Efficient One-Pot Access to Trisubstituted 2-Benzazepin-3-ones as Constrained Pseudopeptide Analogues and Privileged Scaffolds
der Poorten, Olivier Van, Jida, Mouhamad, Tourwe, Dirk, Ballet, Steven
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.01.2018)
Published in Medicinal chemistry (Shp-sariqah, United Arab Emirates) (01.01.2018)
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Journal Article
Conformationally Constrained Peptidomimetics as Inhibitors of the Protein Arginine Methyl Transferases
Knuhtsen, Astrid, Legrand, Baptiste, Van der Poorten, Olivier, Amblard, Muriel, Martinez, Jean, Ballet, Steven, Kristensen, Jesper L., Pedersen, Daniel Sejer
Published in Chemistry : a European journal (19.09.2016)
Published in Chemistry : a European journal (19.09.2016)
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Journal Article
Indoloazepinone‐Constrained Oligomers as Cell‐Penetrating and Blood–Brain‐Barrier‐Permeating Compounds
Van der Poorten, Olivier, Legrand, Baptiste, Vezenkov, Lubomir L., García‐Pindado, Júlia, Bettache, Nadir, Knuhtsen, Astrid, Pedersen, Daniel Sejer, Sánchez‐Navarro, Macarena, Martinez, Jean, Teixidó, Meritxell, Garcia, Marcel, Tourwé, Dirk, Amblard, Muriel, Ballet, Steven
Published in Chembiochem : a European journal of chemical biology (04.04.2018)
Published in Chembiochem : a European journal of chemical biology (04.04.2018)
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Journal Article
Novel Cocrystal Structures of Peptide Antagonists Bound to the Human Melanocortin Receptor 4 Unveil Unexplored Grounds for Structure-Based Drug Design
Gimenez, Luis E., Martin, Charlotte, Yu, Jing, Hollanders, Charlie, Hernandez, Ciria C., Wu, Yiran, Yao, Deqiang, Han, Gye Won, Dahir, Naima S., Wu, Lijie, Van der Poorten, Olivier, Lamouroux, Arthur, Mannes, Morgane, Zhao, Suwen, Tourwé, Dirk, Stevens, Raymond C., Cone, Roger D., Ballet, Steven
Published in Journal of medicinal chemistry (22.02.2024)
Published in Journal of medicinal chemistry (22.02.2024)
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Journal Article
3-Substituted 2-isocyanopyridines as versatile convertible isocyanides for peptidomimetic design
Hollanders, Charlie, Elsocht, Mathias, Van der Poorten, Olivier, Jida, Mouhamad, Renders, Evelien, Maes, Bert U. W, Ballet, Steven
Published in Chemical communications (Cambridge, England) (13.07.2021)
Published in Chemical communications (Cambridge, England) (13.07.2021)
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Journal Article
Structure-Based Design of Melanocortin 4 Receptor Ligands Based on the SHU-9119-hMC4R Cocrystal Structure
Martin, Charlotte, Gimenez, Luis E., Williams, Savannah Y., Jing, Yu, Wu, Yiran, Hollanders, Charlie, Van der Poorten, Olivier, Gonzalez, Simon, Van Holsbeeck, Kevin, Previti, Santo, Lamouroux, Arthur, Zhao, Suwen, Tourwe, Dirk, Stevens, Raymond C., Cone, Roger D., Ballet, Steven
Published in Journal of medicinal chemistry (14.01.2021)
Published in Journal of medicinal chemistry (14.01.2021)
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Using conformational constraints at position 6 of Angiotensin II to generate compounds with enhanced AT2R selectivity and proteolytic stability
Tourwé, Dirk, Tsiailanis, Antonis D., Parisis, Nikolaos, Hirmiz, Baydaa, Del Borgo, Mark, Aguilar, Marie-Isabel, Van der Poorten, Olivier, Ballet, Steven, Widdop, Robert E., Tzakos, Andreas G.
Published in Bioorganic & medicinal chemistry letters (01.07.2021)
Published in Bioorganic & medicinal chemistry letters (01.07.2021)
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Journal Article
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists
Claff, Tobias, Yu, Jing, Blais, Véronique, Patel, Nilkanth, Martin, Charlotte, Wu, Lijie, Han, Gye Won, Holleran, Brian J, Van der Poorten, Olivier, White, Kate L, Hanson, Michael A, Sarret, Philippe, Gendron, Louis, Cherezov, Vadim, Katritch, Vsevolod, Ballet, Steven, Liu, Zhi-Jie, Müller, Christa E, Stevens, Raymond C
Published in Science advances (01.11.2019)
Published in Science advances (01.11.2019)
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Journal Article
T3P-Promoted, Mild, One-Pot Syntheses of Constrained Polycyclic Lactam Dipeptide Analogues via Stereoselective Pictet–Spengler and Meyers Lactamization Reactions
Jida, Mouhamad, Van der Poorten, Olivier, Guillemyn, Karel, Urbanczyk-Lipkowska, Zofia, Tourwé, Dirk, Ballet, Steven
Published in Organic letters (18.09.2015)
Published in Organic letters (18.09.2015)
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Journal Article
Synthesis and biological evaluation of compact, conformationally constrained bifunctional opioid agonist – Neurokinin-1 antagonist peptidomimetics
Guillemyn, Karel, Kleczkowska, Patrycia, Lesniak, Anna, Dyniewicz, Jolanta, Van der Poorten, Olivier, Van den Eynde, Isabelle, Keresztes, Attila, Varga, Eva, Lai, Josephine, Porreca, Frank, Chung, Nga N., Lemieux, Carole, Mika, Joanna, Rojewska, Ewelina, Makuch, Wioletta, Van Duppen, Joost, Przewlocka, Barbara, Vanden Broeck, Jozef, Lipkowski, Andrzej W., Schiller, Peter W., Tourwé, Dirk, Ballet, Steven
Published in European journal of medicinal chemistry (06.03.2015)
Published in European journal of medicinal chemistry (06.03.2015)
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Journal Article
Indoloazepinone-Containing Oligomers as Cell-Penetrating (Non)Peptides: Synthesis, Structuration and Internalization
van Der Poorten, Olivier, Legrand, Baptiste, Vezenkov, Lubomir, Martinez, Jean, Bettache, Nadir, Garcia, Marcel, Tourwé, Dirk, Amblard, Muriel, Ballet, Steven
Published in Journal of peptide science (04.04.2018)
Published in Journal of peptide science (04.04.2018)
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Journal Article
Synthesis of 3-amino-3,4-dihydro-1H-quinolin-2-ones through regioselective palladium-catalyzed intramolecular cyclization
Hallé, François, Van der Poorten, Olivier, Doebelin, Christelle, Niederst, Marie, Schneider, Séverine, Schmitt, Martine, Ballet, Steven, Bihel, Frédéric
Published in Tetrahedron letters (06.04.2016)
Published in Tetrahedron letters (06.04.2016)
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Journal Article
Azepinone-Containing Tetrapeptide Analogues of Melanotropin Lead to Selective h MC4R Agonists and h MC5R Antagonist
Van der Poorten, Olivier, Fehér, Krisztina, Buysse, Koen, Feytens, Debby, Zoi, Ioanna, Schwartz, Steven D., Martins, José C., Tourwé, Dirk, Cai, Minying, Hruby, Victor J., Ballet, Steven
Published in ACS medicinal chemistry letters (12.02.2015)
Published in ACS medicinal chemistry letters (12.02.2015)
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Journal Article
χ‑Space Screening of Dermorphin-Based Tetrapeptides through Use of Constrained Arylazepinone and Quinolinone Scaffolds
Van der Poorten, Olivier, Van Den Hauwe, Robin, Eiselt, Emilie, Betti, Cecilia, Guillemyn, Karel, Chung, Nga N, Hallé, François, Bihel, Frédéric, Schiller, Peter W, Tourwé, Dirk, Sarret, Philippe, Gendron, Louis, Ballet, Steven
Published in ACS medicinal chemistry letters (09.11.2017)
Published in ACS medicinal chemistry letters (09.11.2017)
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Journal Article
Azepinone-Containing Tetrapeptide Analogues of Melanotropin Lead to Selective hMC4R Agonists and hMC5R Antagonist
Van der Poorten, Olivier, Fehér, Krisztina, Buysse, Koen, Feytens, Debby, Zoi, Ioanna, Schwartz, Steven D, Martins, José C, Tourwé, Dirk, Cai, Minying, Hruby, Victor J, Ballet, Steven
Published in ACS medicinal chemistry letters (12.02.2015)
Published in ACS medicinal chemistry letters (12.02.2015)
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Journal Article
ChemInform Abstract: Synthesis of 3‐Amino‐3,4‐dihydro‐1H‐quinolin‐2‐ones Through Regioselective Palladium‐Catalyzed Intramolecular Cyclization
Halle, Francois, Van der Poorten, Olivier, Doebelin, Christelle, Niederst, Marie, Schneider, Severine, Schmitt, Martine, Ballet, Steven, Bihel, Frederic
Published in ChemInform (01.07.2016)
Published in ChemInform (01.07.2016)
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Journal Article
ChemInform Abstract: T3P‐Promoted, Mild, One‐Pot Syntheses of Constrained Polycyclic Lactam Dipeptide Analogues via Stereoselective Pictet—Spengler and Meyers Lactamization Reactions
Jida, Mouhamad, Van der Poorten, Olivier, Guillemyn, Karel, Urbanczyk‐Lipkowska, Zofia, Tourwe, Dirk, Ballet, Steven
Published in ChemInform (01.01.2016)
Published in ChemInform (01.01.2016)
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