Comparison of Hepatic 2D Sandwich Cultures and 3D Spheroids for Long-term Toxicity Applications: A Multicenter Study
Bell, Catherine C, Dankers, Anita C A, Lauschke, Volker M, Sison-Young, Rowena, Jenkins, Roz, Rowe, Cliff, Goldring, Chris E, Park, Kevin, Regan, Sophie L, Walker, Tracy, Schofield, Chris, Baze, Audrey, Foster, Alison J, Williams, Dominic P, van de Ven, Amy W M, Jacobs, Frank, Houdt, Jos van, Lähteenmäki, Tuula, Snoeys, Jan, Juhila, Satu, Richert, Lysiane, Ingelman-Sundberg, Magnus
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Published in Toxicological sciences (01.04.2018)
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The ontogeny of drug metabolizing enzymes and transporters in the rat
de Zwart, Loeckie, Scholten, Martijn, Monbaliu, Johan G., Annaert, Pieter P., Van Houdt, Jos M., Van den Wyngaert, Ilse, De Schaepdrijver, Luc M., Bailey, Graham P., Coogan, Timothy P., Coussement, Werner C., Mannens, Geert S.
Published in Reproductive toxicology (Elmsford, N.Y.) (01.11.2008)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.11.2008)
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CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6α-hydroxylase activity in human liver microsomes
Bahadur, Namrata, Leathart, Julian B.S, Mutch, Elaine, Steimel-Crespi, Dorothy, Dunn, Stuart A, Gilissen, Ron, Houdt, Jos Van, Hendrickx, Jan, Mannens, Geert, Bohets, Hilde, Williams, Faith M, Armstrong, Martin, Crespi, Charles L, Daly, Ann K
Published in Biochemical pharmacology (01.12.2002)
Published in Biochemical pharmacology (01.12.2002)
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In vitro studies on the metabolism of trabectedin (YONDELIS ®) in monkey and man, including human CYP reaction phenotyping
Vermeir, Marc, Hemeryck, Alex, Cuyckens, Filip, Francesch, Andres, Bockx, Marc, Van Houdt, Jos, Steemans, Kathleen, Mannens, Geert, Avilés, Pablo, De Coster, Roland
Published in Biochemical pharmacology (15.05.2009)
Published in Biochemical pharmacology (15.05.2009)
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EXPRESSION AND INDUCTION POTENTIAL OF CYTOCHROMES P450 IN HUMAN CRYOPRESERVED HEPATOCYTES
ROYMANS, Dirk, ANNAERT, Pieter, MEULDERMANS, Willem, VAN HOUDT, Jos, WEYGERS, Adri, NOUKENS, Jan, SENSENHAUSER, Carlo, SILVA, José, VAN LOOVEREN, Cis, HENDRICKX, Jan, MANNENS, Geert
Published in Drug metabolism and disposition (01.07.2005)
Published in Drug metabolism and disposition (01.07.2005)
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In vitro Phase I- and Phase II-Drug Metabolism in The Liver of Juvenile and Adult Göttingen Minipigs
Van Peer, Els, Jacobs, Frank, Snoeys, Jan, Van Houdt, Jos, Pijpers, Ils, Casteleyn, Christophe, Van Ginneken, Chris, Van Cruchten, Steven
Published in Pharmaceutical research (01.04.2017)
Published in Pharmaceutical research (01.04.2017)
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In vitro drug metabolism in juvenile non-rodent species: State-of-the-art
Van Peer, Els, Snoeys, Jan, Jacobs, Frank, Van Houdt, Jos, Pijpers, Ils, Casteleyn, Christophe, Van Ginneken, Chris, Van Cruchten, Steven
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2016)
Published in Reproductive toxicology (Elmsford, N.Y.) (01.09.2016)
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studies on the metabolism of trabectedin (YONDELIS) in monkey and man, including human CYP reaction phenotyping
Vermeir, Marc, Hemeryck, Alex, Cuyckens, Filip, Francesch, Andres, Bockx, Marc, van Houdt, Jos, Steemans, Kathleen, Mannens, Geert, Avilés, Pablo, de Coster, Roland
Published in Biochemical pharmacology (09.04.2009)
Published in Biochemical pharmacology (09.04.2009)
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Effect of the fungicide imazalil on hepatic microsomal cytochrome P-450 and cytochrome P-450 dependent activities in the Bobwhite quail (Colinus virginianus)
Lavrijsen, K, Houdt, J. van, Dyck, D. van, Meuldermans, W, Heykants, J
Published in Pesticide science (1990)
Published in Pesticide science (1990)
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CYP2C8 polymorphisms in Caucasians and their relationship with paclitaxel 6alpha-hydroxylase activity in human liver microsomes
Bahadur, Namrata, Leathart, Julian B S, Mutch, Elaine, Steimel-Crespi, Dorothy, Dunn, Stuart A, Gilissen, Ron, Houdt, Jos Van, Hendrickx, Jan, Mannens, Geert, Bohets, Hilde, Williams, Faith M, Armstrong, Martin, Crespi, Charles L, Daly, Ann K
Published in Biochemical pharmacology (01.12.2002)
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Published in Biochemical pharmacology (01.12.2002)
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Induction potential of antifungals containing an imidazole or triazole moiety. Miconazole and ketoconazole, but not itraconazole are able to induce hepatic drug metabolizing enzymes of male rats at high doses
Lavrijsen, K, Van Houdt, J, Thijs, D, Meuldermans, W, Heykants, J
Published in Biochemical pharmacology (01.06.1986)
Published in Biochemical pharmacology (01.06.1986)
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Is the metabolism of alfentanil subject to debrisoquine polymorphism? a study using human liver microsomes
LAVRIJSEN, K. L. M, VAN HOUDT, J. M. G, VAN DYCK, D. M. J, HENDRICKX, J. J. J. M, WOESTENBORGHS, R. J. H, LAUERS, W, MEULDERMANS, W. E. G, HEYKANTS, J. J. P
Published in Anesthesiology (Philadelphia) (01.10.1988)
Published in Anesthesiology (Philadelphia) (01.10.1988)
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In vitro screening for hepatotoxicity of xenobiotics using isolated hepatocytes
Lavrijsen, K, Dijck, D. van, Houdt, J. van, Pelt, I. van, Meuldermans, W, Heykants, J
Published in Alternatives to laboratory animals (01.03.1988)
Published in Alternatives to laboratory animals (01.03.1988)
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