Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1
Chen, Guo-Yun, Brown, Nicholas K, Wu, Wei, Khedri, Zahra, Yu, Hai, Chen, Xi, van de Vlekkert, Diantha, D'Azzo, Alessandra, Zheng, Pan, Liu, Yang
Published in eLife (03.09.2014)
Published in eLife (03.09.2014)
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Journal Article
MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat
Annunziata, Ida, van de Vlekkert, Diantha, Wolf, Elmar, Finkelstein, David, Neale, Geoffrey, Machado, Eda, Mosca, Rosario, Campos, Yvan, Tillman, Heather, Roussel, Martine F., Andrew Weesner, Jason, Ellen Fremuth, Leigh, Qiu, Xiaohui, Han, Min-Joon, Grosveld, Gerard C., d’Azzo, Alessandra
Published in Nature communications (09.08.2019)
Published in Nature communications (09.08.2019)
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Journal Article
Lysosomes and Cancer Progression: A Malignant Liaison
Machado, Eda R, Annunziata, Ida, van de Vlekkert, Diantha, Grosveld, Gerard C, d'Azzo, Alessandra
Published in Frontiers in cell and developmental biology (26.02.2021)
Published in Frontiers in cell and developmental biology (26.02.2021)
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Journal Article
Altered GM1 catabolism affects NMDAR-mediated Ca2+ signaling at ER-PM junctions and increases synaptic spine formation in a GM1-gangliosidosis model
Weesner, Jason A., Annunziata, Ida, van de Vlekkert, Diantha, Robinson, Camenzind G., Campos, Yvan, Mishra, Ashutosh, Fremuth, Leigh E., Gomero, Elida, Hu, Huimin, d’Azzo, Alessandra
Published in Cell reports (Cambridge) (28.05.2024)
Published in Cell reports (Cambridge) (28.05.2024)
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Journal Article
Regulated lysosomal exocytosis mediates cancer progression
Machado, Eda, White-Gilbertson, Shai, van de Vlekkert, Diantha, Janke, Laura, Moshiach, Simon, Campos, Yvan, Finkelstein, David, Gomero, Elida, Mosca, Rosario, Qiu, Xiaohui, Morton, Christopher L, Annunziata, Ida, d'Azzo, Alessandra
Published in Science advances (01.12.2015)
Published in Science advances (01.12.2015)
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Journal Article
Excessive exosome release is the pathogenic pathway linking a lysosomal deficiency to generalized fibrosis
van de Vlekkert, Diantha, Demmers, Jeroen, Nguyen, Xinh-Xinh, Campos, Yvan, Machado, Eda, Annunziata, Ida, Hu, Huimin, Gomero, Elida, Qiu, Xiaohui, Bongiovanni, Antonella, Feghali-Bostwick, Carol A, d'Azzo, Alessandra
Published in Science advances (01.07.2019)
Published in Science advances (01.07.2019)
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Journal Article
AAV-mediated gene therapy for galactosialidosis: A long-term safety and efficacy study
Hu, Huimin, Mosca, Rosario, Gomero, Elida, van de Vlekkert, Diantha, Campos, Yvan, Fremuth, Leigh E., Brown, Scott A., Weesner, Jason A., Annunziata, Ida, d’Azzo, Alessandra
Published in Molecular therapy. Methods & clinical development (10.12.2021)
Published in Molecular therapy. Methods & clinical development (10.12.2021)
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Journal Article
Galactosialidosis: preclinical enzyme replacement therapy in a mouse model of the disease, a proof of concept
Cadaoas, Jaclyn, Hu, Huimin, Boyle, Gabrielle, Gomero, Elida, Mosca, Rosario, Jayashankar, Kartika, Machado, Mike, Cullen, Sean, Guzman, Belle, van de Vlekkert, Diantha, Annunziata, Ida, Vellard, Michel, Kakkis, Emil, Koppaka, Vish, d’Azzo, Alessandra
Published in Molecular therapy. Methods & clinical development (12.03.2021)
Published in Molecular therapy. Methods & clinical development (12.03.2021)
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Journal Article
LPS-induced cytokine production in human dendritic cells is regulated by sialidase activity
Stamatos, Nicholas M., Carubelli, Ivan, Vlekkert, Diantha, Bonten, Erik J., Papini, Nadia, Feng, Chiguang, Venerando, Bruno, dˈAzzo, Alessandra, Cross, Alan S., Wang, Lai‐Xi, Gomatos, Peter J.
Published in Journal of leukocyte biology (01.12.2010)
Published in Journal of leukocyte biology (01.12.2010)
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Journal Article
Preclinical Enzyme Replacement Therapy with a Recombinant β-Galactosidase-Lectin Fusion for CNS Delivery and Treatment of GM1-Gangliosidosis
Weesner, Jason Andrew, Annunziata, Ida, Yang, Tianhong, Acosta, Walter, Gomero, Elida, Hu, Huimin, van de Vlekkert, Diantha, Ayala, Jorge, Qiu, Xiaohui, Fremuth, Leigh Ellen, Radin, David N, Cramer, Carole L, d'Azzo, Alessandra
Published in Cells (Basel, Switzerland) (01.08.2022)
Published in Cells (Basel, Switzerland) (01.08.2022)
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Journal Article
Isolation, Purification and Characterization of Exosomes from Fibroblast Cultures of Skeletal Muscle
van de Vlekkert, Diantha, Qiu, Xiaohui, Annunziata, Ida, d'Azzo, Alessandra
Published in Bio-protocol (05.04.2020)
Published in Bio-protocol (05.04.2020)
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Journal Article
Conventional and Unconventional Therapeutic Strategies for Sialidosis Type I
Mosca, Rosario, van de Vlekkert, Diantha, Campos, Yvan, Fremuth, Leigh E, Cadaoas, Jaclyn, Koppaka, Vish, Kakkis, Emil, Tifft, Cynthia, Toro, Camilo, Allievi, Simona, Gellera, Cinzia, Canafoglia, Laura, Visser, Gepke, Annunziata, Ida, d'Azzo, Alessandra
Published in Journal of clinical medicine (04.03.2020)
Published in Journal of clinical medicine (04.03.2020)
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Journal Article
Muscle degeneration in neuraminidase 1-deficient mice results from infiltration of the muscle fibers by expanded connective tissue
Zanoteli, Edmar, de Vlekkert, Diantha van, Bonten, Erik J., Hu, Huimin, Mann, Linda, Gomero, Elida M., Harris, A. John, Ghersi, Giulio, d'Azzo, Alessandra
Published in Biochimica et biophysica acta (01.07.2010)
Published in Biochimica et biophysica acta (01.07.2010)
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Journal Article
Haploinsufficiency of the lysosomal sialidase NEU1 results in a model of pleomorphic rhabdomyosarcoma in mice
Machado, Eda R., van de Vlekkert, Diantha, Sheppard, Heather S., Perry, Scott, Downing, Susanna M., Laxton, Jonathan, Ashmun, Richard, Finkelstein, David B., Neale, Geoffrey A., Hu, Huimin, Harwood, Frank C., Koo, Selene C., Grosveld, Gerard C., d’Azzo, Alessandra
Published in Communications biology (20.09.2022)
Published in Communications biology (20.09.2022)
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Journal Article
AAV-mediated gene therapy in a mouse model of sialidosis
van de Vlekkert, Diantha, Hu, Huimin, Weesner, Jason A., Gomero, Elida M., d'Azzo, Alessandra
Published in Molecular genetics and metabolism (01.02.2023)
Published in Molecular genetics and metabolism (01.02.2023)
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Journal Article
AAV-mediated gene therapy for sialidosis
van de Vlekkert, Diantha, Hu, Huimin, Weesner, Jason A., Fremuth, Leigh E., Brown, Scott A., Lu, Meifen, Gomero, Elida, Campos, Yvan, Sheppard, Heather, d’Azzo, Alessandra
Published in Molecular therapy (03.07.2024)
Published in Molecular therapy (03.07.2024)
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Journal Article