Fractionation factors reveal hidden frustration in an ancient allosteric module
VanSchouwen, Bryan, Della Libera, Leonardo, Melacini, Giuseppe
Published in The Journal of chemical physics (28.03.2023)
Published in The Journal of chemical physics (28.03.2023)
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Role of Dynamics in the Autoinhibition and Activation of the Hyperpolarization-activated Cyclic Nucleotide-modulated (HCN) Ion Channels
VanSchouwen, Bryan, Akimoto, Madoka, Sayadi, Maryam, Fogolari, Federico, Melacini, Giuseppe
Published in The Journal of biological chemistry (17.07.2015)
Published in The Journal of biological chemistry (17.07.2015)
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A Mechanism for the Auto-inhibition of Hyperpolarization-activated Cyclic Nucleotide-gated (HCN) Channel Opening and Its Relief by cAMP
Akimoto, Madoka, Zhang, Zaiyong, Boulton, Stephen, Selvaratnam, Rajeevan, VanSchouwen, Bryan, Gloyd, Melanie, Accili, Eric A., Lange, Oliver F., Melacini, Giuseppe
Published in The Journal of biological chemistry (08.08.2014)
Published in The Journal of biological chemistry (08.08.2014)
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Distance-Based Configurational Entropy of Proteins from Molecular Dynamics Simulations
Fogolari, Federico, Corazza, Alessandra, Fortuna, Sara, Soler, Miguel Angel, VanSchouwen, Bryan, Brancolini, Giorgia, Corni, Stefano, Melacini, Giuseppe, Esposito, Gennaro
Published in PloS one (15.07.2015)
Published in PloS one (15.07.2015)
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An auto-inhibited state of protein kinase G and implications for selective activation
Sharma, Rajesh, Kim, Jeong Joo, Qin, Liying, Henning, Philipp, Akimoto, Madoka, VanSchouwen, Bryan, Kaur, Gundeep, Sankaran, Banumathi, MacKenzie, Kevin R, Melacini, Giuseppe, Casteel, Darren E, Herberg, Friedrich W, Kim, Choel
Published in eLife (05.08.2022)
Published in eLife (05.08.2022)
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Journal Article
Structural Basis for Cyclic-Nucleotide Selectivity and cGMP-Selective Activation of PKG I
Huang, Gilbert Y., Kim, Jeong Joo, Reger, Albert S., Lorenz, Robin, Moon, Eui-Whan, Zhao, Chi, Casteel, Darren E., Bertinetti, Daniela, VanSchouwen, Bryan, Selvaratnam, Rajeevan, Pflugrath, James W., Sankaran, Banumathi, Melacini, Giuseppe, Herberg, Friedrich W., Kim, Choel
Published in Structure (London) (07.01.2014)
Published in Structure (London) (07.01.2014)
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Procrustean rotation in concert with principal component analysis of molecular dynamics trajectories: Quantifying global and local differences between conformational samples
Oblinsky, Daniel G, Vanschouwen, Bryan M B, Gordon, Heather L, Rothstein, Stuart M
Published in The Journal of chemical physics (14.12.2009)
Published in The Journal of chemical physics (14.12.2009)
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Cracking the allosteric code of NMR chemical shifts
VanSchouwen, Bryan, Melacini, Giuseppe
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2016)
Published in Proceedings of the National Academy of Sciences - PNAS (23.08.2016)
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Journal Article
Mutual Protein-Ligand Conformational Selection Drives cGMP vs. cAMP Selectivity in Protein Kinase G
VanSchouwen, Bryan, Boulton, Stephen, Melacini, Giuseppe
Published in Journal of molecular biology (15.10.2021)
Published in Journal of molecular biology (15.10.2021)
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Journal Article
Water-mediated interactions in the CRP–cAMP–DNA complex: Does water mediate sequence-specific binding at the DNA primary-kink site?
VanSchouwen, Bryan M.B., Gordon, Heather L., Rothstein, Stuart M., Komeiji, Yuto, Fukuzawa, Kaori, Tanaka, Shigenori
Published in Computational biology and chemistry (01.06.2008)
Published in Computational biology and chemistry (01.06.2008)
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Molecular Mechanism for the (−)-Epigallocatechin Gallate-Induced Toxic to Nontoxic Remodeling of Aβ Oligomers
Ahmed, Rashik, VanSchouwen, Bryan, Jafari, Naeimeh, Ni, Xiaodan, Ortega, Joaquin, Melacini, Giuseppe
Published in Journal of the American Chemical Society (04.10.2017)
Published in Journal of the American Chemical Society (04.10.2017)
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Journal Article
Non-Canonical Allostery in Cyclic Nucleotide Dependent Kinases
Khamina, Mariia, Martinez Pomier, Karla, Akimoto, Madoka, VanSchouwen, Bryan, Melacini, Giuseppe
Published in Journal of molecular biology (15.09.2022)
Published in Journal of molecular biology (15.09.2022)
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