A lung tropic AAV vector improves survival in a mouse model of surfactant B deficiency
Kang, Martin H., van Lieshout, Laura P., Xu, Liqun, Domm, Jakob M., Vadivel, Arul, Renesme, Laurent, Mühlfeld, Christian, Hurskainen, Maria, Mižíková, Ivana, Pei, Yanlong, van Vloten, Jacob P., Thomas, Sylvia P., Milazzo, Claudia, Cyr-Depauw, Chanèle, Whitsett, Jeffrey A., Nogee, Lawrence M., Wootton, Sarah K., Thébaud, Bernard
Published in Nature communications (06.08.2020)
Published in Nature communications (06.08.2020)
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Journal Article
A promoterless AAV6.2FF-based lung gene editing platform for the correction of surfactant protein B deficiency
Thomas, Sylvia P., Domm, Jakob M., van Vloten, Jacob P., Xu, Liqun, Vadivel, Arul, Yates, Jacob G.E., Pei, Yanlong, Ingrao, Joelle, van P. Lieshout, Laura, Jackson, Sergio R., Minott, Jessica A., Achuthan, Adithya, Mehrani, Yeganeh, McAusland, Thomas M., Zhang, Wei, Karimi, Khalil, Vaughan, Andrew E., de Jong, Jondavid, Kang, Martin H., Thebaud, Bernard, Wootton, Sarah K.
Published in Molecular therapy (06.12.2023)
Published in Molecular therapy (06.12.2023)
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Journal Article
Patients’ and professionals’ perspectives on implementation of opportunistic salpingectomy: a mixed-method study
Gelderblom, Malou E, Van Lieshout, Laura A. M, Piek, Jurgen M. J, De Hullu, Joanne A, Hermens, Rosella P. M. G
Published in BMC health services research (25.07.2021)
Published in BMC health services research (25.07.2021)
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Journal Article
Primary prevention of ovarian cancer: a patient decision aid for opportunistic salpingectomy
van Lieshout, Laura A.M., Gelderblom, Malou E., de Hullu, Joanne A., The, Regina, van Ginkel, Alexandra A., Oerlemans, Anke J.M., Smeets, Kirsten M.W.H., Schreurs, Malou P.H., Piek, Jurgen M.J., Hermens, Rosella P.M.G.
Published in American journal of obstetrics and gynecology (01.02.2022)
Published in American journal of obstetrics and gynecology (01.02.2022)
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Journal Article
Signal Transduction Pathway Activity in High-Grade, Serous Ovarian Carcinoma Reveals a More Favorable Prognosis in Tumors with Low PI3K and High NF-κB Pathway Activity: A Novel Approach to a Long-Standing Enigma
van Lieshout, Laura, van de Stolpe, Anja, van der Ploeg, Phyllis, Bowtell, David, de Hullu, Joanne, Piek, Jurgen
Published in Cancers (18.09.2020)
Published in Cancers (18.09.2020)
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Journal Article
Functional estrogen receptor signaling pathway activity in high-grade serous ovarian carcinoma as compared to estrogen receptor protein expression by immunohistochemistry
van der Ploeg, Phyllis, van Lieshout, Laura A. M., van de Stolpe, Anja, Bosch, Steven L., Lentjes-Beer, Marjolein H. F. M., Bekkers, Ruud L. M., Piek, Jurgen M. J.
Published in Cellular oncology (Dordrecht) (01.08.2021)
Published in Cellular oncology (Dordrecht) (01.08.2021)
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Journal Article
AAV vector distribution in the mouse respiratory tract following four different methods of administration
Santry, Lisa A, Ingrao, Joelle C, Yu, Darrick L, de Jong, Jondavid G, van Lieshout, Laura P, Wood, Geoffrey A, Wootton, Sarah K
Published in BMC biotechnology (15.05.2017)
Published in BMC biotechnology (15.05.2017)
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Journal Article
A Novel Triple-Mutant AAV6 Capsid Induces Rapid and Potent Transgene Expression in the Muscle and Respiratory Tract of Mice
van Lieshout, Laura P, Domm, Jakob M, Rindler, Tara N, Frost, Kathy L, Sorensen, Debra L, Medina, Sarah J, Booth, Stephanie A, Bridges, James P, Wootton, Sarah K
Published in Molecular therapy. Methods & clinical development (15.06.2018)
Published in Molecular therapy. Methods & clinical development (15.06.2018)
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Journal Article
AAV Vectors Pseudotyped with Capsids from Porcine and Bovine Species Mediate In Vitro and In Vivo Gene Delivery
Yu, Darrick L, van Lieshout, Laura P, Stevens, Brenna A Y, Near, Kelsie J Jagt, Stodola, Jenny K, Stinson, Kevin J, Slavic, Durda, Wootton, Sarah K
Published in Viruses (29.12.2023)
Published in Viruses (29.12.2023)
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Journal Article
Factors influencing decision-making around opportunistic salpingectomy: a nationwide survey
Steenbeek, Miranda P, van Lieshout, Laura A M, Aarts, Johanna W M, Piek, Jurgen M J, Coppus, Sjors F P J, Massuger, Leon F A G, Hermens, Rosella P M G, de Hullu, Joanne A
Published in Journal of gynecologic oncology (01.01.2019)
Published in Journal of gynecologic oncology (01.01.2019)
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Journal Article
A novel dual-plasmid platform provides scalable transfection yielding improved productivity and packaging across multiple AAV serotypes and genomes
van Lieshout, Laura P., Rubin, Miranda, Costa-Grant, Katrina, Ota, Stacy, Golebiowski, Diane, Panico, Troy, Wiberg, Eli, Szymczak, Klaudia, Gilmore, Richard, Stanvick, Marissa, Burnham, Brenda, Gagnon, Jeff, Iwuchukwu, Ifeyinwa, Yang, Guang, Ghazi, Iraj, Meola, Alex, Dickerson, Ryan, Thiers, Thomas, Mustich, Luke, Hayes, April, Rivas, Israel, Lotterhand, Jason, Avila, Nancy, McGivney, James, Yin, Jin, Kelly, Tim
Published in Molecular therapy. Methods & clinical development (08.06.2023)
Published in Molecular therapy. Methods & clinical development (08.06.2023)
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Journal Article
AAV-monoclonal antibody expression protects mice from Ebola virus without impeding the endogenous antibody response to heterologous challenge
van Lieshout, Laura P., Rghei, Amira D., Cao, Wenguang, He, Shihua, Soule, Geoff, Zhu, Wenjun, Thomas, Sylvia P., Sorensen, Debra, Frost, Kathy, Tierney, Kevin, Thompson, Brad, Booth, Stephanie, Safronetz, David, Kulkarni, Raveendra R., Bridle, Byram W., Qiu, Xiangguo, Banadyga, Logan, Wootton, Sarah K.
Published in Molecular therapy. Methods & clinical development (08.09.2022)
Published in Molecular therapy. Methods & clinical development (08.09.2022)
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Journal Article
AAV Vectored Immunoprophylaxis for Filovirus Infections
Rghei, Amira D., van Lieshout, Laura P., Santry, Lisa A., Guilleman, Matthew M., Thomas, Sylvia P., Susta, Leonardo, Karimi, Khalil, Bridle, Byram W., Wootton, Sarah K.
Published in Tropical medicine and infectious disease (09.11.2020)
Published in Tropical medicine and infectious disease (09.11.2020)
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Journal Article
The U3 and Env Proteins of Jaagsiekte Sheep Retrovirus and Enzootic Nasal Tumor Virus Both Contribute to Tissue Tropism
Rosales Gerpe, María C, van Lieshout, Laura P, Domm, Jakob M, Ingrao, Joelle C, Datu, Jodre, Walsh, Scott R, Yu, Darrick L, Jong, Jondavid de, Krell, Peter J, Wootton, Sarah K
Published in Viruses (14.11.2019)
Published in Viruses (14.11.2019)
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Journal Article
Safety and Tolerability of the Adeno-Associated Virus Vector, AAV6.2FF, Expressing a Monoclonal Antibody in Murine and Ovine Animal Models
Rghei, Amira D., van Lieshout, Laura P., McLeod, Benjamin M., Pei, Yanlong, Lopes, Jordyn A., Zielinska, Nicole, Baracuhy, Enzo M., Stevens, Brenna A. Y., Thomas, Sylvia P., Yates, Jacob G. E., Warner, Bryce M., Kobasa, Darwyn, Fausther-Bovendo, Hugues, Kobinger, Gary P., Karimi, Khalil, Thompson, Brad, Bridle, Byram W., Susta, Leonardo, Wootton, Sarah K.
Published in Biomedicines (09.09.2021)
Published in Biomedicines (09.09.2021)
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Journal Article
AAV-Mediated Gene Delivery to the Lung
van Lieshout, Laura P, Domm, Jakob M, Wootton, Sarah K
Published in Methods in molecular biology (Clifton, N.J.) (2019)
Published in Methods in molecular biology (Clifton, N.J.) (2019)
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Journal Article
Hysterectomy with opportunistic salpingectomy versus hysterectomy alone
van Lieshout, Laura A M, Steenbeek, Miranda P, De Hullu, Joanne A, Vos, M Caroline, Houterman, Saskia, Wilkinson, Jack, Piek, Jurgen Mj
Published in Cochrane database of systematic reviews (28.08.2019)
Published in Cochrane database of systematic reviews (28.08.2019)
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Journal Article
AAV-mediated delivery of actoxumab and bezlotoxumab results in serum and mucosal antibody concentrations that provide protection from C. difficile toxin challenge
Guilleman, Matthew M., Stevens, Brenna A. Y., Van Lieshout, Laura P., Rghei, Amira D., Pei, Yanlong, Santry, Lisa A., Thompson, Brad, Wootton, Sarah K.
Published in Gene therapy (01.05.2023)
Published in Gene therapy (01.05.2023)
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Journal Article
Engineered AAV8 capsid acquires heparin and AVB sepharose binding capacity but has altered in vivo transduction efficiency
van Lieshout, Laura P., Stegelmeier, Ashley A., Rindler, Tara N., Lawder, John J., Sorensen, Debra L., Frost, Kathy L., Booth, Stephanie A., Bridges, James P., Wootton, Sarah K.
Published in Gene therapy (01.04.2023)
Published in Gene therapy (01.04.2023)
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Journal Article
Intramuscular Adeno-Associated Virus-Mediated Expression of Monoclonal Antibodies Provides 100% Protection Against Ebola Virus Infection in Mice
van Lieshout, Laura P, Soule, Geoff, Sorensen, Debra, Frost, Kathy L, He, Shihua, Tierney, Kevin, Safronetz, David, Booth, Stephanie A, Kobinger, Gary P, Qiu, Xiangguo, Wootton, Sarah K
Published in The Journal of infectious diseases (05.03.2018)
Published in The Journal of infectious diseases (05.03.2018)
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Journal Article