An ALS case with 38 (G4C2)-repeats in the C9orf72 gene shows TDP-43 and sparse dipeptide repeat protein pathology
Dedeene, Lieselot, Van Schoor, Evelien, Race, Valérie, Moisse, Matthieu, Vandenberghe, Rik, Poesen, Koen, Van Damme, Philip, Thal, Dietmar Rudolf
Published in Acta neuropathologica (01.05.2019)
Published in Acta neuropathologica (01.05.2019)
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Journal Article
Distinct molecular patterns of TDP-43 pathology in Alzheimer's disease: relationship with clinical phenotypes
Tomé, Sandra O, Vandenberghe, Rik, Ospitalieri, Simona, Van Schoor, Evelien, Tousseyn, Thomas, Otto, Markus, von Arnim, Christine A F, Thal, Dietmar Rudolf
Published in Acta neuropathologica communications (29.04.2020)
Published in Acta neuropathologica communications (29.04.2020)
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Journal Article
Dipeptide repeat protein and TDP-43 pathology along the hypothalamic–pituitary axis in C9orf72 and non-C9orf72 ALS and FTLD-TDP cases
Dedeene, Lieselot, Van Schoor, Evelien, Ospitalieri, Simona, Ronisz, Alicja, Weishaupt, Jochen H., Otto, Markus, Ludolph, Albert C., Scheuerle, Angelika, Vandenberghe, Rik, Van Damme, Philip, Poesen, Koen, Thal, Dietmar Rudolf
Published in Acta neuropathologica (01.11.2020)
Published in Acta neuropathologica (01.11.2020)
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Journal Article
TUBA4A downregulation as observed in ALS post-mortem motor cortex causes ALS-related abnormalities in zebrafish
Van Schoor, Evelien, Strubbe, Dufie, Braems, Elke, Weishaupt, Jochen, Ludolph, Albert C, Van Damme, Philip, Thal, Dietmar Rudolf, Bercier, Valérie, Van Den Bosch, Ludo
Published in Frontiers in cellular neuroscience (21.02.2024)
Published in Frontiers in cellular neuroscience (21.02.2024)
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Journal Article
Circadian sleep/wake-associated cells show dipeptide repeat protein aggregates in C9orf72-related ALS and FTLD cases
Dedeene, Lieselot, Van Schoor, Evelien, Vandenberghe, Rik, Van Damme, Philip, Poesen, Koen, Thal, Dietmar Rudolf
Published in Acta neuropathologica communications (02.12.2019)
Published in Acta neuropathologica communications (02.12.2019)
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Journal Article
A toxic gain-of-function mechanism in C9orf72 ALS impairs the autophagy-lysosome pathway in neurons
Beckers, Jimmy, Tharkeshwar, Arun Kumar, Fumagalli, Laura, Contardo, Matilde, Van Schoor, Evelien, Fazal, Raheem, Thal, Dietmar Rudolf, Chandran, Siddharthan, Mancuso, Renzo, Van Den Bosch, Ludo, Van Damme, Philip
Published in Acta neuropathologica communications (18.09.2023)
Published in Acta neuropathologica communications (18.09.2023)
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Journal Article
Frontotemporal Lobar Degeneration Case with an N-Terminal TUBA4A Mutation Exhibits Reduced TUBA4A Levels in the Brain and TDP-43 Pathology
Van Schoor, Evelien, Vandenbulcke, Mathieu, Bercier, Valérie, Vandenberghe, Rik, van der Zee, Julie, Van Broeckhoven, Christine, Otto, Markus, Hanseeuw, Bernard, Van Damme, Philip, Van Den Bosch, Ludo, Thal, Dietmar Rudolf
Published in Biomolecules (Basel, Switzerland) (12.03.2022)
Published in Biomolecules (Basel, Switzerland) (12.03.2022)
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Journal Article
Pyroptosis in Alzheimer’s disease: cell type-specific activation in microglia, astrocytes and neurons
Moonen, Sebastiaan, Koper, Marta J., Van Schoor, Evelien, Schaeverbeke, Jolien M., Vandenberghe, Rik, von Arnim, Christine A. F., Tousseyn, Thomas, De Strooper, Bart, Thal, Dietmar Rudolf
Published in Acta neuropathologica (01.02.2023)
Published in Acta neuropathologica (01.02.2023)
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Journal Article
Increased pyroptosis activation in white matter microglia is associated with neuronal loss in ALS motor cortex
Van Schoor, Evelien, Ospitalieri, Simona, Moonen, Sebastiaan, Tomé, Sandra O., Ronisz, Alicja, Ok, Orkun, Weishaupt, Jochen, Ludolph, Albert C., Van Damme, Philip, Van Den Bosch, Ludo, Thal, Dietmar Rudolf
Published in Acta neuropathologica (01.09.2022)
Published in Acta neuropathologica (01.09.2022)
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Journal Article
TSPO Versus P2X7 as a Target for Neuroinflammation: An In Vitro and In Vivo Study
Van Weehaeghe, Donatienne, Van Schoor, Evelien, De Vocht, Joke, Koole, Michel, Attili, Bala, Celen, Sofie, Declercq, Lieven, Thal, Dietmar R, Van Damme, Philip, Bormans, Guy, Van Laere, Koen
Published in Journal of Nuclear Medicine (01.04.2020)
Published in Journal of Nuclear Medicine (01.04.2020)
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Journal Article
HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS
Braems, Elke, Bercier, Valérie, Van Schoor, Evelien, Heeren, Kara, Beckers, Jimmy, Fumagalli, Laura, Dedeene, Lieselot, Moisse, Matthieu, Geudens, Ilse, Hersmus, Nicole, Mehta, Arpan R., Selvaraj, Bhuvaneish T., Chandran, Siddharthan, Ho, Ritchie, Thal, Dietmar R., Van Damme, Philip, Swinnen, Bart, Van Den Bosch, Ludo
Published in Acta neuropathologica (01.09.2022)
Published in Acta neuropathologica (01.09.2022)
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Journal Article
Two distinct molecular patterns of TDP‐43 pathology in cases with Alzheimer’s disease pathology
Tomé, Sandra, Vandenberghe, Rik, Ospitalieri, Simona, Van Schoor, Evelien, Tousseyn, Thomas, Otto, Markus, von Arnim, Christine, Thal, Dietmar Rudolf
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Two distinct molecular patterns of TDP‐43 pathology in cases with Alzheimer’s disease pathology: Human neuropathology/proteinopathies
Tomé, Sandra, Vandenberghe, Rik, Ospitalieri, Simona, Van Schoor, Evelien, Tousseyn, Thomas, Otto, Markus, von Arnim, Christine, Thal, Dietmar Rudolf
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Alzheimer’s disease‐related necroptotic pathology: An exclusive presence of the necrosome in granulovacuolar degeneration inclusions in human and transgenic mouse brains
Koper, Marta J., Van Schoor, Evelien, Ospitalieri, Simona, Vandenberghe, Rik, Vandenbulcke, Mathieu, von Arnim, Christine, Tousseyn, Thomas, Reichwald, Julia, Rabe, Sabine, Staufenbiel, Matthias, Balusu, Sriram, De Strooper, Bart, Thal, Dietmar Rudolf
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
Alzheimer’s disease‐related necroptotic pathology: An exclusive presence of the necrosome in granulovacuolar degeneration inclusions in human and transgenic mouse brains: Molecular and cell biology/neuronal cell death mechanisms (i.e. apoptosis)
Koper, Marta J., Van Schoor, Evelien, Ospitalieri, Simona, Vandenberghe, Rik, Vandenbulcke, Mathieu, von Arnim, Christine, Tousseyn, Thomas, Reichwald, Julia, Rabe, Sabine, Staufenbiel, Matthias, Balusu, Sriram, De Strooper, Bart, Thal, Dietmar Rudolf
Published in Alzheimer's & dementia (01.12.2020)
Published in Alzheimer's & dementia (01.12.2020)
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Journal Article
An ALS case with 38 (G4C2)-repeats in the C9orf72 gene shows TDP-43 and sparse dipeptide repeat protein pathology
Dedeene, Lieselot, Van Schoor, Evelien, Race, Valérie, Moisse, Matthieu, Vandenberghe, Rik, Poesen, Koen, Van Damme, Philip, Thal, Dietmar Rudolf
Published in Acta neuropathologica (01.05.2019)
Published in Acta neuropathologica (01.05.2019)
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