SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington's Disease Models
Quinti, Luisa, Casale, Malcolm, Moniot, Sébastien, Pais, Teresa F., Van Kanegan, Michael J., Kaltenbach, Linda S., Pallos, Judit, Lim, Ryan G., Naidu, Sharadha Dayalan, Runne, Heike, Meisel, Lisa, Rauf, Nazifa Abdul, Leyfer, Dmitriy, Maxwell, Michele M., Saiah, Eddine, Landers, John E., Luthi-Carter, Ruth, Abagyan, Ruben, Dinkova-Kostova, Albena T., Steegborn, Clemens, Marsh, J. Lawrence, Lo, Donald C., Thompson, Leslie M., Kazantsev, Aleksey G.
Published in Cell chemical biology (21.07.2016)
Published in Cell chemical biology (21.07.2016)
Get full text
Journal Article
Apolipoprotein E and peptide mimetics modulate inflammation by binding the SET protein and activating protein phosphatase 2A
Christensen, Dale J, Ohkubo, Nobutaka, Oddo, Jessica, Van Kanegan, Michael J, Neil, Jessica, Li, Fengqiao, Colton, Carol A, Vitek, Michael P
Published in The Journal of immunology (1950) (15.02.2011)
Published in The Journal of immunology (1950) (15.02.2011)
Get full text
Journal Article
Dual activities of the anti-cancer drug candidate PBI-05204 provide neuroprotection in brain slice models for neurodegenerative diseases and stroke
Van Kanegan, Michael J, Dunn, Denise E, Kaltenbach, Linda S, Shah, Bijal, He, Dong Ning, McCoy, Daniel D, Yang, Peiying, Peng, Jiangnan, Shen, Li, Du, Lin, Cichewicz, Robert H, Newman, Robert A, Lo, Donald C
Published in Scientific reports (12.05.2016)
Published in Scientific reports (12.05.2016)
Get full text
Journal Article
Clonal derivation of white and brown adipocyte progenitor cell lines from human pluripotent stem cells
West, Michael D, Chang, Ching-Fang, Larocca, Dana, Li, Jie, Jiang, Jianjie, Sim, Pamela, Labat, Ivan, Chapman, Karen B, Wong, Kari E, Nicoll, James, Van Kanegan, Michael J, de Grey, Aubrey D N J, Nasonkin, Igor O, Stahl, Andreas, Sternberg, Hal
Published in Stem cell research & therapy (08.01.2019)
Published in Stem cell research & therapy (08.01.2019)
Get full text
Journal Article
Initial Assessment of Variability of Responses to Toxicants in Donor-Specific Endothelial Colony Forming Cells
Filonov, Daria, Tice, Raymond, Luo, Ruiyan, Grotegut, Chad, Van Kanegan, Michael J, Ludlow, John W, Il'yasova, Dora, Kinev, Alexander
Published in Frontiers in public health (21.12.2018)
Published in Frontiers in public health (21.12.2018)
Get full text
Journal Article
PPARδ activation by bexarotene promotes neuroprotection by restoring bioenergetic and quality control homeostasis
Dickey, Audrey S, Sanchez, Dafne N, Arreola, Martin, Sampat, Kunal R, Fan, Weiwei, Arbez, Nicolas, Akimov, Sergey, Van Kanegan, Michael J, Ohnishi, Kohta, Gilmore-Hall, Stephen K, Flores, April L, Nguyen, Janice M, Lomas, Nicole, Hsu, Cynthia L, Lo, Donald C, Ross, Christopher A, Masliah, Eliezer, Evans, Ronald M, La Spada, Albert R
Published in Science translational medicine (06.12.2017)
Published in Science translational medicine (06.12.2017)
Get more information
Journal Article
Protein Kinase A Anchoring via AKAP150 Is Essential for TRPV1 Modulation by Forskolin and Prostaglandin E2 in Mouse Sensory Neurons
Schnizler, Katrin, Shutov, Leonid P, Van Kanegan, Michael J, Merrill, Michelle A, Nichols, Blake, McKnight, G. Stanley, Strack, Stefan, Hell, Johannes W, Usachev, Yuriy M
Published in The Journal of neuroscience (07.05.2008)
Published in The Journal of neuroscience (07.05.2008)
Get full text
Journal Article
KEAP1-modifying small molecule reveals muted NRF2 signaling responses in neural stem cells from Huntington’s disease patients
Quinti, Luisa, Naidu, Sharadha Dayalan, Träger, Ulrike, Chen, Xiqun, Kegel-Gleason, Kimberly, Llères, David, Connolly, Colúm, Chopra, Vanita, Low, Cho, Moniot, Sébastien, Sapp, Ellen, Tousley, Adelaide R., Vodicka, Petr, Van Kanegan, Michael J., Kaltenbach, Linda S., Crawford, Lisa A., Fuszard, Matthew, Higgins, Maureen, Miller, James R. C., Farmer, Ruth E., Potluri, Vijay, Samajdar, Susanta, Meisel, Lisa, Zhang, Ningzhe, Snyder, Andrew, Stein, Ross, Hersch, Steven M., Ellerby, Lisa M., Weerapana, Eranthie, Schwarzschild, Michael A., Steegborn, Clemens, Leavitt, Blair R., Degterev, Alexei, Tabrizi, Sarah J., Lo, Donald C., DiFiglia, Marian, Thompson, Leslie M., Dinkova-Kostova, Albena T., Kazantsev, Aleksey G.
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2017)
Published in Proceedings of the National Academy of Sciences - PNAS (06.06.2017)
Get full text
Journal Article
Protein Kinase A Anchoring via AKAP150 Is Essential for TRPV1 Modulation by Forskolin and Prostaglandin E 2 in Mouse Sensory Neurons
Schnizler, Katrin, Shutov, Leonid P., Van Kanegan, Michael J., Merrill, Michelle A., Nichols, Blake, McKnight, G. Stanley, Strack, Stefan, Hell, Johannes W., Usachev, Yuriy M.
Published in The Journal of neuroscience (07.05.2008)
Published in The Journal of neuroscience (07.05.2008)
Get full text
Journal Article
Protein Kinase A Anchoring via AKAP150 Is Essential for TRPV1 Modulation by Forskolin and Prostaglandin E sub(2) in Mouse Sensory Neurons
Schnizler, Katrin, Shutov, Leonid P, Van Kanegan, Michael J, Merrill, Michelle A, Nichols, Blake, McKnight, GStanley, Strack, Stefan, Hell, Johannes W, Usachev, Yuriy M
Published in The Journal of neuroscience (07.05.2008)
Get full text
Published in The Journal of neuroscience (07.05.2008)
Journal Article