Food as a Source for Quorum Sensing Inhibitors: Iberin from Horseradish Revealed as a Quorum Sensing Inhibitor of Pseudomonas aeruginosa
JAKOBSEN, Tim Holm, BRAGASON, Steinn Kristinn, GIVSKOVA, Michael, PHIPPS, Richard Kerry, CHRISTENSEN, Louise Dahl, GENNIP, Maria Van, ALHEDE, Morten, SKINDERSOE, Mette, LARSEN, Thomas Ostenfeld, HØIBY, Niels, BJARNSHOLT, Thomas
Published in Applied and Environmental Microbiology (01.04.2012)
Published in Applied and Environmental Microbiology (01.04.2012)
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Clearance of Pseudomonas aeruginosa Foreign-Body Biofilm Infections through Reduction of the Cyclic Di-GMP Level in the Bacteria
Christensen, Louise D., van Gennip, Maria, Rybtke, Morten T., Wu, Hong, Chiang, Wen-Chi, Alhede, Morten, Høiby, Niels, Nielsen, Thomas E., Givskov, Michael, Tolker-Nielsen, Tim
Published in Infection and Immunity (01.08.2013)
Published in Infection and Immunity (01.08.2013)
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Interactions between Polymorphonuclear Leukocytes and Pseudomonas aeruginosa Biofilms on Silicone Implants In Vivo
GENNIP, Maria Van, DAHL CHRISTENSEN, Louise, ALHEDE, Morten, QVORTRUP, Klaus, ØSTRUP JENSEN, Peter, HØIBY, Niels, GIVSKOV, Michael, BJARNSHOLT, Thomas
Published in Infection and Immunity (01.08.2012)
Published in Infection and Immunity (01.08.2012)
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Journal Article
Ajoene, a Sulfur-Rich Molecule from Garlic, Inhibits Genes Controlled by Quorum Sensing
Jakobsen, Tim Holm, van Gennip, Maria, Phipps, Richard Kerry, Shanmugham, Meenakshi Sundaram, Christensen, Louise Dahl, Alhede, Morten, Skindersoe, Mette Eline, Rasmussen, Thomas Bovbjerg, Friedrich, Karlheinz, Uthe, Friedrich, Jensen, Peter Østrup, Moser, Claus, Nielsen, Kristian Fog, Eberl, Leo, Larsen, Thomas Ostenfeld, Tanner, David, Høiby, Niels, Bjarnsholt, Thomas, Givskov, Michael
Published in Antimicrobial Agents and Chemotherapy (01.05.2012)
Published in Antimicrobial Agents and Chemotherapy (01.05.2012)
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Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm
Alhede, Morten, Kragh, Kasper Nørskov, Qvortrup, Klaus, Allesen-Holm, Marie, van Gennip, Maria, Christensen, Louise D, Jensen, Peter Østrup, Nielsen, Anne K, Parsek, Matt, Wozniak, Dan, Molin, Søren, Tolker-Nielsen, Tim, Høiby, Niels, Givskov, Michael, Bjarnsholt, Thomas
Published in PloS one (21.11.2011)
Published in PloS one (21.11.2011)
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Efficacy of a synthetic antimicrobial peptidomimetic versus vancomycin in a Staphylococcus epidermidis device-related murine peritonitis model
Cavanagh, Jorunn Pauline, Granslo, Hildegunn Norbakken, Fredheim, Elizabeth Aarag, Christophersen, Lars, Jensen, Peter Østrup, Thomsen, Kim, Van Gennip, Maria, Klingenberg, Claus, Flaegstad, Trond, Moser, Claus
Published in Journal of antimicrobial chemotherapy (01.09.2013)
Published in Journal of antimicrobial chemotherapy (01.09.2013)
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Synergistic antibacterial efficacy of early combination treatment with tobramycin and quorum-sensing inhibitors against Pseudomonas aeruginosa in an intraperitoneal foreign-body infection mouse model
CHRISTENSEN, Louise D, VAN GENNIP, Maria, JAKOBSEN, Tim H, ALHEDE, Morten, PETTER HOUGEN, Hans, HØIBY, Niels, BJARNSHOLT, Thomas, GIVSKOV, Michael
Published in Journal of antimicrobial chemotherapy (01.05.2012)
Published in Journal of antimicrobial chemotherapy (01.05.2012)
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Journal Article
Inactivation of the rhlA gene in Pseudomonas aeruginosa prevents rhamnolipid production, disabling the protection against polymorphonuclear leukocytes
VAN GENNIP, MARIA, CHRISTENSEN, LOUISE DAHL, ALHEDE, MORTEN, PHIPPS, RICHARD, JENSEN, PETER ØSTRUP, CHRISTOPHERSEN, LARS, PAMP, SÜNJE JOHANNA, MOSER, CLAUS, MIKKELSEN, PER JENSEN, KOH, ANDREW Y, TOLKER-NIELSEN, TIM, PIER, GERALD B, HØIBY, NIELS, GIVSKOV, MICHAEL, BJARNSHOLT, THOMAS
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.07.2009)
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.07.2009)
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Journal Article
Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes
Alhede, Morten, Bjarnsholt, Thomas, Jensen, Peter O, Phipps, Richard Kerry, Moser, Claus, Christophersen, Lars, Christensen, Louise Dahl, van Gennip, Maria, Parsek, Matt, Hoiby, Niels, Rasmussen, Thomas Bovbjerg, Givskov, Michael
Published in Microbiology (Society for General Microbiology) (01.11.2009)
Published in Microbiology (Society for General Microbiology) (01.11.2009)
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Novel experimental Pseudomonas aeruginosa lung infection model mimicking long-term host-pathogen interactions in cystic fibrosis
MOSER, CLAUS, VAN GENNIP, MARIA, BJARNSHOLT, THOMAS, JENSEN, PETER ØSTRUP, LEE, BAOLERI, HOUGEN, HANS PETTER, CALUM, HENRIK, CIOFU, OANA, GIVSKOV, MICHAEL, MOLIN, SØREN, HØIBY, NIELS
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.02.2009)
Published in APMIS : acta pathologica, microbiologica et immunologica Scandinavica (01.02.2009)
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Augmented effect of early antibiotic treatment in mice with experimental lung infections due to sequentially adapted mucoid strains of Pseudomonas aeruginosa
van Gennip, Maria, Moser, Claus, Christensen, Louise D., Bjarnsholt, Thomas, Calum, Henrik, Jensen, Peter Ø., Christophersen, Lars, Hougen, Hans Petter, Ciofu, Oana, Molin, Søren, Givskov, Michael, Høiby, Niels
Published in Journal of antimicrobial chemotherapy (01.12.2009)
Published in Journal of antimicrobial chemotherapy (01.12.2009)
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Journal Article
AJOENE FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
Shanmugham, Meenakshi Sundaram, Tanner, David, Bjarnsholt, Thomas, Phipps, Richard, Jakobsen, Tim Holm, Givskov, Michael, Høiby, Niels, van Gennip, Maria, Christensen, Louise Dahl, Jensen, Peter Østrup, Larsen, Thomas Ostenfeld
Year of Publication 17.04.2019
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Year of Publication 17.04.2019
Patent
PROCESS FOR THE MANUFACTURE OF AJOENE DERIVATIVES
Shanmugham, Meenakshi Sundaram, Tanner, David, Bjarnsholt, Thomas, Jensen, Peter Ostrup, Phipps, Richard, Gennip, Maria Van, Jakobsen, Tim Holm, Givskov, Michael, Hoiby, Niels, Christensen, Louise Dahl, Larsen, Thomas Ostenfeld
Year of Publication 01.06.2017
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Year of Publication 01.06.2017
Patent
PROCESS FOR THE MANUFACTURE OF AJOENE DERIVATIVES
BJARNSHOLT, THOMAS, JENSEN, PETER ØSTRUP, GIVSKOV, MICHAEL, LARSEN, THOMAS OSTENFELD, HØIBY, NIELS, TANNER, DAVID, JAKOBSEN, TIM HOLM, CHRISTENSEN, LOUISE DAHL, PHIPPS, RICHARD, SHANMUGHAM, MEENAKSHI SUNDARAM, VAN GENNIP, MARIA
Year of Publication 17.08.2016
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Year of Publication 17.08.2016
Patent
PROCESS FOR THE MANUFACTURE OF AJOENE DERIVATIVES
BJARNSHOLT, THOMAS, GIVSKOV, MICHAEL, LARSEN, THOMAS OSTENFELD, TANNER, DAVID, JAKOBSEN, TIM HOLM, CHRISTENSEN, LOUISE DAHL, JENSEN, PETER OSTRUP, PHIPPS, RICHARD, SHANMUGHAM, MEENAKSHI SUNDARAM, HOIBY, NIELS, GENNIP, MARIA VAN
Year of Publication 16.06.2016
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Year of Publication 16.06.2016
Patent
AJOENE FOR USE IN THE TREATMENT OF BACTERIAL INFECTIONS
BJARNSHOLT, THOMAS, JENSEN, PETER ØSTRUP, GIVSKOV, MICHAEL, LARSEN, THOMAS OSTENFELD, HØIBY, NIELS, TANNER, DAVID, JAKOBSEN, TIM HOLM, CHRISTENSEN, LOUISE DAHL, PHIPPS, RICHARD, SHANMUGHAM, MEENAKSHI SUNDARAM, VAN GENNIP, MARIA
Year of Publication 18.05.2016
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Year of Publication 18.05.2016
Patent