyl-piperidin-4-yl)-acetamide Hydrochloride]: A Selective Serotonin 2A Receptor Inverse Agonist
Vanover, Kimberly E, Harvey, Scott C, Son, Thomas, Bradley, Stefania Risso, Kold, Henriette, Makhay, Malath, Veinbergs, Isaac, Spalding, Tracy A, Weiner, David M, Andersson, Carl Magnus, Tolf, Bo-Ragnar, Brann, Mark R, Hacksell, Uli, Davis, Robert E
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
Published in The Journal of pharmacology and experimental therapeutics (01.09.2004)
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Journal Article
Positive allosteric modulators of the GABA(A) receptor: differential interaction of benzodiazepines and neuroactive steroids with ethanol
Vanover, K E, Suruki, M, Robledo, S, Huber, M, Wieland, S, Lan, N C, Gee, K W, Wood, P L, Carter, R B
Published in Psychopharmacology (01.01.1999)
Published in Psychopharmacology (01.01.1999)
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Journal Article
Characterization of the anxiolytic properties of a novel neuroactive steroid, Co 2-6749 (GMA-839; WAY-141839; 3alpha, 21-dihydroxy-3beta-trifluoromethyl-19-nor-5beta-pregnan-20-one), a selective modulator of gamma-aminobutyric acid(A) receptors
Vanover, K E, Rosenzweig-Lipson, S, Hawkinson, J E, Lan, N C, Belluzzi, J D, Stein, L, Barrett, J E, Wood, P L, Carter, R B
Published in The Journal of pharmacology and experimental therapeutics (01.10.2000)
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Published in The Journal of pharmacology and experimental therapeutics (01.10.2000)
Journal Article
ITI-007: A Novel Treatment for Sleep Disorders and Dyskinesia in Parkinson's Disease
Vanover, KE, Davis, RE, Snyder, GL, Hendrick, JP, Fisone, G, Fienberg, AA, Wennogle, LP, Mates, S
Published in MOVEMENT DISORDERS (2010)
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Published in MOVEMENT DISORDERS (2010)
Conference Proceeding
Behavioral characterization of Co 134444 (3 alpha -hydroxy-21-(1'-imidazolyl)-3 beta -methoxymethyl-5 alpha -pregnan-20-on e), a novel sedative-hypnotic neuroactive steroid
Vanover, KE, Hogenkamp, D J, Lan, N C, Gee, K W, Carter, R B
Published in Psychopharmacology (25.05.2001)
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Published in Psychopharmacology (25.05.2001)
Journal Article
Development of Novel PDE1 Inhibitors as Dose-Sparing Medications in Parkinson's Disease
Snyder, GL, Vanover, KE, Zhu, H, Zhang, L, Li, P, Hendrick, JP, Fisone, G, Davis, RE, Fienberg, AA, Wennogle, LP, Mates, S
Published in MOVEMENT DISORDERS (2010)
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Published in MOVEMENT DISORDERS (2010)
Conference Proceeding