HDAC6 is a therapeutic target in mutant GARS-induced Charcot-Marie-Tooth disease
Benoy, Veronick, Van Helleputte, Lawrence, Prior, Robert, d'Ydewalle, Constantin, Haeck, Wanda, Geens, Natasja, Scheveneels, Wendy, Schevenels, Begga, Cader, M Zameel, Talbot, Kevin, Kozikowski, Alan P, Vanden Berghe, Pieter, Van Damme, Philip, Robberecht, Wim, Van Den Bosch, Ludo
Published in Brain (London, England : 1878) (01.03.2018)
Published in Brain (London, England : 1878) (01.03.2018)
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Journal Article
Inhibition of histone deacetylase 6 (HDAC6) protects against vincristine-induced peripheral neuropathies and inhibits tumor growth
Van Helleputte, Lawrence, Kater, Mandy, Cook, Dana P., Eykens, Caroline, Rossaert, Elisabeth, Haeck, Wanda, Jaspers, Tom, Geens, Natasja, Vanden Berghe, Pieter, Gysemans, Conny, Mathieu, Chantal, Robberecht, Wim, Van Damme, Philip, Cavaletti, Guido, Jarpe, Matthew, Van Den Bosch, Ludo
Published in Neurobiology of disease (01.03.2018)
Published in Neurobiology of disease (01.03.2018)
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Journal Article
Restoration of histone acetylation ameliorates disease and metabolic abnormalities in a FUS mouse model
Rossaert, Elisabeth, Pollari, Eveliina, Jaspers, Tom, Van Helleputte, Lawrence, Jarpe, Matthew, Van Damme, Philip, De Bock, Katrien, Moisse, Matthieu, Van Den Bosch, Ludo
Published in Acta neuropathologica communications (05.07.2019)
Published in Acta neuropathologica communications (05.07.2019)
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Journal Article
Testosterone boosts physical activity in male mice via dopaminergic pathways
Jardí, Ferran, Laurent, Michaël R, Kim, Nari, Khalil, Rougin, De Bundel, Dimitri, Van Eeckhaut, Ann, Van Helleputte, Lawrence, Deboel, Ludo, Dubois, Vanessa, Schollaert, Dieter, Decallonne, Brigitte, Carmeliet, Geert, Van den Bosch, Ludo, D'Hooge, Rudi, Claessens, Frank, Vanderschueren, Dirk
Published in Scientific reports (17.01.2018)
Published in Scientific reports (17.01.2018)
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Journal Article
Impact of prolonged sepsis on neural and muscular components of muscle contractions in a mouse model
Goossens, Chloë, Weckx, Ruben, Derde, Sarah, Van Helleputte, Lawrence, Schneidereit, Dominik, Haug, Michael, Reischl, Barbara, Friedrich, Oliver, Van Den Bosch, Ludo, Van den Berghe, Greet, Langouche, Lies
Published in Journal of cachexia, sarcopenia and muscle (01.04.2021)
Published in Journal of cachexia, sarcopenia and muscle (01.04.2021)
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Journal Article
The role of histone deacetylase 6 (HDAC6) in neurodegeneration
van Helleputte, Lawrence, Benoy, Veronick, van Den Bosch, Ludo
Published in Research and reports in biology (01.01.2014)
Published in Research and reports in biology (01.01.2014)
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Journal Article
Genetic ablation of phospholipase C delta 1 increases survival in SOD1G93A mice
Staats, Kim A, Van Helleputte, Lawrence, Jones, Ashley R, Bento-Abreu, André, Van Hoecke, Annelies, Shatunov, Aleksey, Simpson, Claire L, Lemmens, Robin, Jaspers, Tom, Fukami, Kiyoko, Nakamura, Yoshikazu, Brown, Robert H, Van Damme, Philip, Liston, Adrian, Robberecht, Wim, Al-Chalabi, Ammar, Van Den Bosch, Ludo
Published in Neurobiology of disease (01.12.2013)
Published in Neurobiology of disease (01.12.2013)
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Journal Article
PhAc-ALGP-Dox, a Novel Anticancer Prodrug with Targeted Activation and Improved Therapeutic Index
Casazza, Andrea, Van Helleputte, Lawrence, Van Renterghem, Britt, Pokreisz, Peter, De Geest, Natalie, De Petrini, Marzia, Janssens, Tom, Pellens, Marijke, Diricx, Marjan, Riera-Domingo, Carla, Wozniak, Agnieszka, Mazzone, Massimiliano, Schöffski, Patrick, Defert, Olivier, Reyns, Geert, Kindt, Nele
Published in Molecular cancer therapeutics (01.04.2022)
Published in Molecular cancer therapeutics (01.04.2022)
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Journal Article
Transcriptional upregulation of myelin components in spontaneous myelin basic protein-deficient mice
Staats, Kim A, Pombal, Diana, Schönefeldt, Susann, Van Helleputte, Lawrence, Maurin, Hervé, Dresselaers, Tom, Govaerts, Kristof, Himmelreich, Uwe, Van Leuven, Fred, Van Den Bosch, Ludo, Dooley, James, Humblet-Baron, Stephanie, Liston, Adrian
Published in Brain research (05.05.2015)
Published in Brain research (05.05.2015)
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Journal Article
Genetic ablation of phospholipase C delta 1 increases survival in SOD1(G93A) mice
Staats, Kim A, Van Helleputte, Lawrence, Jones, Ashley R, Bento-Abreu, André, Van Hoecke, Annelies, Shatunov, Aleksey, Simpson, Claire L, Lemmens, Robin, Jaspers, Tom, Fukami, Kiyoko, Nakamura, Yoshikazu, Brown, Jr, Robert H, Van Damme, Philip, Liston, Adrian, Robberecht, Wim, Al-Chalabi, Ammar, Van Den Bosch, Ludo
Published in Neurobiology of disease (01.12.2013)
Published in Neurobiology of disease (01.12.2013)
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Journal Article
COMPOUNDS COMPRISING A TETRAPEPTIDIC MOIETY
DEFERT, Olivier, CASAZZA, Andrea, REYNS, Geert, VAN HELLEPUTTE, Lawrence, KINDT, Nele
Year of Publication 12.09.2024
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Year of Publication 12.09.2024
Patent
COMPOUNDS COMPRISING A TETRAPEPTIDIC MOIETY
DEFERT, Olivier, CASAZZA, Andrea, REYNS, Geert, VAN HELLEPUTTE, Lawrence, KINDT, Nele
Year of Publication 01.11.2023
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Year of Publication 01.11.2023
Patent
COMPOUNDS COMPRISING A TETRAPEPTIDIC MOIETY
DEFERT, Olivier, CASAZZA, Andrea, REYNS, Geert, VAN HELLEPUTTE, Lawrence, KINDT, Nele
Year of Publication 03.08.2023
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Year of Publication 03.08.2023
Patent
COMPOUNDS COMPRISING A TETRAPEPTIDIC MOIETY
DEFERT, Olivier, CASAZZA, Andrea, REYNS, Geert, VAN HELLEPUTTE, Lawrence, KINDT, Nele
Year of Publication 11.08.2022
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Year of Publication 11.08.2022
Patent
COMPOUNDS COMPRISING A TETRAPEPTIDIC MOIETY
DEFERT, Olivier, CASAZZA, Andrea, REYNS, Geert, VAN HELLEPUTTE, Lawrence, KINDT, Nele
Year of Publication 30.06.2022
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Year of Publication 30.06.2022
Patent
COMPOUNDS COMPRISING A TETRAPEPTIDIC MOIETY
REYNS, GEERT, DEFERT, OLIVIER, CASAZZA, ANDREA, VAN HELLEPUTTE, LAWRENCE, KINDT, NELE
Year of Publication 30.06.2022
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Year of Publication 30.06.2022
Patent
PYRIMIDINE HYDROXY AMIDE COMPOUNDS FOR TREATING PERIPHERAL NEUROPATHY
VAN HELLEPUTTE LAWRENCE, VAN DEN BOSCH LUDO, JARPE MATTHEW BLAIRE, BENOY VERONICK
Year of Publication 09.06.2016
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Year of Publication 09.06.2016
Patent