Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM
Woll, Kellie A, Haji-Ghassemi, Omid, Van Petegem, Filip
Published in Nature communications (05.02.2021)
Published in Nature communications (05.02.2021)
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Journal Article
Structural basis for diamide modulation of ryanodine receptor
Ma, Ruifang, Haji-Ghassemi, Omid, Ma, Dan, Jiang, Heng, Lin, Lianyun, Yao, Li, Samurkas, Arthur, Li, Yuxin, Wang, Yiwen, Cao, Peng, Wu, Shian, Zhang, Yan, Murayama, Takashi, Moussian, Bernard, Van Petegem, Filip, Yuchi, Zhiguang
Published in Nature chemical biology (01.11.2020)
Published in Nature chemical biology (01.11.2020)
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Journal Article
Structures of the junctophilin/voltage-gated calcium channel interface reveal hot spot for cardiomyopathy mutations
Yang, Zheng Fang, Panwar, Pankaj, McFarlane, Ciaran R, Tuinte, Wietske E, Campiglio, Marta, Van Petegem, Filip
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2022)
Published in Proceedings of the National Academy of Sciences - PNAS (08.03.2022)
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Journal Article
Cryo-EM structures of the ABCA4 importer reveal mechanisms underlying substrate binding and Stargardt disease
Scortecci, Jessica Fernandes, Molday, Laurie L, Curtis, Susan B, Garces, Fabian A, Panwar, Pankaj, Van Petegem, Filip, Molday, Robert S
Published in Nature communications (08.10.2021)
Published in Nature communications (08.10.2021)
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Journal Article
Crystal structures of ryanodine receptor SPRY1 and tandem-repeat domains reveal a critical FKBP12 binding determinant
Yuchi, Zhiguang, Yuen, Siobhan M Wong King, Lau, Kelvin, Underhill, Ainsley Q, Cornea, Razvan L, Fessenden, James D, Van Petegem, Filip
Published in Nature communications (06.08.2015)
Published in Nature communications (06.08.2015)
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Journal Article
Catecholaminergic polymorphic ventricular tachycardia patients with multiple genetic variants in the PACES CPVT Registry
Roston, Thomas M, Haji-Ghassemi, Omid, LaPage, Martin J, Batra, Anjan S, Bar-Cohen, Yaniv, Anderson, Chris, Lau, Yung R, Maginot, Kathleen, Gebauer, Roman A, Etheridge, Susan P, Potts, James E, Van Petegem, Filip, Sanatani, Shubhayan
Published in PloS one (07.11.2018)
Published in PloS one (07.11.2018)
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Journal Article
RNA Polymerase II transcription independent of TBP in murine embryonic stem cells
Kwan, James Z J, Nguyen, Thomas F, Uzozie, Anuli C, Budzynski, Marek A, Cui, Jieying, Lee, Joseph M C, Van Petegem, Filip, Lange, Philipp F, Teves, Sheila S
Published in eLife (30.03.2023)
Published in eLife (30.03.2023)
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Journal Article
The Cardiac Ryanodine Receptor N-Terminal Region Contains an Anion Binding Site that Is Targeted by Disease Mutations
Kimlicka, Lynn, Tung, Ching-Chieh, Carlsson, Anna-Carin Cecilia, Lobo, Paolo Antonio, Yuchi, Zhiguang, Van Petegem, Filip
Published in Structure (London) (06.08.2013)
Published in Structure (London) (06.08.2013)
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Journal Article
The Deletion of Exon 3 in the Cardiac Ryanodine Receptor Is Rescued by β Strand Switching
Lobo, Paolo A., Kimlicka, Lynn, Tung, Ching-Chieh, Van Petegem, Filip
Published in Structure (London) (08.06.2011)
Published in Structure (London) (08.06.2011)
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Journal Article
A Novel RYR2 Loss-of-Function Mutation (I4855M) is Associated with Left Ventricular Non-compaction and Atypical Catecholaminergic Polymorphic Ventricular Tachycardia
Roston, Thomas M., MD, Guo, Wenting, MSc, Krahn, Andrew D., MD, Wang, Ruiwu, PhD, van Petegem, Filip, PhD, Sanatani, Shubhayan, MD, Chen, S.R. Wayne, PhD, Lehman, Anna, MD
Published in Journal of electrocardiology (01.03.2017)
Published in Journal of electrocardiology (01.03.2017)
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Journal Article
Talin Autoinhibition Is Required for Morphogenesis
Ellis, Stephanie J., Goult, Benjamin T., Fairchild, Michael J., Harris, Nathan J., Long, Jenny, Lobo, Paolo, Czerniecki, Stefan, Van Petegem, Filip, Schöck, Frieder, Peifer, Mark, Tanentzapf, Guy
Published in Current biology (23.09.2013)
Published in Current biology (23.09.2013)
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Journal Article
Characterization of Zebrafish Cardiac and Slow Skeletal Troponin C Paralogs by MD Simulation and ITC
Stevens, Charles M., Rayani, Kaveh, Genge, Christine E., Singh, Gurpreet, Liang, Bo, Roller, Janine M., Li, Cindy, Li, Alison Yueh, Tieleman, D. Peter, van Petegem, Filip, Tibbits, Glen F.
Published in Biophysical journal (12.07.2016)
Published in Biophysical journal (12.07.2016)
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