Genetic and functional diversity of propagating cells in glioblastoma
Piccirillo, Sara G M, Colman, Sue, Potter, Nicola E, van Delft, Frederik W, Lillis, Suzanne, Carnicer, Maria-Jose, Kearney, Lyndal, Watts, Colin, Greaves, Mel
Published in Stem cell reports (13.01.2015)
Published in Stem cell reports (13.01.2015)
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RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia
Papaemmanuil, Elli, Rapado, Inmaculada, Li, Yilong, Potter, Nicola E, Wedge, David C, Tubio, Jose, Alexandrov, Ludmil B, Van Loo, Peter, Cooke, Susanna L, Marshall, John, Martincorena, Inigo, Hinton, Jonathan, Gundem, Gunes, van Delft, Frederik W, Nik-Zainal, Serena, Jones, David R, Ramakrishna, Manasa, Titley, Ian, Stebbings, Lucy, Leroy, Catherine, Menzies, Andrew, Gamble, John, Robinson, Ben, Mudie, Laura, Raine, Keiran, O'Meara, Sarah, Teague, Jon W, Butler, Adam P, Cazzaniga, Giovanni, Biondi, Andrea, Zuna, Jan, Kempski, Helena, Muschen, Markus, Ford, Anthony M, Stratton, Michael R, Greaves, Mel, Campbell, Peter J
Published in Nature genetics (01.02.2014)
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Phase II-like murine trial identifies synergy between dexamethasone and dasatinib in T-cell acute lymphoblastic leukemia
Shi, Yuzhe, Beckett, Melanie C, Blair, Helen J, Tirtakusuma, Ricky, Nakjang, Sirintra, Enshaei, Amir, Halsey, Christina, Vormoor, Josef, Heidenreich, Olaf, Krippner-Heidenreich, Anja, van Delft, Frederik W
Published in Haematologica (Roma) (01.04.2021)
Published in Haematologica (Roma) (01.04.2021)
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Hyperactive CREB subpopulations increase during therapy in pediatric B-lineage acute lymphoblastic leukemia
Masic, Dino, Fee, Kayleigh, Bell, Hayden, Case, Marian, Witherington, Gabby, Lansbury, Sophie, Ojeda-Garcia, Juan, McDonald, David, Schwab, Claire, Van Delft, Frederik W, Filby, Andrew, Irving, Julie Anne Elizabeth
Published in Haematologica (Roma) (01.04.2023)
Published in Haematologica (Roma) (01.04.2023)
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Targeting hyperactive platelet-derived growth factor receptor-β signaling in T-cell acute lymphoblastic leukemia and lymphoma
De Coninck, Stien, De Smedt, Renate, Lintermans, Beatrice, Reunes, Lindy, Kosasih, Hansen J, Reekmans, Alexandra, Brown, Lauren M, Van Roy, Nadine, Palhais, Bruno, Roels, Juliette, Van der Linden, Malaika, Van Dorpe, Jo, Ntziachristos, Panagiotis, Van Delft, Frederik W, Mansour, Marc R, Pieters, Tim, Lammens, Tim, De Moerloose, Barbara, De Bock, Charles E, Goossens, Steven, Van Vlierberghe, Pieter
Published in Haematologica (Roma) (01.05.2024)
Published in Haematologica (Roma) (01.05.2024)
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Molecular characterization and clinical outcome of B-cell precursor acute lymphoblastic leukemia with IG-MYC rearrangement
Bomken, Simon, Enshaei, Amir, Schwalbe, Edward C, Mikulasova, Aneta, Dai, Yunfeng, Zaka, Masood, Fung, Kent T M, Bashton, Matthew, Lim, Huezin, Jones, Lisa, Karataraki, Nefeli, Winterman, Emily, Ashby, Cody, Attarbaschi, Andishe, Bertrand, Yves, Bradtke, Jutta, Buldini, Barbara, Burke, G A Amos, Cazzaniga, Giovanni, Gohring, Gudrun, De Groot-Kruseman, Hesta A, Haferlach, Claudia, Nigro, Luca Lo, Parihar, Mayur, Plesa, Adriana, Seaford, Emma, Sonneveld, Edwin, Strehl, Sabine, Van der Velden, Vincent H J, Rand, Vikki, Hunger, Stephen P, Harrison, Christine J, Bacon, Chris M, Van Delft, Frederik W, Loh, Mignon L, Moppett, John, Vormoor, Josef, Walker, Brian A, Moorman, Anthony V, Russell, Lisa J
Published in Haematologica (Roma) (01.03.2023)
Published in Haematologica (Roma) (01.03.2023)
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Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia
van Delft, Frederik W., Horsley, Sharon, Colman, Sue, Anderson, Kristina, Bateman, Caroline, Kempski, Helena, Zuna, Jan, Eckert, Cornelia, Saha, Vaskar, Kearney, Lyndal, Ford, Anthony, Greaves, Mel
Published in Blood (09.06.2011)
Published in Blood (09.06.2011)
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Targeting WEE1 kinase as a p53-independent therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
Bell, Hayden L., Blair, Helen J., Singh, Mankaran, Moorman, Anthony V., Heidenreich, Olaf, van Delft, Frederik W., Lunec, John, Irving, Julie A. E.
Published in Cancer cell international (15.09.2023)
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Modeling the evolution of ETV6-RUNX1–induced B-cell precursor acute lymphoblastic leukemia in mice
van der Weyden, Louise, Giotopoulos, George, Rust, Alistair G., Matheson, Louise S., van Delft, Frederik W., Kong, Jun, Corcoran, Anne E., Greaves, Mel F., Mullighan, Charles G., Huntly, Brian J., Adams, David J.
Published in Blood (28.07.2011)
Published in Blood (28.07.2011)
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Complex Genomic Alterations and Gene Expression in Acute Lymphoblastic Leukemia with Intrachromosomal Amplification of Chromosome 21
Strefford, Jon C., van Delft, Frederik W., Robinson, Hazel M., Worley, Helen, Yiannikouris, Olga, Selzer, Rebecca, Richmond, Todd, Hann, Ian, Bellotti, Tony, Raghavan, Manoj, Young, Bryan D., Saha, Vaskar, Harrison, Christine J.
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2006)
Published in Proceedings of the National Academy of Sciences - PNAS (23.05.2006)
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Immunologically silent cancer clone transmission from mother to offspring
Isoda, Takeshi, Ford, Anthony M, Tomizawa, Daisuke, van Delft, Frederik W, De Castro, David Gonzalez, Mitsuiki, Norkio, Score, Joannah, Taki, Tomohiko, Morio, Tomohiro, Takagi, Masatoshi, Saji, Hiroh, Greaves, Mel, Mizutani, Shuki
Published in Proceedings of the National Academy of Sciences - PNAS (20.10.2009)
Published in Proceedings of the National Academy of Sciences - PNAS (20.10.2009)
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Genetic variegation of clonal architecture and propagating cells in leukaemia
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Published in Nature (London) (20.01.2011)
Published in Nature (London) (20.01.2011)
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Disease evolution and outcomes in familial AML with germline CEBPA mutations
Tawana, Kiran, Wang, Jun, Renneville, Aline, Bödör, Csaba, Hills, Robert, Loveday, Chey, Savic, Aleksandar, Van Delft, Frederik W., Treleaven, Jennifer, Georgiades, Panayiotis, Uglow, Elizabeth, Asou, Norio, Uike, Naokuni, Debeljak, Maruša, Jazbec, Janez, Ancliff, Philip, Gale, Rosemary, Thomas, Xavier, Mialou, Valerie, Döhner, Konstanze, Bullinger, Lars, Mueller, Beatrice, Pabst, Thomas, Stelljes, Matthias, Schlegelberger, Brigitte, Wozniak, Eva, Iqbal, Sameena, Okosun, Jessica, Araf, Shamzah, Frank, Anne-Katrine, Lauridsen, Felicia B., Porse, Bo, Nerlov, Claus, Owen, Carolyn, Dokal, Inderjeet, Gribben, John, Smith, Matthew, Preudhomme, Claude, Chelala, Claude, Cavenagh, Jamie, Fitzgibbon, Jude
Published in Blood (03.09.2015)
Published in Blood (03.09.2015)
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Combination p53 activation and BCL-xL/BCL-2 inhibition as a therapeutic strategy in high-risk and relapsed acute lymphoblastic leukemia
Bell, Hayden L., Blair, Helen J., Jepson Gosling, Samantha J., Galler, Martin, Astley, Daniel, Moorman, Anthony V., Heidenreich, Olaf, Veal, Gareth J., van Delft, Frederik W., Lunec, John, Irving, Julie A. E.
Published in Leukemia (01.06.2024)
Published in Leukemia (01.06.2024)
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Unusual relapse of low hypodiploid acute lymphoblastic leukaemia in a family with Li‐Fraumeni syndrome
Delft, Frederik W., Bailey, Simon, Skinner, Roderick, Shenton, Geoff, Carey, Peter, Campbell‐Hewson, Quentin, Hale, Juliet, McDonald, Leigh, Pearce, Kate, Martin, Richard, Robinson, Katrina, Cuthbert, Gavin
Published in Pediatric blood & cancer (01.09.2023)
Published in Pediatric blood & cancer (01.09.2023)
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Adjuvant tyrosine kinase inhibitor therapy improves outcome for children and adolescents with acute lymphoblastic leukaemia who have an ABL‐class fusion
Moorman, Anthony V., Schwab, Claire, Winterman, Emily, Hancock, Jerry, Castleton, Anna, Cummins, Michelle, Gibson, Brenda, Goulden, Nick, Kearns, Pam, James, Beki, Kirkwood, Amy A., Lancaster, Donna, Madi, Mabrouk, McMillan, Andrew, Motwani, Jayashree, Norton, Alice, O’Marcaigh, Aengus, Patrick, Katharine, Bhatnagar, Neha, Qureshi, Amrana, Richardson, Deborah, Stokley, Simone, Taylor, Gordon, Delft, Frederik W., Moppett, John, Harrison, Christine J., Samarasinghe, Sujith, Vora, Ajay
Published in British journal of haematology (01.12.2020)
Published in British journal of haematology (01.12.2020)
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RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia
Matthijssens, Filip, Sharma, Nitesh D, Nysus, Monique, Nickl, Christian K, Kang, Huining, Perez, Dominique R, Lintermans, Beatrice, Van Loocke, Wouter, Roels, Juliette, Peirs, Sofie, Demoen, Lisa, Pieters, Tim, Reunes, Lindy, Lammens, Tim, De Moerloose, Barbara, Van Nieuwerburgh, Filip, Deforce, Dieter L, Cheung, Laurence C, Kotecha, Rishi S, Risseeuw, Martijn Dp, Van Calenbergh, Serge, Takarada, Takeshi, Yoneda, Yukio, van Delft, Frederik W, Lock, Richard B, Merkley, Seth D, Chigaev, Alexandre, Sklar, Larry A, Mullighan, Charles G, Loh, Mignon L, Winter, Stuart S, Hunger, Stephen P, Goossens, Steven, Castillo, Eliseo F, Ornatowski, Wojciech, Van Vlierberghe, Pieter, Matlawska-Wasowska, Ksenia
Published in The Journal of clinical investigation (15.03.2021)
Published in The Journal of clinical investigation (15.03.2021)
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The subclonal complexity of STIL-TAL1+ T-cell acute lymphoblastic leukaemia
Furness, Caroline L, Mansur, Marcela B, Weston, Victoria J, Ermini, Luca, van Delft, Frederik W, Jenkinson, Sarah, Gale, Rosemary, Harrison, Christine J, Pombo-de-Oliveira, Maria S, Sanchez-Martin, Marta, Ferrando, Adolfo A, Kearns, Pamela, Titley, Ian, Ford, Anthony M, Potter, Nicola E, Greaves, Mel
Published in Leukemia (01.09.2018)
Published in Leukemia (01.09.2018)
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