Integration of the PD-L1 inhibitor atezolizumab and WT1/DC vaccination into standard-of-care first-line treatment for patients with epithelioid malignant pleural mesothelioma-Protocol of the Immuno-MESODEC study
Van den Bossche, Jolien, De Laere, Maxime, Deschepper, Koen, Germonpré, Paul, Valcke, Yvan, Lamont, Jan, Stein, Barbara, Van Camp, Kirsten, Germonpré, Charlotte, Nijs, Griet, Roelant, Ella, Anguille, Sébastien, Lion, Eva, Berneman, Zwi
Published in PloS one (15.07.2024)
Published in PloS one (15.07.2024)
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Journal Article
The MDM2-inhibitor Nutlin-3 synergizes with cisplatin to induce p53 dependent tumor cell apoptosis in non-small cell lung cancer
Deben, Christophe, Wouters, An, Op de Beeck, Ken, van Den Bossche, Jolien, Jacobs, Julie, Zwaenepoel, Karen, Peeters, Marc, Van Meerbeeck, Jan, Lardon, Filip, Rolfo, Christian, Deschoolmeester, Vanessa, Pauwels, Patrick
Published in Oncotarget (08.09.2015)
Published in Oncotarget (08.09.2015)
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Journal Article
Simultaneous targeting of EGFR, HER2, and HER4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines
De Pauw, Ines, Lardon, Filip, Van den Bossche, Jolien, Baysal, Hasan, Fransen, Erik, Deschoolmeester, Vanessa, Pauwels, Patrick, Peeters, Marc, Vermorken, Jan Baptist, Wouters, An
Published in Molecular oncology (01.06.2018)
Published in Molecular oncology (01.06.2018)
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Journal Article
Unveiling a CD70-positive subset of cancer-associated fibroblasts marked by pro-migratory activity and thriving regulatory T cell accumulation
Jacobs, Julie, Deschoolmeester, Vanessa, Zwaenepoel, Karen, Flieswasser, Tal, Deben, Christophe, Van den Bossche, Jolien, Hermans, Christophe, Rolfo, Christian, Peeters, Marc, De Wever, Olivier, Lardon, Filip, Siozopoulou, Vasiliki, Smits, Evelien, Pauwels, Patrick
Published in Oncoimmunology (03.07.2018)
Published in Oncoimmunology (03.07.2018)
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Journal Article
Overcoming Intrinsic and Acquired Cetuximab Resistance in RAS Wild-Type Colorectal Cancer: An In Vitro Study on the Expression of HER Receptors and the Potential of Afatinib
De Pauw, Ines, Lardon, Filip, Van den Bossche, Jolien, Baysal, Hasan, Pauwels, Patrick, Peeters, Marc, Vermorken, Jan Baptist, Wouters, An
Published in Cancers (15.01.2019)
Published in Cancers (15.01.2019)
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Journal Article
Adjuvant Wilms’ tumour 1-specific dendritic cell immunotherapy complementing conventional therapy for paediatric patients with high-grade glioma and diffuse intrinsic pontine glioma: protocol of a monocentric phase I/II clinical trial in Belgium
Van Genechten, Toon, De Laere, Maxime, Van den Bossche, Jolien, Stein, Barbara, De Rycke, kim, Deschepper, Caroline, Hazes, Katja, Peeters, Renke, Couttenye, Marie-Madeleine, Van De Walle, Katrien, Roelant, Ella, Maes, Sabine, Vanden Bossche, Stephanie, Dekeyzer, Sven, Huizing, Manon, Caluwaert, Kim, Nijs, Griet, Cools, Nathalie, Verlooy, Joris, Norga, Koen, Verhulst, Stijn, Anguille, Sebastien, Berneman, Zwi, Lion, Eva
Published in BMJ open (18.03.2024)
Published in BMJ open (18.03.2024)
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Journal Article
In vitro study of the Polo‐like kinase 1 inhibitor volasertib in non‐small‐cell lung cancer reveals a role for the tumor suppressor p53
Bossche, Jolien, Deben, Christophe, De Pauw, Ines, Lambrechts, Hilde, Hermans, Christophe, Deschoolmeester, Vanessa, Jacobs, Julie, Specenier, Pol, Pauwels, Patrick, Vermorken, Jan Baptist, Peeters, Marc, Lardon, Filip, Wouters, An
Published in Molecular oncology (01.05.2019)
Published in Molecular oncology (01.05.2019)
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Journal Article
Unlocking the potential of CD70 as a novel immunotherapeutic target for non-small cell lung cancer
Jacobs, Julie, Zwaenepoel, Karen, Rolfo, Christian, Van den Bossche, Jolien, Deben, Christophe, Silence, Karen, Hermans, Christophe, Smits, Evelien, Van Schil, Paul, Lardon, Filip, Deschoolmeester, Vanessa, Pauwels, Patrick
Published in Oncotarget (30.05.2015)
Published in Oncotarget (30.05.2015)
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Journal Article
Radiosensitization of Non-Small Cell Lung Cancer Cells by the Plk1 Inhibitor Volasertib Is Dependent on the p53 Status
Van den Bossche, Jolien, Domen, Andreas, Peeters, Marc, Deben, Christophe, De Pauw, Ines, Jacobs, Julie, De Bruycker, Sven, Specenier, Pol, Pauwels, Patrick, Vermorken, Jan Baptist, Lardon, Filip, Wouters, An
Published in Cancers (28.11.2019)
Published in Cancers (28.11.2019)
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Journal Article
Dual Targeting of Epidermal Growth Factor Receptor and HER3 by MEHD7945A as Monotherapy or in Combination with Cisplatin Partially Overcomes Cetuximab Resistance in Head and Neck Squamous Cell Carcinoma Cell Lines
De Pauw, Ines, Wouters, An, Van den Bossche, Jolien, Deschoolmeester, Vanessa, Baysal, Hasan, Pauwels, Patrick, Peeters, Marc, Vermorken, Jan B, Lardon, Filip
Published in Cancer biotherapy & radiopharmaceuticals (01.09.2017)
Published in Cancer biotherapy & radiopharmaceuticals (01.09.2017)
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Journal Article
Simultaneous targeting of EGFR , HER 2, and HER 4 by afatinib overcomes intrinsic and acquired cetuximab resistance in head and neck squamous cell carcinoma cell lines
De Pauw, Ines, Lardon, Filip, Van den Bossche, Jolien, Baysal, Hasan, Fransen, Erik, Deschoolmeester, Vanessa, Pauwels, Patrick, Peeters, Marc, Vermorken, Jan Baptist, Wouters, An
Published in Molecular oncology (01.06.2018)
Published in Molecular oncology (01.06.2018)
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Journal Article
Preclinical data on the combination of cisplatin and anti-CD70 therapy in non-small cell lung cancer as an excellent match in the era of combination therapy
Jacobs, Julie, Deschoolmeester, Vanessa, Rolfo, Christian, Zwaenepoel, Karen, Van den Bossche, Jolien, Deben, Christophe, Silence, Karen, de Haard, Hans, Hermans, Christophe, Rottey, Sylvie, Vangestel, Christel, Lardon, Filip, Smits, Evelien, Pauwels, Patrick
Published in Oncotarget (26.09.2017)
Published in Oncotarget (26.09.2017)
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Journal Article
The hypoxic tumor microenvironment and drug resistance against EGFR inhibitors: preclinical study in cetuximab-sensitive head and neck squamous cell carcinoma cell lines
Boeckx, Carolien, Van den Bossche, Jolien, De Pauw, Ines, Peeters, Marc, Lardon, Filip, Baay, Marc, Wouters, An
Published in BMC research notes (02.06.2015)
Published in BMC research notes (02.06.2015)
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Journal Article
APR-246 (PRIMA-1MET ) strongly synergizes with AZD2281 (olaparib) induced PARP inhibition to induce apoptosis in non-small cell lung cancer cell lines
Deben, Christophe, Lardon, Filip, Wouters, An, Op de Beeck, Ken, van Den Bossche, Jolien, Jacobs, Julie, Van Der Steen, Nele, Peeters, Marc, Rolfo, Christian, Deschoolmeester, Vanessa, Pauwels, Patrick
Published in Cancer letters (01.06.2016)
Published in Cancer letters (01.06.2016)
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Journal Article
Hypoxia-Induced Cisplatin Resistance in Non-Small Cell Lung Cancer Cells Is Mediated by HIF-1α and Mutant p53 and Can Be Overcome by Induction of Oxidative Stress
Deben, Christophe, Deschoolmeester, Vanessa, De Waele, Jorrit, Jacobs, Julie, Van den Bossche, Jolien, Wouters, An, Peeters, Marc, Rolfo, Christian, Smits, Evelien, Lardon, Filip, Pauwels, Patrick
Published in Cancers (21.04.2018)
Published in Cancers (21.04.2018)
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Journal Article
Abstract 4102: Overcoming intrinsic and acquired cetuximab resistance: an in vitro study on the potential of afatinib in HNSCC cell lines
Pauw, Ines De, Wouters, An, Bossche, Jolien Van den, Deschoolmeester, Vanessa, Pauwels, Patrick, Vermorken, Jan B., Peeters, Marc, Lardon, Filip
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Abstract 1056: Volasertib in combination with radiotherapy: The perfect match in non-small cell lung cancer
Bossche, Jolien Van den, Pauw, Ines De, Lambrechts, Hilde, Merlin, Céline, Deben, Christophe, Deschoolmeester, Vanessa, Specenier, Pol, Pauwels, Patrick, Peeters, Marc, Lardon, Filip, Wouters, An
Published in Cancer research (Chicago, Ill.) (01.07.2017)
Published in Cancer research (Chicago, Ill.) (01.07.2017)
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Journal Article
Deep sequencing of the TP53 gene reveals a potential risk allele for non–small cell lung cancer and supports the negative prognostic value of TP53 variants
Deben, Christophe, Van den Bossche, Jolien, Van Der Steen, Nele, Lardon, Filip, Wouters, An, de Beeck, Ken Op, Hermans, Christophe, Jacobs, Julie, Peeters, Marc, Van Camp, Guy, Rolfo, Christian, Deschoolmeester, Vanessa, Pauwels, Patrick
Published in Tumor biology (01.02.2017)
Published in Tumor biology (01.02.2017)
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Journal Article
Abstract 3507: APR-246 reactivates mutant p53 in non-small cell lung cancer cell lines and sensitizes cells for CDDP treatment under normoxic and hypoxic conditions
Deben, Christophe, Deschoolmeester, Vanessa, Wouters, An, Van den Bossche, Jolien, Jacobs, Julie, Lardon, Filip, Rolfo, Christian, Pauwels, Patrick
Published in Cancer research (Chicago, Ill.) (01.08.2015)
Published in Cancer research (Chicago, Ill.) (01.08.2015)
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Journal Article
Abstract 258: Is P53 the up-and-coming predictive biomarker for volasertib treatment in NSCLC
Van den Bossche, Jolien, Lardon, Filip, Deben, Christophe, De Pauw, Ines, Deschoolmeester, Vanessa, Smits, Evelien, Specenier, Pol, Pauwels, Patrick, Peeters, Marc, Wouters, An
Published in Cancer research (Chicago, Ill.) (15.07.2016)
Published in Cancer research (Chicago, Ill.) (15.07.2016)
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Journal Article