Search Results - "Vaidya, Tanaya" :: K.UTB vyhledávací portál

Insights into Doxorubicin-induced Cardiotoxicity: Molecular Mechanisms, Preventive Strategies, and Early Monitoring

by Wenningmann, Nadine, Knapp, Merle, Ande, Anusha, Vaidya, Tanaya R, Ait-Oudhia, Sihem
Published in Molecular pharmacology (01.08.2019)

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In vitro to clinical translational pharmacokinetic/pharmacodynamic modeling of doxorubicin (DOX) and dexrazoxane (DEX) interactions: Safety assessment and optimization

by Mody, Hardik, Vaidya, Tanaya R, Ait-Oudhia, Sihem
Published in Scientific reports (22.02.2023)

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Anticancer and cardio-protective effects of liposomal doxorubicin in the treatment of breast cancer

by Franco, Yesenia L, Vaidya, Tanaya R, Ait-Oudhia, Sihem
Published in Breast cancer targets and therapy (01.01.2018)

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Combining Multiscale Experimental and Computational Systems Pharmacological Approaches to Overcome Resistance to HER2-targeted Therapy in Breast Cancer

by Vaidya, Tanaya R, Ande, Anusha, Ait-Oudhia, Sihem
Published in The Journal of pharmacology and experimental therapeutics (01.06.2019)

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Identification of Novel and Early Biomarkers for Cisplatin-induced Nephrotoxicity and the Nephroprotective Role of Cimetidine using a Pharmacometabolomic-based Approach Coupled with In Vitro Toxicodynamic Modeling and Simulation

by Mody, Hardik, Nair, Sreenath, Rump, Adrian, Vaidya, Tanaya R, Garrett, Timothy J, Lesko, Lawrence, Ait-Oudhia, Sihem
Published in Journal of pharmaceutical sciences (01.01.2024)

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In vitro to clinical translation of combinatorial effects of doxorubicin and dexrazoxane in breast cancer: a mechanism-based pharmacokinetic/pharmacodynamic modeling approach

by Mody, Hardik, Vaidya, Tanaya R., Lezeau, Jovin, Taha, Kareem, Ait-Oudhia, Sihem
Published in Frontiers in pharmacology (19.10.2023)

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$Experimental and computational assessment of the synergistic pharmacodynamic drug–drug interactions of a triple combination therapy in refractory HER2-positive breast cancer cells$

Experimental and computational assessment of the synergistic pharmacodynamic drug–drug interactions of a triple combination therapy in refractory HER2-positive breast cancer cells

by Vaidya, Tanaya R., Ait-Oudhia, Sihem
Published in Journal of pharmacokinetics and pharmacodynamics (01.04.2022)

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Multiscale and Translational Quantitative Systems Toxicology, Pharmacokinetic-Toxicodynamic Modeling Analysis for Assessment of Doxorubicin-Induced Cardiotoxicity

by Vaidya, Tanaya R., Mody, Hardik, Franco, Yesenia L., Brown, Ashley, Ait-Oudhia, Sihem
Published in The AAPS journal (06.01.2021)

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Pharmacodynamic Modeling to Evaluate the Impact of Cimetidine, an OCT2 Inhibitor, on the Anticancer Effects of Cisplatin

by Mody, Hardik, Vaidya, Tanaya R, Lesko, Lawrence J, Ait-Oudhia, Sihem
Published in Cells (Basel, Switzerland) (23.12.2022)

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$A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer$

A quantitative systems pharmacological approach identified activation of JNK signaling pathway as a promising treatment strategy for refractory HER2 positive breast cancer

by Franco, Yesenia L., Ramakrishnan, Vidya, Vaidya, Tanaya R., Mody, Hardik, Perez, Luis, Ait-Oudhia, Sihem
Published in Journal of pharmacokinetics and pharmacodynamics (01.04.2021)

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Utility of a Novel Three-Dimensional and Dynamic (3DD) Cell Culture System for PK/PD Studies: Evaluation of a Triple Combination Therapy at Overcoming Anti-HER2 Treatment Resistance in Breast Cancer

by Ande, Anusha, Vaidya, Tanaya R, Tran, Bao N, Vicchiarelli, Michael, Brown, Ashley N, Ait-Oudhia, Sihem
Published in Frontiers in pharmacology (01.05.2018)

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Abstract 5134: Novel trifunctional immunoliposome delivery system to minimize resistance and side effects for anticancer therapy

by Vaidya, Tanaya R., Ait-Oudhia, Sihem
Published in Cancer research (Chicago, Ill.) (01.07.2017)

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Development and Evaluation of Tri-Functional Immunoliposomes for the Treatment of HER2 Positive Breast Cancer

by Vaidya, Tanaya, Straubinger, Robert M., Ait-Oudhia, Sihem
Published in Pharmaceutical research (01.05.2018)

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Correction to: A Three-dimensional and Dynamic (3DD) Cell Culture System for Evaluation of Pharmacokinetics, Safety and Efficacy of Anti-cancer Drugs

by Vaidya, Tanaya R., Franco, Yesenia L., Ait-Oudhia, Sihem
Published in Current pharmacology reports (18.04.2023)

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Systems pharmacological analysis of mitochondrial cardiotoxicity induced by selected tyrosine kinase inhibitors

by Vaidya, Tanaya, Kamta, Jeff, Chaar, Maher, Ande, Anusha, Ait-Oudhia, Sihem
Published in Journal of pharmacokinetics and pharmacodynamics (01.06.2018)

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