The effects of inhibition of fatty acid amide hydrolase (FAAH) by JNJ-42165279 in social anxiety disorder: a double-blind, randomized, placebo-controlled proof-of-concept study
Schmidt, Mark E, Liebowitz, Michael R, Stein, Murray B, Grunfeld, Jennifer, Van Hove, Ilse, Simmons, W Kyle, Van Der Ark, Peter, Palmer, James A, Saad, Ziad S, Pemberton, Darrel J, Van Nueten, Luc, Drevets, Wayne C
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2021)
Published in Neuropsychopharmacology (New York, N.Y.) (01.04.2021)
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Translational evaluation of novel selective orexin-1 receptor antagonist JNJ-61393215 in an experimental model for panic in rodents and humans
Salvadore, Giacomo, Bonaventure, Pascal, Shekhar, Anantha, Johnson, Philip L., Lord, Brian, Shireman, Brock T., Lebold, Terry P., Nepomuceno, Diane, Dugovic, Christine, Brooks, Sander, Zuiker, Rob, Bleys, Cathy, Tatikola, Kanaka, Remmerie, Bart, Jacobs, Gabriel E., Schruers, Koen, Moyer, John, Nash, Abigail, Van Nueten, Luc G. M., Drevets, Wayne C.
Published in Translational psychiatry (07.09.2020)
Published in Translational psychiatry (07.09.2020)
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Characterisation of the pharmacodynamic effects of the P2X7 receptor antagonist JNJ-54175446 using an oral dexamphetamine challenge model in healthy males in a randomised, double-blind, placebo-controlled, multiple ascending dose trial
Recourt, Kasper, van der Aart, Jasper, Jacobs, Gabriel, de Kam, Marieke, Drevets, Wayne, van Nueten, Luc, Kanhai, Kawita, Siebenga, Pieter, Zuiker, Rob, Ravenstijn, Paulien, Timmers, Maarten, van Gerven, Joop, de Boer, Peter
Published in Journal of psychopharmacology (Oxford) (01.09.2020)
Published in Journal of psychopharmacology (Oxford) (01.09.2020)
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Long-term safety and tolerability of atabecestat (JNJ-54861911), an oral BACE1 inhibitor, in early Alzheimer's disease spectrum patients: a randomized, double-blind, placebo-controlled study and a two-period extension study
Novak, Gerald, Streffer, Johannes Rolf, Timmers, Maarten, Henley, David, Brashear, H Robert, Bogert, Jennifer, Russu, Alberto, Janssens, Luc, Tesseur, Ina, Tritsmans, Luc, Van Nueten, Luc, Engelborghs, Sebastiaan
Published in Alzheimer's research & therapy (14.05.2020)
Published in Alzheimer's research & therapy (14.05.2020)
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Clinical pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-54175446, a brain permeable P2X7 antagonist, in a randomised single-ascending dose study in healthy participants
Timmers, Maarten, Ravenstijn, Paulien, Xi, Liwen, Triana-Baltzer, Gallen, Furey, Maura, Van Hemelryck, Sandy, Biewenga, Jeike, Ceusters, Marc, Bhattacharya, Anindya, van den Boer, Maarten, van Nueten, Luc, de Boer, Peter
Published in Journal of psychopharmacology (Oxford) (01.12.2018)
Published in Journal of psychopharmacology (Oxford) (01.12.2018)
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The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder
Recourt, Kasper, de Boer, Peter, Zuiker, Rob, Luthringer, Remy, Kent, Justine, van der Ark, Peter, Van Hove, Ilse, van Gerven, Joop, Jacobs, Gabriel, van Nueten, Luc, Drevets, Wayne
Published in Translational psychiatry (03.09.2019)
Published in Translational psychiatry (03.09.2019)
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Journal Article
Characterization of the central nervous system penetrant and selective purine P2X7 receptor antagonist JNJ-54175446 in patients with major depressive disorder
Recourt, Kasper, de Boer, Peter, van der Ark, Peter, Benes, Heike, van Gerven, Joop M. A., Ceusters, Marc, van Nueten, Luc, Drevets, Wayne C., Bhatacharya, Anindya, Browning, Michael, Jacobs, Gabriel E.
Published in Translational psychiatry (24.07.2023)
Published in Translational psychiatry (24.07.2023)
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The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia
Brooks, Sander, Jacobs, Gabriël E, de Boer, Peter, Kent, Justine M, Van Nueten, Luc, van Amerongen, Guido, Zuiker, Rob, Kezic, Iva, Luthringer, Remy, van der Ark, Peter, van Gerven, Joop Ma, Drevets, Wayne
Published in Journal of psychopharmacology (Oxford) (01.02.2019)
Published in Journal of psychopharmacology (Oxford) (01.02.2019)
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Pharmacodynamics of atabecestat (JNJ-54861911), an oral BACE1 inhibitor in patients with early Alzheimer's disease: randomized, double-blind, placebo-controlled study
Timmers, Maarten, Streffer, Johannes Rolf, Russu, Alberto, Tominaga, Yushin, Shimizu, Hiroko, Shiraishi, Ayako, Tatikola, Kanaka, Smekens, Pascale, Börjesson-Hanson, Anne, Andreasen, Niels, Matias-Guiu, Jorge, Baquero, Miquel, Boada, Mercè, Tesseur, Ina, Tritsmans, Luc, Van Nueten, Luc, Engelborghs, Sebastiaan
Published in Alzheimer's research & therapy (23.08.2018)
Published in Alzheimer's research & therapy (23.08.2018)
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Validation of a novel Montreal Cognitive Assessment scoring algorithm in non-demented Parkinson’s disease patients
Sulzer, Patricia, Becker, Sara, Maetzler, Walter, Kalbe, Elke, van Nueten, Luc, Timmers, Maarten, Machetanz, Gerrit, Streffer, Johannes, Salvadore, Giacomo, Scholz, Erich, Tkaczynska, Zuzanna, Brockmann, Kathrin, Berg, Daniela, Liepelt-Scarfone, Inga
Published in Journal of neurology (01.09.2018)
Published in Journal of neurology (01.09.2018)
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Time Trends of Cerebrospinal Fluid Biomarkers of Neurodegeneration in Idiopathic Normal Pressure Hydrocephalus
Lukkarinen, Heikki, Tesseur, Ina, Pemberton, Darrel, Van Der Ark, Peter, Timmers, Maarten, Slemmon, Randy, Janssens, Luc, Streffer, Johannes, Van Nueten, Luc, Bottelbergs, Astrid, Rauramaa, Tuomas, Koivisto, Anne M., Herukka, Sanna-Kaisa, Korhonen, Ville E., Junkkari, Antti, Hiltunen, Mikko, Engelborghs, Sebastiaan, Blennow, Kaj, Zetterberg, Henrik, Kolb, Hartmuth C., Leinonen, Ville
Published in Journal of Alzheimer's disease (01.01.2021)
Published in Journal of Alzheimer's disease (01.01.2021)
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BACE1 Dynamics Upon Inhibition with a BACE Inhibitor and Correlation to Downstream Alzheimer’s Disease Markers in Elderly Healthy Participants
Timmers, Maarten, Barão, Soraia, Van Broeck, Bianca, Tesseur, Ina, Slemmon, John, De Waepenaert, Katja, Bogert, Jennifer, Shaw, Leslie M., Engelborghs, Sebastiaan, Moechars, Dieder, Mercken, Marc, Van Nueten, Luc, Tritsmans, Luc, de Strooper, Bart, Streffer, Johannes Rolf
Published in Journal of Alzheimer's disease (01.01.2017)
Published in Journal of Alzheimer's disease (01.01.2017)
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Multiple daytime administration of the selective orexin-2 receptor antagonist JNJ-42847922 induces somnolence in healthy subjects without residual central effects
van der Ark, Peter D, Golor, Georg, van Nueten, Luc, Nandy, Partha, de Boer, Peter
Published in Journal of psychopharmacology (Oxford) (01.12.2018)
Published in Journal of psychopharmacology (Oxford) (01.12.2018)
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F13. Safety, Tolerability, Pharmacokinetic and Pharmacodynamic Properties of the Selective Orexin-1 Receptor Antagonist JNJ-61393215: Results From the First-In-Human and Multiple Ascending Dose Studies
Salvadore, Giacomo, Brooks, Sander, Cathy, Bleys, Moyer, John, Shireman, Brock, Bonaventure, Pascal, Remmerie, Bart, Tatikola, Kanaka, Jacobs, Gabriel, van Nueten, Luc, Drevets, Wayne
Published in Biological psychiatry (1969) (01.05.2019)
Published in Biological psychiatry (1969) (01.05.2019)
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Executive Function Is Related to the Urinary Urgency in Non-demented Patients With Parkinson's Disease
Tkaczynska, Zuzanna, Becker, Sara, Maetzler, Walter, Timmers, Maarten, Van Nueten, Luc, Sulzer, Patricia, Salvadore, Giacomo, Schäffer, Eva, Brockmann, Kathrin, Streffer, Johannes, Berg, Daniela, Liepelt-Scarfone, Inga
Published in Frontiers in aging neuroscience (06.03.2020)
Published in Frontiers in aging neuroscience (06.03.2020)
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18F-PBR111 PET Imaging in Healthy Controls and Schizophrenia: Test-Retest Reproducibility and Quantification of Neuroinflammation
Ottoy, Julie, De Picker, Livia, Verhaeghe, Jeroen, Deleye, Steven, Wyffels, Leonie, Kosten, Lauren, Sabbe, Bernard, Coppens, Violette, Timmers, Maarten, van Nueten, Luc, Ceyssens, Sarah, Stroobants, Sigrid, Morrens, Manuel, Staelens, Steven
Published in The Journal of nuclear medicine (1978) (01.08.2018)
Published in The Journal of nuclear medicine (1978) (01.08.2018)
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Evaluating Potential QT Effects of JNJ-54861911, a BACE Inhibitor in Single- and Multiple-Ascending Dose Studies, and a Thorough QT Trial With Additional Retrospective Confirmation, Using Concentration-QTc Analysis
Timmers, Maarten, Sinha, Vikash, Darpo, Borje, Smith, Brian, Brown, Randy, Xue, Hongqi, Ferber, Georg, Streffer, Johannes, Russu, Alberto, Tritsmans, Luc, Solanki, Bhavna, Bogert, Jennifer, Van Nueten, Luc, Salvadore, Giacomo, Nandy, Partha
Published in Journal of clinical pharmacology (01.07.2018)
Published in Journal of clinical pharmacology (01.07.2018)
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Correction to: The selective orexin-2 antagonist seltorexant (JNJ-42847922/MIN-202) shows antidepressant and sleep-promoting effects in patients with major depressive disorder
Recourt, Kasper, de Boer, Peter, Zuiker, Rob, Luthringer, Remy, Kent, Justine, van der Ark, Peter, Van Hove, Ilse, van Gerven, Joop, Jacobs, Gabriel, van Nueten, Luc, Drevets, Wayne
Published in Translational psychiatry (02.10.2019)
Published in Translational psychiatry (02.10.2019)
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Profiling classical neuropsychiatric biomarkers across biological fluids and following continuous lumbar puncture: A guide to sample type and time
Triana-Baltzer, Gallen, Timmers, Maarten, De Boer, Peter, Schoene, Manja, Furey, Maura, Bleys, Cathy, Vrancken, Isabeau, Slemmon, Randy, Ceusters, Marc, van Nueten, Luc, Kolb, Hartmuth
Published in Comprehensive Psychoneuroendocrinology (Online) (01.05.2022)
Published in Comprehensive Psychoneuroendocrinology (Online) (01.05.2022)
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Neuroendocrine and Inflammatory Effects of Childhood Trauma Following Psychosocial and Inflammatory Stress in Women with Remitted Major Depressive Disorder
Cassiers, Laura L M, Niemegeers, Peter, Fransen, Erik, Morrens, Manuel, De Boer, Peter, Van Nueten, Luc, Claes, Stephan, Sabbe, Bernard G C, Van Den Eede, Filip
Published in Brain sciences (13.12.2019)
Published in Brain sciences (13.12.2019)
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