Adaptive immune response to whole cell pertussis vaccine reflects vaccine quality: A possible complementation to the Pertussis Serological Potency test
Hoonakker, M.E, Verhagen, L.M, van der Maas, L, Metz, B, Uittenbogaard, J.P, van de Waterbeemd, B, van Els, C.A.C.M, van Eden, W, Hendriksen, C.F.M, Sloots, A, Han, W.G.H
Published in Vaccine (17.08.2016)
Published in Vaccine (17.08.2016)
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Journal Article
practical approach for exploration and modeling of the design space of a bacterial vaccine cultivation process
Streefland, M, Van Herpen, P.F.G, Van de Waterbeemd, B, Van der Pol, L.A, Beuvery, E.C, Tramper, J, Martens, D.E, Toft, M
Published in Biotechnology and bioengineering (15.10.2009)
Published in Biotechnology and bioengineering (15.10.2009)
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Journal Article
Improved OMV vaccine against Neisseria meningitidis using genetically engineered strains and a detergent-free purification process
van de Waterbeemd, Bas, Streefland, Mathieu, van der Ley, Peter, Zomer, Bert, van Dijken, Harry, Martens, Dirk, Wijffels, René, van der Pol, Leo
Published in Vaccine (05.07.2010)
Published in Vaccine (05.07.2010)
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Journal Article
Improved production process for native outer membrane vesicle vaccine against Neisseria meningitidis
van de Waterbeemd, Bas, Zomer, Gijsbert, Kaaijk, Patricia, Ruiterkamp, Nicole, Wijffels, René H, van den Dobbelsteen, Germie P J M, van der Pol, Leo A
Published in PloS one (31.05.2013)
Published in PloS one (31.05.2013)
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Quantitative Proteomics Reveals Distinct Differences in the Protein Content of Outer Membrane Vesicle Vaccines
van de Waterbeemd, Bas, Mommen, Geert P. M, Pennings, Jeroen L. A, Eppink, Michel H, Wijffels, René H, van der Pol, Leo A, de Jong, Ad P. J. M
Published in Journal of proteome research (05.04.2013)
Published in Journal of proteome research (05.04.2013)
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Journal Article
Identification and optimization of critical process parameters for the production of NOMV vaccine against Neisseria meningitidis
van de Waterbeemd, Bas, Streefland, Mathieu, van Keulen, Lonneke, van den IJssel, Jan, de Haan, Alex, Eppink, Michel H, van der Pol, Leo A
Published in Vaccine (21.05.2012)
Published in Vaccine (21.05.2012)
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Unbiased Selective Isolation of Protein N-Terminal Peptides from Complex Proteome Samples Using Phospho Tagging PTAG) and TiO2-based Depletion
Mommen, G.P.M, Waterbeemd, B., van de, Meiring, H.D, Kersten, G, Heck, A.J.R, Jong, A.P.J.M., de
Published in Molecular & cellular proteomics (2012)
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Published in Molecular & cellular proteomics (2012)
Journal Article
Cysteine depletion causes oxidative stress and triggers outer membrane vesicle release by Neisseria meningitidis; implications for vaccine development
van de Waterbeemd, Bas, Zomer, Gijsbert, van den Ijssel, Jan, van Keulen, Lonneke, Eppink, Michel H, van der Ley, Peter, van der Pol, Leo A
Published in PloS one (23.01.2013)
Published in PloS one (23.01.2013)
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Gene-expression-based quality scores indicate optimal harvest point in Bordetella pertussis cultivation for vaccine production
van de Waterbeemd, Bas, Streefland, Mathieu, Pennings, Jeroen, van der Pol, Leo, Beuvery, Coen, Tramper, Johannes, Martens, Dirk
Published in Biotechnology and bioengineering (01.08.2009)
Published in Biotechnology and bioengineering (01.08.2009)
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Journal Article
PAT for vaccines: The first stage of PAT implementation for development of a well-defined whole-cell vaccine against whooping cough disease
Streefland, Mathieu, van de Waterbeemd, Bas, Happé, Hester, van der Pol, Leo A, Beuvery, E. Coen, Tramper, Johannes, Martens, Dirk E
Published in Vaccine (20.04.2007)
Published in Vaccine (20.04.2007)
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Conference Proceeding
Expression of phosphofructokinase in Neisseria meningitidis
Baart, Gino J. E, Langenhof, Marc, van de Waterbeemd, Bas, Hamstra, Hendrik-Jan, Zomer, Bert, van der Pol, Leo A, Beuvery, E. C, Tramper, Johannes, Martens, Dirk E
Published in Microbiology (Society for General Microbiology) (01.02.2010)
Published in Microbiology (Society for General Microbiology) (01.02.2010)
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Evaluation of a critical process parameter: Oxygen limitation during cultivation has a fully reversible effect on gene expression of Bordetella pertussis
Streefland, Mathieu, van de Waterbeemd, Bas, Kint, Joeri, van der Pol, Leo A, Beuvery, E. Coen, Tramper, Johannes, Martens, Dirk E
Published in Biotechnology and bioengineering (2009)
Published in Biotechnology and bioengineering (2009)
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