RNF219 attenuates global mRNA decay through inhibition of CCR4-NOT complex-mediated deadenylation
Poetz, Fabian, Corbo, Joshua, Levdansky, Yevgen, Spiegelhalter, Alexander, Lindner, Doris, Magg, Vera, Lebedeva, Svetlana, Schweiggert, Jörg, Schott, Johanna, Valkov, Eugene, Stoecklin, Georg
Published in Nature communications (09.12.2021)
Published in Nature communications (09.12.2021)
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Journal Article
DAP5 enables main ORF translation on mRNAs with structured and uORF-containing 5' leaders
Weber, Ramona, Kleemann, Leon, Hirschberg, Insa, Chung, Min-Yi, Valkov, Eugene, Igreja, Cátia
Published in Nature communications (06.12.2022)
Published in Nature communications (06.12.2022)
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Journal Article
GIGYF1/2 proteins use auxiliary sequences to selectively bind to 4EHP and repress target mRNA expression
Peter, Daniel, Weber, Ramona, Sandmeir, Felix, Wohlbold, Lara, Helms, Sigrun, Bawankar, Praveen, Valkov, Eugene, Igreja, Cátia, Izaurralde, Elisa
Published in Genes & development (01.06.2017)
Published in Genes & development (01.06.2017)
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Journal Article
4EHP and GIGYF1/2 Mediate Translation-Coupled Messenger RNA Decay
Weber, Ramona, Chung, Min-Yi, Keskeny, Csilla, Zinnall, Ulrike, Landthaler, Markus, Valkov, Eugene, Izaurralde, Elisa, Igreja, Cátia
Published in Cell reports (Cambridge) (13.10.2020)
Published in Cell reports (Cambridge) (13.10.2020)
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Journal Article
A molecular mechanism for bacterial susceptibility to zinc
McDevitt, Christopher A, Ogunniyi, Abiodun D, Valkov, Eugene, Lawrence, Michael C, Kobe, Bostjan, McEwan, Alastair G, Paton, James C
Published in PLoS pathogens (01.11.2011)
Published in PLoS pathogens (01.11.2011)
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Journal Article
Structural and functional analysis of a plant resistance protein TIR domain reveals interfaces for self-association, signaling, and autoregulation
Bernoux, Maud, Ve, Thomas, Williams, Simon, Warren, Christopher, Hatters, Danny, Valkov, Eugene, Zhang, Xiaoxiao, Ellis, Jeffrey G, Kobe, Bostjan, Dodds, Peter N
Published in Cell host & microbe (17.03.2011)
Published in Cell host & microbe (17.03.2011)
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Journal Article
Regulation by the RNA-binding protein Unkempt at its effector interface
Shah, Kriti, He, Shiyang, Turner, David J, Corbo, Joshua, Rebbani, Khadija, Dominguez, Daniel, Bateman, Joseph M, Cheloufi, Sihem, Igreja, Cátia, Valkov, Eugene, Murn, Jernej
Published in Nature communications (11.04.2024)
Published in Nature communications (11.04.2024)
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Journal Article
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
Valkov, Eugene, Stamp, Anna, DiMaio, Frank, Baker, David, Verstak, Brett, Roversi, Pietro, Kellie, Stuart, Sweet, Matthew J, Mansell, Ashley, Gay, Nicholas J, Martin, Jennifer L, Kobe, Bostjan
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
Published in Proceedings of the National Academy of Sciences - PNAS (06.09.2011)
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A novel co-crystal structure affords the design of gain-of-function lentiviral integrase mutants in the presence of modified PSIP1/LEDGF/p75
Hare, Stephen, Shun, Ming-Chieh, Gupta, Saumya Shree, Valkov, Eugene, Engelman, Alan, Cherepanov, Peter
Published in PLoS pathogens (01.01.2009)
Published in PLoS pathogens (01.01.2009)
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Journal Article
Attenuating ribosome load improves protein output from mRNA by limiting translation-dependent mRNA decay
Bicknell, Alicia A., Reid, David W., Licata, Marissa C., Jones, Adriana K., Cheng, Yi Min, Li, Mengying, Hsiao, Chiaowen Joyce, Pepin, Christopher S., Metkar, Mihir, Levdansky, Yevgen, Fritz, Brian R., Andrianova, Elizaveta A., Jain, Ruchi, Valkov, Eugene, Köhrer, Caroline, Moore, Melissa J.
Published in Cell reports (Cambridge) (23.04.2024)
Published in Cell reports (Cambridge) (23.04.2024)
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Journal Article
Structural basis for Pan3 binding to Pan2 and its function in mRNA recruitment and deadenylation
Wolf, Jana, Valkov, Eugene, Allen, Mark D, Meineke, Birthe, Gordiyenko, Yuliya, McLaughlin, Stephen H, Olsen, Tayla M, Robinson, Carol V, Bycroft, Mark, Stewart, Murray, Passmore, Lori A
Published in The EMBO journal (17.07.2014)
Published in The EMBO journal (17.07.2014)
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Journal Article
Energetic and structural features of SARS-CoV-2 N-protein co-assemblies with nucleic acids
Zhao, Huaying, Wu, Di, Nguyen, Ai, Li, Yan, Adão, Regina C., Valkov, Eugene, Patterson, George H., Piszczek, Grzegorz, Schuck, Peter
Published in iScience (25.06.2021)
Published in iScience (25.06.2021)
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Journal Article
Structure and assembly of the NOT10:11 module of the CCR4-NOT complex
Levdansky, Yevgen, Raisch, Tobias, Deme, Justin C, Pekovic, Filip, Elmlund, Hans, Lea, Susan M, Valkov, Eugene
Published in Communications biology (17.07.2023)
Published in Communications biology (17.07.2023)
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Journal Article
VPS29 is not an active metallo-phosphatase but is a rigid scaffold required for retromer interaction with accessory proteins
Swarbrick, James D, Shaw, Daniel J, Chhabra, Sandeep, Ghai, Rajesh, Valkov, Eugene, Norwood, Suzanne J, Seaman, Matthew N J, Collins, Brett M
Published in PloS one (24.05.2011)
Published in PloS one (24.05.2011)
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Journal Article
De novo GTP biosynthesis is critical for virulence of the fungal pathogen Cryptococcus neoformans
Morrow, Carl A, Valkov, Eugene, Stamp, Anna, Chow, Eve W L, Lee, I Russel, Wronski, Ania, Williams, Simon J, Hill, Justine M, Djordjevic, Julianne T, Kappler, Ulrike, Kobe, Bostjan, Fraser, James A
Published in PLoS pathogens (01.10.2012)
Published in PLoS pathogens (01.10.2012)
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Journal Article
Structural basis for the assembly and disassembly of mRNA nuclear export complexes
Valkov, Eugene, Dean, Jack C., Jani, Divyang, Kuhlmann, Sonja I., Stewart, Murray
Published in Biochimica et biophysica acta (01.06.2012)
Published in Biochimica et biophysica acta (01.06.2012)
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