Orexigenic Action of Peripheral Ghrelin Is Mediated by Neuropeptide Y and Agouti-Related Protein
Chen, H. Y, Trumbauer, M. E, Chen, A. S, Weingarth, D. T, Adams, J. R, Frazier, E. G, Shen, Z, Marsh, D. J, Feighner, S. D, Guan, X.-M, Ye, Z, Nargund, R. P, Smith, R. G, Van der Ploeg, L. H. T, Howard, A. D, MacNeil, D. J, Qian, S
Published in Endocrinology (Philadelphia) (01.06.2004)
Published in Endocrinology (Philadelphia) (01.06.2004)
Get full text
Journal Article
Structure−Activity Studies of the Melanocortin Peptides: Discovery of Potent and Selective Affinity Antagonists for the hMC3 and hMC4 Receptors
Grieco, Paolo, Lavecchia, Antonio, Cai, Minying, Trivedi, Devendra, Weinberg, David, MacNeil, Tanya, Van der Ploeg, L. H. T, Hruby, Victor J
Published in Journal of medicinal chemistry (21.11.2002)
Published in Journal of medicinal chemistry (21.11.2002)
Get full text
Journal Article
Characterization of a novel and selective cannabinoid CB1 receptor inverse agonist, Imidazole 24b, in rodents
SHEARMAN, Lauren P, SLOAN STRIBLING, D, SPANN, Stephanie K, MACNEIL, Douglas J, FONG, Tung M, METZGER, Joseph M, GOULET, Mark T, HAGMANN, William K, PLUMMER, Christopher W, FINKE, Paul E, MILLS, Sander G, SHAH, Shrenik K, CAMACHO, Ramon E, TRUONG, Quang, VAN DER PLOEG, L. H. T, EUAN MACINTYRE, D, STRACK, Alison M, ROSKO, Kimberly M, JUNYING WANG, TONG, Sharon, YUE FENG, MARSH, Donald J, HONG YU, XIAOMING GUAN
Published in European journal of pharmacology (28.01.2008)
Published in European journal of pharmacology (28.01.2008)
Get full text
Journal Article
Molecular Interaction of Agouti Protein and Agouti-Related Protein with Human Melanocortin Receptors
Tota, M. R, Smith, T. S, Mao, C, MacNeil, T, Mosley, R. T, Van der Ploeg, L. H. T, Fong, T. M
Published in Biochemistry (Easton) (19.01.1999)
Published in Biochemistry (Easton) (19.01.1999)
Get full text
Journal Article
Induction of c-fos mRNA in the arcuate nucleus of normal and mutant growth hormone-deficient mice by a synthetic non-peptidyl growth hormone secretagogue
Sirinathsinghji, D J, Chen, H Y, Hopkins, R, Trumbauer, M, Heavens, R, Rigby, M, Smith, R G, van der Ploeg, L H
Published in Neuroreport (1995)
Published in Neuroreport (1995)
Get more information
Journal Article
Ghrelin
Müller, T.D, Nogueiras, R, Andermann, M.L, Andrews, Z.B, Anker, S.D, Argente, J, Batterham, R.L, Benoit, S.C, Bowers, C.Y, Broglio, F, Casanueva, F.F, D'Alessio, D, Depoortere, I, Geliebter, A, Ghigo, E, Cole, P.A, Cowley, M, Cummings, D.E, Dagher, A, Diano, S, Dickson, S.L, Diéguez, C, Granata, R, Grill, H.J, Grove, K, Habegger, K.M, Heppner, K, Heiman, M.L, Holsen, L, Holst, B, Inui, A, Jansson, J.O, Kirchner, H, Korbonits, M, Laferrère, B, LeRoux, C.W, Lopez, M, Morin, S, Nakazato, M, Nass, R, Perez-Tilve, D, Pfluger, P.T, Schwartz, T.W, Seeley, R.J, Sleeman, M, Sun, Y, Sussel, L, Tong, J, Thorner, M.O, van der Lely, A.J, van der Ploeg, L.H.T, Zigman, J.M, Kojima, M, Kangawa, K, Smith, R.G, Horvath, T, Tschöp, M.H
Published in Molecular metabolism (Germany) (01.06.2015)
Published in Molecular metabolism (Germany) (01.06.2015)
Get full text
Journal Article
Mice deficient for the amyloid precursor protein gene
Zheng, H, Jiang, M, Trumbauer, M E, Hopkins, R, Sirinathsinghji, D J, Stevens, K A, Conner, M W, Slunt, H H, Sisodia, S S, Chen, H Y, Van der Ploeg, L H
Published in Annals of the New York Academy of Sciences (01.01.1996)
Published in Annals of the New York Academy of Sciences (01.01.1996)
Get more information
Journal Article
Extensive structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5
Grieco, P., Balse-Srinivasan, P., Han, G., Weinberg, D., MacNeil, T., Van der Ploeg, L. H. T., Hruby, V. J.
Published in The journal of peptide research (01.11.2003)
Published in The journal of peptide research (01.11.2003)
Get full text
Journal Article
Synthesis and biological evaluation on hMC3, hMC4 and hMC5 receptors of γ-MSH analogs substituted with l-alanine
Grieco, P., Balse-Srinivasan, P., Han, G., Hruby, V.J., Weinberg, D., MacNeil, T., Van der Ploeg, L. H. T.
Published in The journal of peptide research (01.05.2002)
Published in The journal of peptide research (01.05.2002)
Get full text
Journal Article
Ordered Appearance of Antigenic Variants of African Trypanosomes Explained in a Mathematical Model Based on a Stochastic Switch Process and Immune-Selection against Putative Switch Intermediates
Agur, Z., Abiri, D., Van Der Ploeg, L. H. T.
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.1989)
Published in Proceedings of the National Academy of Sciences - PNAS (01.12.1989)
Get full text
Journal Article
Down‐regulation of the Notch pathway mediated by a γ‐secretase inhibitor induces anti‐tumour effects in mouse models of T‐cell leukaemia
Tammam, J, Ware, C, Efferson, C, O'Neil, J, Rao, S, Qu, X, Gorenstein, J, Angagaw, M, Kim, H, Kenific, C, Kunii, K, Leach, KJ, Nikov, G, Zhao, J, Dai, X, Hardwick, J, Scott, M, Winter, C, Bristow, L, Elbi, C, Reilly, JF, Look, T, Draetta, G, Van der Ploeg, LHT, Kohl, NE, Strack, PR, Majumder, PK
Published in British journal of pharmacology (01.11.2009)
Published in British journal of pharmacology (01.11.2009)
Get full text
Journal Article
Identification of receptors for neuromedin U and its role in feeding
Liu, Qingyun, Howard, Andrew D, Wang, Ruiping, Pong, Sheng-Shung, Mellin, Theodore N, Strack, Alison, Guan, Xiao-Ming, Zeng, Zhizhen, Williams, David L, Feighner, Scott D, Nunes, Christian N, Murphy, Beth, Stair, Judith N, Yu, Hong, Jiang, Qingping, Clements, Michelle K, Tan, Carina P, McKee, Karen K, Hreniuk, Donna L, McDonald, Terrence P, Lynch, Kevin R, Evans, Jilly F, Austin, Christopher P, Caskey, C. Thomas, Van der Ploeg, Lex H. T
Published in Nature (London) (06.07.2000)
Published in Nature (London) (06.07.2000)
Get full text
Journal Article
A Receptor in Pituitary and Hypothalamus that Functions in Growth Hormone Release
Howard, Andrew D., Feighner, Scott D., Cully, Doris F., Arena, Joseph P., Liberator, Paul A., Rosenblum, Charles I., Hamelin, Michel, Hreniuk, Donna L., Palyha, Oksana C., Anderson, Jennifer, Paress, Philip S., Diaz, Carmen, Chou, Michael, Liu, Ken K., McKee, Karen Kulju, Pong, Sheng-Shung, Chaung, Lee-Yuh, Elbrecht, Alex, Dashkevicz, Mike, Heavens, Robert, Rigby, Mike, Dalip J. S. Sirinathsinghji, Dean, Dennis C., Melillo, David G., Patchett, Arthur A., Nargund, Ravi, Griffin, Patrick R., DeMartino, Julie A., Gupta, Sunil K., Schaeffer, James M., Smith, Roy G., Lex H. T. van der Ploeg
Published in Science (American Association for the Advancement of Science) (16.08.1996)
Published in Science (American Association for the Advancement of Science) (16.08.1996)
Get full text
Journal Article
Peptidomimetic Regulation of Growth Hormone Secretion
Smith, Roy G, Van der Ploeg, Lex H. T, Howard, Andrew D, Feighner, Scott D, Cheng, Kang, Hickey, Gerard J, Wyvratt, Matthew J, Fisher, Mike H, Nargund, Ravi P, Patchett, Arthur A
Published in Endocrine reviews (01.10.1997)
Published in Endocrine reviews (01.10.1997)
Get full text
Journal Article
Receptor for Motilin Identified in the Human Gastrointestinal System
Feighner, Scott D., Tan, Carina P., McKee, Karen Kulju, Palyha, Oksana C., Hreniuk, Donna L., Pong, Sheng-Shung, Austin, Christopher P., Figueroa, David, MacNeil, Douglas, Cascieri, Margaret A., Nargund, Ravi, Bakshi, Raman, Abramovitz, Mark, Stocco, Rino, Kargman, Stacia, O'Neill, Gary, Lex H. T. Van Der Ploeg, Evans, Jilly, Patchett, Arthur A., Smith, Roy G., Howard, Andrew D.
Published in Science (American Association for the Advancement of Science) (25.06.1999)
Published in Science (American Association for the Advancement of Science) (25.06.1999)
Get full text
Journal Article
Age-related cognitive deficits, impaired long-term potentiation and reduction in synaptic marker density in mice lacking the β-amyloid precursor protein
Dawson, G.R, Seabrook, G.R, Zheng, H, Smith, D.W, Graham, S, O'Dowd, G, Bowery, B.J, Boyce, S, Trumbauer, M.E, Chen, H.Y, Van der Ploeg, L.H.T, Sirinathsinghji, D.J.S
Published in Neuroscience (01.01.1999)
Published in Neuroscience (01.01.1999)
Get full text
Journal Article
Generation of APLP2 KO Mice and Early Postnatal Lethality in APLP2/APP Double KO Mice
von Koch, C.S., Zheng, H., Chen, H., Trumbauer, M., Thinakaran, G., van der Ploeg, L.H.T., Price, D.L., Sisodia, S.S.
Published in Neurobiology of aging (01.11.1997)
Published in Neurobiology of aging (01.11.1997)
Get full text
Journal Article
Conference Proceeding