Differential susceptibility of retinal ganglion cell subtypes in acute and chronic models of injury and disease
VanderWall, Kirstin B., Lu, Bin, Alfaro, Jorge S., Allsop, Anna R., Carr, Alexa S., Wang, Shaomei, Meyer, Jason S.
Published in Scientific reports (15.10.2020)
Published in Scientific reports (15.10.2020)
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Journal Article
Acquisition of neurodegenerative features in isogenic OPTN(E50K) human stem cell-derived retinal ganglion cells associated with autophagy disruption and mTORC1 signaling reduction
Huang, Kang-Chieh, Gomes, Cátia, Shiga, Yukihiro, Belforte, Nicolas, VanderWall, Kirstin B, Lavekar, Sailee S, Fligor, Clarisse M, Harkin, Jade, Hetzer, Shelby M, Patil, Shruti V, Di Polo, Adriana, Meyer, Jason S
Published in Acta neuropathologica communications (18.10.2024)
Published in Acta neuropathologica communications (18.10.2024)
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Journal Article
Astrocytes Regulate the Development and Maturation of Retinal Ganglion Cells Derived from Human Pluripotent Stem Cells
VanderWall, Kirstin B., Vij, Ridhima, Ohlemacher, Sarah K., Sridhar, Akshayalakshmi, Fligor, Clarisse M., Feder, Elyse M., Edler, Michael C., Baucum, Anthony J., Cummins, Theodore R., Meyer, Jason S.
Published in Stem cell reports (12.02.2019)
Published in Stem cell reports (12.02.2019)
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Journal Article
Extension of retinofugal projections in an assembled model of human pluripotent stem cell-derived organoids
Fligor, Clarisse M., Lavekar, Sailee S., Harkin, Jade, Shields, Priya K., VanderWall, Kirstin B., Huang, Kang-Chieh, Gomes, Cátia, Meyer, Jason S.
Published in Stem cell reports (14.09.2021)
Published in Stem cell reports (14.09.2021)
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Journal Article
Retinal Ganglion Cells With a Glaucoma OPTN(E50K) Mutation Exhibit Neurodegenerative Phenotypes when Derived from Three-Dimensional Retinal Organoids
VanderWall, Kirstin B., Huang, Kang-Chieh, Pan, Yanling, Lavekar, Sailee S., Fligor, Clarisse M., Allsop, Anna R., Lentsch, Kelly A., Dang, Pengtao, Zhang, Chi, Tseng, Henry C., Cummins, Theodore R., Meyer, Jason S.
Published in Stem cell reports (14.07.2020)
Published in Stem cell reports (14.07.2020)
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Journal Article
Quantitative Measurement of Cytosolic and Nuclear Penetration of Oligonucleotide Therapeutics
Deprey, Kirsten, Batistatou, Nefeli, Debets, Marjoke F, Godfrey, Jack, VanderWall, Kirstin B, Miles, Rebecca R, Shehaj, Livia, Guo, Jiaxing, Andreucci, Amy, Kandasamy, Pachamuthu, Lu, Genliang, Shimizu, Mamoru, Vargeese, Chandra, Kritzer, Joshua A
Published in ACS chemical biology (18.02.2022)
Published in ACS chemical biology (18.02.2022)
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Journal Article
Astrocytes modulate neurodegenerative phenotypes associated with glaucoma in OPTN(E50K) human stem cell-derived retinal ganglion cells
Gomes, Cátia, VanderWall, Kirstin B, Pan, Yanling, Lu, Xiaoyu, Lavekar, Sailee S, Huang, Kang-Chieh, Fligor, Clarisse M, Harkin, Jade, Zhang, Chi, Cummins, Theodore R, Meyer, Jason S
Published in Stem cell reports (12.07.2022)
Published in Stem cell reports (12.07.2022)
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Journal Article
Induction of astrocyte reactivity promotes neurodegeneration in human pluripotent stem cell models
Gomes, Cátia, Huang, Kang-Chieh, Harkin, Jade, Baker, Aaron, Hughes, Jason M., Pan, Yanling, Tutrow, Kaylee, VanderWall, Kirstin B., Lavekar, Sailee S., Hernandez, Melody, Cummins, Theodore R., Canfield, Scott G., Meyer, Jason S.
Published in Stem cell reports (13.08.2024)
Published in Stem cell reports (13.08.2024)
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Journal Article
Autophagy Disruption Reduces mTORC1 Activation Leading to Retinal Ganglion Cell Neurodegeneration Associated with Glaucoma
Kang-Chieh Huang, Gomes, Cítia, Shiga, Yukihiro, Belforte, Nicolas, Vanderwall, Kirstin B, Lavekar, Sailee S, Fligor, Clarisse M, Harkin, Jade, Adriana Di Polo, Meyer, Jason S
Published in bioRxiv (04.01.2023)
Published in bioRxiv (04.01.2023)
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Paper
Acquisition of neurodegenerative features in isogenic OPTN
Shiga, Yukihiro, Lavekar, Sailee S, Patil, Shruti V, Meyer, Jason S, Huang, Kang-Chieh, Di Polo, Adriana, Gomes, Cátia, Belforte, Nicolas, Fligor, Clarisse M, Harkin, Jade, Hetzer, Shelby M, VanderWall, Kirstin B
Published in Acta neuropathologica communications (18.10.2024)
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Published in Acta neuropathologica communications (18.10.2024)
Journal Article
Autophagy disruption reduces mTORC1 activation leading to retinal ganglion cell neurodegeneration associated with glaucoma
Huang, Kang-Chieh, Gomes, Cátia, Shiga, Yukihiro, Belforte, Nicolas, VanderWall, Kirstin B, Lavekar, Sailee S, Fligor, Clarisse M, Harkin, Jade, Di Polo, Adriana, Meyer, Jason S
Published in bioRxiv : the preprint server for biology (04.01.2023)
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Published in bioRxiv : the preprint server for biology (04.01.2023)
Journal Article
Retinal ganglion cells harboring the OPTN(E50K) glaucoma mutation exhibit neurodegenerative phenotypes when derived from hPSC-derived three dimensional retinal organoids
Vanderwall, Kirstin B, Kang-Chieh Huang, Pan, Yanling, Lavekar, Sailee S, Fligor, Clarisse M, Allsop, Anna, Lentsch, Kelly A, Dang, Pengtao, Zhang, Chi, Tseng, Henry, Cummins, Theodore R, Meyer, Jason
Published in bioRxiv (29.10.2019)
Published in bioRxiv (29.10.2019)
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