Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma
Fulciniti, Mariateresa, Tassone, Pierfrancesco, Hideshima, Teru, Vallet, Sonia, Nanjappa, Puru, Ettenberg, Seth A., Shen, Zhenxin, Patel, Nipun, Tai, Yu-tzu, Chauhan, Dharminder, Mitsiades, Constantine, Prabhala, Rao, Raje, Noopur, Anderson, Kenneth C., Stover, David R., Munshi, Nikhil C.
Published in Blood (09.07.2009)
Published in Blood (09.07.2009)
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Journal Article
Correction: Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications
Bashari, Muhammad Hasan, Fan, Fengjuan, Vallet, Sonia, Sattler, Martin, Arn, Melissa, Luckner-Minden, Claudia, Schulze-Bergkamen, Henning, Zörnig, Inka, Marme, Frederik, Schneeweiss, Andreas, Cardone, Michael H, Opferman, Joseph T, Jäger, Dirk, Podar, Klaus
Published in Breast cancer research : BCR (02.04.2024)
Published in Breast cancer research : BCR (02.04.2024)
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SNX-2112, a selective Hsp90 inhibitor, potently inhibits tumor cell growth, angiogenesis, and osteoclastogenesis in multiple myeloma and other hematologic tumors by abrogating signaling via Akt and ERK
Okawa, Yutaka, Hideshima, Teru, Steed, Paul, Vallet, Sonia, Hall, Steven, Huang, Ken, Rice, John, Barabasz, Amy, Foley, Brianna, Ikeda, Hiroshi, Raje, Noopur, Kiziltepe, Tanyel, Yasui, Hiroshi, Enatsu, Sotaro, Anderson, Kenneth C.
Published in Blood (22.01.2009)
Published in Blood (22.01.2009)
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Journal Article
Activin A promotes multiple myeloma-induced osteolysis and is a promising target for myeloma bone disease
Vallet, Sonia, Mukherjee, Siddhartha, Vaghela, Nileshwari, Hideshima, Teru, Fulciniti, Mariateresa, Pozzi, Samantha, Santo, Loredana, Cirstea, Diana, Patel, Kishan, Sohani, Aliyah R, Guimaraes, Alex, Xie, Wanling, Chauhan, Dharminder, Schoonmaker, Jesse A, Attar, Eyal, Churchill, Michael, Weller, Edie, Munshi, Nikhil, Seehra, Jasbir S, Weissleder, Ralph, Anderson, Kenneth C, Scadden, David T, Raje, Noopur
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2010)
Published in Proceedings of the National Academy of Sciences - PNAS (16.03.2010)
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Journal Article
The Monoclonal Antibody nBT062 Conjugated to Cytotoxic Maytansinoids Has Selective Cytotoxicity Against CD138-Positive Multiple Myeloma Cells In vitro and In vivo
Ikeda, Hiroshi, Hideshima, Teru, Fulciniti, Mariateresa, Lutz, Robert J, Yasui, Hiroshi, Okawa, Yutaka, Kiziltepe, Tanyel, Vallet, Sonia, Pozzi, Samantha, Santo, Loredana, Perrone, Giulia, Tai, Yu-Tzu, Cirstea, Diana, Raje, Noopur S, Uherek, Christoph, Dälken, Benjamin, Aigner, Silke, Osterroth, Frank, Munshi, Nikhil, Richardson, Paul, Anderson, Kenneth C
Published in Clinical cancer research (15.06.2009)
Published in Clinical cancer research (15.06.2009)
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Journal Article
Effect of cachexia on bone turnover in cancer patients: a case-control study
Zwickl, Hannes, Zwickl-Traxler, Elisabeth, Haushofer, Alexander, Seier, Josef, Podar, Klaus, Weber, Michael, Hackner, Klaus, Jacobi, Nico, Pecherstorfer, Martin, Vallet, Sonia
Published in BMC cancer (28.06.2021)
Published in BMC cancer (28.06.2021)
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Journal Article
Dual inhibition of akt/mammalian target of rapamycin pathway by nanoparticle albumin-bound-rapamycin and perifosine induces antitumor activity in multiple myeloma
Cirstea, Diana, Hideshima, Teru, Rodig, Scott, Santo, Loredana, Pozzi, Samantha, Vallet, Sonia, Ikeda, Hiroshi, Perrone, Giulia, Gorgun, Gullu, Patel, Kishan, Desai, Neil, Sportelli, Peter, Kapoor, Shweta, Vali, Shireen, Mukherjee, Siddhartha, Munshi, Nikhil C, Anderson, Kenneth C, Raje, Noopur
Published in Molecular cancer therapeutics (01.04.2010)
Published in Molecular cancer therapeutics (01.04.2010)
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Journal Article
Dual therapeutic targeting of MYC and JUNB transcriptional programs for enhanced anti-myeloma activity
Lind, Judith, Aksoy, Osman, Prchal-Murphy, Michaela, Fan, Fengjuan, Fulciniti, Mariateresa, Stoiber, Dagmar, Bakiri, Latifa, Wagner, Erwin F., Zwickl-Traxler, Elisabeth, Sattler, Martin, Kollmann, Karoline, Vallet, Sonia, Podar, Klaus
Published in Blood cancer journal (New York) (19.08.2024)
Published in Blood cancer journal (New York) (19.08.2024)
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Journal Article
Myeloma Bone Disease: Update on Pathogenesis and Novel Treatment Strategies
Vallet, Sonia, Filzmoser, Julia-Marie, Pecherstorfer, Martin, Podar, Klaus
Published in Pharmaceutics (24.10.2018)
Published in Pharmaceutics (24.10.2018)
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Journal Article
In vivo and in vitro effects of a novel anti-Dkk1 neutralizing antibody in multiple myeloma
Pozzi, Samantha, Fulciniti, Mariateresa, Yan, Hua, Vallet, Sonia, Eda, Homare, Patel, Kishan, Santo, Loredana, Cirstea, Diana, Hideshima, Teru, Schirtzinge, Linda, Kuhstoss, Stuart, Anderson, Kenneth C, Munshi, Nikhil, Scadden, David, Kronenberg, Henry M, Raje, Noopur
Published in Bone (New York, N.Y.) (01.04.2013)
Published in Bone (New York, N.Y.) (01.04.2013)
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Journal Article
Favorable impact of PD1/PD-L1 antagonists on bone remodeling: an exploratory prospective clinical study and ex vivo validation
Gassner, Tamara, Chittilappilly, Christina, Pirich, Theo, Neuditschko, Benjamin, Hackner, Klaus, Lind, Judith, Aksoy, Osman, Graichen, Uwe, Klee, Sascha, Herzog, Franz, Wiesner, Christoph, Errhalt, Peter, Pecherstorfer, Martin, Podar, Klaus, Vallet, Sonia
Published in Journal for immunotherapy of cancer (03.05.2024)
Published in Journal for immunotherapy of cancer (03.05.2024)
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Journal Article
Mcl-1 confers protection of Her2-positive breast cancer cells to hypoxia: therapeutic implications
Bashari, Muhammad Hasan, Fan, Fengjuan, Vallet, Sonia, Sattler, Martin, Arn, Melissa, Luckner-Minden, Claudia, Schulze-Bergkamen, Henning, Zörnig, Inka, Marme, Frederik, Schneeweiss, Andreas, Cardone, Michael H, Opferman, Joseph T, Jäger, Dirk, Podar, Klaus
Published in Breast cancer research : BCR (26.02.2016)
Published in Breast cancer research : BCR (26.02.2016)
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Journal Article
5-Azacytidine, a DNA methyltransferase inhibitor, induces ATR-mediated DNA double-strand break responses, apoptosis, and synergistic cytotoxicity with doxorubicin and bortezomib against multiple myeloma cells
Kiziltepe, Tanyel, Hideshima, Teru, Catley, Laurence, Raje, Noopur, Yasui, Hiroshi, Shiraishi, Norihiko, Okawa, Yutaka, Ikeda, Hiroshi, Vallet, Sonia, Pozzi, Samantha, Ishitsuka, Kenji, Ocio, Enrique M, Chauhan, Dharminder, Anderson, Kenneth C
Published in Molecular cancer therapeutics (01.06.2007)
Published in Molecular cancer therapeutics (01.06.2007)
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Journal Article
Pre-Osteoblasts Stimulate Migration of Breast Cancer Cells via the HGF/MET Pathway
Vallet, Sonia, Bashari, Muhammad Hasan, Fan, Feng-Juan, Malvestiti, Stefano, Schneeweiss, Andreas, Wuchter, Patrick, Jäger, Dirk, Podar, Klaus
Published in PloS one (02.03.2016)
Published in PloS one (02.03.2016)
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Journal Article
The selective adhesion molecule inhibitor Natalizumab decreases multiple myeloma cell growth in the bone marrow microenvironment: therapeutic implications
Podar, Klaus, Zimmerhackl, Alexander, Fulciniti, Mariateresa, Tonon, Giovanni, Hainz, Ursula, Tai, Yu‐Tzu, Vallet, Sonia, Halama, Niels, Jäger, Dirk, Olson, Dian L., Sattler, Martin, Chauhan, Dharminder, Anderson, Kenneth C.
Published in British journal of haematology (01.11.2011)
Published in British journal of haematology (01.11.2011)
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Journal Article
MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts
Vallet, Sonia, Raje, Noopur, Ishitsuka, Kenji, Hideshima, Teru, Podar, Klaus, Chhetri, Shweta, Pozzi, Samantha, Breitkreutz, Iris, Kiziltepe, Tanyel, Yasui, Hiroshi, Ocio, Enrique M., Shiraishi, Norihiko, Jin, Janice, Okawa, Yutaka, Ikeda, Hiroshi, Mukherjee, Siddhartha, Vaghela, Nileshwari, Cirstea, Diana, Ladetto, Marco, Boccadoro, Mario, Anderson, Kenneth C.
Published in Blood (15.11.2007)
Published in Blood (15.11.2007)
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Journal Article
Neutralizing B-Cell–Activating Factor Antibody Improves Survival and Inhibits Osteoclastogenesis in a Severe Combined Immunodeficient Human Multiple Myeloma Model
NERI, Paola, KUMAR, Shaji, MUNSHI, Nikhil C, HIDESHIMA, Teru, ANDERSON, Kenneth C, RAJE, Noopur, FULCINITI, Maria Teresa, VALLET, Sonia, CHHETRI, Shweta, MUKHERJEE, Sidhartha, YUTZUTAI, CHAUHAN, Dharminder, TASSONE, Pierfrancesco, VENUTA, Salvatore
Published in Clinical cancer research (01.10.2007)
Published in Clinical cancer research (01.10.2007)
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Journal Article
High-Dose Zoledronic Acid Impacts Bone Remodeling with Effects on Osteoblastic Lineage and Bone Mechanical Properties
POZZI, Samantha, VALLET, Sonia, SCHOONMAKER, Jesse, WANLING XIE, HIDESHIMA, Teru, WELLER, Edie, BOUXSEIN, Mary L, MUNSHI, Nikhil C, ANDERSON, Kenneth C, RAJE, Noopur, MUKHERJEE, Siddhartha, CIRSTEA, Diana, VAGHELA, Nileshwari, SANTO, Loredana, ROSEN, Eyal, IKEDA, Hiroshi, OKAWA, Yutaka, KIZILTEPE, Tanyel
Published in Clinical cancer research (15.09.2009)
Published in Clinical cancer research (15.09.2009)
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Journal Article
Clinical, Radiographic, and Biochemical Characterization of Multiple Myeloma Patients with Osteonecrosis of the Jaw
RAJE, Noopur, WOO, Sook-Bin, CONNELL, Brendan, WANLING XIE, TAI, Yu-Tzu, SZOT-BARNES, Agnieszka, MEI TIAN, SCHLOSSMAN, Robert L, WELLER, Edie, MUNSHI, Nikhil C, VAN DEN ABBEELE, Annick D, ANDERSON, Kenneth C, HANDE, Karen, YAP, Jeffrey T, RICHARDSON, Paul G, VALLET, Sonia, TREISTER, Nathaniel, HIDESHIMA, Teru, SHEEHY, Niall, CHHETRI, Shweta
Published in Clinical cancer research (15.04.2008)
Published in Clinical cancer research (15.04.2008)
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Journal Article
JS-K, a GST-activated nitric oxide generator, induces DNA double-strand breaks, activates DNA damage response pathways, and induces apoptosis in vitro and in vivo in human multiple myeloma cells
Kiziltepe, Tanyel, Hideshima, Teru, Ishitsuka, Kenji, Ocio, Enrique M., Raje, Noopur, Catley, Laurence, Li, Chun-Qi, Trudel, Laura J., Yasui, Hiroshi, Vallet, Sonia, Kutok, Jeffery L., Chauhan, Dharminder, Mitsiades, Constantine S., Saavedra, Joseph E., Wogan, Gerald N., Keefer, Larry K., Shami, Paul J., Anderson, Kenneth C.
Published in Blood (15.07.2007)
Published in Blood (15.07.2007)
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