Efficient Recombinase-Mediated Cassette Exchange in hPSCs to Study the Hepatocyte Lineage Reveals AAVS1 Locus-Mediated Transgene Inhibition
Ordovás, Laura, Boon, Ruben, Pistoni, Mariaelena, Chen, Yemiao, Wolfs, Esther, Guo, Wenting, Sambathkumar, Rangarajan, Bobis-Wozowicz, Sylwia, Helsen, Nicky, Vanhove, Jolien, Berckmans, Pieter, Cai, Qing, Vanuytsel, Kim, Eggermont, Kristel, Vanslembrouck, Veerle, Schmidt, Béla Z., Raitano, Susanna, Van Den Bosch, Ludo, Nahmias, Yaakov, Cathomen, Toni, Struys, Tom, Verfaillie, Catherine M.
Published in Stem cell reports (10.11.2015)
Published in Stem cell reports (10.11.2015)
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Journal Article
Potential Therapeutic Role of HDAC Inhibitors in FUS-ALS
Tejido, Clara, Pakravan, Donya, Bosch, Ludo Van Den
Published in Frontiers in molecular neuroscience (09.08.2021)
Published in Frontiers in molecular neuroscience (09.08.2021)
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Journal Article
Progranulin functions as a neurotrophic factor to regulate neurite outgrowth and enhance neuronal survival
Van Damme, Philip, Van Hoecke, Annelies, Lambrechts, Diether, Vanacker, Peter, Bogaert, Elke, van Swieten, John, Carmeliet, Peter, Van Den Bosch, Ludo, Robberecht, Wim
Published in The Journal of cell biology (07.04.2008)
Published in The Journal of cell biology (07.04.2008)
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Journal Article
Astrocyte-derived Jagged-1 mitigates deleterious Notch signaling in amyotrophic lateral sclerosis
Nonneman, Annelies, Criem, Nathan, Lewandowski, Sebastian A., Nuyts, Rik, Thal, Dietmar R., Pfrieger, Frank W., Ravits, John, Van Damme, Philip, Zwijsen, An, Van Den Bosch, Ludo, Robberecht, Wim
Published in Neurobiology of disease (01.11.2018)
Published in Neurobiology of disease (01.11.2018)
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Journal Article
A generic approach to study the kinetics of liquid–liquid phase separation under near-native conditions
Van Lindt, Joris, Bratek-Skicki, Anna, Nguyen, Phuong N., Pakravan, Donya, Durán-Armenta, Luis F., Tantos, Agnes, Pancsa, Rita, Van Den Bosch, Ludo, Maes, Dominique, Tompa, Peter
Published in Communications biology (19.01.2021)
Published in Communications biology (19.01.2021)
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Journal Article
Antisense, but not sense, repeat expanded RNAs activate PKR/eIF2α-dependent ISR in C9ORF72 FTD/ALS
Parameswaran, Janani, Zhang, Nancy, Braems, Elke, Tilahun, Kedamawit, Pant, Devesh C, Yin, Keena, Asress, Seneshaw, Heeren, Kara, Banerjee, Anwesha, Davis, Emma, Schwartz, Samantha L, Conn, Graeme L, Bassell, Gary J, Van Den Bosch, Ludo, Jiang, Jie
Published in eLife (19.04.2023)
Published in eLife (19.04.2023)
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Journal Article
Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity
Van Damme, Philip, Bogaert, Elke, Dewil, Maarten, Hersmus, Nicole, Kiraly, Dora, Scheveneels, Wendy, Bockx, Ilse, Braeken, Dries, Verpoorten, Nathalie, Verhoeven, Kristien, Timmerman, Vincent, Herijgers, Paul, Callewaert, Geert, Carmeliet, Peter, Van Den Bosch, Ludo, Robberecht, Wim
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2007)
Published in Proceedings of the National Academy of Sciences - PNAS (11.09.2007)
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Journal Article
Generation of Human Induced Pluripotent Stem Cell (hiPSC)-Derived Astrocytes for Amyotrophic Lateral Sclerosis and Other Neurodegenerative Disease Studies
Dittlau, Katarina Stoklund, Chandrasekaran, Abinaya, Freude, Kristine, Van Den Bosch, Ludo
Published in Bio-protocol (20.02.2024)
Published in Bio-protocol (20.02.2024)
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Journal Article
Triad of TDP43 control in neurodegeneration: autoregulation, localization and aggregation
Tziortzouda, Paraskevi, Van Den Bosch, Ludo, Hirth, Frank
Published in Nature reviews. Neuroscience (01.04.2021)
Published in Nature reviews. Neuroscience (01.04.2021)
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Journal Article
Energy metabolism in ALS: an underappreciated opportunity?
Vandoorne, Tijs, De Bock, Katrien, Van Den Bosch, Ludo
Published in Acta neuropathologica (01.04.2018)
Published in Acta neuropathologica (01.04.2018)
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Journal Article
Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration
Oosthuyse, Bert, Brusselmans, Koen, Collen, Désiré, Storkebaum, Erik, Moons, Lieve, Hicklin, Daniel J, Fujisawa, Hajime, Drost, Maarten R, Sciot, Raf, Vleminckx, Vicky, Hellings, Peter, Vermylen, Patrick, Acker, Till, Laudenbach, Vincent, Dorpe, Jo Van, Gorselink, Marchel, Gressens, Pierre, Lupu, Florea, Raat, Harold, Plate, Karl H, Theilmeier, Gregor, Nuyens, Dieter, Cashman, Neil, Dewerchin, Mieke, Heymans, Stéphane, Robberecht, Wim, Carmeliet, Peter, Bosch, Ludo Van Den, Bruyninckx, Frans, Ince, Can, Beck, Heike, Herbert, Jean-Marc
Published in Nature genetics (01.06.2001)
Published in Nature genetics (01.06.2001)
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Journal Article
Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia
Raitano, Susanna, Ordovàs, Laura, De Muynck, Louis, Guo, Wenting, Espuny-Camacho, Ira, Geraerts, Martine, Khurana, Satish, Vanuytsel, Kim, Tóth, Balazs I, Voets, Thomas, Vandenberghe, Rik, Cathomen, Toni, Van Den Bosch, Ludo, Vanderhaeghen, Pierre, Van Damme, Philip, Verfaillie, Catherine M
Published in Stem cell reports (13.01.2015)
Published in Stem cell reports (13.01.2015)
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Journal Article
Protein Phase Separation: A New Phase in Cell Biology
Boeynaems, Steven, Alberti, Simon, Fawzi, Nicolas L., Mittag, Tanja, Polymenidou, Magdalini, Rousseau, Frederic, Schymkowitz, Joost, Shorter, James, Wolozin, Benjamin, Van Den Bosch, Ludo, Tompa, Peter, Fuxreiter, Monika
Published in Trends in cell biology (01.06.2018)
Published in Trends in cell biology (01.06.2018)
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Journal Article
Spontaneous driving forces give rise to protein−RNA condensates with coexisting phases and complex material properties
Boeynaems, Steven, Holehouse, Alex S., Weinhardt, Venera, Kovacs, Denes, Van Lindt, Joris, Larabell, Carolyn, Van Den Bosch, Ludo, Das, Rhiju, Tompa, Peter S., Pappu, Rohit V., Gitler, Aaron D.
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
Published in Proceedings of the National Academy of Sciences - PNAS (16.04.2019)
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Journal Article
Modelling amyotrophic lateral sclerosis: progress and possibilities
Van Damme, Philip, Robberecht, Wim, Van Den Bosch, Ludo
Published in Disease models & mechanisms (01.05.2017)
Published in Disease models & mechanisms (01.05.2017)
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Journal Article
Proteostasis plays an important role in demyelinating Charcot Marie Tooth disease
Libberecht, Karen, Vangansewinkel, Tim, Van Den Bosch, Ludo, Lambrichts, Ivo, Wolfs, Esther
Published in Biochemical pharmacology (01.10.2023)
Published in Biochemical pharmacology (01.10.2023)
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Journal Article
Author Correction: A generic approach to study the kinetics of liquid–liquid phase separation under near-native conditions
Van Lindt, Joris, Bratek-Skicki, Anna, Nguyen, Phuong N., Pakravan, Donya, Durán-Armenta, Luis F., Tantos, Agnes, Pancsa, Rita, Van Den Bosch, Ludo, Maes, Dominique, Tompa, Peter
Published in Communications biology (02.03.2021)
Published in Communications biology (02.03.2021)
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Journal Article