PIAS1 Promotes Lymphomagenesis through MYC Upregulation
Rabellino, Andrea, Melegari, Margherita, Tompkins, Van S., Chen, Weina, Van Ness, Brian G., Teruya-Feldstein, Julie, Conacci-Sorrell, Maralice, Janz, Siegfried, Scaglioni, Pier Paolo
Published in Cell reports (Cambridge) (07.06.2016)
Published in Cell reports (Cambridge) (07.06.2016)
Get full text
Journal Article
secDrug: a pipeline to discover novel drug combinations to kill drug-resistant multiple myeloma cells using a greedy set cover algorithm and single-cell multi-omics
Kumar, Harish, Mazumder, Suman, Chakravarti, Sayak, Sharma, Neeraj, Mukherjee, Ujjal Kumar, Kumar, Shaji, Baughn, Linda B, Van Ness, Brian G, Mitra, Amit Kumar
Published in Blood cancer journal (New York) (09.03.2022)
Published in Blood cancer journal (New York) (09.03.2022)
Get full text
Journal Article
Antitumor Activity of the Investigational Proteasome Inhibitor MLN9708 in Mouse Models of B-cell and Plasma Cell Malignancies
LEE, Edmund C, FITZGERALD, Michael, PICKARD, Michael, ZHI LI, TAYBER, Olga, PING LI, HALES, Paul, CARSILLO, Mary, NEPPALLI, Vishala T, BERGER, Allison J, KUPPERMAN, Erik, MANFREDI, Mark, BANNERMAN, Bret, BOLEN, Joseph B, NESS, Brian Van, JANZ, Siegfried, DONELAN, Jill, BANO, Kristen, TERKELSEN, Jennifer, BRADLEY, Daniel P, SUBAKAN, Ozlem, SILVA, Matthew D, LIU, Ray
Published in Clinical cancer research (01.12.2011)
Published in Clinical cancer research (01.12.2011)
Get full text
Journal Article
In vitro and ex vivo gene expression profiling reveals differential kinetic response of HSPs and UPR genes is associated with PI resistance in multiple myeloma
Mitra, Amit Kumar, Kumar, Harish, Ramakrishnan, Vijay, Chen, Li, Baughn, Linda, Kumar, Shaji, Rajkumar, S Vincent, Van Ness, Brian G
Published in Blood cancer journal (New York) (28.07.2020)
Published in Blood cancer journal (New York) (28.07.2020)
Get full text
Journal Article
Profiling bortezomib resistance identifies secondary therapies in a mouse myeloma model
Stessman, Holly A F, Baughn, Linda B, Sarver, Aaron, Xia, Tian, Deshpande, Raamesh, Mansoor, Aatif, Walsh, Susan A, Sunderland, John J, Dolloff, Nathan G, Linden, Michael A, Zhan, Fenghuang, Janz, Siegfried, Myers, Chad L, Van Ness, Brian G
Published in Molecular cancer therapeutics (01.06.2013)
Published in Molecular cancer therapeutics (01.06.2013)
Get full text
Journal Article
Single-Cell Proteomics and Tumor RNAseq Identify Novel Pathways Associated With Clofazimine Sensitivity in PI- and IMiD- Resistant Myeloma, and Putative Stem-Like Cells
Kumar, Harish, Mazumder, Suman, Sharma, Neeraj, Chakravarti, Sayak, Long, Mark D, Meurice, Nathalie, Petit, Joachim, Liu, Song, Chesi, Marta, Sanyal, Sabyasachi, Stewart, A Keith, Kumar, Shaji, Bergsagel, Leif, Rajkumar, S Vincent, Baughn, Linda B, Van Ness, Brian G, Mitra, Amit Kumar
Published in Frontiers in oncology (11.05.2022)
Published in Frontiers in oncology (11.05.2022)
Get full text
Journal Article
Phenotypic and functional characterization of a bortezomib-resistant multiple myeloma cell line by flow and mass cytometry
Baughn, Linda B., Sachs, Zohar, Noble-Orcutt, Klara E., Mitra, Amit, Van Ness, Brian G., Linden, Michael A.
Published in Leukemia & lymphoma (03.08.2017)
Published in Leukemia & lymphoma (03.08.2017)
Get full text
Journal Article
Applications and limitations in translating genomics to clinical practice
Van Ness, Brian
Published in Translational research : the journal of laboratory and clinical medicine (01.02.2016)
Published in Translational research : the journal of laboratory and clinical medicine (01.02.2016)
Get full text
Journal Article
Discovering genetic interactions bridging pathways in genome-wide association studies
Fang, Gang, Wang, Wen, Paunic, Vanja, Heydari, Hamed, Costanzo, Michael, Liu, Xiaoye, Liu, Xiaotong, VanderSluis, Benjamin, Oately, Benjamin, Steinbach, Michael, Van Ness, Brian, Schadt, Eric E, Pankratz, Nathan D, Boone, Charles, Kumar, Vipin, Myers, Chad L
Published in Nature communications (19.09.2019)
Published in Nature communications (19.09.2019)
Get full text
Journal Article
Glutaminase inhibitor CB-839 synergizes with carfilzomib in resistant multiple myeloma cells
Thompson, Ravyn M, Dytfeld, Dominik, Reyes, Leticia, Robinson, Reeder M, Smith, Brittany, Manevich, Yefim, Jakubowiak, Andrzej, Komarnicki, Mieczyslaw, Przybylowicz-Chalecka, Anna, Szczepaniak, Tomasz, Mitra, Amit K, Van Ness, Brian G, Luczak, Magdalena, Dolloff, Nathan G
Published in Oncotarget (30.05.2017)
Published in Oncotarget (30.05.2017)
Get full text
Journal Article
Understanding Drug Sensitivity and Tackling Resistance in Cancer
Tyner, Jeffrey W, Haderk, Franziska, Kumaraswamy, Anbarasu, Baughn, Linda B, Van Ness, Brian, Liu, Song, Marathe, Himangi, Alumkal, Joshi J, Bivona, Trever G, Chan, Keith Syson, Druker, Brian J, Hutson, Alan D, Nelson, Peter S, Sawyers, Charles L, Willey, Christopher D
Published in Cancer research (Chicago, Ill.) (15.04.2022)
Published in Cancer research (Chicago, Ill.) (15.04.2022)
Get full text
Journal Article
Managing incidental findings and research results in genomic research involving biobanks and archived data sets
Wolf, Susan M, Crock, Brittney N, Van Ness, Brian, Lawrenz, Frances, Kahn, Jeffrey P, Beskow, Laura M, Cho, Mildred K, Christman, Michael F, Green, Robert C, Hall, Ralph, Illes, Judy, Keane, Moira, Knoppers, Bartha M, Koenig, Barbara A, Kohane, Isaac S, Leroy, Bonnie, Maschke, Karen J, McGeveran, William, Ossorio, Pilar, Parker, Lisa S, Petersen, Gloria M, Richardson, Henry S, Scott, Joan A, Terry, Sharon F, Wilfond, Benjamin S, Wolf, Wendy A
Published in Genetics in medicine (01.04.2012)
Published in Genetics in medicine (01.04.2012)
Get full text
Journal Article
Molecular signatures of multiple myeloma progression through single cell RNA-Seq
Jang, Jin Sung, Li, Ying, Mitra, Amit Kumar, Bi, Lintao, Abyzov, Alexej, van Wijnen, Andre J, Baughn, Linda B, Van Ness, Brian, Rajkumar, Vincent, Kumar, Shaji, Jen, Jin
Published in Blood cancer journal (New York) (03.01.2019)
Published in Blood cancer journal (New York) (03.01.2019)
Get full text
Journal Article
A transgenic mouse model of plasma cell malignancy shows phenotypic, cytogenetic, and gene expression heterogeneity similar to human multiple myeloma
BOYLAN, Kristin L. M, GOSSE, Mary A, STAGGS, Sarah E, JANZ, Siegfried, GRINDLE, Suzanne, KANSAS, Geoffrey S, VAN NESS, Brian G
Published in Cancer research (Chicago, Ill.) (01.05.2007)
Published in Cancer research (Chicago, Ill.) (01.05.2007)
Get full text
Journal Article
Managing Incidental Findings in Human Subjects Research: Analysis and Recommendations
Wolf, Susan M., Lawrenz, Frances P., Nelson, Charles A., Kahn, Jeffrey P., Cho, Mildred K., Clayton, Ellen Wright, Fletcher, Joel G., Georgieff, Michael K., Hammerschmidt, Dale, Hudson, Kathy, Illes, Judy, Kapur, Vivek, Keane, Moira A., Koenig, Barbara A., LeRoy, Bonnie S., McFarland, Elizabeth G., Paradise, Jordan, Parker, Lisa S., Terry, Sharon F., Van Ness, Brian, Wilfond, Benjamin S.
Published in The Journal of law, medicine & ethics (22.06.2008)
Published in The Journal of law, medicine & ethics (22.06.2008)
Get full text
Journal Article
Clinical and biologic implications of recurrent genomic aberrations in myeloma
Fonseca, Rafael, Blood, Emily, Rue, Montserrat, Harrington, David, Oken, Martin M., Kyle, Robert A., Dewald, Gordon W., Van Ness, Brian, Van Wier, Scott A., Henderson, Kimberly J., Bailey, Richard J., Greipp, Philip R.
Published in Blood (01.06.2003)
Published in Blood (01.06.2003)
Get full text
Journal Article
High-order SNP combinations associated with complex diseases: efficient discovery, statistical power and functional interactions
Fang, Gang, Haznadar, Majda, Wang, Wen, Yu, Haoyu, Steinbach, Michael, Church, Timothy R, Oetting, William S, Van Ness, Brian, Kumar, Vipin
Published in PloS one (19.04.2012)
Published in PloS one (19.04.2012)
Get full text
Journal Article