Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders
Spaas, Jan, van Veggel, Lieve, Schepers, Melissa, Tiane, Assia, van Horssen, Jack, Wilson, David M., Moya, Pablo R., Piccart, Elisabeth, Hellings, Niels, Eijnde, Bert O., Derave, Wim, Schreiber, Rudy, Vanmierlo, Tim
Published in Cellular and molecular life sciences : CMLS (01.05.2021)
Published in Cellular and molecular life sciences : CMLS (01.05.2021)
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Journal Article
DNA methylation regulates the expression of the negative transcriptional regulators ID2 and ID4 during OPC differentiation
Tiane, Assia, Schepers, Melissa, Riemens, Renzo, Rombaut, Ben, Vandormael, Patrick, Somers, Veerle, Prickaerts, Jos, Hellings, Niels, van den Hove, Daniel, Vanmierlo, Tim
Published in Cellular and molecular life sciences : CMLS (01.10.2021)
Published in Cellular and molecular life sciences : CMLS (01.10.2021)
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Journal Article
The PDE4 inhibitor roflumilast improves memory in rodents at non-emetic doses
Vanmierlo, Tim, Creemers, Pim, Akkerman, Sven, van Duinen, Marlies, Sambeth, Anke, De Vry, Jochen, Uz, Tolga, Blokland, Arjan, Prickaerts, Jos
Published in Behavioural brain research (15.04.2016)
Published in Behavioural brain research (15.04.2016)
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Journal Article
Dietary Sargassum fusiforme improves memory and reduces amyloid plaque load in an Alzheimer’s disease mouse model
Bogie, Jeroen, Hoeks, Cindy, Schepers, Melissa, Tiane, Assia, Cuypers, Ann, Leijten, Frank, Chintapakorn, Yupyn, Suttiyut, Thiti, Pornpakakul, Surachai, Struik, Dicky, Kerksiek, Anja, Liu, Hong-Bing, Hellings, Niels, Martinez-Martinez, Pilar, Jonker, Johan W., Dewachter, Ilse, Sijbrands, Eric, Walter, Jochen, Hendriks, Jerome, Groen, Albert, Staels, Bart, Lütjohann, Dieter, Vanmierlo, Tim, Mulder, Monique
Published in Scientific reports (20.03.2019)
Published in Scientific reports (20.03.2019)
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Journal Article
Unleashing Spinal Cord Repair: The Role of cAMP-Specific PDE Inhibition in Attenuating Neuroinflammation and Boosting Regeneration after Traumatic Spinal Cord Injury
Mussen, Femke, Broeckhoven, Jana Van, Hellings, Niels, Schepers, Melissa, Vanmierlo, Tim
Published in International journal of molecular sciences (02.05.2023)
Published in International journal of molecular sciences (02.05.2023)
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Journal Article
Insights from an academic endeavor into central nervous system drug discovery
van Veggel, Lieve, Voets, An M, Vanmierlo, Tim, Schreiber, Rudy
Published in Neural regeneration research (01.06.2025)
Published in Neural regeneration research (01.06.2025)
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Journal Article
Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?
Nelissen, Ellis, Schepers, Melissa, Ponsaerts, Laura, Foulquier, Sébastien, Bronckaers, Annelies, Vanmierlo, Tim, Sandner, Peter, Prickaerts, Jos
Published in Pharmacological research (01.11.2023)
Published in Pharmacological research (01.11.2023)
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Journal Article
From OPC to Oligodendrocyte: An Epigenetic Journey
Tiane, Assia, Schepers, Melissa, Rombaut, Ben, Hupperts, Raymond, Prickaerts, Jos, Hellings, Niels, van den Hove, Daniel, Vanmierlo, Tim
Published in Cells (Basel, Switzerland) (11.10.2019)
Published in Cells (Basel, Switzerland) (11.10.2019)
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Journal Article
Oncostatin M-induced astrocytic tissue inhibitor of metalloproteinases-1 drives remyelination
Houben, Evelien, Janssens, Kris, Hermans, Doryssa, Vandooren, Jennifer, Van den Haute, Chris, Schepers, Melissa, Vanmierlo, Tim, Lambrichts, Ivo, van Horssen, Jack, Baekelandt, Veerle, Opdenakker, Ghislain, Baron, Wia, Broux, Bieke, Slaets, Helena, Hellings, Niels
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.2020)
Published in Proceedings of the National Academy of Sciences - PNAS (03.03.2020)
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Journal Article
Sphingosine-1-Phosphate Receptor Modulators and Oligodendroglial Cells: Beyond Immunomodulation
Roggeri, Alessandra, Schepers, Melissa, Tiane, Assia, Rombaut, Ben, van Veggel, Lieve, Hellings, Niels, Prickaerts, Jos, Pittaluga, Anna, Vanmierlo, Tim
Published in International journal of molecular sciences (13.10.2020)
Published in International journal of molecular sciences (13.10.2020)
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Journal Article
Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion
Santiago, Amanda, Soares, Lígia Mendes, Schepers, Melissa, Milani, Humberto, Vanmierlo, Tim, Prickaerts, Jos, Weffort de Oliveira, Rúbia M.
Published in Neuropharmacology (01.08.2018)
Published in Neuropharmacology (01.08.2018)
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Journal Article
Amelioration of functional and histopathological consequences after spinal cord injury through phosphodiesterase 4D (PDE4D) inhibition
Schepers, Melissa, Hendrix, Sven, Mussen, Femke, van Breedam, Elise, Ponsaerts, Peter, Lemmens, Stefanie, Hellings, Niels, Ricciarelli, Roberta, Fedele, Ernesto, Bruno, Olga, Brullo, Chiara, Prickaerts, Jos, Van Broeckhoven, Jana, Vanmierlo, Tim
Published in Neurotherapeutics (01.07.2024)
Published in Neurotherapeutics (01.07.2024)
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Journal Article
The Impact of Sample Storage on Blood Methylation: Towards Assessing Myelin Gene Methylation as a Biomarker for Progressive Multiple Sclerosis
Tiane, Assia, Somers, Veerle, Hellings, Niels, van den Hove, Daniel L A, Vanmierlo, Tim
Published in International journal of molecular sciences (01.03.2024)
Published in International journal of molecular sciences (01.03.2024)
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Journal Article
Beyond PDE4 inhibition: A comprehensive review on downstream cAMP signaling in the central nervous system
Donders, Zoë, Skorupska, Iga Joanna, Willems, Emily, Mussen, Femke, Broeckhoven, Jana Van, Carlier, Aurélie, Schepers, Melissa, Vanmierlo, Tim
Published in Biomedicine & pharmacotherapy (01.08.2024)
Published in Biomedicine & pharmacotherapy (01.08.2024)
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Journal Article
Presynaptic Release-Regulating Sphingosine 1-Phosphate 1/3 Receptors in Cortical Glutamatergic Terminals: Adaptations in EAE Mice and Impact of Therapeutic FTY720
Roggeri, Alessandra, Olivero, Guendalina, Usai, Cesare, Vanmierlo, Tim, Pittaluga, Anna
Published in Cells (Basel, Switzerland) (24.09.2023)
Published in Cells (Basel, Switzerland) (24.09.2023)
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Journal Article
Brown Seaweed Food Supplementation: Effects on Allergy and Inflammation and Its Consequences
Olsthoorn, Simone E. M, Wang, Xi, Tillema, Berend, Vanmierlo, Tim, Kraan, Stefan, Leenen, Pieter J. M, Mulder, Monique T
Published in Nutrients (29.07.2021)
Published in Nutrients (29.07.2021)
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Journal Article
Editorial: Cyclic Nucleotide Phosphodiesterases (PDEs) in Immune Regulation and Inflammation
Brocke, Stefan, Epstein, Paul M., Nelson, Robert, Vanmierlo, Tim
Published in Frontiers in pharmacology (06.07.2022)
Published in Frontiers in pharmacology (06.07.2022)
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Journal Article
Editorial: Neuro-Immune Connections to Enable Repair in CNS Disorders
Vanmierlo, Tim, van Horssen, Jack, Hellings, Niels, Broux, Bieke
Published in Frontiers in immunology (24.07.2020)
Published in Frontiers in immunology (24.07.2020)
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Journal Article