Comparison of ticagrelor and thienopyridine P2Y12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis
van Giezen, J.J.J, Berntsson, Pia, Zachrisson, Helen, Björkman, Jan-Arne
Published in Thrombosis research (01.11.2009)
Published in Thrombosis research (01.11.2009)
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Leveraging Human Genetics to Estimate Clinical Risk Reductions Achievable by Inhibiting Factor XI
Georgi, Benjamin, Mielke, Johanna, Chaffin, Mark, Khera, Amit V, Gelis, Lian, Mundl, Hardi, van Giezen, J.J.J, Ellinor, Patrick, Kathiresan, Sekar, Ziegelbauer, Karl, Freitag, Daniel F
Published in Stroke (1970) (01.11.2019)
Published in Stroke (1970) (01.11.2019)
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Ticagrelor Enhances Adenosine-Induced Coronary Vasodilatory Responses in Humans
Wittfeldt, Ann, MD, Emanuelsson, Håkan, MD, PhD, Brandrup-Wognsen, Gunnar, MD, PhD, van Giezen, J.J.J., PhD, Jonasson, Jenny, PhD, Nylander, Sven, PhD, Gan, Li-Ming, MD, PhD
Published in Journal of the American College of Cardiology (19.02.2013)
Published in Journal of the American College of Cardiology (19.02.2013)
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Ticagrelor binds to human P2Y12 independently from ADP but antagonizes ADP‐induced receptor signaling and platelet aggregation
VAN GIEZEN, J. J. J., NILSSON, L., BERNTSSON, P., WISSING, B.‐M., GIORDANETTO, F., TOMLINSON, W., GREASLEY, P. J.
Published in Journal of thrombosis and haemostasis (01.09.2009)
Published in Journal of thrombosis and haemostasis (01.09.2009)
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Evaluation of ticagrelor pharmacodynamic interactions with reversibly binding or non-reversibly binding P2Y12 antagonists in an ex-vivo canine model
Ravnefjord, Anna, Weilitz, Jessika, Emanuelsson, Britt-Marie, van Giezen, J.J.J
Published in Thrombosis research (01.10.2012)
Published in Thrombosis research (01.10.2012)
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Synthesis, structure–property relationships and pharmacokinetic evaluation of ethyl 6-aminonicotinate sulfonylureas as antagonists of the P2Y12 receptor
Bach, Peter, Boström, Jonas, Brickmann, Kay, van Giezen, J.J.J., Groneberg, Robert D., Harvey, Darren M., O'Sullivan, Michael, Zetterberg, Fredrik
Published in European journal of medicinal chemistry (01.07.2013)
Published in European journal of medicinal chemistry (01.07.2013)
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Gan, Li-Ming, Wittfeldt, Ann, Brandrup-Wognsen, Gunnar, van Giezen, J.J.J., Jonasson, Jenny, Nylander, Sven, Emanuelsson, Håkan
Published in Journal of the American College of Cardiology (01.08.2013)
Published in Journal of the American College of Cardiology (01.08.2013)
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Optimization of ketone-based P2Y12 receptor antagonists as antithrombotic agents: Pharmacodynamics and receptor kinetics considerations
Giordanetto, Fabrizio, Bach, Peter, Zetterberg, Fredrik, Antonsson, Thomas, Bylund, Ruth, Johansson, Johan, Sellén, Mikael, Brown, David, Hideståhl, Lotta, Berntsson, Pia, Hovdal, Daniel, Zachrisson, Helen, Björkman, Jan-Arne, van Giezen, J.J.J.
Published in Bioorganic & medicinal chemistry letters (01.07.2014)
Published in Bioorganic & medicinal chemistry letters (01.07.2014)
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A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y12 receptor
BACH, Peter, BOSTROM, Jonas, BRICKMANN, Kay, VAN GIEZEN, J. J. J, HOVLAND, Ragnar, PETERSSON, Annika U, RAY, Asim, ZETTERBERG, Fredrik
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
Published in Bioorganic & medicinal chemistry letters (15.05.2011)
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Journal Article
Comparison of ticagrelor and thienopyridine P2Y 12 binding characteristics and antithrombotic and bleeding effects in rat and dog models of thrombosis/hemostasis
van Giezen, J.J.J., Berntsson, Pia, Zachrisson, Helen, Björkman, Jan-Arne
Published in Thrombosis research (2009)
Published in Thrombosis research (2009)
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Journal Article
A novel series of piperazinyl-pyridine ureas as antagonists of the purinergic P2Y 12 receptor
Bach, Peter, Boström, Jonas, Brickmann, Kay, van Giezen, J.J.J., Hovland, Ragnar, Petersson, Annika U., Ray, Asim, Zetterberg, Fredrik
Published in Bioorganic & medicinal chemistry letters (2011)
Published in Bioorganic & medicinal chemistry letters (2011)
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Evaluation of platelet function, a method comparison
Nylander, S., Johansson, K., Van Giezen, J.J.J., Lindahl, T.L.
Published in Platelets (Edinburgh) (01.02.2006)
Published in Platelets (Edinburgh) (01.02.2006)
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