The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes
Raguseo, Federica, Wang, Yiran, Li, Jessica, Petrić Howe, Marija, Balendra, Rubika, Huyghebaert, Anouk, Vadukul, Devkee M., Tanase, Diana A., Maher, Thomas E., Malouf, Layla, Rubio-Sánchez, Roger, Aprile, Francesco A., Elani, Yuval, Patani, Rickie, Di Michele, Lorenzo, Di Antonio, Marco
Published in Nature communications (13.12.2023)
Published in Nature communications (13.12.2023)
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Journal Article
Probing supramolecular protein assembly using covalently attached fluorescent molecular rotors
Kubánková, Markéta, López-Duarte, Ismael, Bull, James A, Vadukul, Devkee, Serpell, Louise, de Saint Victor, Marie, Stride, Eleanor, Kuimova, Marina K
Published in Biomaterials (01.09.2017)
Published in Biomaterials (01.09.2017)
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Journal Article
A Facile Method to Produce N-Terminally Truncated α-Synuclein
Thrush, Rebecca J, Vadukul, Devkee M, Aprile, Francesco A
Published in Frontiers in neuroscience (27.05.2022)
Published in Frontiers in neuroscience (27.05.2022)
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Journal Article
A single-domain antibody detects and neutralises toxic Aβ42 oligomers in the Alzheimer’s disease CSF
Bigi, Alessandra, Napolitano, Liliana, Vadukul, Devkee M., Chiti, Fabrizio, Cecchi, Cristina, Aprile, Francesco A., Cascella, Roberta
Published in Alzheimer's research & therapy (18.01.2024)
Published in Alzheimer's research & therapy (18.01.2024)
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Journal Article
An evaluation of the self-assembly enhancing properties of cell-derived hexameric amyloid-β
Vadukul, Devkee M., Vrancx, Céline, Burguet, Pierre, Contino, Sabrina, Suelves, Nuria, Serpell, Louise C., Quinton, Loïc, Kienlen-Campard, Pascal
Published in Scientific reports (02.06.2021)
Published in Scientific reports (02.06.2021)
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Senescence-related impairment of autophagy induces toxic intraneuronal amyloid-β accumulation in a mouse model of amyloid pathology
Suelves, Nuria, Saleki, Shirine, Ibrahim, Tasha, Palomares, Debora, Moonen, Sebastiaan, Koper, Marta J, Vrancx, Céline, Vadukul, Devkee M, Papadopoulos, Nicolas, Viceconte, Nikenza, Claude, Eloïse, Vandenberghe, Rik, von Arnim, Christine A F, Constantinescu, Stefan N, Thal, Dietmar Rudolf, Decottignies, Anabelle, Kienlen-Campard, Pascal
Published in Acta neuropathologica communications (17.05.2023)
Published in Acta neuropathologica communications (17.05.2023)
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Journal Article
Presenilin-Deficient Neurons and Astrocytes Display Normal Mitochondrial Phenotypes
Contino, Sabrina, Suelves, Nuria, Vrancx, Céline, Vadukul, Devkee M, Payen, Valery L, Stanga, Serena, Bertrand, Luc, Kienlen-Campard, Pascal
Published in Frontiers in neuroscience (22.01.2021)
Published in Frontiers in neuroscience (22.01.2021)
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Journal Article
Structural Determinant of β-Amyloid Formation: From Transmembrane Protein Dimerization to β-Amyloid Aggregates
Papadopoulos, Nicolas, Suelves, Nuria, Perrin, Florian, Vadukul, Devkee M, Vrancx, Céline, Constantinescu, Stefan N, Kienlen-Campard, Pascal
Published in Biomedicines (29.10.2022)
Published in Biomedicines (29.10.2022)
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Journal Article
Dimeric Transmembrane Orientations of APP/C99 Regulate γ-Secretase Processing Line Impacting Signaling and Oligomerization
Perrin, Florian, Papadopoulos, Nicolas, Suelves, Nuria, Opsomer, Rémi, Vadukul, Devkee M., Vrancx, Céline, Smith, Steven O., Vertommen, Didier, Kienlen-Campard, Pascal, Constantinescu, Stefan N.
Published in iScience (18.12.2020)
Published in iScience (18.12.2020)
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Journal Article
Misfolded amyloid-β-42 impairs the endosomal–lysosomal pathway
Marshall, Karen E., Vadukul, Devkee M., Staras, Kevin, Serpell, Louise C.
Published in Cellular and molecular life sciences : CMLS (01.12.2020)
Published in Cellular and molecular life sciences : CMLS (01.12.2020)
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Journal Article
α‑Synuclein Aggregation Is Triggered by Oligomeric Amyloid‑β 42 via Heterogeneous Primary Nucleation
Vadukul, Devkee M., Papp, Marcell, Thrush, Rebecca J., Wang, Jielei, Jin, Yiyun, Arosio, Paolo, Aprile, Francesco A.
Published in Journal of the American Chemical Society (23.08.2023)
Published in Journal of the American Chemical Society (23.08.2023)
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Journal Article
Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid‐β 1‐42
Vadukul, Devkee M., Gbajumo, Oyinkansola, Marshall, Karen E., Serpell, Louise C.
Published in FEBS letters (01.03.2017)
Published in FEBS letters (01.03.2017)
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Journal Article
Galectin-3 shapes toxic alpha-synuclein strains in Parkinson’s disease
García-Revilla, Juan, Boza-Serrano, Antonio, Jin, Yiyun, Vadukul, Devkee M., Soldán-Hidalgo, Jesús, Camprubí-Ferrer, Lluís, García-Cruzado, Marta, Martinsson, Isak, Klementieva, Oxana, Ruiz, Rocío, Aprile, Francesco A., Deierborg, Tomas, Venero, José Luis
Published in Acta neuropathologica (01.07.2023)
Published in Acta neuropathologica (01.07.2023)
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Journal Article
Unveiling the Rational Development of Stimuli-Responsive Silk Fibroin-Based Ionogel Formulations
Shmool, Talia A., Martin, Laura K., Jirkas, Andreas, Matthews, Richard P., Constantinou, Anna P., Vadukul, Devkee M., Georgiou, Theoni K., Aprile, Francesco A., Hallett, Jason P.
Published in Chemistry of materials (08.08.2023)
Published in Chemistry of materials (08.08.2023)
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Journal Article
Mechanism of Cellular Formation and In Vivo Seeding Effects of Hexameric β-Amyloid Assemblies
Vrancx, Céline, Vadukul, Devkee M., Suelves, Nuria, Contino, Sabrina, D’Auria, Ludovic, Perrin, Florian, van Pesch, Vincent, Hanseeuw, Bernard, Quinton, Loïc, Kienlen-Campard, Pascal
Published in Molecular neurobiology (01.12.2021)
Published in Molecular neurobiology (01.12.2021)
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Structure‐dependent effects of amyloid‐β on long‐term memory in Lymnaea stagnalis
Ford, Lenzie, Crossley, Michael, Vadukul, Devkee M., Kemenes, György, Serpell, Louise C.
Published in FEBS letters (01.05.2017)
Published in FEBS letters (01.05.2017)
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Journal Article
A critical role for the self-assembly of Amyloid-β1-42 in neurodegeneration
Marshall, Karen E., Vadukul, Devkee M., Dahal, Liza, Theisen, Alina, Fowler, Milena W., Al-Hilaly, Youssra, Ford, Lenzie, Kemenes, György, Day, Iain J., Staras, Kevin, Serpell, Louise C.
Published in Scientific reports (22.07.2016)
Published in Scientific reports (22.07.2016)
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