Site-Specific, Platform-Based Conjugation Strategy for the Synthesis of Dual-Labeled Immunoconjugates for Bimodal PET/NIRF Imaging of HER2-Positive Tumors
Adumeau, Pierre, Raavé, René, Boswinkel, Milou, Heskamp, Sandra, Wessels, Hans J. C. T, van Gool, Alain J, Moreau, Mathieu, Bernhard, Claire, Da Costa, Laurène, Goncalves, Victor, Denat, Franck
Published in Bioconjugate chemistry (16.03.2022)
Published in Bioconjugate chemistry (16.03.2022)
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Evaluation of cyclooxygenase oxylipins as potential biomarker for obesity-associated adipose tissue inflammation and type 2 diabetes using targeted multiple reaction monitoring mass spectrometry
Tans, Roel, Bande, Rieke, van Rooij, Arno, Molloy, Billy J., Stienstra, Rinke, Tack, Cees J., Wevers, Ron A., Wessels, Hans J.C.T., Gloerich, Jolein, van Gool, Alain J.
Published in Prostaglandins, leukotrienes and essential fatty acids (01.09.2020)
Published in Prostaglandins, leukotrienes and essential fatty acids (01.09.2020)
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Inflammatory cytokine oncostatin M induces endothelial activation in macro- and microvascular endothelial cells and in APOE3Leiden.CETP mice
van Keulen, Danielle, Pouwer, Marianne G, Pasterkamp, Gerard, van Gool, Alain J, Sollewijn Gelpke, Maarten D, Princen, Hans M G, Tempel, Dennie
Published in PloS one (01.10.2018)
Published in PloS one (01.10.2018)
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Primary Focal Segmental Glomerulosclerosis Plasmas Increase Lipid Droplet Formation and Perilipin-2 Expression in Human Podocytes
den Braanker, Dirk J W, Maas, Rutger J H, van Mierlo, Guido, Parr, Naomi M J, Bakker-van Bebber, Marinka, Deegens, Jeroen K J, Jansen, Pascal W T C, Gloerich, Jolein, Willemsen, Brigith, Dijkman, Henry B, van Gool, Alain J, Wetzels, Jack F M, Rinschen, Markus M, Vermeulen, Michiel, Nijenhuis, Tom, van der Vlag, Johan
Published in International journal of molecular sciences (22.12.2022)
Published in International journal of molecular sciences (22.12.2022)
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Plasma glycoproteomics delivers high-specificity disease biomarkers by detecting site-specific glycosylation abnormalities
Wessels, Hans J.C.T., Kulkarni, Purva, van Dael, Maurice, Suppers, Anouk, Willems, Esther, Zijlstra, Fokje, Kragt, Else, Gloerich, Jolein, Schmit, Pierre-Olivier, Pengelley, Stuart, Marx, Kristina, van Gool, Alain J., Lefeber, Dirk J.
Published in Journal of advanced research (01.07.2024)
Published in Journal of advanced research (01.07.2024)
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Qualitative evaluation of coronary atherosclerosis in a large cohort of young and middle-aged Dutch tissue donors implies that coronary thrombo-embolic manifestations are stochastic
Lindeman, Jan H, Hulsbos, Luuk, van den Bogaerdt, Antoon J, Geerts, Marlieke, van Gool, Alain J, Hamming, Jaap F, van Dijk, Rogier A, Schaapherder, Alexander F
Published in PloS one (27.11.2018)
Published in PloS one (27.11.2018)
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Analysis of 953 human proteins from a mitochondrial HEK293 fraction by complexome profiling
Wessels, Hans J C T, Vogel, Rutger O, Lightowlers, Robert N, Spelbrink, Johannes N, Rodenburg, Richard J, van den Heuvel, Lambert P, van Gool, Alain J, Gloerich, Jolein, Smeitink, Jan A M, Nijtmans, Leo G
Published in PloS one (23.07.2013)
Published in PloS one (23.07.2013)
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Genome sequencing and comparison of two nonhuman primate animal models, the cynomolgus and Chinese rhesus macaques
Yan, Guangmei, Wang, Xiaoning, Wang, Jian, Zhang, Guojie, Fang, Xiaodong, Zhang, Yanfeng, Li, Cai, Ling, Fei, Cooper, David N, Li, Qiye, Li, Yan, van Gool, Alain J, Du, Hongli, Chen, Jiesi, Chen, Ronghua, Zhang, Pei, Huang, Zhiyong, Thompson, John R, Meng, Yuhuan, Bai, Yinqi, Wang, Jufang, Zhuo, Min, Wang, Tao, Huang, Ying, Wei, Liqiong, Li, Jianwen, Wang, Zhiwen, Hu, Haofu, Yang, Pengcheng, Le, Liang, Stenson, Peter D, Li, Bo, Liu, Xiaoming, Ball, Edward V, An, Na, Huang, Quanfei, Zhang, Yong, Fan, Wei, Zhang, Xiuqing, Li, Yingrui, Wang, Wen, Katze, Michael G, Su, Bing, Nielsen, Rasmus, Yang, Huanming, Wang, Jun
Published in Nature biotechnology (01.11.2011)
Published in Nature biotechnology (01.11.2011)
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Bridging the translational innovation gap through good biomarker practice
van Gool, Alain J, Bietrix, Florence, Caldenhoven, Eric, Zatloukal, Kurt, Scherer, Andreas, Litton, Jan-Eric, Meijer, Gerrit, Blomberg, Niklas, Smith, Andy, Mons, Barend, Heringa, Jaap, Koot, Wim-Jan, Smit, Martin J, Hajduch, Marian, Rijnders, Ton, Ussi, Anton
Published in Nature reviews. Drug discovery (01.09.2017)
Published in Nature reviews. Drug discovery (01.09.2017)
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Understanding the increased risk of infections in diabetes: innate and adaptive immune responses in type 1 diabetes
Janssen, Anna W.M., Stienstra, Rinke, Jaeger, Martin, van Gool, Alain J., Joosten, Leo A.B., Netea, Mihai G., Riksen, Niels P., Tack, Cees J.
Published in Metabolism, clinical and experimental (01.08.2021)
Published in Metabolism, clinical and experimental (01.08.2021)
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Towards a routine application of Top-Down approaches for label-free discovery workflows
Schmit, Pierre-Olivier, Vialaret, Jerome, Wessels, Hans J.C.T., van Gool, Alain J., Lehmann, Sylvain, Gabelle, Audrey, Wood, Jason, Bern, Marshall, Paape, Rainer, Suckau, Detlev, Kruppa, Gary, Hirtz, Christophe
Published in Journal of proteomics (20.03.2018)
Published in Journal of proteomics (20.03.2018)
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The GlycoPaSER Prototype as a Real-Time N-Glycopeptide Identification Tool Based on the PaSER Parallel Computing Platform
Armony, Gad, Brehmer, Sven, Srikumar, Tharan, Pfennig, Lennard, Zijlstra, Fokje, Trede, Dennis, Kruppa, Gary, Lefeber, Dirk J, van Gool, Alain J, Wessels, Hans J C T
Published in International journal of molecular sciences (26.04.2023)
Published in International journal of molecular sciences (26.04.2023)
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Ten quick tips for building FAIR workflows
de Visser, Casper, Johansson, Lennart F, Kulkarni, Purva, Mei, Hailiang, Neerincx, Pieter, Joeri van der Velde, K, Horvatovich, Péter, van Gool, Alain J, Swertz, Morris A, Hoen, Peter A. C. 't, Niehues, Anna
Published in PLoS computational biology (28.09.2023)
Published in PLoS computational biology (28.09.2023)
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A multi-omics data analysis workflow packaged as a FAIR Digital Object
Niehues, Anna, de Visser, Casper, Hagenbeek, Fiona A, Kulkarni, Purva, Pool, René, Karu, Naama, Kindt, Alida S D, Singh, Gurnoor, Vermeiren, Robert R J M, Boomsma, Dorret I, van Dongen, Jenny, ’t Hoen, Peter A C, van Gool, Alain J
Published in Gigascience (02.01.2024)
Published in Gigascience (02.01.2024)
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The funhouse mirror: the I in personalised healthcare
Vegter, Mira W., Zwart, Hub A. E., van Gool, Alain J.
Published in Life sciences, society and policy (05.01.2021)
Published in Life sciences, society and policy (05.01.2021)
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Metabolomic predictors of phenotypic traits can replace and complement measured clinical variables in population-scale expression profiling studies
Niehues, Anna, Bizzarri, Daniele, Reinders, Marcel J.T, Slagboom, P. Eline, van Gool, Alain J, van den Akker, Erik B, t Hoen, Peter A.C
Published in BMC genomics (31.07.2022)
Published in BMC genomics (31.07.2022)
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Cerebrospinal fluid monocyte chemoattractant protein 1 correlates with progression of Parkinson's disease
Santaella, Anna, Kuiperij, H Bea, van Rumund, Anouke, Esselink, Rianne A J, van Gool, Alain J, Bloem, Bastiaan R, Verbeek, Marcel M
Published in NPJ Parkinson's Disease (03.09.2020)
Published in NPJ Parkinson's Disease (03.09.2020)
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Evaluation of chitotriosidase as a biomarker for adipose tissue inflammation in overweight individuals and type 2 diabetic patients
Tans, Roel, van Diepen, Janna A, Bijlsma, Sabina, Verschuren, Lars, Suppers, Anouk, Stienstra, Rinke, Wevers, Ron A, Tack, Cees J, Gloerich, Jolein, van Gool, Alain J
Published in International Journal of Obesity (01.09.2019)
Published in International Journal of Obesity (01.09.2019)
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