Medium branched chain fatty acids improve the profile of tricarboxylic acid cycle intermediates in mitochondrial fatty acid β‐oxidation deficient cells: A comparative study
Karunanidhi, Anuradha, Van't Land, Clinton, Rajasundaram, Dhivyaa, Grings, Mateus, Vockley, Jerry, Mohsen, Al‐Walid
Published in Journal of inherited metabolic disease (01.05.2022)
Published in Journal of inherited metabolic disease (01.05.2022)
Get full text
Journal Article
Treatment of VLCAD-Deficient Patient Fibroblasts with Peroxisome Proliferator-Activated Receptor δ Agonist Improves Cellular Bioenergetics
D'Annibale, Olivia M, Phua, Yu Leng, Van't Land, Clinton, Karunanidhi, Anuradha, Dorenbaum, Alejandro, Mohsen, Al-Walid, Vockley, Jerry
Published in Cells (Basel, Switzerland) (24.08.2022)
Published in Cells (Basel, Switzerland) (24.08.2022)
Get full text
Journal Article
Premature aging and reduced cancer incidence associated with near-complete body-wide Myc inactivation
Wang, Huabo, Lu, Jie, Stevens, Taylor, Roberts, Alexander, Mandel, Jordan, Avula, Raghunandan, Ma, Bingwei, Wu, Yijen, Wang, Jinglin, Land, Clinton Van’t, Finkel, Toren, Vockley, Jerry E., Airik, Merlin, Airik, Rannar, Muzumdar, Radhika, Gong, Zhenwei, Torbenson, Michel S., Prochownik, Edward V.
Published in Cell reports (Cambridge) (29.08.2023)
Published in Cell reports (Cambridge) (29.08.2023)
Get full text
Journal Article
Time of day does not impact spinal serotonin levels in humans
Anand, Sharath Kumar, Lavadi, Raj S., Johnston, Benjamin R., Chalif, Joshua I., Scanlon, James M., Wang, Weiwen, Agarwal, Nitin, Hamilton, David K., Fields, Daryl P., Van't Land, Clinton W.
Published in Synapse (New York, N.Y.) (01.05.2024)
Published in Synapse (New York, N.Y.) (01.05.2024)
Get full text
Journal Article
Synthetic mRNA rescues very long-chain acyl-CoA dehydrogenase deficiency in patient fibroblasts and a murine model
Zhao, Xue-Jun, Mohsen, AI-Walid, Mihalik, Stephanie, Solo, Keaton, Aliu, Ermal, Shi, Huifang, Basu, Shakuntala, Kochersperger, Catherine, Van’t Land, Clinton, Karunanidhi, Anuradha, Coughlan, Kimberly A., Siddiqui, Summar, Rice, Lisa M., Hillier, Shawn, Guadagnin, Eleonora, Giangrande, Paloma H., Martini, Paolo G.V., Vockley, Jerry
Published in Molecular genetics and metabolism (01.01.2023)
Published in Molecular genetics and metabolism (01.01.2023)
Get full text
Journal Article
Mitochondrial bioenergetics and cardiolipin remodeling abnormalities in mitochondrial trifunctional protein deficiency
Vieira Neto, Eduardo, Wang, Meicheng, Szuminsky, Austin J., Ferraro, Lethicia, Koppes, Erik, Wang, Yudong, Van’t Land, Clinton, Mohsen, Al-Walid, Zanatta, Geancarlo, El-Gharbawy, Areeg H., Anthonymuthu, Tamil S., Tyurina, Yulia Y., Tyurin, Vladimir A., Kagan, Valerian, Bayır, Hülya, Vockley, Jerry
Published in JCI insight (10.09.2024)
Published in JCI insight (10.09.2024)
Get full text
Journal Article
Messenger RNA rescues medium-chain acyl-CoA dehydrogenase deficiency in fibroblasts from patients and a murine model
Zhao, Xue-Jun, Mohsen, Al-Walid, Mihalik, Stephanie, Solo, Keaton, Basu, Shakuntala, Aliu, Ermal, Shi, Huifang, Kochersberger, Catherine, Karunanidhi, Anuradha, Van’t Land, Clinton, Coughlan, Kimberly A, Siddiqui, Summar, Rice, Lisa M, Hillier, Shawn, Guadagnin, Eleonora, DeAntonis, Christine, Giangrande, Paloma H, Martini, Paolo G V, Vockley, Jerry
Published in Human molecular genetics (04.07.2023)
Published in Human molecular genetics (04.07.2023)
Get full text
Journal Article
An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
Casillo, Stephanie M., Gatesman, Taylor A., Chilukuri, Akanksha, Varadharajan, Srinidhi, Johnson, Brenden J., David Premkumar, Daniel R., Jane, Esther P., Plute, Tritan J., Koncar, Robert F., Stanton, Ann-Catherine J., Biagi-Junior, Carlos A.O., Barber, Callie S., Halbert, Matthew E., Golbourn, Brian J., Halligan, Katharine, Cruz, Andrea F., Mansi, Neveen M., Cheney, Allison, Mullett, Steven J., Land, Clinton Van’t, Perez, Jennifer L., Myers, Max I., Agrawal, Nishant, Michel, Joshua J., Chang, Yue-Fang, Vaske, Olena M., MichaelRaj, Antony, Lieberman, Frank S., Felker, James, Shiva, Sruti, Bertrand, Kelsey C., Amankulor, Nduka, Hadjipanayis, Costas G., Abdullah, Kalil G., Zinn, Pascal O., Friedlander, Robert M., Abel, Taylor J., Nazarian, Javad, Venneti, Sriram, Filbin, Mariella G., Gelhaus, Stacy L., Mack, Stephen C., Pollack, Ian F., Agnihotri, Sameer
Published in Cell reports (Cambridge) (23.01.2024)
Published in Cell reports (Cambridge) (23.01.2024)
Get full text
Journal Article
EFFECT OF TRIHEPTANOIN AND MEDIUM BRANCHED-CHAIN FATTY ACIDS ON LYSINE SUCCINYLATION IN HUMAN MCAD DEFICIENT FIBROBLAST CELLS AND MURINE KO MODEL
Karunanidhi, Anuradha, Basu, Shakuntala, Zhao, Xuejun, Van't land, Clinton, Vockley, Jerry, Mohsen, Al-Walid
Published in Molecular genetics and metabolism (01.03.2023)
Published in Molecular genetics and metabolism (01.03.2023)
Get full text
Journal Article
ACADVL−/−/ACADL−/− mice demonstrate symptoms of very long chain acyl-CoA dehydrogenase deficiency that are rescued by AAV9 gene therapy
Vockley, Jerry, Zhao, Xue-Jun, Seminotti, Bianca, Basu, Shakuntala, Van't Land, Clinton, Stone, Michele, Mallory, Jason, Prentiss, Pilar, Jaslow, Sarah, Turner, Alex, Wasala, Lakmini, Mohsen, Al-Walid
Published in Molecular genetics and metabolism (01.04.2024)
Published in Molecular genetics and metabolism (01.04.2024)
Get full text
Journal Article
Heptanoic and medium branched-chain fatty acids as anaplerotic treatment for medium chain acyl-CoA dehydrogenase deficiency
Karunanidhi, Anuradha, Basu, Shakuntala, Zhao, Xue-Jun, D'Annibale, Olivia, Van't Land, Clinton, Vockley, Jerry, Mohsen, Al-Walid
Published in Molecular genetics and metabolism (01.11.2023)
Published in Molecular genetics and metabolism (01.11.2023)
Get full text
Journal Article
OP007: Cardiolipin remodeling deregulation and mitochondrial bioenergetics alterations in trifunctional protein (TFP) deficiency
Neto, Eduardo Vieira, Wang, Meicheng, Anthonymuthu, Tamil, Szuminsky, Austin, Land, Clinton Van't, Wang, Yudong, Bayır, Hülya, Vockley, Jerry
Published in Genetics in medicine (01.03.2022)
Published in Genetics in medicine (01.03.2022)
Get full text
Journal Article
Biosynthesis of Phenazine Antibiotics in Streptomyces antibioticus: Stereochemistry of Methyl Transfer from Carbon-2 of Acetate
McDonald, Matthew, Wilkinson, Barrie, Van't Land, Clinton W, Mocek, Ulla, Lee, Sungsook, Floss, Heinz G
Published in Journal of the American Chemical Society (23.06.1999)
Published in Journal of the American Chemical Society (23.06.1999)
Get full text
Journal Article
Body‐Wide Inactivation of the Myc‐Like Mlx Transcription Factor Network Accelerates Aging and Increases the Lifetime Cancer Incidence
Wang, Huabo, Stevens, Taylor, Lu, Jie, Roberts, Alexander, Van't Land, Clinton, Muzumdar, Radhika, Gong, Zhenwei, Vockley, Jerry, Prochownik, Edward V.
Published in Advanced science (08.07.2024)
Published in Advanced science (08.07.2024)
Get full text
Journal Article
Empirical and molecular modeling study of the pyridinium species RHPP+, an abundant and potentially neurotoxic metabolite of haloperidol
Ooms, Frédéric, Delvosal, Sébastien, Wouters, Johan, Durant, François, Dockendolf, Gisella, Van’t Land, Clinton, Glass, Thomas, Castagnoli, Jr, Neal, Van der Schyf, Cornelis J.
Published in Perkin 2 : an international journal of physical organic chemistry (2000)
Published in Perkin 2 : an international journal of physical organic chemistry (2000)
Get full text
Journal Article
The Myc-Like Mlx Network Impacts Aging and Metabolism
Wang, Huabo, Stevens, Taylor, Lu, Jie, Roberts, Alexander, Land, Clinton Van't, Muzumdar, Radhika, Gong, Zhenwei, Vockley, Jerry, Prochownik, Edward V
Published in bioRxiv : the preprint server for biology (27.11.2023)
Get more information
Published in bioRxiv : the preprint server for biology (27.11.2023)
Journal Article
Conformational distribution of the potentially neurotoxic metabolite of haloperidol, HPP +, by NMR spectroscopy, X-ray crystallography and molecular dynamics simulations
Ooms, Frederic, Wouters, Johan, Durant, Francois, Castagnoli, Jr, Neal, Vant Land, Clinton, Dockendolf, Gisella, Glass, Thomas, Van der Schyf, Cornelis J.
Published in Journal of the Chemical Society, Perkin Transactions 2 (1997)
Published in Journal of the Chemical Society, Perkin Transactions 2 (1997)
Get full text
Journal Article
Web Resource