Optimization of N'-(arylsulfonyl)pyrazoline-1-carboxamidines by exploiting a novel interaction site in the 5-HT sub(6) antagonistic binding pocket
Loevezijn, Arnold van, Venhorst, Jennifer, Bakker, Wouter IIwema, Lange, Jos HM, Looff, Wouter de, Henzen, Remco, Vries, Jelle de, Woestijne, Rob Pvan de, Hartog, Arnold Pden, Verhoog, Stefan, van der Neut, Martina AW, Bruin, Natasja MWJde, Kruse, Chris G
Published in Bioorganic & medicinal chemistry letters (15.03.2016)
Published in Bioorganic & medicinal chemistry letters (15.03.2016)
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Probing the cannabinoid CB sub(1)/CB sub(2) receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern
Lange, Jos HM, Van der Neut, Martina AW, Borst, Alice JM, Yildirim, Mahmut, Van Stuivenberg, Herman H, Van Vliet, Bernard J, Kruse, Chris G
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
Published in Bioorganic & medicinal chemistry letters (01.05.2010)
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Synthesis, SAR and intramolecular hydrogen bonding pattern of 1,3,5-trisubstituted 4,5-dihydropyrazoles as potent cannabinoid CB sub(1) receptor antagonists
Lange, Jos HM, Van der Neut, Martina AW, Hartog, Arnold Pden, Wals, Henri C, Hoogendoorn, Jan, Van Stuivenberg, Herman H, Van Vliet, Bernard J, Kruse, Chris G
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
Published in Bioorganic & medicinal chemistry letters (01.03.2010)
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Synthesis and SAR of novel imidazoles as potent and selective cannabinoid CB sub(2) receptor antagonists with high binding efficiencies
Lange, Jos HM, Van der Neut, Martina AW, Wals, Henri C, Kuil, Gijs D, Borst, Alice JM, Mulder, Arie, Hartog, Arnold Pden, Zilaout, Hicham, Goutier, Wouter, Van Stuivenberg, Herman H, Van Vliet, Bernard J
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
Published in Bioorganic & medicinal chemistry letters (01.02.2010)
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ΠΑΡΑΓΩΓΑ ΣΟΥΛΦΟΝΥΛΟΠΥΡΑΖΟΛΙΝΟ-1-ΚΑΡΒΟΞΑΜΙΔΙΝΗΣ ΩΣ 5-ΗΤ6 ΑΝΤΑΓΩΝΙΣΤΕΣ
NEUT VAN DER MARTINA AW, KRUSE CORNELIS G, IWEMA BAKKER WOUTER I, KEIZER HISKIAS G, LOEVEZIJN VAN ARNOLD, ZORGDRAGER JAN
Year of Publication 09.12.2015
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Year of Publication 09.12.2015
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