Optimized libraries for CRISPR-Cas9 genetic screens with multiple modalities
Sanson, Kendall R., Hanna, Ruth E., Hegde, Mudra, Donovan, Katherine F., Strand, Christine, Sullender, Meagan E., Vaimberg, Emma W., Goodale, Amy, Root, David E., Piccioni, Federica, Doench, John G.
Published in Nature communications (21.12.2018)
Published in Nature communications (21.12.2018)
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Journal Article
Creation of Novel Protein Variants with CRISPR/Cas9-Mediated Mutagenesis: Turning a Screening By-Product into a Discovery Tool
Donovan, Katherine F, Hegde, Mudra, Sullender, Meagan, Vaimberg, Emma W, Johannessen, Cory M, Root, David E, Doench, John G
Published in PloS one (24.01.2017)
Published in PloS one (24.01.2017)
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Journal Article
Optimized sgRNA design to maximize activity and minimize off-target effects of CRISPR-Cas9
Doench, John G, Fusi, Nicolo, Sullender, Meagan, Hegde, Mudra, Vaimberg, Emma W, Donovan, Katherine F, Smith, Ian, Tothova, Zuzana, Wilen, Craig, Orchard, Robert, Virgin, Herbert W, Listgarten, Jennifer, Root, David E
Published in Nature biotechnology (01.02.2016)
Published in Nature biotechnology (01.02.2016)
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Journal Article
Orthologous CRISPR–Cas9 enzymes for combinatorial genetic screens
Najm, Fadi J, Strand, Christine, Donovan, Katherine F, Hegde, Mudra, Sanson, Kendall R, Vaimberg, Emma W, Sullender, Meagan E, Hartenian, Ella, Kalani, Zohra, Fusi, Nicolo, Listgarten, Jennifer, Younger, Scott T, Bernstein, Bradley E, Root, David E, Doench, John G
Published in Nature biotechnology (01.02.2018)
Published in Nature biotechnology (01.02.2018)
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Journal Article
Up, down, and out: optimized libraries for CRISPRa, CRISPRi, and CRISPR-knockout genetic screens
Sanson, Kendall R, Hanna, Ruth E, Hegde, Mudra, Donovan, Katherine F, Strand, Christine, Sullender, Meagan E, Vaimberg, Emma W, Goodale, Amy, Root, David E, Piccioni, Federica, Doench, John G
Published in bioRxiv (02.07.2018)
Published in bioRxiv (02.07.2018)
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