The influence of the time interval between monoHER and doxorubicin administration on the protection against doxorubicin-induced cardiotoxicity in mice
BRUYNZEEL, Anna M. E, MUL, Paula P. N, BERKHOF, Johannes, BAST, Aalt, NIESSEN, Hans W. M, VAN DER VIJGH, Wim J. F
Published in Cancer chemotherapy and pharmacology (01.11.2006)
Published in Cancer chemotherapy and pharmacology (01.11.2006)
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The flavonoid 7-mono-O-(β-hydroxyethyl)-rutoside is able to protect endothelial cells by a direct antioxidant effect
Lemmens, Kristien J.A., van de Wier, Bregje, Vaes, Nathalie, Ghosh, Mitrajit, van Zandvoort, Marc A.M.J., van der Vijgh, Wim J.F., Bast, Aalt, Haenen, Guido R.M.M.
Published in Toxicology in vitro (01.06.2014)
Published in Toxicology in vitro (01.06.2014)
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The chemical reactivity of BNP7787 and its metabolite mesna with the cytostatic agent cisplatin: comparison with the nucleophiles thiosulfate, DDTC, glutathione and its disulfide GSSG
VERSCHRAAGEN, Miranda, KEDDE, Marc A, HAUSHEER, Frederick H, VAN DER VIJGH, Wim J. F
Published in Cancer chemotherapy and pharmacology (01.06.2003)
Published in Cancer chemotherapy and pharmacology (01.06.2003)
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Identification of the Metabolites of the Antioxidant Flavonoid 7-Mono-O-(β-hydroxyethyl)-rutoside in Mice
JACOBS, Hilde, PETERS, Ron, DEN HARTOG, Gertjan J. M, VAN DER VIJGH, Wim J. F, BAST, Aalt, HAENEN, Guido R. M. M
Published in Drug metabolism and disposition (01.05.2011)
Published in Drug metabolism and disposition (01.05.2011)
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Bioavailability and pharmacokinetics of the cardioprotecting flavonoid 7-monohydroxyethylrutoside in mice
ABOU EL HASSAN, Mohamed A. I, KEDDE, Marc A, ZWIERS, Ursula T. H, TOURN, E, HAENEN, Guido R. M. M, BAST, Aalt, VAN DER VIJGH, Wim J. F
Published in Cancer chemotherapy and pharmacology (01.11.2003)
Published in Cancer chemotherapy and pharmacology (01.11.2003)
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Flavonoids as protectors against doxorubicin cardiotoxicity: Role of iron chelation, antioxidant activity and inhibition of carbonyl reductase
Kaiserová, Helena, Šimůnek, Tomáš, van der Vijgh, Wim J.F., Bast, Aalt, Kvasničková, Eva
Published in Biochimica et biophysica acta (01.09.2007)
Published in Biochimica et biophysica acta (01.09.2007)
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Simultaneous determination of BNP7787 and its metabolite mesna in plasma and tissue by micro-HPLC with a dual electrochemical detector
Verschraagen, Miranda, Zwiers, T.H.Ursula, Torun, Emine, Donker, Martin G., Reinhoud, Nico J., Van der Vijgh, Wim J.F.
Published in Journal of pharmaceutical sciences (01.05.2003)
Published in Journal of pharmaceutical sciences (01.05.2003)
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The contribution of the major metabolite 4′-O-methylmonoHER to the antioxidant activity of the flavonoid monoHER
Lemmens, Kristien J.A., Herst, Pauline M., Housmans, Bas A.C., Moalin, Mohamed, van der Vijgh, Wim J.F., Bast, Aalt, Haenen, Guido R.M.M.
Published in Chemico-biological interactions (05.09.2015)
Published in Chemico-biological interactions (05.09.2015)
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An essential difference in the reactivity of the glutathione adducts of the structurally closely related flavonoids monoHER and quercetin
Jacobs, Hilde, Moalin, Mohamed, van Gisbergen, Marike W., Bast, Aalt, van der Vijgh, Wim J.F., Haenen, Guido R.M.M.
Published in Free radical biology & medicine (01.12.2011)
Published in Free radical biology & medicine (01.12.2011)
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The minor structural difference between the antioxidants quercetin and 4'O-methylquercetin has a major impact on their selective thiol toxicity
Lemmens, Kristien J A, Vrolijk, Misha F, Bouwman, Freek G, van der Vijgh, Wim J F, Bast, Aalt, Haenen, Guido R M M
Published in International journal of molecular sciences (30.04.2014)
Published in International journal of molecular sciences (30.04.2014)
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The cardioprotector monoHER does not interfere with the pharmacokinetics or the metabolism of the cardiotoxic agent doxorubicin in mice
ABOU EL HASSAN, Mohamed A. I, KEDDE, Marc A, ZWIERS, Ursula T. H, BAST, Aalt, VAN DERVIJGH, Wim J. F
Published in Cancer chemotherapy and pharmacology (01.04.2003)
Published in Cancer chemotherapy and pharmacology (01.04.2003)
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Characterization of the glutathione conjugate of the semisynthetic flavonoid monoHER
Jacobs, Hilde, van der Vijgh, Wim J.F., Koek, Ger H., Draaisma, Guy J.J., Moalin, Mohamed, van Strijdonck, Gino P.F., Bast, Aalt, Haenen, Guido R.M.M.
Published in Free radical biology & medicine (15.06.2009)
Published in Free radical biology & medicine (15.06.2009)
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Alpha-tocopheryl phosphate is a novel apoptotic agent
Rezk, Bashir M, van der Vijgh, Wim J F, Bast, Aalt, Haenen, Guido R M M
Published in Frontiers in bioscience (01.01.2007)
Published in Frontiers in bioscience (01.01.2007)
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Vitamin D status and sex hormone binding globulin: determinants of bone turnover and bone mineral density in elderly women
Ooms, M E, Lips, P, Roos, J C, van der Vijgh, W J, Popp-Snijders, C, Bezemer, P D, Bouter, L M
Published in Journal of bone and mineral research (01.08.1995)
Published in Journal of bone and mineral research (01.08.1995)
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In vivo reduction of erythrocyte oxidant stress in a murine model of beta-thalassemia
de Franceschi, L, Turrini, F, Honczarenko, M, Ayi, K, Rivera, A, Fleming, MD, Law, T, Mannu, F, Kuypers, FA, Bast, A, van der Vijgh, WJ, Brugnara, C
Published in Haematologica (Roma) (01.11.2004)
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Published in Haematologica (Roma) (01.11.2004)
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