Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation
Di Niro, Roberto, Lee, Seung-Joo, Vander Heiden, Jason A., Elsner, Rebecca A., Trivedi, Nikita, Bannock, Jason M., Gupta, Namita T., Kleinstein, Steven H., Vigneault, Francois, Gilbert, Tamara J., Meffre, Eric, McSorley, Stephen J., Shlomchik, Mark J.
Published in Immunity (Cambridge, Mass.) (21.07.2015)
Published in Immunity (Cambridge, Mass.) (21.07.2015)
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Journal Article
Individual heritable differences result in unique cell lymphocyte receptor repertoires of naïve and antigen-experienced cells
Rubelt, Florian, Bolen, Christopher R, McGuire, Helen M, Vander Heiden, Jason A, Gadala-Maria, Daniel, Levin, Mikhail, Euskirchen, Ghia M, Mamedov, Murad R, Swan, Gary E, Dekker, Cornelia L, Cowell, Lindsay G, Kleinstein, Steven H, Davis, Mark M
Published in Nature communications (23.03.2016)
Published in Nature communications (23.03.2016)
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Journal Article
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
Sun, Tianhe, Huang, Zhiyu, Liang, Wei-Ching, Yin, Jianping, Lin, Wei Yu, Wu, Jia, Vernes, Jean-Michel, Lutman, Jeff, Caplazi, Patrick, Jeet, Surinder, Wong, Tiffany, Wong, Manda, DePianto, Daryle J, Morshead, Katrina B, Sun, Kai-Hui, Modrusan, Zora, Vander Heiden, Jason A, Abbas, Alexander R, Zhang, Hua, Xu, Min, N'Diaye, Elsa-Noah, Roose-Girma, Meron, Wolters, Paul J, Yadav, Rajbharan, Sukumaran, Siddharth, Ghilardi, Nico, Corpuz, Racquel, Emson, Claire, Meng, Y Gloria, Ramalingam, Thirumalai R, Lupardus, Patrick, Brightbill, Hans D, Seshasayee, Dhaya, Wu, Yan, Arron, Joseph R
Published in Science translational medicine (04.08.2021)
Published in Science translational medicine (04.08.2021)
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Journal Article
Dysregulation of B Cell Repertoire Formation in Myasthenia Gravis Patients Revealed through Deep Sequencing
Vander Heiden, Jason A, Stathopoulos, Panos, Zhou, Julian Q, Chen, Luan, Gilbert, Tamara J, Bolen, Christopher R, Barohn, Richard J, Dimachkie, Mazen M, Ciafaloni, Emma, Broering, Teresa J, Vigneault, Francois, Nowak, Richard J, Kleinstein, Steven H, O'Connor, Kevin C
Published in The Journal of immunology (1950) (15.02.2017)
Published in The Journal of immunology (1950) (15.02.2017)
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Journal Article
High-resolution antibody dynamics of vaccine-induced immune responses
Laserson, Uri, Vigneault, Francois, Gadala-Maria, Daniel, Yaari, Gur, Uduman, Mohamed, Heiden, Jason A. Vander, Kelton, William, Jung, Sang Taek, Liu, Yi, Laserson, Jonathan, Chari, Raj, Lee, Je-Hyuk, Bachelet, Ido, Hickey, Brendan, Lieberman-Aiden, Erez, Hanczaruk, Bozena, Simen, Birgitte B., Egholm, Michael, Koller, Daphne, Georgiou, George, Kleinstein, Steven H., Church, George M.
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.2014)
Published in Proceedings of the National Academy of Sciences - PNAS (01.04.2014)
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Journal Article
pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires
Vander Heiden, Jason A, Yaari, Gur, Uduman, Mohamed, Stern, Joel N H, O'Connor, Kevin C, Hafler, David A, Vigneault, Francois, Kleinstein, Steven H
Published in Bioinformatics (Oxford, England) (01.07.2014)
Published in Bioinformatics (Oxford, England) (01.07.2014)
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Journal Article
B cells populating the multiple sclerosis brain mature in the draining cervical lymph nodes
Stern, Joel N H, Yaari, Gur, Vander Heiden, Jason A, Church, George, Donahue, William F, Hintzen, Rogier Q, Huttner, Anita J, Laman, Jon D, Nagra, Rashed M, Nylander, Alyssa, Pitt, David, Ramanan, Sriram, Siddiqui, Bilal A, Vigneault, Francois, Kleinstein, Steven H, Hafler, David A, O'Connor, Kevin C
Published in Science translational medicine (06.08.2014)
Published in Science translational medicine (06.08.2014)
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Journal Article
Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination
Hoehn, Kenneth B., Vander Heiden, Jason A., Zhou, Julian Q., Lunter, Gerton, Pybus, Oliver G., Kleinstein, Steven H.
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (05.11.2019)
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Journal Article
Reproducibility and Reuse of Adaptive Immune Receptor Repertoire Data
Breden, Felix, Luning Prak, Eline T, Peters, Bjoern, Rubelt, Florian, Schramm, Chaim A, Busse, Christian E, Vander Heiden, Jason A, Christley, Scott, Bukhari, Syed Ahmad Chan, Thorogood, Adrian, Matsen Iv, Frederick A, Wine, Yariv, Laserson, Uri, Klatzmann, David, Douek, Daniel C, Lefranc, Marie-Paule, Collins, Andrew M, Bubela, Tania, Kleinstein, Steven H, Watson, Corey T, Cowell, Lindsay G, Scott, Jamie K, Kepler, Thomas B
Published in Frontiers in immunology (01.11.2017)
Published in Frontiers in immunology (01.11.2017)
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Journal Article
Molecular mapping of interstitial lung disease reveals a phenotypically distinct senescent basal epithelial cell population
DePianto, Daryle J, Heiden, Jason A Vander, Morshead, Katrina B, Sun, Kai-Hui, Modrusan, Zora, Teng, Grace, Wolters, Paul J, Arron, Joseph R
Published in JCI insight (22.04.2021)
Published in JCI insight (22.04.2021)
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Journal Article
The Repertoire Dissimilarity Index as a method to compare lymphocyte receptor repertoires
Bolen, Christopher R, Rubelt, Florian, Vander Heiden, Jason A, Davis, Mark M
Published in BMC bioinformatics (07.03.2017)
Published in BMC bioinformatics (07.03.2017)
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Journal Article
Interleukin-10 from CD4 + follicular regulatory T cells promotes the germinal center response
Laidlaw, Brian J, Lu, Yisi, Amezquita, Robert A, Weinstein, Jason S, Vander Heiden, Jason A, Gupta, Namita T, Kleinstein, Steven H, Kaech, Susan M, Craft, Joe
Published in Science immunology (20.10.2017)
Published in Science immunology (20.10.2017)
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Journal Article
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis
Xi, Ying, LaCanna, Ryan, Ma, Hsiao-Yen, N’Diaye, Elsa-Noah, Gierke, Sarah, Caplazi, Patrick, Sagolla, Meredith, Huang, Zhiyu, Lucio, Laura, Arlantico, Alexander, Jeet, Surinder, Brightbill, Hans, Emson, Claire, Wong, Aaron, Morshead, Katrina B., DePianto, Daryle J., Roose-Girma, Merone, Yu, Charles, Tam, Lucinda, Jia, Guiquan, Ramalingam, Thirumalai R., Marsters, Scot, Ashkenazi, Avi, Kim, Si Hyun, Kelly, Ryan, Wu, Shuang, Wolters, Paul J., Feldstein, Ariel E., Vander Heiden, Jason A., Ding, Ning
Published in Cell metabolism (06.09.2022)
Published in Cell metabolism (06.09.2022)
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Journal Article
In vivo partial reprogramming alters age-associated molecular changes during physiological aging in mice
Browder, Kristen C, Reddy, Pradeep, Yamamoto, Mako, Haghani, Amin, Guillen, Isabel Guillen, Sahu, Sanjeeb, Wang, Chao, Luque, Yosu, Prieto, Javier, Shi, Lei, Shojima, Kensaku, Hishida, Tomoaki, Lai, Zijuan, Li, Qingling, Choudhury, Feroza K, Wong, Weng R, Liang, Yuxin, Sangaraju, Dewakar, Sandoval, Wendy, Esteban, Concepcion Rodriguez, Delicado, Estrella Nuñez, Garcia, Pedro Guillen, Pawlak, Michal, Vander Heiden, Jason A, Horvath, Steve, Jasper, Heinrich, Izpisua Belmonte, Juan Carlos
Published in Nature aging (01.03.2022)
Published in Nature aging (01.03.2022)
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Journal Article
Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis
Wu, Yu-Chang B., PhD, James, Louisa K., PhD, Vander Heiden, Jason A., MSc, Uduman, Mohamed, PhD, Durham, Stephen R., MD, FRCP, Kleinstein, Steven H., PhD, Kipling, David, DPhil, Gould, Hannah J., PhD
Published in Journal of allergy and clinical immunology (01.09.2014)
Published in Journal of allergy and clinical immunology (01.09.2014)
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Journal Article
Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data
Gadala-Maria, Daniel, Gidoni, Moriah, Marquez, Susanna, Vander Heiden, Jason A, Kos, Justin T, Watson, Corey T, O'Connor, Kevin C, Yaari, Gur, Kleinstein, Steven H
Published in Frontiers in immunology (13.02.2019)
Published in Frontiers in immunology (13.02.2019)
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Journal Article
The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales
Yaari, Gur, Benichou, Jennifer I. C., Vander Heiden, Jason A., Kleinstein, Steven H., Louzoun, Yoram
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05.09.2015)
Published in Philosophical transactions of the Royal Society of London. Series B. Biological sciences (05.09.2015)
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Journal Article
Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data
Yaari, Gur, Vander Heiden, Jason A, Uduman, Mohamed, Gadala-Maria, Daniel, Gupta, Namita, Stern, Joel N H, O'Connor, Kevin C, Hafler, David A, Laserson, Uri, Vigneault, Francois, Kleinstein, Steven H
Published in Frontiers in immunology (2013)
Published in Frontiers in immunology (2013)
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Journal Article
Mutant Cellular AP-1 Proteins Promote Expression of a Subset of Epstein-Barr Virus Late Genes in the Absence of Lytic Viral DNA Replication
Lyons, Danielle E, Yu, Kuan-Ping, Vander Heiden, Jason A, Heston, Lee, Dittmer, Dirk P, El-Guindy, Ayman, Miller, George
Published in Journal of virology (01.10.2018)
Published in Journal of virology (01.10.2018)
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