Human mesenchymal stem cells as a two-edged sword in hepatic regenerative medicine: engraftment and hepatocyte differentiation versus profibrogenic potential
di Bonzo, L Valfrè, Ferrero, I, Cravanzola, C, Mareschi, K, Rustichell, D, Novo, E, Sanavio, F, Cannito, S, Zamara, E, Bertero, M, Davit, A, Francica, S, Novelli, F, Colombatto, S, Fagioli, F, Parola, M
Published in Gut (01.02.2008)
Published in Gut (01.02.2008)
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Overexpression of Bcl-2 by activated human hepatic stellate cells: resistance to apoptosis as a mechanism of progressive hepatic fibrogenesis in humans
Novo, E, Marra, F, Zamara, E, Valfrè di Bonzo, L, Monitillo, L, Cannito, S, Petrai, I, Mazzocca, A, Bonacchi, A, De Franco, R S M, Colombatto, S, Autelli, R, Pinzani, M, Parola, M
Published in Gut (01.08.2006)
Published in Gut (01.08.2006)
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Dose dependent and divergent effects of superoxide anion on cell death, proliferation, and migration of activated human hepatic stellate cells
Novo, E, Marra, F, Zamara, E, Valfrè di Bonzo, L, Caligiuri, A, Cannito, S, Antonaci, C, Colombatto, S, Pinzani, M, Parola, M
Published in Gut (01.01.2006)
Published in Gut (01.01.2006)
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Journal Article
Calcium-dependent diuretic system in preascitic liver cirrhosis
Sansoè, G, Aragno, M, Tomasinelli, C.E, di Bonzo, L. Valfrè, Wong, F, Parola, M
Published in Journal of hepatology (01.11.2010)
Published in Journal of hepatology (01.11.2010)
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Journal Article
Portal hypotensive action of type-I calcimimetic compounds in rats with CCl4 -induced ascitic liver cirrhosis
Sansoè, G, Aragno, M, Tomasinelli, C, Valfrè di Bonzo, L, Rosina, F, Smedile, A, Wong, F, Rizzetto, M, Parola, M
Published in Digestive and liver disease (01.03.2009)
Published in Digestive and liver disease (01.03.2009)
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Early redox-sensitive activation of JNK isoforms switch on hypoxia-induced migration of human hepatic stellate cells
Novo, E, Valfrè di Bonzo, L, Busletta, C, Cannito, S, Povero, D, Colombatto, S, Marra, F, Pinzani, M, Parola, M
Published in Digestive and liver disease (2008)
Published in Digestive and liver disease (2008)
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Redox-sensitive GSK-3β inhibition and late VEGF release mediate hypoxia-dependent epithelial–mesenchymal transition and increased invasiveness in human HepG2 cells
Cannito, S, Novo, E, Compagnone, A, Valfrè di Bonzo, L, Busletta, C, Zamara, E, Bandino, A, Cravanzola, C, Bravoco, V, Colombatto, S, Parola, M
Published in Digestive and liver disease (01.05.2008)
Published in Digestive and liver disease (01.05.2008)
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Journal Article
Common signalling events regulate migration and chemotaxis of hepatic stellate cells and bone marrow-derived mesenchymal stem cells
Valfrè di Bonzo, L, Novo, E, Cannito, S, Busletta, C, Paternostro, C, Mareschi, K, Colombatto, S, Pinzani, M, Fagioli, F, Parola, M
Published in Digestive and liver disease (2008)
Published in Digestive and liver disease (2008)
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PDGF-BB as mitogenic and chemotactic stimulus for bone marrow-derived human mesenchymal stem cells, putative precursors of profibrogenic myofibroblast-like cells
Valfrè di Bonzo, L, Novo, E, Zamara, E, Cannito, S, Ferrero, I, Rustichelli, D, Colombatto, S, Pinzani, M, Forbes, S.J, Fagioli, F, Parola, M
Published in Digestive and liver disease (2007)
Published in Digestive and liver disease (2007)
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136 REDOX-SENSITIVE GSK-3BETA INHIBITION AND LATE VEGF RELEASE MEDIATE HYPOXIA-DEPENDENT EPITHELIAL—MESENCHYMAL TRANSITION AND INCREASED INVASIVENESS IN HUMAN HEPG2 CELLS
Cannito, S, Novo, E, Compagnone, A, Valfre' di Bonzo, L, Busletta, C, Zamara, E, Bandino, A, Cravanzola, C, Bravoco, V, Colombatto, S, Parola, M
Published in Journal of hepatology (2008)
Published in Journal of hepatology (2008)
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484 INTRACELLULAR REDOX CHANGES AND C-JUN N-TERMINAL KINASE ACTIVATION AS CRUCIAL EVENTS IN CYTOKINE-INDUCED CHEMOTAXIS OF HUMAN ACTIVATED HEPATIC STELLATE CELLS
Novo, E, Valfre' di Bonzo, L, Bertolani, C, Povero, D, Busletta, C, Cannito, S, Zamara, E, Compagnone, A, Colombatto, S, Marra, F, Pinzani, M, Parola, M
Published in Journal of hepatology (2008)
Published in Journal of hepatology (2008)
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[352] EPITHELIAL- MESENCHYMAL TRANSITION IN HUMAN HEPATOCELLULAR CARCINOMA CELLS UNDER HYPOXIA: A BETA-CATENIN AND SNAIL-MEDIATED EVENT FAVOURING MIGRATION AND/OR INVASIVENESS
Cannito, S, Novo, E, Cravanzola, C, Zamara, E, Compagnone, A, Valfre' di Bonzo, L, Bandino, A, Colombatto, S, Parola, M
Published in Journal of hepatology (2007)
Published in Journal of hepatology (2007)
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[343] PDGF-BB IS AN EFFECTIVE MITOGENIC AND CHEMOTACTIC STIMULUS FOR BONE MARROW-DERIVED HUMAN MESENCHYMAL STEM CELLS, PUTATIVE PRECURSORS OF PROFIBROGENIC MYOFIBROBLAST-LIKE CELLS
Valfre' di Bonzo, L, Novo, E, Zamara, E, Cannito, S, Ferrero, I, Rustichelli, D, Colombatto, S, Pinzani, M, Forbes, S.T, Fagioli, F, Parola, M
Published in Journal of hepatology (2007)
Published in Journal of hepatology (2007)
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22 BIOMOLECULAR EXPRESSION OF TARGET RECEPTORS OF CALCIMIMETIC AGENTS IN EXPERIMENTAL LIVER CIRRHOSIS: A NEW STRATEGY TO REDUCE PORTAL PRESSURE
Sansoè, G, Aragno, M, Tomasinelli, C.E, di Bonzo, L. Valfrè, Parola, M, Smedile, A, Rizzetto, M
Published in Digestive and liver disease (2010)
Published in Digestive and liver disease (2010)
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Journal Article
Portal hypotensive action of type-I calcimimetic compounds in rats with CCl 4-induced ascitic liver cirrhosis
Sansoè, G., Aragno, M., Tomasinelli, C., Valfrè di Bonzo, L., Rosina, F., Smedile, A., Wong, F., Rizzetto, M., Parola, M.
Published in Digestive and liver disease (2009)
Published in Digestive and liver disease (2009)
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Journal Article
336 VEGF and angiopoietin-1 as hypoxia-inducible, autocrine and paracrine chemotactic factors for human hepatic stellate cells
Novo, E., Cannito, S., Zamara, E., Valfrè di Bonzo, L., Caligiuri, A., Colombatto, S., Marra, E., Pinzani, M., Parola, M.
Published in Journal of hepatology (01.04.2006)
Published in Journal of hepatology (01.04.2006)
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T.N.41 INTRACELLULAR GENERATION OF REACTIVE OXYGEN SPECIES AS A CRUCIAL REQUIREMENT FOR DIRECTIONAL MIGRATION OF HEPATIC PRO-FIBROGENIC CELLS
Novo, E, Busletta, C, di Bonzo, L. Valfrè, Povero, D, Paternostro, C, Cannito, S, Mareschi, K, Ferrero, I, David, E, Marra, F, Fagioli, F, Pinzani, M, Parola, M
Published in Digestive and liver disease (2010)
Published in Digestive and liver disease (2010)
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Journal Article
345 BcI-2 overexpression in human activated hepatic stellate cells: A survival and pro-fibrogenic mechanism
Cannito, S., Novo, E., Zamara, E., Valfrè di Bonzo, L., DeFranco, R., Mazzocca, A., Colombatto, S., Marra, E., Autelli, R., Pinzani, M., Parola, M.
Published in Journal of hepatology (01.04.2006)
Published in Journal of hepatology (01.04.2006)
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Journal Article
345 BcI-2 overexpression in human activated hepatic stellate cells: A survival and pro-fibrogenic mechanism: 346 Abstract withdrawn
Cannito, S., Novo, E., Zamara, E., Valfrè di Bonzo, L., DeFranco, R., Mazzocca, A., Colombatto, S., Marra, E., Autelli, R., Pinzani, M., Parola, M.
Published in Journal of hepatology (2006)
Published in Journal of hepatology (2006)
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764 ABNORMAL SYSTEMIC BIOMOLECULAR EXPRESSION OF CALCIUM-SENSING RECEPTORS (CARS) IN CIRRHOTIC RATS: A NEW MECHANISM OF DISEASE IN PORTAL HYPERTENSION
Sansoe', G, Aragno, M, Tomasinelli, C, di Bonzo, L. Valfre, Rosina, F, Smedile, A, Rizzetto, M, Parola, M
Published in Journal of hepatology (2009)
Published in Journal of hepatology (2009)
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Journal Article